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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07312071 | COMPLETED | NA
30 Participants

Vasopressor Use Improves Macrocirculation, But What Are Its Effects on Microcirculation?

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-04-01
Completion: 2023-08-31
Conditions
Septic Shock Sepsis Tissue Ischemia Hemodynamic Instability
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07312045 | RECRUITING
180 Participants

HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-11-25
Completion: 2026-11-25
Conditions
Periodontal Diseases Periodontitis Gingivitis; Chronic
Interventions
PROCEDURE
No Results Yet
NCT07312032 | RECRUITING | NA
20 Participants

The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-13
Completion: 2026-12-01
Conditions
Trauma Injury
Interventions
DEVICE
No Results Yet
NCT07312006 | NOT_YET_RECRUITING | NA
74 Participants

Comparison of AirSeal to DV5 Insufflation in Gastric Sleeve Procedures - The "CAT5-GS" Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-30
Completion: 2026-10-30
Conditions
Pain, Postoperative
Interventions
DEVICE
No Results Yet
NCT07311967 | NOT_YET_RECRUITING | NA
15 Participants

Short-Term Health Outcomes of Cooking UFP Exposure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-02
Completion: 2026-03-01
Conditions
Cognitive Function Decline Air Pollution Exposure Respiratory Inflammation
Interventions
OTHER
No Results Yet
NCT07311954 | NOT_YET_RECRUITING
800 Participants

Development and Validation of a cCTA and Biomarker Based Risk Model for Coronary Revascularization in Elderly Patients With Coronary Artery Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-01
Completion: 2029-01-01
Conditions
Coronary Artery Disease Elderly (Aged >70)
Interventions
OTHER
No Results Yet
NCT07311941 | RECRUITING
1000 Participants

Rapid Escalation of LipiD Lowering Therapy to Reduce RecUrrent Cardiovascular Event

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-30
Completion: 2030-12-31
Conditions
Hyperlipidemia Cardio Vascular Disease
No Results Yet
NCT07311928 | RECRUITING | NA
200 Participants

HELIOS: Human Embryo Illumination to Enhance Development

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-03
Completion: 2027-06-01
Conditions
IVF Outcomes
Interventions
OTHER
No Results Yet
NCT07311902 | RECRUITING | NA
60 Participants

M-Tapa Block and Transversus Abdominal Plane Block for Postoperative Analgesia in Unilateral Open Inguinal Hernia Repair Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-01
Completion: 2025-04-01
Conditions
Pain Management Mtapa Block TAP Block
Interventions
PROCEDURE
No Results Yet
NCT07311889 | NOT_YET_RECRUITING
300 Participants

Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-01
Completion: 2026-06-01
Conditions
Postoperative Pain Postoperative Edema Postoperative Ecchymosis Surgical Wound Healing Postsurgical Recovery
Interventions
OTHER
No Results Yet
NCT07311876 | NOT_YET_RECRUITING | NA
30 Participants

Clinical Lymphedema Evaluation - Advancing Reconstruction of Head and Neck Lymphatics With Symani

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-30
Completion: 2027-03-03
Conditions
Lymphedema Lymphedema of Face Internal Lymphedema External Lymphedema Lymphedema of Neck
Interventions
DEVICE
No Results Yet
NCT07311863 | NOT_YET_RECRUITING | EARLY_PHASE1
6 Participants

UGX202 Injection in Patients With Advanced Retinitis Pigmentosa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-31
Completion: 2027-03-31
Conditions
Retinitis Pigmentosa (RP)
Interventions
GENETIC
No Results Yet
NCT07311850 | RECRUITING | PHASE3
3500 Participants

Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-29
Completion: 2027-09-30
Conditions
Obesity and Overweight
Interventions
DRUG
No Results Yet
NCT07311837 | NOT_YET_RECRUITING
46 Participants

Investigating the Relationships Between Body Composition, Peripheral Muscle Strength, and Cough Force in Healthy Young Adults

