Clinical Trials
Showing trials with last updates posted in 2025.
156
Participants
Allograft vs. Autograft Nonunion
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-03-31
Completion:
2030-12-31
Conditions
Nonunion Fracture
Interventions
PROCEDURE
No Results Yet
44
Participants
Gemcitabine and Nab-Paclitaxel Combined With Iparomlimab and Tuvorilimab for Advanced Gallbladder Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-05-01
Completion:
2027-05-01
Conditions
Gallbladder Cancer Unresectable
Interventions
DRUG
No Results Yet
126
Participants
The Construction and Clinical Application of an Integrated Perioperative Management System for Lung Cancer Based on Wearable Devices and Intelligent Platforms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-01
Completion:
2026-12-01
Conditions
Non-Small Cell Lung Cancer (NSCLC)
Rehabilitation
Thoracic Surgery
Perioperative Management
Interventions
DEVICE
BEHAVIORAL
No Results Yet
80
Participants
Creatine and Perioperative Brain Health
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-01
Completion:
2027-12-31
Conditions
Neurocognitive Disorders
Postoperative Delirium
Interventions
DIETARY_SUPPLEMENT
No Results Yet
22
Participants
Neuro-Athletic Training Effects in Young Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-11-30
Completion:
2025-12-30
Conditions
Health Young Individuals
Physical Fitness
Interventions
BEHAVIORAL
No Results Yet
32
Participants
Yoga With and Without VR for Core, Balance, and Stress in University Students
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-06-19
Completion:
2026-01-30
Conditions
Health-Related Behavior
Interventions
OTHER
No Results Yet
600
Participants
Virtual Reality vs. Music Relaxation for Reducing Anxiety and Pain During Breast Biopsies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-06-30
Completion:
2027-06-30
Conditions
Breast Biopsy
Anxiety
Pain
Interventions
OTHER
No Results Yet
2083
Participants
Impact of Arterial Partial Pressure of Oxygen on Anastomotic Leakage After Esophagectomy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2021-01-01
Completion:
2025-12-01
Conditions
Esophageal Carcinoma
Esophageal Adenocarcinoma
Esophagectomy
PaO2
Esophageal Anastomotic Leakeage
No Results Yet
200
Participants
Assessment Of Difficult Airway Predictors: A Prospective Comparison Of Upper Airway Ultrasound And Conventional Anthropometric Measures
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-25
Completion:
2026-07-25
Conditions
Prediction of Difficult Airway
Difficult Airway Intubation
No Results Yet
25
Participants
Feasibility of Integrating Local Vibration Into Rehabilitation of Elderly Patients After Hip Fracture
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-11-19
Completion:
2026-11-19
Conditions
Fracture Femur
Elderly
Interventions
DIAGNOSTIC_TEST
DEVICE
OTHER
No Results Yet
28
Participants
Neoadjuvant SBRT Followed by Sintilimab Plus Chemotherapy for N3-Positive NSCLC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-31
Completion:
2027-10-31
Conditions
Locally Advanced Non-Small Cell Lung Cancer
Stage IIIb Non-small Cell Lung Cancer
Stage IIIC Non-Small Cell Lung Cancer
Interventions
DRUG
RADIATION
PROCEDURE
No Results Yet
114
Participants
Effect of Gimkit-Based Gamified Learning on Achievement Motivation, Academic Performance, and Game Experience in Respiratory Skills Training
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-05-06
Completion:
2025-05-06
Conditions
Gamified Learning
Gimkit
Game Based Learning
Nursing Students
Respiratory System Skills
Achievement Motivation
Academic Achievement
Gamification
Gamification in Health Education
Interventions
BEHAVIORAL
No Results Yet
120
Participants
Gait and Paraspinal sEMG in Degenerative Spinal Diseases
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-10
Completion:
2028-12-01
Conditions
Adult Spinal Deformity
Degenerative Scoliosis
Sagittal Deformity
Sagittal Imbalance
Coronal Vertical Axis
Lumbar Spinal Stenosis
Lumbar Disc Herniation
Cervical Spondylosis With Myelopathy
Interventions
OTHER
No Results Yet
3459
Participants
China Atrial Fibrillation With Complex Metabolic Disorder Cohort Study (CAME Cohort)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2026-02-01
Completion:
2036-02-01
Conditions
Atrial Fibrillation (AF)
Metabolic Disorders
No Results Yet
12
Participants
IASO208 Injection in the Treatment of Relapsed/Refractory B-cell Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-15
Completion:
2028-12-15
Conditions
Relapsed/Refractory B-cell Malignancies
Interventions
GENETIC
No Results Yet
100000
Participants
This Clinical Trial is a Retrospective, Multicenter Cohort Study Evaluating the Real-world Characteristics and Risk of Disease Recurrence in Hormone Receptor-positive, HER2-negative Early Breast Cancer.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-17
Completion:
2026-01-31
Conditions
Early Breast Cancer
No Results Yet
50
Participants
Effect of Ultrasound-Guided Dry Needling Targeting Rectus Capitus Posterior Major on Individuals With Headaches
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-02-01
Completion:
2026-06-01
Conditions
Headache Disorders, Primary
Headache, Cervicogenic
Interventions
OTHER
No Results Yet
119
Participants
Effect Of Education On Adherence, Self Care And Well-Being Of Patients With Chronic Kidney Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-03-03
Completion:
2021-10-29
Conditions
Chronic Kidney Disease (Stage 3-4)
Interventions
DEVICE
No Results Yet
374
Participants
Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-11-01
Completion:
2027-09-01
Conditions
Blood Transfusion
Hip Fracture Surgeries
Geriatric
Bleeding Complications
