Discovering Cancer Risks From Environmental Contaminants and Maternal/Child Health
NCT ID: NCT05746169
Last Updated: 2025-12-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
1576 participants
OBSERVATIONAL
2021-09-01
2025-07-21
Brief Summary
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Detailed Description
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The study team will collect questionnaire data and biospecimen samples starting at the second trimester of pregnancy up until the child reaches four years of age. A Cohort Ambassador Program will also be established to invite participants across our three sites to provide continuous feedback which will be integrated into the research priorities.
Conditions
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Keywords
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Pregnant women and their children
The DREAM cohort will recruit from University of California, San Francisco (UCSF) Mission Bay, Zuckerberg San Francisco General Hospital, and Fresno Community Medical Center locations to enroll an economically, geographically, ethnically and racially diverse cohort of pregnant women and their children for long term follow-up.
Health Questionnaires
A questionnaire with content developed and tested in the investigator's previous reproductive and cancer epidemiology studies as part of the NIH Environmental Influences on Child Health Outcomes (ECHO) consortium will be used to collect information on primary established and hypothesized risk factors for cancer and additional covariates.
Specimen sample collection
Collection of blood, urine, nails, hair, and saliva samples will be obtained during the participant encounters.
Interventions
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Health Questionnaires
A questionnaire with content developed and tested in the investigator's previous reproductive and cancer epidemiology studies as part of the NIH Environmental Influences on Child Health Outcomes (ECHO) consortium will be used to collect information on primary established and hypothesized risk factors for cancer and additional covariates.
Specimen sample collection
Collection of blood, urine, nails, hair, and saliva samples will be obtained during the participant encounters.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* English or Spanish-speaking.
* Children born of participants enrolled during pregnancy will be enrolled in the DREAM cohort.
* Inclusion criterion for the DREAM Cohort Ambassador Program is limited to research participants in the DREAM Cohort.
Exclusion Criteria
* Women expecting the birth of multiples (twins, triplets, etc.).
18 Years
ALL
Yes
Sponsors
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National Cancer Institute (NCI)
NIH
California Office of Environmental Health Hazard Assessment (OEHHA)
UNKNOWN
University of California, San Francisco
OTHER
Responsible Party
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Principal Investigators
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Peggy Reynolds, PhD
Role: PRINCIPAL_INVESTIGATOR
University of California, San Francisco
Locations
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University of California, Berkeley
Berkeley, California, United States
Fresno Community Regional Medical Center
Fresno, California, United States
University of California, San Francisco
San Francisco, California, United States
Countries
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Other Identifiers
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NCI-2022-10633
Identifier Type: REGISTRY
Identifier Source: secondary_id
21621
Identifier Type: -
Identifier Source: org_study_id