Clinical Trials

Showing trials with last updates posted in 2025.

NCT05957081 | RECRUITING | PHASE1
67 Participants

Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-01-03
Completion: 2029-10-30
Conditions
Advanced or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
NCT05953012 | COMPLETED | PHASE1
17 Participants

Study to Assess Safety and Tolerability of PMC-403 in Subjects With Neovascular Age-related Macular Degeneration

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-07-20
Completion: 2025-08-22
Conditions
Neovascular Age-related Macular Degeneration
Interventions
DRUG
No Results Yet
NCT05919160 | ENROLLING_BY_INVITATION | NA
10 Participants

A High-density Microelectrode for Human Neuronal Recordings

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-01
Completion: 2026-12-31
Conditions
Parkinson Disease, Idiopathic
Interventions
DEVICE
No Results Yet
NCT05913180 | RECRUITING | PHASE2
180 Participants

Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-09-19
Completion: 2026-08-15
Conditions
Catheter-Associated Urinary Tract Infection
Interventions
DRUG
No Results Yet
NCT05908162 | COMPLETED
185 Participants

Algorithm for Predicting the Unfavorable Course of Sepsis in Children

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2021-07-01
Completion: 2024-12-25
Conditions
Sepsis
Interventions
DIAGNOSTIC_TEST
NCT05898854 | COMPLETED | PHASE2
20 Participants

[68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-02-15
Completion: 2025-12-18
Conditions
Gastric Cancer Gastro Esophageal Junctional Cancer Cancer
Interventions
DRUG
No Results Yet
NCT05887193 | COMPLETED | NA
14 Participants

Effects of Contemporary Cycling Saddle Designs on Penile Transcutaneus Oxygen and Carbon Dioxide Levels in Elite Road Cyclists Riding on a Stationary Trainer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-04-21
Completion: 2023-05-14
Conditions
Healthy Cyclists Blood Gas Monitoring, Transcutaneous Penile Numbness
Interventions
DEVICE
No Results Yet
NCT05879250 | RECRUITING | PHASE2
39 Participants

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-05-22
Completion: 2027-12-27
Conditions
Glioblastoma, IDH-Wildtype MGMT-Unmethylated Glioblastoma
Interventions
PROCEDURE RADIATION DRUG
No Results Yet
NCT05869487 | RECRUITING | NA
298 Participants

Calf Circumference Versus X-ray Absorptiometry in the Diagnosis of Sarcopenia in Elderly Hospitalized Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-12-11
Completion: 2027-04-11
Conditions
Sarcopenia
Interventions
RADIATION
No Results Yet
NCT05863351 | RECRUITING | PHASE3
472 Participants

Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-09-07
Completion: 2030-12-01
Conditions
Metastatic Renal Cell Carcinoma Stage IV Renal Cell Cancer AJCC v8
Interventions
PROCEDURE OTHER
No Results Yet
NCT05846516 | RECRUITING | PHASE1
171 Participants

A Study to Test KISIMA-02 Vaccine-based Immunotherapy and Ezabenlimab in People With Pancreatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-05-25
Completion: 2029-02-15
Conditions
Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT05840159 | RECRUITING | PHASE4
664 Participants

A Study of Doxycycline to Treat Chlamydial Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-01-19
Completion: 2026-02-28
Conditions
Chlamydial Infection
Interventions
DRUG OTHER
No Results Yet
NCT05839379 | RECRUITING
350 Participants

Targeted Pediatric High-Grade Glioma Therapy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-08-02
Completion: 2029-08-28
Conditions
High Grade Glioma Diffuse Intrinsic Pontine Glioma Anaplastic Astrocytoma Glioblastoma Glioblastoma Multiforme Diffuse Midline Glioma, H3 K27M-Mutant Metastatic Brain Tumor WHO Grade III Glioma WHO Grade IV Glioma
No Results Yet
NCT05834244 | RECRUITING | PHASE1
32 Participants

A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-10-26
Completion: 2026-06-30
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT05831085 | RECRUITING | NA
1500 Participants

Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-06-14
Completion: 2027-06-30
Conditions
Coronary Artery Stenosis
Interventions
PROCEDURE
No Results Yet
NCT05815173 | RECRUITING | PHASE1
40 Participants

Ladarixin With Sotorasib in Advanced NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-08-01
Completion: 2027-08-31
Conditions
Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation
Interventions
DRUG
No Results Yet
NCT05815160 | ACTIVE_NOT_RECRUITING | PHASE1
34 Participants

Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-05-02
Completion: 2026-01-31
Conditions
Small Cell Lung Cancer Recurrent
Interventions
DRUG
No Results Yet
NCT05810220 | RECRUITING | NA
200 Participants

Investigating Auditory Processing in the Users of Auditory Brainstem and Cochlear Implants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2018-12-02
Completion: 2026-12-31
Conditions
Deafness
Interventions
DEVICE
No Results Yet
NCT05798117 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
21 Participants

An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-02-28
Completion: 2026-09-09
Conditions
Systemic Lupus Erythematosus Lupus Nephritis
Interventions
DRUG
No Results Yet
NCT05795569 | COMPLETED | NA
112 Participants

