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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06649682 | SUSPENDED | PHASE1
20 Participants

68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-21
Completion: 2026-10-31
Conditions
Clear Cell Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT06625047 | COMPLETED | PHASE4
30 Participants

Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-07
Completion: 2025-11-12
Conditions
Astrocytoma, IDH-Mutant Glioblastoma Glioma Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted
Interventions
BEHAVIORAL OTHER DRUG
No Results Yet
NCT06600802 | RECRUITING | NA
120 Participants

Intrinsic Validity of Molecular Marker(s) Detection on Tissular Tumoral DNA to Predict the Efficacy of 177Lutetium-PSMA-617 (Lu-PSMA) Treatment for Castration-resistant Metastatic Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-08
Completion: 2034-06-30
Conditions
Castration-resistant Metastatic Prostate Cancer Treated by 177Lutetium-PSMA-617 (Lu-PSMA)
Interventions
BIOLOGICAL
No Results Yet
NCT06597747 | COMPLETED | NA
20 Participants

Design Improvements With SONNET 3

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-16
Completion: 2025-05-22
Conditions
Hearing Loss, Sensorineural
Interventions
DEVICE
Results Available
NCT06585774 | RECRUITING | PHASE3
240 Participants

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-01-21
Completion: 2027-09-28
Conditions
Chronic Graft-versus-host-disease
Interventions
DRUG
No Results Yet
NCT06576024 | COMPLETED | PHASE4
392 Participants

Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in HIV-infected People

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-12-19
Completion: 2025-04-25
Conditions
Hepatitis A Immunodeficiency HIV Infections
Interventions
BIOLOGICAL
No Results Yet
NCT06571448 | ACTIVE_NOT_RECRUITING | PHASE2
138 Participants

Efficacy, Safety, and Tolerability of SR750 in Patients With Trigeminal Neuralgia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-09-16
Completion: 2026-01-31
Conditions
Trigeminal Neuralgia
Interventions
DRUG
No Results Yet
NCT06568718 | COMPLETED | NA
229 Participants

Efficacy and Safety of Longidaze in the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-03-20
Completion: 2024-02-09
Conditions
Lower Urinary Tract Symptoms Prostatic Hyperplasia
Interventions
DRUG
No Results Yet
NCT06568094 | RECRUITING | PHASE1/PHASE2
100 Participants

A Study of HRS-5041 Tablets Combined With Antitumor Therapy in Subjects With Advanced Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-09-25
Completion: 2026-06-30
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06567704 | RECRUITING
20 Participants

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-03-26
Completion: 2026-08-30
Conditions
Non-small Cell Lung Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06567041 | COMPLETED | PHASE1
82 Participants

A Research Study of How Safe a New Medicine Called NNC0519 0130 is and to Test Its Effect in People Living With Excess Body Weight With or Without Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-07
Completion: 2025-12-10
Conditions
Diabetes Mellitus, Type 2 Obesity
Interventions
DRUG
No Results Yet
NCT06566690 | RECRUITING
56 Participants

The Association Between Sensory Block Level, Oxygen Therapy, and ORi in Varicose Vein Patients Undergoing Spinal Anesthesia (ORi: Oxygen Reserve Index)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-29
Completion: 2026-01-22
Conditions
Hyperoxia Hypoxia
Interventions
DEVICE
No Results Yet
NCT06559891 | RECRUITING | NA
261 Participants

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-03
Completion: 2026-02-28
Conditions
Hypertension
Interventions
DEVICE OTHER
No Results Yet
NCT06539338 | RECRUITING | PHASE1
34 Participants

A Study to Investigate Safety of INT2104 Infusions in Participants Aged 18 Years of Age and Older Who Have B-cell Cancers That Came Back After Previous Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-07
Completion: 2028-03-31
Conditions
Lymphomas Non-Hodgkin's B-Cell Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions
GENETIC
No Results Yet
NCT06531499 | RECRUITING | PHASE1
106 Participants

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-11
Completion: 2028-11-24
Conditions
Metastatic Castration-Resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06524427 | RECRUITING | NA
1124 Participants

Robot-Assisted vs. Video-Assisted Lobectomy for NSCLC (RAVAR)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2020-08-25
Completion: 2030-12-31
Conditions
Non Small Cell Lung Cancer
Interventions
PROCEDURE
No Results Yet
NCT06516965 | RECRUITING | PHASE3
330 Participants

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-10
Completion: 2026-10-19
Conditions
Prurigo Nodularis
Interventions
DRUG
No Results Yet
NCT06516952 | RECRUITING | PHASE3
330 Participants

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-10
Completion: 2026-10-19
Conditions
Prurigo Nodularis
Interventions
DRUG
No Results Yet
NCT06512558 | RECRUITING | NA
20 Participants

