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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06392464 | COMPLETED
106 Participants

Validation of Naevia Medical in Valvulopathies

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-27
Completion: 2025-01-24
Conditions
Heart Valve Disease
Interventions
DEVICE
Results Available
NCT06389539 | RECRUITING | NA
220 Participants

Synbiotic to Attenuate Resorption of the Skeleton

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-12
Completion: 2028-04-30
Conditions
Osteoporosis Inflammation Aging
Interventions
OTHER
No Results Yet
NCT06366789 | RECRUITING | PHASE1
150 Participants

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-05-29
Completion: 2026-01-31
Conditions
AML With Gene Mutations
Interventions
DRUG
No Results Yet
NCT06362005 | COMPLETED | PHASE4
50 Participants

The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-05-01
Completion: 2025-07-01
Conditions
Lichen Planus, Oral
Interventions
DRUG
No Results Yet
NCT06359808 | RECRUITING
152 Participants

Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-04-01
Completion: 2026-06-30
Conditions
Colitis, Ulcerative Sleep Quality Gastrointestinal Microbiome Autonomic Nervous System Imbalance
No Results Yet
NCT06354673 | COMPLETED | NA
205 Participants

Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-04-04
Completion: 2025-09-04
Conditions
Paroxysmal Sympathetic Hyperactivity
Interventions
PROCEDURE DRUG
No Results Yet
NCT06352788 | RECRUITING | NA
35 Participants

From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-07-02
Completion: 2027-08-31
Conditions
Foot Injury
Interventions
DEVICE
No Results Yet
NCT06350006 | RECRUITING | PHASE1
924 Participants

SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-05-29
Completion: 2027-12-30
Conditions
CLDN18.2-positive Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06341712 | ACTIVE_NOT_RECRUITING | PHASE2
10 Participants

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-22
Completion: 2026-10-26
Conditions
Osteosarcoma Osteosarcoma in Children Osteosarcoma in Adolescents and Young Adults
Interventions
DRUG OTHER
No Results Yet
NCT06326047 | COMPLETED | PHASE2
299 Participants

A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-18
Completion: 2025-09-19
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT06295952 | RECRUITING | PHASE2
10 Participants

A Study of Pasireotide in People With Prolactinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-02-27
Completion: 2027-02-28
Conditions
Prolactin-Producing Pituitary Tumor
Interventions
DRUG OTHER
No Results Yet
NCT06295432 | RECRUITING | PHASE2
90 Participants

A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-06-01
Completion: 2026-12-31
Conditions
Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06294678 | ACTIVE_NOT_RECRUITING | PHASE3
198 Participants

Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-01
Completion: 2025-09-30
Conditions
Acute Graft-versus-host Disease
Interventions
PROCEDURE
No Results Yet
NCT06293898 | RECRUITING | PHASE1
280 Participants

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-02-09
Completion: 2025-12-24
Conditions
Endometrial Cancer Cervical Cancer Ovarian Cancer Urothelial Carcinoma Biliary Tract Cancer Breast Cancer Lung Cancer Gastric Cancer Gastroesophageal-junction Cancer Esophageal Cancer
Interventions
DRUG
No Results Yet
NCT06261528 | ENROLLING_BY_INVITATION | PHASE1
20 Participants

Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-04-18
Completion: 2026-07-01
Conditions
Progressive Multiple Sclerosis
Interventions
DEVICE
No Results Yet
NCT06260800 | COMPLETED
76 Participants

Spanish Version of Credibility and Expectancy Questionnaire in Patients With Musculoskeletal Injuries

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-01-08
Completion: 2024-07-15
Conditions
Validation Study
Interventions
OTHER
No Results Yet
NCT06238128 | ACTIVE_NOT_RECRUITING | NA
773 Participants

Opioid Rapid Response System: Naloxone Training in Communities

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-05-24
Completion: 2026-01-30
Conditions
Opioid Overdose
Interventions
BEHAVIORAL
No Results Yet
NCT06232577 | ACTIVE_NOT_RECRUITING | PHASE2
170 Participants

5x-Multiplier vs 3-Tier Model for Discharge Opioid Prescriptions After Intra-abdominal Cancer Surgery: A Randomized Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-27
Completion: 2026-02-28
Conditions
Intra-abdominal Cancer
Interventions
DRUG
No Results Yet
NCT06219616 | COMPLETED | NA
80 Participants

Prediction of BK Virus Reactivation in Kidney Transplant Recipient

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-05-01
Completion: 2025-03-30
Conditions
Kidney Transplant Infection BK Virus Infection BK Virus Nephropathy
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06210633 | RECRUITING
1000 Participants

Prospective Registry of Endovascular Thrombectomy for eXtra-Large Ischemic Stroke

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-01-20
Completion: 2025-12-31
Conditions
Acute Ischemic Stroke (AIS) Acute Ischemic Stroke From Large Vessel Occlusion
Interventions
OTHER
No Results Yet
NCT06192615 | RECRUITING | PHASE3
1800 Participants

Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-01-06
Completion: 2027-10-31
Conditions
Delirium
Interventions
DRUG
No Results Yet
NCT06185673 | RECRUITING | PHASE1/PHASE2
30 Participants

