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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06908434 | RECRUITING | PHASE1
82 Participants

A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-06-10
Completion: 2027-12-31
Conditions
Solid Tumors Harboring a TP53 Y220C Mutation
Interventions
DRUG
No Results Yet
NCT06905197 | RECRUITING | PHASE1
70 Participants

A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-05-13
Completion: 2027-09-30
Conditions
Non Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06892314 | COMPLETED
80 Participants

Association Between CGM Metrics in Type 2 Diabetes Pregnancy and Perinatal Morbidity

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-05-15
Completion: 2025-11-26
Conditions
Type 2 Diabetes Mellitus (T2DM) Pregnancy
Interventions
BIOLOGICAL
No Results Yet
NCT06881992 | RECRUITING | PHASE3
16 Participants

A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-04-16
Completion: 2027-09-30
Conditions
Tumor Hyperinsulinism (Tumor HI)
Interventions
DRUG
No Results Yet
NCT06880744 | RECRUITING | PHASE3
530 Participants

A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-06-17
Completion: 2028-09-30
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT06880367 | RECRUITING | NA
56 Participants

Neuromodulatory Effects of Audio-proprio-phonatory Reinforcement Training on Subjective Tinnitus, Demonstrated by High-density Electroencephalogram (HD EEG)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-03-18
Completion: 2028-09-18
Conditions
Tinnitus, Subjective
Interventions
BEHAVIORAL DIAGNOSTIC_TEST
No Results Yet
NCT06872996 | RECRUITING | NA
100 Participants

Trophallergen Prick Tests (PT) : Influence of Food Sample Shelf Life on the Reproducibility of PT Results

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-04-10
Completion: 2027-10-10
Conditions
Food Allergy
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06847542 | RECRUITING | PHASE3
250 Participants

A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-27
Completion: 2028-09-12
Conditions
Neovascular Age-related Macular Degeneration
Interventions
DEVICE DRUG
No Results Yet
NCT06842316 | RECRUITING
100 Participants

Effects of Phytocannabinoids on Immune Response and Autophagy During Chronic Immune-mediated Inflammatory Diseases

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-04-10
Completion: 2027-04-09
Conditions
Inflammatory Disorder of Immune System Spondylitis, Ankylosing Arthritis, Rheumatoid Arthritis, Psoriatic Inflammatory Bowel Diseases Sjogren's Syndrome Lupus Erythematosus, Systemic
Interventions
OTHER
No Results Yet
NCT06840743 | COMPLETED | NA
180 Participants

Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-08-31
Completion: 2025-10-30
Conditions
Pain Thresholds
Interventions
OTHER
No Results Yet
NCT06838143 | RECRUITING
25 Participants

Ilaris NIS in Korea

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-03-29
Completion: 2028-09-30
Conditions
Hereditary Periodic Fever Syndromes Cryopyrin-associated Periodic Syndromes (CAPS) Colchicine Resistance Familial Mediterranean Fever (crFMF) TNF Receptor Associated Periodic Syndrome (TRAPS) Hyper-IgD Syndrome / Mevalonate Kinase Deficiency (HIDS/MKD) Systemic Juvenile Idiopathic Arthritis (sJIA)
Interventions
BIOLOGICAL
No Results Yet
NCT06835049 | RECRUITING | PHASE2
24 Participants

Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-27
Completion: 2028-03-31
Conditions
Sarcoma,Soft Tissue
Interventions
DRUG OTHER RADIATION PROCEDURE
No Results Yet
NCT06834113 | RECRUITING | NA
120 Participants

Impact of Pain From Injectables Antiretroviral Treatments in HIV-1 Patients Based on the Injection Site (Ventrogluteal or Dorsogluteal) and the Use or Non-use of Virtual Reality Headset

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-01-24
Completion: 2026-07-24
Conditions
HIV I Infection Injection Pain
Interventions
PROCEDURE
No Results Yet
NCT06833008 | RECRUITING | PHASE1/PHASE2
85 Participants

A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-03-14
Completion: 2028-10-03
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06824779 | ACTIVE_NOT_RECRUITING | PHASE4
30 Participants

Impact of FLU Vaccination on Nasal Resident Memory Immune Responses and Peripheral Respiratory-tropic Memory Immune Responses

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-05
Completion: 2025-12-19
Conditions
Volunteers Flu Vaccine
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT06824428 | COMPLETED
84 Participants

The Pain Perception Threshold in Attention Deficit Disorder With Hyperactivity

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-02-16
Completion: 2025-12-26
Conditions
Pain Threshold Attention Deficit Disorder With Hyperactivity (ADHD)
Interventions
OTHER
No Results Yet
NCT06817382 | RECRUITING | PHASE1
12 Participants

A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-22
Completion: 2028-01-31
Conditions
Duchenne Muscular Dystrophy
Interventions
GENETIC
No Results Yet
NCT06817018 | RECRUITING | PHASE2
80 Participants

Ginger Root Extract for Sciatic Pain Individuals

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-01
Completion: 2028-02-28
Conditions
Neuropathic Pain Sciatic Pain
Interventions
DIETARY_SUPPLEMENT DRUG
No Results Yet
NCT06813365 | RECRUITING | PHASE1
190 Participants

Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-06-12
Completion: 2026-12-30
Conditions
Nonsmall-cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06813248 | RECRUITING
100 Participants

Jigsaw Technique and Stroke Patient Care

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-15
Completion: 2025-01-17
Conditions
Nursing Education
No Results Yet
NCT06800352 | COMPLETED | NA
45 Participants

The Effect of Olive Oil and Centaury Oil on Rash

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-30
Completion: 2025-06-30
Conditions
Diaper Dermatitis
Interventions
OTHER
No Results Yet
NCT06798181 | RECRUITING
128 Participants

