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Clinical Trials

Showing trials with last updates posted in November 2025.

NCT07227610 | NOT_YET_RECRUITING | PHASE2
54 Participants

Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-31
Completion: 2029-01-31
Conditions
Brain Metastases Cancer (With CNS Involvement)
Interventions
RADIATION
No Results Yet
NCT07227597 | NOT_YET_RECRUITING | PHASE1/PHASE2
170 Participants

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-12
Completion: 2030-11-29
Conditions
Small Cell Lung Cancer Extensive Stage
Interventions
DRUG
No Results Yet
NCT07227584 | NOT_YET_RECRUITING | PHASE2
67 Participants

ALL Backbone in AYAs

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-04-30
Completion: 2030-07-31
Conditions
Acute Lymphoblastic Leukemia Philadelphia Chromosome-Negative Lymphoblastic Leukemia Acute Lymphoblastic Leukemia (ALL) Leukemia
Interventions
DRUG
No Results Yet
NCT07227571 | NOT_YET_RECRUITING | PHASE1
30 Participants

Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Osteosarcoma, FIERCe Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-05-01
Completion: 2044-01-31
Conditions
Advanced Osteosarcoma
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT07227558 | NOT_YET_RECRUITING | NA
100 Participants

Improving Information Sharing Between Family Caregivers and Home Care Aides

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2027-02-28
Conditions
Shared Care
Interventions
OTHER
No Results Yet
NCT07227545 | NOT_YET_RECRUITING | NA
18 Participants

High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2026-11-30
Conditions
Alcohol Use Disorder (AUD)
Interventions
DEVICE
No Results Yet
NCT07227532 | RECRUITING | NA
276 Participants

A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-21
Completion: 2030-12-31
Conditions
Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT07227519 | NOT_YET_RECRUITING | NA
1000 Participants

Effects of UPF Warning Labels on Social Media Among Teens and Young Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2025-12-20
Conditions
Nutrition Healthy Diet Food Preferences
Interventions
BEHAVIORAL
No Results Yet
NCT07227506 | RECRUITING
50 Participants

Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-20
Completion: 2027-11-01
Conditions
Gerd Eosinophilic Esophagitis
Interventions
DEVICE
No Results Yet
NCT07227493 | RECRUITING
45 Participants

Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-24
Completion: 2027-01-31
Conditions
Open Pilon Fractures
Interventions
DEVICE
No Results Yet
NCT07227480 | NOT_YET_RECRUITING | NA
40 Participants

Advancing Lung Cancer Screening One Text at a Time

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2026-07-31
Conditions
Lung Cancer Screening
Interventions
BEHAVIORAL
No Results Yet
NCT07227467 | RECRUITING
100 Participants

Prospective Assessments Following Immediate Lymphatic Reconstruction

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2030-12-31
Conditions
Lymphatic Reconstruction
Interventions
OTHER
No Results Yet
NCT07227454 | NOT_YET_RECRUITING | PHASE3
258 Participants

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-20
Completion: 2031-04-09
Conditions
Depressive Disorder, Major
Interventions
DRUG OTHER
No Results Yet
NCT07227441 | RECRUITING
200 Participants

Chronic Infections and Inflammation in ME/CFS: An Observational Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2030-09-30
Conditions
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
No Results Yet
NCT07227428 | NOT_YET_RECRUITING | PHASE4
206 Participants

Comparison of Glucocorticoid Tapering Schedules in Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2027-12-31
Conditions
Rheumatoid Arthritis (RA)
Interventions
DRUG
No Results Yet
NCT07227415 | NOT_YET_RECRUITING | PHASE1/PHASE2
224 Participants

A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-04
Completion: 2027-11-02
Conditions
Carcinoma, Renal Cell Advanced Renal Cell Carcinoma Renal Cancer Renal Neoplasm Clear Cell Renal Cell Carcinoma Metastatic Renal Cell Carcinoma Clear-cell Metastatic Renal Cell Carcinoma Carcinoma, Renal Cell Metastasis Advanced or Metastatic Renal Cell Carcinoma Carcinoma, Renal Cell, Advanced Metastatic Renal Cell Cancer Metastatic Renal Cell Carcinoma ( mRCC) Metastatic/Advanced Renal Cell Carcinoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT07227402 | NOT_YET_RECRUITING | PHASE3
904 Participants

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-29
Completion: 2032-02-27
Conditions
Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT07227389 | NOT_YET_RECRUITING
52 Participants

Timing of Opioid Administration and Postoperative Respiratory Depression.