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-11-28
Completion: 2030-11-30
Conditions
Oculopharyngeal Muscular Dystrophy
Interventions
GENETIC
No Results Yet
NCT06181370 | RECRUITING | PHASE1
145 Participants

Phase I Study to Assess Safety, Tolerability, PK and PD of AGMB-447 in Healthy Participants and Participants With IPF

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-12-01
Completion: 2026-06-30
Conditions
IPF
Interventions
DRUG OTHER
No Results Yet
NCT06174155 | ACTIVE_NOT_RECRUITING | NA
60 Participants

Comparative Study Between Botulinum Toxin-A Injection and Shock Waves on Hypertrophic Scars in Hand-burned Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-12-15
Completion: 2024-03-05
Conditions
Hand-burned Children
Interventions
OTHER
No Results Yet
NCT06168071 | ENROLLING_BY_INVITATION | NA
10 Participants

Transauricular Vagus Nerve Stimulation in Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-11-15
Completion: 2026-05-31
Conditions
Hypoxia-Ischemia, Brain
Interventions
DEVICE
No Results Yet
NCT06161376 | RECRUITING
400 Participants

Role of Urinary Sphingosine 1-Phosphate as a Biomarker for Detrusor Hyperactivity in Multiple Sclerosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2023-12-04
Completion: 2027-12-31
Conditions
Multiple Sclerosis
Interventions
OTHER
No Results Yet
NCT06161363 | COMPLETED
102 Participants

Description of Compliance With Hydroxychloroquine Treatment in Patients With Systemic Lupus Erythematosus

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2023-11-27
Completion: 2024-11-16
Conditions
Lupus Erythematosus
Interventions
OTHER
No Results Yet
NCT06137625 | RECRUITING | NA
68 Participants

Rhythm Effect on Dance Learning in Typical Development Children and Children With Motor Disorders.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-07-02
Completion: 2027-01-31
Conditions
Cerebral Palsy (CP)
Interventions
BEHAVIORAL
No Results Yet
NCT06137326 | COMPLETED | NA
60 Participants

PEMF vs Laser for Stress Urinary Incontinence

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-11-17
Completion: 2025-01-21
Conditions
Stress Urinary Incontinence
Interventions
DEVICE
No Results Yet
NCT06137274 | ACTIVE_NOT_RECRUITING | PHASE2
25 Participants

Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-12-14
Completion: 2026-11-30
Conditions
Squamous Cell Carcinoma Head and Neck Cancer
Interventions
RADIATION OTHER
No Results Yet
NCT06132516 | ACTIVE_NOT_RECRUITING | NA
50 Participants

Effects of HIIT on HRV in Sub-acute Post-stroke Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-15
Completion: 2027-09-30
Conditions
Stroke
Interventions
OTHER
No Results Yet
NCT06127316 | RECRUITING | NA
20 Participants

The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-16
Completion: 2026-06-01
Conditions
Traumatic Lower Limb Injury
Interventions
DEVICE
No Results Yet
NCT06127264 | RECRUITING | NA
60 Participants

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-01
Completion: 2026-12-31
Conditions
Healthy Ankle Foot Orthosis (AFO) Peripheral Neuropathy
Interventions
DEVICE
No Results Yet
NCT06118281 | RECRUITING | PHASE3
10000 Participants

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-06-25
Completion: 2026-09-03
Conditions
Cardiovascular Risk Acute Myocardial Infarction (AMI)
Interventions
DRUG
No Results Yet
NCT06112418 | RECRUITING | NA
7500 Participants

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-06
Completion: 2029-03-05
Conditions
Diabetes Mellitus, Type 2 PreDiabetes Metabolic Syndrome
Interventions
DEVICE
No Results Yet
NCT06103838 | RECRUITING | PHASE2
60 Participants

18F-Fluciclovine PET/CT in Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-25
Completion: 2026-12-06
Conditions
Multiple Myeloma Newly Diagnosed Multiple Myeloma (NDMM) Relapsed and/or Refractory Multiple Myeloma (RRMM)
Interventions
DRUG PROCEDURE
No Results Yet
NCT06089616 | RECRUITING
100 Participants

A Study to Document and to Further Describe Long-term Safety and Effectiveness of Palovarotene in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-05
Completion: 2035-12-05
Conditions
Fibrodysplasia Ossificans Progressiva
No Results Yet
NCT06084338 | RECRUITING | PHASE2
60 Participants

Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-12-14
Completion: 2027-11-29
Conditions
Prostate Cancer
Interventions
RADIATION DRUG
No Results Yet
NCT06083038 | ACTIVE_NOT_RECRUITING
15 Participants

Utilizing Continuous Glucose Monitoring to Characterize and Manage Hyperglycemia in Patients Initiating Alpelisib

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2023-10-05
Completion: 2025-01-13
Conditions
Metastatic Breast Cancer
Interventions
DRUG DEVICE
No Results Yet
NCT06072196 | COMPLETED
3017 Participants

A Study to Learn About Novel Hormonal Therapies in People With Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2023-10-04
Completion: 2024-12-18
Conditions
Prostatic Neoplasms
Interventions
DRUG
Results Available
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