The Effectiveness and Efficacy of an Online Cognitive Behavioral Psychotherapeutic Program

NCT ID: NCT07255131

Last Updated: 2025-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-26

Study Completion Date

2028-12-20

Brief Summary

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An online group cognitive behavioral psychotherapeutic program will be offered to patients with cystic fibrosis and to caregivers by the Hellenic Cystic Fibrosis Association. These 2 above therapy groups will be compared with control groups in a randomized controlled trial

Detailed Description

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A therapy group of patients with cystic fibrosis, who participate on the online group cognitive behavioral psychotherapeutic program will be compared with a control group of patients with cystic fibrosis, who participate in an online group supportive psychotherapeutic program. Both of the groups participate on 13 sessions once a week.

A therapy group of caregivers, who participate on the online group cognitive behavioral psychotherapeutic program will be compared with a control group of caregivers, who participate in an online group supportive psychotherapeutic program. Both of the groups participate on 13 sessions once a week.

Conditions

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Depression - Major Depressive Disorder Anxiety Chronic Anxiety Functional Outcome Recovery Obsessive Compulsive Disorders Assertiveness

Keywords

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Cystic Fibrosis Group cognitive behavioral psychotherapy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A therapy group with patients with cystic fibrosis will be compared with a control group with patients with cystic fibrosis. A therapy group with caregivers will be compared with a control group with cqaregivers
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Therapy group A patients with Cystic Fibrosis

Participation on an online group cognitive behavioral psychotherapy via Zoom in 13 sessions.

Group Type EXPERIMENTAL

Group A An online group cognitive behavioral psychotherapy in 13 sessions via Zoom

Intervention Type BEHAVIORAL

An online group cognitive behavioral psychotherapy will be offered via Zoom in 13 sessions to the therapy Group A, to patients with cystic fibrosis

Control group B Patients with cystic fibrosis

Participation on an online group supportive psychotherapy via Zoom in 13 sessions.

Group Type ACTIVE_COMPARATOR

Group B An online group supportive psychotherapy in 13 sessions via Zoom

Intervention Type BEHAVIORAL

An online group supportive psychotherapy will be offered via Zoom in 13 sessions to the control group Group B, to patients with cystic fibrosis

Therapy group C caregivers of patients with cystic fibrosis

Participation on an online group cognitive behavioral psychotherapy via Zoom in 13 sessions.

Group Type EXPERIMENTAL

Group C An online group cognitive behavioral psychotherapy in 13 sessions via Zoom

Intervention Type BEHAVIORAL

An online group cognitive behavioral psychotherapy will be offered via Zoom in 13 sessions to the therapy group C, to caregivers of patients with cystic fibrosis

Contol group D caregivers of patients with cystic fibrosis

Participation on an online group supportive psychotherapy via Zoom in 13 sessions.

Group Type ACTIVE_COMPARATOR

Group D An online group supportive psychotherapy in 13 sessions via Zoom

Intervention Type BEHAVIORAL

An online group supportive psychotherapy will be offered via Zoom in 13 sessions to the control Group D, to caregivers of patients with cystic fibrosis

Interventions

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Group A An online group cognitive behavioral psychotherapy in 13 sessions via Zoom

An online group cognitive behavioral psychotherapy will be offered via Zoom in 13 sessions to the therapy Group A, to patients with cystic fibrosis

Intervention Type BEHAVIORAL

Group B An online group supportive psychotherapy in 13 sessions via Zoom

An online group supportive psychotherapy will be offered via Zoom in 13 sessions to the control group Group B, to patients with cystic fibrosis

Intervention Type BEHAVIORAL

Group C An online group cognitive behavioral psychotherapy in 13 sessions via Zoom

An online group cognitive behavioral psychotherapy will be offered via Zoom in 13 sessions to the therapy group C, to caregivers of patients with cystic fibrosis

Intervention Type BEHAVIORAL

Group D An online group supportive psychotherapy in 13 sessions via Zoom

An online group supportive psychotherapy will be offered via Zoom in 13 sessions to the control Group D, to caregivers of patients with cystic fibrosis

Intervention Type BEHAVIORAL

Other Intervention Names

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Experimental Active comparator Experimental Active comparator

Eligibility Criteria

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Inclusion Criteria

* Age 18-70
* Members of the Hellenic Cystic Fibrosis Association
* Willingness to participate on 13 sessions via Zoom

