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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06661122 | RECRUITING
100 Participants

A Study to Learn About How Safe Darolutamide is and How Well it Works in Combination With Androgen Deprivation Therapy and Docetaxel in Routine Medical Care for Japanese Men With Low Volume Metastatic Hormone-Sensitive Prostate Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-11-18
Completion: 2031-03-31
Conditions
Metastatic Hormone-sensitive Prostate Cancer (mHSPC) Low-volume Metastasis
Interventions
DRUG
No Results Yet
NCT06659341 | RECRUITING | PHASE1
104 Participants

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-11-08
Completion: 2027-07-31
Conditions
Advanced Solid Tumors Harboring KRAS G12C Mutation
Interventions
DRUG
No Results Yet
NCT06656884 | RECRUITING
500 Participants

FARAPULSE Workflow Assessment Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-06
Completion: 2026-02-15
Conditions
Atrial Fibrillation (AF)
No Results Yet
NCT06648915 | ACTIVE_NOT_RECRUITING
364 Participants

Lipoprotein(a) and Progression of Aortic Stenosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-02-10
Completion: 2026-02-28
Conditions
Aortic Valve Stenosis Lipoprotein(a)
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06645808 | RECRUITING | EARLY_PHASE1
32 Participants

PET-imaging of Two Vartumabs in Patients With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-12-10
Completion: 2026-08-31
Conditions
Solid Tumor Colon Carcinoma Rectal Carcinoma Osteosarcoma Chondrosarcoma Lung Carcinoma Head and Neck Squamous Cell Carcinoma Esophageal Carcinoma Gastric Carcinoma Pancreas Carcinoma Bladder Carcinoma Glioblastoma Soft Tissue Sarcoma (STS) Breast Cancer
Interventions
BIOLOGICAL RADIATION
No Results Yet
NCT06640894 | RECRUITING | NA
66 Participants

Power2Walk: The Impact of Functional Power Training on Participation and Activity in Children With Cerebral Palsy.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-19
Completion: 2027-08-31
Conditions
Cerebral Palsy, Spastic
Interventions
OTHER
No Results Yet
NCT06629649 | RECRUITING | NA
1800 Participants

Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-22
Completion: 2029-09-29
Conditions
Glaucoma Ocular Hypertension
Interventions
OTHER
No Results Yet
NCT06628310 | RECRUITING | PHASE2
180 Participants

A Study to Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-12-13
Completion: 2030-10-31
Conditions
Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Esophageal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06626659 | COMPLETED
40 Participants

Lipoprotein (a) and Vascular Regenerative Cell Content

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-05
Completion: 2024-12-03
Conditions
Cardiovascular Diseases Atherosclerosis Cardiovascular Disease Ischemic Heart Disease Dyslipidemia
No Results Yet
NCT06625541 | COMPLETED | PHASE1
57 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AJ302-IM in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-06-24
Completion: 2025-08-15
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06623630 | RECRUITING | PHASE1
12 Participants

Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-12-04
Completion: 2026-04-30
Conditions
Multiple Myeloma
Interventions
DRUG RADIATION
No Results Yet
NCT06614270 | RECRUITING | NA
15 Participants

Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-01-06
Completion: 2026-01-06
Conditions
Systemic Sclerosis (SSc) ANCA Associated Vasculitis (AAV) Idiopathic Inflammatory Myopathy (IIM) Sjogren's Syndrome Antiphospholipid Syndrome Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT06603181 | COMPLETED | NA
60 Participants

Effect of Extracorporeal Shock Wave Therapy (ESWT) and Phonophoresis Treatment in Patients With Lateral Epicondylitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-09-25
Completion: 2025-01-30
Conditions
Lateral Epicondylitis Extracorporeal Shock Wave Therapy Phonophoresis
Interventions
OTHER
No Results Yet
NCT06602037 | RECRUITING | NA
90 Participants

ImmunoPET Imaging of Pancreatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-11-20
Completion: 2027-06-30
Conditions
Neoplasms Pancreatic
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06591429 | RECRUITING
25 Participants