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2026-02-15
Completion: 2026-03-01
Conditions
Healthy Young Adults
No Results Yet
NCT07311824 | NOT_YET_RECRUITING | NA
200 Participants

Pain Management for In-Office Gynecologic Procedures Using a Risk-Stratification Pain Calculator

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-29
Completion: 2027-02-28
Conditions
Pain Management Patient Satisfaction Gynecologic Procedures
Interventions
OTHER
No Results Yet
NCT07311811 | NOT_YET_RECRUITING | PHASE1
60 Participants

A Study to Evaluate the Pharmacokinetics and Safety of IN-M00007 and IN-R00007 in Healthy Adult Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-31
Completion: 2026-03-31
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT07311798 | NOT_YET_RECRUITING
300 Participants

Impact of Vascular Resection on Survival and Postoperative Outcomes in Patients With Hilar Cholangiocarcinoma: A Retrospective Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-31
Completion: 2026-01-31
Conditions
Cholangiocarcinoma, Hilar
Interventions
OTHER
No Results Yet
NCT07311785 | NOT_YET_RECRUITING | NA
30 Participants

Accuracy of Maxillary Fixation Using Custom Plates on Nasal Buttress Only Via Minimally Invasive Approach Versus Custom Plates on Nasal and Zygomatic Buttresses Via Conventional Approach in Orthognathic Surgeries

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-31
Completion: 2026-06-30
Conditions
Orthognathic Surgery
Interventions
PROCEDURE
No Results Yet
NCT07311772 | RECRUITING | PHASE3
244 Participants

Prevention and Treatment of Radiation-Induced Oral Mucositis in NPC With Houyanqing Oral Liquid

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-15
Completion: 2027-03-15
Conditions
Nasopharyngeal Cancinoma (NPC) Radiation-induced Oral Mucositis
Interventions
DRUG OTHER
No Results Yet
NCT07311759 | ACTIVE_NOT_RECRUITING | PHASE3
21 Participants

Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-17
Completion: 2025-12-04
Conditions
Chronic Paronychia
Interventions
DRUG
No Results Yet
NCT07311746 | NOT_YET_RECRUITING | PHASE1/PHASE2
36 Participants

Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-06-01
Completion: 2029-01-31
Conditions
T-cell Prolymphocytic Leukemia Refractory T-Cell Prolymphocytic Leukemia
Interventions
DRUG
No Results Yet
NCT07311733 | NOT_YET_RECRUITING | NA
28 Participants

Milky Way Sensor: Device Validation for Infiltrated Tissues

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-31
Completion: 2026-02-28
Conditions
Infiltration of Peripheral IV Therapy
Interventions
DEVICE
No Results Yet
NCT07311720 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-12-31
No Results Yet
NCT07311707 | COMPLETED | NA
60 Participants

Primary Closure vs Open Technique for Pilonidal Sinus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-07-01
Completion: 2023-12-31
Conditions
Pilonidal Sinus Disease Sacrococcygeal Pilonidal Sinus Chronic Infected Sinus Tract Post-surgical Wound Healing
Interventions
PROCEDURE
No Results Yet
NCT07311694 | NOT_YET_RECRUITING | PHASE3
370 Participants

A Phase III Study Comparing HRS-4357 With Novel Androgen Receptor Pathway Inhibitors in Patients With Progressive, PSMA-Positive Metastatic Castration-Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-31
Completion: 2027-12-31
Conditions
PSMA-Positive Progressive Metastatic Castration-Resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT07311681 | COMPLETED | NA
106 Participants

Stepwise Versus Conventional Training in Laparoscopic Suturing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2020-10-14
Completion: 2023-06-30
Conditions
Learning Outcomes of Laparoscopic Suturing
Interventions
OTHER
No Results Yet
NCT07311668 | NOT_YET_RECRUITING
100 Participants

Validation of the Accuracy of an AI-Based System for Diagnosing Depressive Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2026-02-01
Completion: 2026-03-15
Conditions
Depressive Disorder
No Results Yet
NCT07311655 | NOT_YET_RECRUITING
100 Participants