Exclusion Criteria

* Age over 70
* Not members of the Hellenic Cystic Fibrosis Association
* Not able to participate on 13 sessions via Zoom
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rakitzi, Stavroula

OTHER

Sponsor Role lead

Responsible Party

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Dr. Stavroula Rakitzi

PhD, Clinical psychologist and cognitive behavioral psychotherapist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dr. Stavroula Rakitzi

Role: STUDY_CHAIR

Private Practice

Locations

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Private practice, ILISION 34 15771 Athens Greece

Athens, , Greece

Site Status RECRUITING

Countries

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Greece

Central Contacts

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Dr. Stavroula Rakitzi, PhD

Role: CONTACT

Phone: +306989766935

Email: [email protected]

Mrs Anna Spinou, President of the Hellenic Cystic Fibrosis Association, Msc

Role: CONTACT

Phone: +306944255853

Email: [email protected]

Facility Contacts

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Dr. Stavroula Rakitzi, PhD

Role: primary

Mrs Anna Spinou, President of the Hellenic Cystic Fibrosis Association, Msc

Role: backup

References

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Bech, P. (1993). Rating scales for Psychopathology, Health Status and Quality of Life. Springer-Verlag.

Reference Type BACKGROUND

Αntoniou, V., Εfthimiou, Κ., & Μilona, Κ.(2015). Social anxiety and assertiveness. A structured group cognitive behavioral program. IETHS.

Reference Type BACKGROUND

Fiedler, P. (2005). Verhaltenstherapie in Gruppen. Beltz.

Reference Type BACKGROUND

Cohen, J. (1988). Statistical Power Analyses for the Behavioural Sciences. Erlbaum.

Reference Type BACKGROUND

Rakitzi, S., Spinou, A., & Giannaki, K. (2025). The effectiveness of an online-group cognitive behavioral psychotherapy in Hellenic Cystic Fibrosis Association for patients and caregivers. Journal of rational emotive and cognitive behavior therapy. DOI: 10.1007/s10942-025-00611-3

Reference Type BACKGROUND

Rakitzi, S. (2023). Clinical psychology and cognitive behavioral psychotherapy. Recovery in mental health. Springer.

Reference Type BACKGROUND

Mayr, S., Erdfelder, E., Buchner, A., & Faul, F. (2007). A short tutorial of G-Power. Tutorials in Quantitative Methods in Psychology, 3(2), 51-59.

Reference Type BACKGROUND

Koumpouros, Y., Papageorgiou, E., Sakellari, E., Prapas, X., Perifanou, D., & Lagiou, A. (2018). Adaptation and psychometric properties' evaluation of the Greek version of WHODAS 2.0. Pilot application in Greek elderly population. Health Services and Outcomes Research Methodology, 18(1), 63-74. https://doi.org/10.1007/s10742-017-0176-x.

Reference Type BACKGROUND

Hofmann SG, Asnaani A, Vonk IJ, Sawyer AT, Fang A. The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses. Cognit Ther Res. 2012 Oct 1;36(5):427-440. doi: 10.1007/s10608-012-9476-1. Epub 2012 Jul 31.

Reference Type BACKGROUND
PMID: 23459093 (View on PubMed)

Hancock N, Scanlan JN, Honey A, Bundy AC, O'Shea K. Recovery Assessment Scale - Domains and Stages (RAS-DS): Its feasibility and outcome measurement capacity. Aust N Z J Psychiatry. 2015 Jul;49(7):624-33. doi: 10.1177/0004867414564084. Epub 2014 Dec 19.

Reference Type BACKGROUND
PMID: 25526940 (View on PubMed)

HAMILTON M. A rating scale for depression. J Neurol Neurosurg Psychiatry. 1960 Feb;23(1):56-62. doi: 10.1136/jnnp.23.1.56. No abstract available.

Reference Type BACKGROUND
PMID: 14399272 (View on PubMed)

Fountoulakis KN, Iacovides A, Kleanthous S, Samolis S, Gougoulias K, St Kaprinis G, Bech P. The Greek translation of the symptoms rating scale for depression and anxiety: preliminary results of the validation study. BMC Psychiatry. 2003 Dec 10;3:21. doi: 10.1186/1471-244X-3-21.

Reference Type BACKGROUND
PMID: 14667249 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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HELLENIC CYSTIC FIBROSIS ASSOC

Identifier Type: OTHER

Identifier Source: secondary_id

RAKITZI CYSTIC FIBROSIS

Identifier Type: -

Identifier Source: org_study_id