Neuropathic Pain and Type II Diabetic Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-15
Completion: 2025-06-15
Conditions
Neuropathic Pain Quality of Life Diabetic Neuropathies
No Results Yet
NCT06796426 | AVAILABLE

Treatment Protocol of Plozasiran in Adults and Adolescents With FCS

Study Type: EXPANDED_ACCESS
Last Updated: 2025-12-30
Conditions
Familial Chylomicronemia
Interventions
DRUG
No Results Yet
NCT06793397 | RECRUITING | PHASE3
330 Participants

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-10
Completion: 2027-03-18
Conditions
Major Depressive Disorder (MDD) Depression in Adults Depression - Major Depressive Disorder Depression Disorders Depression Disorder Depression
Interventions
DRUG BEHAVIORAL
No Results Yet
NCT06788886 | RECRUITING | NA
147 Participants

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-02-05
Completion: 2027-01-18
Conditions
Malignant Brain Neoplasm Malignant Solid Neoplasm Multiple Sclerosis Neuroendocrine Tumor Prostate Carcinoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT06785818 | RECRUITING
179 Participants

Long-term Follow up Local Registry Study of Kymriah in South Korea

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-03-12
Completion: 2039-12-30
Conditions
B-Cell Acute Lymphoblastic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma
Interventions
OTHER
No Results Yet
NCT06785779 | RECRUITING
77 Participants

Short-term Treatment Satisfaction in Hidradenitis Suppurativa Patients Initiated on Cosentyx in Routine Clinical Practice in Saudi Arabia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-03-10
Completion: 2026-09-30
Conditions
Hidradenitis Suppurativa (HS)
Interventions
OTHER
No Results Yet
NCT06781905 | RECRUITING
20 Participants

Description of Neurocognitive and Psychiatric Disorders Associated With Targeted Therapies Used in the Treatment of Lung Cancers With ALK/ROS1 Fusion and Their Impact on Patients' Quality of Life: Construction of an Experimental Patient-researcher Collaborative Care and Research Pathway

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-01-16
Completion: 2027-05-09
Conditions
Metastatic Lung Cancer Metastatic Lung Cancer With ALK/ROS1 Fusion
Interventions
OTHER
No Results Yet
NCT06778837 | COMPLETED
30 Participants

Lymphedema Sensor Technology Development Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-01-27
Completion: 2025-12-03
Conditions
Lymphedema Arm Lymphedema Cancer
Interventions
DEVICE
No Results Yet
NCT06761326 | COMPLETED | NA
80 Participants

Right Versus Left Distal Axillary Approach For Subclavian Vein Cannulation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-10-03
Completion: 2024-01-21
Conditions
Infraclavicular Vein Cannulation Venous Cannulation
Interventions
PROCEDURE
No Results Yet
NCT06757764 | RECRUITING | PHASE4
2340 Participants

The Effect and Safety of Combined Anti-platelet Treatment in Acute Ischemic Stroke Due to Large Artery Atherosclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-10
Completion: 2028-03-31
Conditions
Stenosis Artery Cerebral Infarction
Interventions
DRUG
No Results Yet
NCT06746220 | RECRUITING | NA
120 Participants

Effect of Physical Activity and/or Probiotics on Body Composition and Physiological Parameters in Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-09-16
Completion: 2027-09-15
Conditions
Healthy Women
Interventions
OTHER
No Results Yet
NCT06745921 | ACTIVE_NOT_RECRUITING | PHASE1
30 Participants

Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-02-24
Completion: 2026-10-01
Conditions
West Nile Viral Infection
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06744075 | ACTIVE_NOT_RECRUITING | NA
108 Participants

Study of the Clearance of Minimal Residual Disease Measured at the End of First-line Treatment in Patients With Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-24
Completion: 2027-12-20
Conditions
B-cell Lymphoma Hodgkin Lymphoma
Interventions
OTHER
No Results Yet
NCT06741683 | COMPLETED | PHASE2/PHASE3
187 Participants

A Study of Dengue Tetravalent Vaccine (TDV) in Healthy Participants in Japan

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-01-31
Completion: 2025-07-09
Conditions
Dengue Fever
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06725667 | COMPLETED | NA
50 Participants

Ultrasound-Guided Transversalis Fascia Plane Block Versus Caudal Block for Postoperative Analgesia in Children Undergoing Inguinal Herniorrhaphy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-11
Completion: 2025-12-06
Conditions
Ultrasound Transversalis Fascia Plane Block Caudal Block Postoperative Analgesia Children Inguinal Herniorrhaphy
Interventions
OTHER
No Results Yet
NCT06725602 | ENROLLING_BY_INVITATION | NA
40 Participants

Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-07
Completion: 2026-12-31
Conditions
Hemorrhage Hypovolemic Shock Tourniquets
Interventions
DEVICE
No Results Yet
NCT06724562 | RECRUITING
11 Participants

An Observational Pre-post Study to Observe if the Off Label Use of Anti-IL1 Therapies, Such as Anakinra or Canakinumab, Can Block ACVR1-induced Flare Activity and Heterotopic Ossification in FOP

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-04-01
Completion: 2027-03-31
Conditions
Fibrodysplasia Ossificans Progressiva (FOP)
Interventions
OTHER
No Results Yet
NCT06723041 | RECRUITING | NA
78 Participants

Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-11
Completion: 2026-12-31
Conditions
Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm
Interventions
PROCEDURE OTHER
No Results Yet
NCT06714825 | COMPLETED | PHASE1
39 Participants

Study of HS235 for Assessing the Pharmacokinetics, Safety, and Pharmacodynamics in Overweight/Obese Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-11-28
Completion: 2025-12-02
Conditions
Overweight and Obesity
Interventions
BIOLOGICAL DRUG
No Results Yet
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