Augmented Reality Feasibility for Non-invasive Preoperative Tracking in Breast Cancer Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-14
Completion: 2027-11-01
Conditions
Subclinical Breast Cancer Lesion
Interventions
PROCEDURE
No Results Yet
NCT06506773 | COMPLETED
79 Participants

Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-07-09
Completion: 2025-11-27
Conditions
Cystic Fibrosis
No Results Yet
NCT06482463 | RECRUITING | NA
185 Participants

Diagnostic of D-lactate in Cerebrospinal Fluid Level in Patients With Suspected Ventriculostomy-related Meningitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-02-12
Completion: 2027-02-28
Conditions
Nosocomial Infection
Interventions
BIOLOGICAL
No Results Yet
NCT06480227 | RECRUITING | NA
358 Participants

Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-28
Completion: 2028-01-01
Conditions
Stress Urinary Incontinence Urinary Incontinence Mixed Urinary Incontinence
Interventions
DEVICE
No Results Yet
NCT06477354 | COMPLETED | NA
64 Participants

ACEMg Hearing Preservation, Tinnitus and Hyperacusis Relief

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-18
Completion: 2025-12-23
Conditions
Sensorineural Hearing Loss Tinnitus SNHL Inner Ear Hearing Loss
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06460961 | ACTIVE_NOT_RECRUITING | PHASE1
168 Participants

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-07-14
Completion: 2027-07-13
Conditions
Neoplasm Metastasis
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06452732 | RECRUITING
283 Participants

Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AML

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-01
Completion: 2026-06-30
Conditions
Acute Myeloid Leukemia Acute Lymphoblastic Leukemia
Interventions
OTHER
No Results Yet
NCT06447168 | RECRUITING
424 Participants

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-14
Completion: 2032-07-15
Conditions
Primary Biliary Cholangitis
No Results Yet
NCT06440967 | RECRUITING | PHASE3
540 Participants

A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-07-31
Completion: 2026-08-31
Conditions
Hot Flashes
Interventions
DRUG
No Results Yet
NCT06420245 | RECRUITING | NA
240 Participants

Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-31
Completion: 2026-11-30
Conditions
Diabetic Foot Ulcer
Interventions
DEVICE PROCEDURE
No Results Yet
NCT06415773 | COMPLETED | PHASE3
367 Participants

Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-06-04
Completion: 2025-06-13
Conditions
T2DM (Type 2 Diabetes Mellitus)
Interventions
DRUG
No Results Yet
NCT06411158 | RECRUITING | NA
216 Participants

Training for Urinary Leakage Improvement After Pregnancy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-12
Completion: 2027-05-12
Conditions
Urinary Incontinence Delivery Complication
Interventions
OTHER DEVICE
No Results Yet
NCT06392464 | COMPLETED
106 Participants

Validation of Naevia Medical in Valvulopathies

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-27
Completion: 2025-01-24
Conditions
Heart Valve Disease
Interventions
DEVICE
Results Available
NCT06389539 | RECRUITING | NA
220 Participants

Synbiotic to Attenuate Resorption of the Skeleton

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-12
Completion: 2028-04-30
Conditions
Osteoporosis Inflammation Aging
Interventions
OTHER
No Results Yet
NCT06366789 | RECRUITING | PHASE1
150 Participants

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-05-29
Completion: 2026-01-31
Conditions
AML With Gene Mutations
Interventions
DRUG
No Results Yet
NCT06362005 | COMPLETED | PHASE4
50 Participants

The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-05-01
Completion: 2025-07-01
Conditions
Lichen Planus, Oral
Interventions
DRUG
No Results Yet
NCT06359808 | RECRUITING
152 Participants

Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-04-01
Completion: 2026-06-30
Conditions
Colitis, Ulcerative Sleep Quality Gastrointestinal Microbiome Autonomic Nervous System Imbalance
No Results Yet
NCT06354673 | COMPLETED | NA
205 Participants

Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-04-04
Completion: 2025-09-04
Conditions
Paroxysmal Sympathetic Hyperactivity
Interventions
PROCEDURE DRUG
No Results Yet
NCT06352788 | RECRUITING | NA
35 Participants

From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-07-02
Completion: 2027-08-31
Conditions
Foot Injury
Interventions
DEVICE
No Results Yet
NCT06350006 | RECRUITING | PHASE1
924 Participants

SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-05-29
Completion: 2027-12-30
Conditions
CLDN18.2-positive Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06341712 | ACTIVE_NOT_RECRUITING | PHASE2
10 Participants

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-22
Completion: 2026-10-26
Conditions
Osteosarcoma Osteosarcoma in Children Osteosarcoma in Adolescents and Young Adults
Interventions
DRUG OTHER
No Results Yet
NCT06326047 | COMPLETED | PHASE2
299 Participants

A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-03-18
Completion: 2025-09-19
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
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