Removal of Nasogastric Feeding Tube Post Extubation in ICU : a Prospective Randomized Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-03-21
Completion: 2025-04-10
Conditions
Deglutition Disorders Intensive Care Unit Syndrome Swallowing Disorder Feeding or Eating Disorder
Interventions
PROCEDURE DIAGNOSTIC_TEST
No Results Yet
NCT05776888 | ACTIVE_NOT_RECRUITING
106 Participants

Early Versus Late Ofatumumab (Kesimpta®) Use in Austrian RMS-Patients Over 2 Years

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2023-07-10
Completion: 2026-08-31
Conditions
Relapsing Multiple Sclerosis
Interventions
OTHER
No Results Yet
NCT05766371 | RECRUITING | PHASE2
48 Participants

Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-12-15
Completion: 2027-05-31
Conditions
Castrate Resistant Prostate Cancer Metastatic Castration-resistant Prostate Cancer Prostate Cancer Prostate Carcinoma
Interventions
DRUG
No Results Yet
NCT05766124 | RECRUITING | PHASE2/PHASE3
30 Participants

Trial of Reduced Alteplase Dose for Parapneumonic Effusion (TRAPPE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-11-01
Completion: 2028-03-31
Conditions
Pleural Infection
Interventions
DRUG
No Results Yet
NCT05755386 | RECRUITING | PHASE3
106 Participants

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-10-02
Completion: 2028-10-27
Conditions
IC-MPGN
Interventions
DRUG
No Results Yet
NCT05752695 | ENROLLING_BY_INVITATION
200 Participants

Operation Korsband

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2023-09-01
Completion: 2028-12-31
Conditions
Anterior Cruciate Ligament Injuries
No Results Yet
NCT05746169 | TERMINATED
1576 Participants

Discovering Cancer Risks From Environmental Contaminants and Maternal/Child Health

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2021-09-01
Completion: 2025-07-21
Conditions
Cancer
Interventions
OTHER
No Results Yet
NCT05740371 | COMPLETED | PHASE4
50 Participants

Safety of Argatroban Infusion in Conduction Disturbances

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-04-18
Completion: 2021-05-06
Conditions
Stable Coronary Artery Disease (CAD) Unstable Angina (Troponin Negative)
Interventions
DRUG
NCT05735314 | RECRUITING | NA
450 Participants

A New Combination of Evidence-Based Interventions to Improve Primary Care Diagnostic Safety and Efficiency

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-01-08
Completion: 2026-07-16
Conditions
Anemia Decreased Glomerular Filtration Rate
Interventions
OTHER
No Results Yet
NCT05733767 | RECRUITING | PHASE2
424 Participants

Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-11-03
Completion: 2027-08-28
Conditions
Cardiopulmonary Disease Smoking Cessation Inpatient
Interventions
OTHER
No Results Yet
NCT05721989 | COMPLETED | PHASE1
267 Participants

A Research Study Looking Into Blood Levels of Three Different Formulations of the Study Medicine Ziltivekimab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-02-03
Completion: 2024-01-08
Conditions
Healthy Participants
Interventions
DRUG
No Results Yet
NCT05708235 | RECRUITING | PHASE2
1260 Participants

A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-04-01
Completion: 2028-12-30
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT05701657 | RECRUITING | NA
8000 Participants

Nutrition for Precision Health, Powered by the All of Us

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-04-14
Completion: 2026-12-31
Conditions
Nutrition Health Dietary Habits
Interventions
OTHER
No Results Yet
NCT05695937 | COMPLETED | NA
58 Participants

Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Patients With Familial Hypercholesterolemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-05-22
Completion: 2023-12-29
Conditions
Familial Hypercholesterolemia
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT05691244 | RECRUITING | PHASE3
514 Participants

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-24
Completion: 2026-09-30
Conditions
Acute Ischemic Stroke Cerebral Stroke
Interventions
DRUG
No Results Yet
NCT05689710 | SUSPENDED | NA
30 Participants

The Effects of Inositol on Glucose Metabolism in Patients With Metabolic Syndrome at Risk of Cardiac Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-12-23
Completion: 2026-01-31
Conditions
Metabolic Syndrome Cardiac Fibrosis
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT05685238 | ACTIVE_NOT_RECRUITING | PHASE3
451 Participants

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A (FRONTIER 4)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-02-13
Completion: 2028-06-30
Conditions
Haemophilia A Haemophilia A With Inhibitors
Interventions
DRUG
No Results Yet
NCT05678530 | RECRUITING
1000 Participants

Observational, Non-Interventional Study Supporting Validation of VO2Max Estimation Methods Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2019-06-06
Completion: 2027-03-31
Conditions
Cardiopulmonary
No Results Yet
NCT05673005 | COMPLETED | NA
20 Participants

MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-04-01
Completion: 2024-07-24
Conditions
Erectile Dysfunction Following Radical Prostatectomy
Interventions
DEVICE
NCT05650632 | RECRUITING | PHASE1
180 Participants

A Study to Assess Adverse Events of Intravenously (IV) Infused ABBV-383 in Adult Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-03-21
Completion: 2029-08-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05642533 | COMPLETED
1061 Participants

Obesity and Cardiovascular Diseases, Cross-sectional Study in Saudi Arabia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2022-12-31
Completion: 2023-09-14
Conditions
Obesity and Cardiovascular Risk
Interventions
OTHER
No Results Yet
Previous
Sorted by latest updates
Next
Showing 40 trials per page