A New Combination of Evidence-Based Interventions to Improve Primary Care Diagnostic Safety and Efficiency
NCT ID: NCT05735314
Last Updated: 2025-12-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
450 participants
INTERVENTIONAL
2024-01-08
2026-07-16
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
HEALTH_SERVICES_RESEARCH
NONE
Study Groups
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Experimental: Step 1 (3 clinics) - 24 months of intervention
Enhanced diagnostic team implementing three evidence-based interventions
we designed an enhanced team process entailing: 1) using automated abnormal test result detection and tracking; 2) expanding the primary care team to include CPs to guide the evaluation of anemia to identify underlying causes; and 3) using NNs to engage patients in the healthcare team and diagnostic process and increase patient activation.
Usual care
Usual care involves primary care physicians ordering additional tests and referrals to evaluate patients with new anemia and decreased glomerular filtration rate (GFR) .
Experimental: Step 2 (3 clinics) - 1 month of control followed by 18 months of intervention
Enhanced diagnostic team implementing three evidence-based interventions
we designed an enhanced team process entailing: 1) using automated abnormal test result detection and tracking; 2) expanding the primary care team to include CPs to guide the evaluation of anemia to identify underlying causes; and 3) using NNs to engage patients in the healthcare team and diagnostic process and increase patient activation.
Usual care
Usual care involves primary care physicians ordering additional tests and referrals to evaluate patients with new anemia and decreased glomerular filtration rate (GFR) .
Experimental: Step 3 (3 clinics) - 2 months control followed by 12 months of intervention
Enhanced diagnostic team implementing three evidence-based interventions
we designed an enhanced team process entailing: 1) using automated abnormal test result detection and tracking; 2) expanding the primary care team to include CPs to guide the evaluation of anemia to identify underlying causes; and 3) using NNs to engage patients in the healthcare team and diagnostic process and increase patient activation.
Usual care
Usual care involves primary care physicians ordering additional tests and referrals to evaluate patients with new anemia and decreased glomerular filtration rate (GFR) .
Experimental: Step 4 (4 clinics) - 2 months control followed by 12 months of intervention
Enhanced diagnostic team implementing three evidence-based interventions
we designed an enhanced team process entailing: 1) using automated abnormal test result detection and tracking; 2) expanding the primary care team to include CPs to guide the evaluation of anemia to identify underlying causes; and 3) using NNs to engage patients in the healthcare team and diagnostic process and increase patient activation.
Usual care
Usual care involves primary care physicians ordering additional tests and referrals to evaluate patients with new anemia and decreased glomerular filtration rate (GFR) .
Interventions
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Enhanced diagnostic team implementing three evidence-based interventions
we designed an enhanced team process entailing: 1) using automated abnormal test result detection and tracking; 2) expanding the primary care team to include CPs to guide the evaluation of anemia to identify underlying causes; and 3) using NNs to engage patients in the healthcare team and diagnostic process and increase patient activation.
Usual care
Usual care involves primary care physicians ordering additional tests and referrals to evaluate patients with new anemia and decreased glomerular filtration rate (GFR) .
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* agree to participate.
* hemoglobin result \< 10.8 for females and \< 12.5 for males with normal white cell count and platelet count (the prior hemoglobin results must have been in normal range, with a look-back period of two years)
* an eGFR value \< 60 (the prior eGFR results must have been in normal range, with a look-back range of two years)
* the matching creatinine results must also be in normal range
* not pregnant
* speak English or Spanish.
18 Years
ALL
No
Sponsors
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The University of Texas Health Science Center, Houston
OTHER
Responsible Party
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Eric Thomas
Professor
Principal Investigators
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Eric Thomas, MD,MPH
Role: PRINCIPAL_INVESTIGATOR
The University of Texas Health Science Center, Houston
Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, United States
Countries
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Central Contacts
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Facility Contacts
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Eric Thomas, MD, MPH
Role: primary
Eric Thomas
Role: backup
Other Identifiers
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HSC-MS-22-0815
Identifier Type: -
Identifier Source: org_study_id