Bleeding as Surgical Complication (Treatment)
Bleeding
Blood Transfusions
Blood Transfusion Complication
Direct Oral Anticoagulants (DOACs)
No Results Yet
100
Participants
Improving Genetic Medicine for Ethnic Minority Groups
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-30
Completion:
2031-01-30
Conditions
Genetic Testing
No Results Yet
27
Participants
Study to Assess the Safety and Effectiveness of Beltaven® in Patients With Allergy to Apis Mellifera, Polistes Dominula or Vespula Spp.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-02-01
Completion:
2031-05-31
Conditions
Allergy
No Results Yet
50
Participants
Portrait Mobile Monitoring Solution V2.0 External Evaluation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-03-31
Completion:
2026-07-31
Conditions
Monitoring
Interventions
DEVICE
No Results Yet
27
Participants
Strengthening Exercises for Humeral Head Depressor Muscles
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-02
Completion:
2026-09-02
Conditions
Reverse Shoulder Arthroplasty
Depressor Muscle Training
Shoulder Rehabilitation
Interventions
OTHER
No Results Yet
574
Participants
Lung EIT Image Guide Ventilation in ARDS
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-20
Completion:
2028-12-20
Conditions
ARDS (Acute Respiratory Distress Syndrome)
Interventions
OTHER
BEHAVIORAL
No Results Yet
90
Participants
Trastuzumab Rezetecan in Advanced Solid Tumors Refractory to Standard Therapies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-18
Completion:
2027-09-11
Conditions
Urachal Cancer
Advanced Solid Tumor Cancer
Antibody-drug Conjugates
Interventions
DRUG
No Results Yet
30
Participants
Universal CAR-T Cell Injection Targeting CD19/BCMA in Patients With Inflammatory Bowel Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-20
Completion:
2027-12-30
Conditions
Moderate-to-severe Ulcerative Colitis
Crohn's Disease (CD)
Interventions
DRUG
No Results Yet
400
Participants
MPR for Stroke Risk Assessment of ICAS
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-01
Completion:
2027-12-15
Conditions
ICAS - Intracranial Atherosclerosis
Stroke Ischemic
Hemodynamic
Interventions
DRUG
No Results Yet
400
Participants
Digital Angiography-Derived Fractional Flow Assessment for Intracranial Stenosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-01
Completion:
2027-01-01
Conditions
Intracranial Atherosclerosis ICAS
Hemodynamic
Stroke
Interventions
DRUG
No Results Yet
106
Participants
Different Modalities for the Evaluation of Patients With Peri-menopausal Bleeding
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-01
Completion:
2026-08-31
Conditions
Perimenopausal Bleeding
Interventions
DIAGNOSTIC_TEST
No Results Yet
38
Participants
The Effects of Magnesium (Mg) Supplement and Alternate Maxillary Expansion and Constriction (Alt-RAMEC) in Patient With Transverse Maxillary Deficiency (TMD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-01
Completion:
2026-08-12
Conditions
Magnesium During Orthodontic Expansion
Orthodontic Patients Indicated for Maxillary Expansion
Interventions
DIETARY_SUPPLEMENT
No Results Yet
93
Participants
VR Therapy Effects in Lumbar Disc Herniation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2023-11-01
Completion:
2023-12-31
Conditions
Lumbar Disc Herniation
Interventions
OTHER
No Results Yet
70
Participants
Sucrase-Isomaltase (SI) Genes and Meal Load
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-02-01
Completion:
2028-02-01
Conditions
IBS - Irritable Bowel Syndrome
Sucrase-Isomaltase Deficiency
Interventions
DIETARY_SUPPLEMENT
No Results Yet
100
Participants
Hyaluronic Acid in the Treatment of Hyposalivation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-07-01
Completion:
2025-12-19
Conditions
Xerostomia Due to Hyposecretion of Salivary Gland
Interventions
COMBINATION_PRODUCT
No Results Yet
102
Participants
Regional Versus General Anesthesia for Hip Fracture and Postoperative Oxygenation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-11-27
Completion:
2026-12-31
Conditions
Hip-fracture
General Anaesthesia
Regional Anaesthesia
No Results Yet
10000
Participants
The Extended Study of Prevalence of Infection in Intensive Care IV
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2026-03-31
Completion:
2026-03-31
Conditions
Sepsis
Infection
No Results Yet
208
Participants
Pragmatic Geriatric Assessment Before CAR-T or Bispecific Antibody Therapy to Predict Side Effects and Outcomes in Older Patients (GA-ACT Trial)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-12
Completion:
2027-12-01
Conditions
Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma
CART Therapy
Bispecific Antibody
Geriatric Hematology
Interventions
OTHER
No Results Yet
24
Participants
Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-31
Completion:
2028-07-31
Conditions
LSD Reaction
Interventions
DRUG
No Results Yet
150
Participants
A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-18
Completion:
2029-03-31
Conditions
Non-Muscle Invasive Bladder Neoplasms
No Results Yet
350
Participants
Study of Bet v1 Antibodies Effect on Eye Allergy Symptoms in Adolescents and Adults With Birch Pollen Allergy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-19
Completion:
2027-02-28
Conditions
Allergic Conjunctivitis
Interventions
DRUG
No Results Yet
222
Participants
A Phase III Randomized Study of TACE Plus an Oral Triple-Agent Cocktail Versus TACE Plus First-Line Targeted Immunotherapy in Unresectable Hepatocellular Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-22
Completion:
2030-06-30
Conditions
Hepatocellular Carcinoma
Interventions
DRUG
DEVICE
No Results Yet
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