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The Effect of Olive Oil and Centaury Oil on Rash

NCT ID: NCT06800352

Last Updated: 2025-12-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-30

Study Completion Date

2025-06-30

Brief Summary

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Diaper dermatitis is a preventable health problem. No study evaluating the efficacy of centaury oil in diaper dermatitis was found in the literature. This study will be conducted to investigate the effect of olive oil and centaury oil in the management of diaper dermatitis.

Detailed Description

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Diaper dermatitis is estimated to have an incidence of between 7% and 35%, although the prevalence cannot be determined precisely because it is not usually seen as a disease by parents and most patients are treated at home. Prevention of diaper dermatitis should be the main approach in treatment and care. Once it occurs, the aim of treatment is to accelerate the healing of the damaged area and prevent its spread. In the prevention and treatment of diaper dermatitis, practices such as ventilating the baby's diaper, changing the diaper frequently, keeping the area dry, cleaning with appropriate methods, using barrier creams and not tying the diaper tightly have been reported to be beneficial.

In the literature, studies using methods such as water, herbal cream (chamomile cream, calendula cream, aloe vera cream), barrier cream (zinc oxide) and herbal mixture (honey, beeswax, olive oil) were found in the treatment of infants with mild to moderate diaper dermatitis. It has been stated that the rates of diaper dermatitis will continue to increase if parents are not given adequate information about appropriate care and which products are beneficial or even harmful. In conclusion, diaper dermatitis is a preventable health problem. No study evaluating the efficacy of olive oil and centaury oil in diaper dermatitis was found in the literature. This study will be conducted to examine the effect of olive oil and centaury oil in the management of diaper dermatitis.

Conditions

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Diaper Dermatitis

Keywords

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olive oil centaury oil diaper dermatitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Block randomisation method will be used in this study. Using the online programme (http://www.randomizer.org), a random list of sets assigning infants to groups will be created. The infants who will constitute the sample of the study will be divided into 20 sets with 3 people in each set and sets will be formed by assigning numbers from 1 to 3 to each set. When the sets are obtained, the numbers from 1 to 3 will be written on small papers and group assignments will be made by lot method. In this way, the number of babies included in the groups and the probability of each baby to be included in the study groups will be equalised.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Olive Oil Application

The degree of diaper dermatitis will be evaluated before and after the procedure (72 hours after the first procedure) using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Infants'. After cleaning the perineum as described to the mothers, they will be asked to apply olive oil to the perineum four times a day, 1 cc each time.

Group Type EXPERIMENTAL

Control

Intervention Type OTHER

The degree of diaper dermatitis of the babies will be evaluated before and after the procedure (72 hours after the first procedure) by using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Babies (UNDDCS)'. Mothers will be asked to diaper their babies with cotton wool soaked with clear water.

Centaury Oil Application

The degree of diaper dermatitis of the infants will be evaluated before and after the procedure (72 hours after the first procedure) using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Infants'. After cleaning the perineum as described to the mothers, they will be asked to apply centaury oil to the perineum four times a day, 1 cc each time.

Group Type EXPERIMENTAL

Control

Intervention Type OTHER

The degree of diaper dermatitis of the babies will be evaluated before and after the procedure (72 hours after the first procedure) by using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Babies (UNDDCS)'. Mothers will be asked to diaper their babies with cotton wool soaked with clear water.

Interventions

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Control

The degree of diaper dermatitis of the babies will be evaluated before and after the procedure (72 hours after the first procedure) by using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Babies (UNDDCS)'. Mothers will be asked to diaper their babies with cotton wool soaked with clear water.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* The baby has mild diaper dermatitis according to the diaper dermatitis severity rating scale
* The baby receives antibiotic treatment
* The baby gets additional food
* The baby is between 6-18 months

Exclusion Criteria

* Infants with moderate or severe diaper dermatitis according to the diaper dermatitis severity rating scale
* Babies with open wounds on the perineum,
* Babies with any skin disease
* Babies who use barrier creams or special oils in routine care
Minimum Eligible Age

6 Months

Maximum Eligible Age

18 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Harran University

OTHER

Sponsor Role lead

Responsible Party

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HASRET YAĞMUR SEVİNÇ AKIN

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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H YAĞMUR SEVİNÇ AKIN, Assistant Professor

Role: STUDY_DIRECTOR

Harran University

MAKSUDE YILDIRIM, Assistant Professor

Role: PRINCIPAL_INVESTIGATOR

Adiyaman University

BARIŞ AKIN, Specialist nurse

Role: PRINCIPAL_INVESTIGATOR

Mardin Training and Research Hospital

NESRİN ŞEN CELASİN, Assoc. Professor

Role: PRINCIPAL_INVESTIGATOR

Celal Bayar University

ZÜLEYHA GÜRDAP, RESEARCH ASSISTANT

Role: PRINCIPAL_INVESTIGATOR

Inonu University

Locations

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Mardin Training and Research Hospital

Mardin, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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HRU-VSYO-HYSA-2024/139

Identifier Type: -

Identifier Source: org_study_id