Validation of the Accuracy of an AI-Based System for Diagnosing Anxiety Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2026-02-01
Completion: 2026-03-15
Conditions
Anxiety Disorders
No Results Yet
NCT07311642 | NOT_YET_RECRUITING | NA
88 Participants

The Effect of Intraoperative Binaural Beats on Remimazolam Dose Required for Maintenance of General Anesthesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-31
Completion: 2026-12-01
Conditions
Breast Reconstruction
Interventions
DEVICE
No Results Yet
NCT07311629 | NOT_YET_RECRUITING
450 Participants

Workplace Violence and Safety Perception Among ENT Physicians in Turkey

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-02
Completion: 2026-06-01
Conditions
Workplace Violence Perceived Safety Occupational Health Otolaryngology-Head and Neck Surgery Physicians
Interventions
OTHER
No Results Yet
NCT07311616 | NOT_YET_RECRUITING | NA
50 Participants

A Study on the Effectiveness of Preventive Extensive Release of the Rotator Interval and Joint Capsule to Reduce Postoperative Stiffness in Arthroscopic Rotator Cuff Repair

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-22
Completion: 2027-12-01
Conditions
Supraspinatus Tear
Interventions
PROCEDURE
No Results Yet
NCT07311603 | NOT_YET_RECRUITING | PHASE1
138 Participants

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-02
Completion: 2028-09-20
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT07311590 | NOT_YET_RECRUITING | NA
4 Participants

A First-in-human Clinical Trial Evaluating a Novel Colonic Intraluminal Endoscopic Support Structure (CIESS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-18
Completion: 2026-12-18
Conditions
Colon Polyp
Interventions
DEVICE
No Results Yet
NCT07311577 | RECRUITING | PHASE2
43 Participants

Disitamab Vedotin Combined With Platinum and Bevacizumab as First-Line and Maintenance Therapy for HER2-Expressing, HRD-Negative High-Risk Ovarian Cancer: A Multicenter, Non-Randomized, Single-Arm Phase II Clinical Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-01
Completion: 2027-12-30
Conditions
Ovarian Cancer Metastatic Ovarian Cancer Metastatic Recurrent
Interventions
DRUG
No Results Yet
NCT07311551 | NOT_YET_RECRUITING | PHASE4
112 Participants

A Comparison of Effectiveness, Safety, and Cost-effectiveness of Dapagliflozin and Empagliflozin in Patients With Type 2 Diabetes Mellitus and High Body Mass Index (BMI)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-24
Completion: 2026-12-31
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
NCT07311538 | NOT_YET_RECRUITING | PHASE2
56 Participants

Phase IIa Study of BRY812 Monotherapy in Advanced Gynecological Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-31
Completion: 2027-12-31
Conditions
Advanced Gynecological Malignancies
Interventions
DRUG
No Results Yet
NCT07311512 | NOT_YET_RECRUITING | NA
30 Participants

PMPR and Chlorhexidine on Periodontal Disease and Vascular Function

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-23
Completion: 2028-07-01
Conditions
Periodontal Disease (PD) Cardio Vascular Disease Oral-Systemic Link Vascular Dysfunction Endothelial Function and Arterial Stiffness
Interventions
OTHER
No Results Yet
NCT07311499 | NOT_YET_RECRUITING | NA
60 Participants

Improvement of Sleep in COPD Patients Through Inhalation Management Education by Nurse.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-31
Completion: 2026-12-31
Conditions
Chronic Obstructive Lung Disease
Interventions
BEHAVIORAL
No Results Yet
NCT07311486 | RECRUITING
1000 Participants

Implementation of Biomarker-Based Care for mTBI - IMPACTS-BRAINI Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-07-15
Completion: 2026-05-01
Conditions
Mild Traumatic Brain Injury (mTBI)
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07311473 | COMPLETED | NA
150 Participants

Comprehensive Outcomes of Palatal TSADs Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-01-03
Completion: 2025-09-10
Conditions
Malocclusions
Interventions
DEVICE
No Results Yet
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