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2028-12-01
Conditions
Opiod-Related Disorders Respiration Rate Detection Post-operative Respiratory Depression
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07227376 | RECRUITING
250 Participants

Data Collection Using Eko Digital Devices in a Clinical Setting

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-14
Completion: 2026-04-01
Conditions
Lung Diseases
Interventions
DEVICE
No Results Yet
NCT07227363 | RECRUITING | NA
40 Participants

Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-02-01
Completion: 2025-12-31
Conditions
PCOS (Polycystic Ovary Syndrome)
Interventions
OTHER DIETARY_SUPPLEMENT
No Results Yet
NCT07227350 | NOT_YET_RECRUITING | PHASE2
180 Participants

L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2030-12-31
Conditions
Locally Advanced Basal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT07227337 | RECRUITING | NA
676 Participants

Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-05
Completion: 2028-12-31
Conditions
Post Traumatic Stress Disorder Depression Violence
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07227324 | RECRUITING
1000 Participants

Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-26
Completion: 2027-04-30
Conditions
Cannabis Use Cancer
No Results Yet
NCT07227311 | NOT_YET_RECRUITING | PHASE2
200 Participants

A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-14
Completion: 2030-07-10
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT07227298 | NOT_YET_RECRUITING | PHASE1/PHASE2
162 Participants

A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-17
Completion: 2029-03-08
Conditions
Advanced/Metastatic Non-Small Cell Lung Cancer Carcinoma, Non-Small Cell Lung Non-Small Cell Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT07227285 | NOT_YET_RECRUITING | PHASE1/PHASE2
16 Participants

Long-term Follow-up Study of Patients Who Received EG110A, a Non-replicative Herpes Simplex Virus 1-derived Gene Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-04-30
Completion: 2031-04-30
Conditions
Urinary Bladder, Overactive Spinal Cord Injury
Interventions
OTHER DRUG
No Results Yet
NCT07227272 | RECRUITING | NA
40 Participants

Early Childhood Dietary Assessment Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-15
Completion: 2026-04-30
Conditions
Dietary Assessment
Interventions
OTHER
No Results Yet
NCT07227259 | RECRUITING | NA
40 Participants

Health Properties of Pecan Nut Consumption

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-15
Completion: 2027-12-31
Conditions
Healthy Adults
Interventions
OTHER
No Results Yet
NCT07227246 | RECRUITING | PHASE3
350 Participants

Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-06
Completion: 2029-01-31
Conditions
Intracerebral Hemorrhage
Interventions
BIOLOGICAL
No Results Yet
NCT07227233 | NOT_YET_RECRUITING | PHASE2
105 Participants

Artificial Intelligence and Machine Learning to Guide CDK4/6 Inhibitor Rechallenge in Breast Cancer.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2027-12-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT07227220 | COMPLETED | EARLY_PHASE1
15 Participants

Summer Youth Employment Programs for Health Promotion

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-31
Completion: 2025-07-07
Conditions
Obesity, Childhood Behavior, Health Healthy Lifestyle
Interventions
BEHAVIORAL
No Results Yet
NCT07227207 | NOT_YET_RECRUITING | PHASE1/PHASE2
72 Participants

A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2029-03-31
Conditions
Alpha-1 Antitrypsin Deficiency (AATD)
Interventions
DRUG
No Results Yet
NCT07227194 | COMPLETED
53065 Participants

Machine Learning Assessment of Next-Day Migraine Likelihood

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-02-07
Completion: 2025-08-01
Conditions
Migraine
No Results Yet
NCT07227181 | COMPLETED | NA
64 Participants

2025 Animal Assisted Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-23
Completion: 2025-08-13
Conditions
Anxiety Trauma Hospitalized Adult Patients Rehabilitation Physical Mobility Impairment Therapy Dog
Interventions
OTHER
No Results Yet
NCT07227168 | RECRUITING | PHASE1
200 Participants

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2027-12-31
Conditions
Head and Neck Squamous Cell Carcinoma HNSCC Non-Small Cell Lung Cancer NSCLC Esophageal Cancer Gastric Cancer Colorectal Cancer Pancreatic Ductal Adenocarcinoma (PDAC) Cervical Cancer Endometrial Cancer Urothelial Cancer
Interventions
DRUG
No Results Yet
NCT07227155 | NOT_YET_RECRUITING
375 Participants

The HOPE Biobank Resource

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-27
Completion: 2031-03-30
Conditions
Aplastic Anemias Hemoglobinopathies Bone Marrow Failure
No Results Yet
NCT07227142 | NOT_YET_RECRUITING | NA
100 Participants

IceBath: NOICE vs Nothing

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-02-01
Completion: 2027-01-31
Conditions
Pain
Interventions
BEHAVIORAL
No Results Yet
NCT07227129 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-11-12
No Results Yet
NCT07227116 | RECRUITING
280 Participants

Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-01
Completion: 2026-04-30
Conditions
Complex Aneuploidy Chaotic Aneuploidy
No Results Yet
NCT07227103 | NOT_YET_RECRUITING | PHASE2/PHASE3
120 Participants

A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Transcranial Magnetic Stimulation for Treatment Resistant Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-03-01
Completion: 2026-12-31
Conditions
Treatment Resistant Depression
Interventions
DEVICE DRUG
No Results Yet
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