Smoldering Inflammation in MS

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-06-19
Completion: 2027-06-30
Conditions
Multiple Sclerosis
Interventions
RADIATION DRUG
No Results Yet
NCT06588205 | RECRUITING
200 Participants

Exploring the Clinical Impact of MYC Aberrations and Their Relationship With Microenvironment in Diffuse Large B Cell Lymphoma and High-Grade B Cell Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-05
Completion: 2027-12-31
Conditions
Diffuse Large B Cell Lymphoma High-grade B-cell Lymphoma High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
No Results Yet
NCT06587386 | COMPLETED | PHASE4
55 Participants

The Minimum Effective Dose (ED90) of Liposomal Bupivacaine for Preserving Motor Function

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-20
Completion: 2025-11-10
Conditions
Motion Sickness
Interventions
DRUG
No Results Yet
NCT06581627 | COMPLETED | PHASE1
24 Participants

A Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-26
Completion: 2024-10-31
Conditions
Healthy Volunteers Sickle Cell Disease Thalassemia
Interventions
DRUG
No Results Yet
NCT06581328 | RECRUITING | PHASE4
400 Participants

A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-03-27
Completion: 2027-10-01
Conditions
Ulcerative Colitis Crohn's Disease
Interventions
DRUG
No Results Yet
NCT06581263 | RECRUITING
15 Participants

Psychedelic Virtual Reality

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-22
Completion: 2026-03-22
Conditions
Psychedelic Experiences Virtual Reality Healthy Volunteer
Interventions
DEVICE
No Results Yet
NCT06562673 | COMPLETED | PHASE1/PHASE2
10 Participants

Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-12-03
Completion: 2025-04-17
Conditions
Osteosarcoma Bone Cancer
Interventions
DRUG
No Results Yet
NCT06559371 | RECRUITING
150 Participants

68Ga FAPI PET/CT Evaluation of Axillary Lymph Node Status After Neoadjuvant Therapy in Patients With Clinical Axillary Lymph Node Positive Breast Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-30
Completion: 2026-06-30
Conditions
BREAST CANCER PET/CT
No Results Yet
NCT06549699 | COMPLETED | NA
206 Participants

Medically Used Tailored Traditional Food to Optimize Nutrition in Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-12
Completion: 2025-11-11
Conditions
Heart Failure
Interventions
OTHER
No Results Yet
NCT06542874 | COMPLETED | PHASE2
448 Participants

A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-07
Completion: 2025-10-01
Conditions
Type 2 Diabetes (T2D)
Interventions
DRUG
No Results Yet
NCT06535659 | RECRUITING
122 Participants

VitaFlow LIBERTY Europe

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-05-06
Completion: 2027-06-06
Conditions
Aortic Valve Stenosis
Interventions
DEVICE
No Results Yet
NCT06534723 | RECRUITING | PHASE3
570 Participants

Phase 3 Clinical Trial of Wujia Yizhi Granules in the Treatment of Mild-to-moderate Alzheimer's Dementia (Syndrome of Deficiency of Spleen and Kidney)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-20
Completion: 2026-08-31
Conditions
Alzheimer's Dementia
Interventions
DRUG
No Results Yet
NCT06526546 | ACTIVE_NOT_RECRUITING
356 Participants

ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-31
Completion: 2026-02-28
Conditions
Paroxysmal Atrial Fibrillation
No Results Yet
NCT06525532 | RECRUITING
35 Participants

Clinical-MRI Evaluation in Patients Undergoing Subtalar Arthrorisis With Reabsorbable Endorthesis Implant in PLLA

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-06-12
Completion: 2026-11-30
Conditions
Lower Limb Deformity
Interventions
OTHER
No Results Yet
NCT06522932 | RECRUITING | PHASE1
32 Participants

PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-23
Completion: 2027-01-31
Conditions
Non Hodgkin Lymphoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT06516874 | RECRUITING | NA
13 Participants

A Pilot Study of Trauma-Focused Cognitive-Behavioral Therapy for Treatment of Post-traumatic Stress in Adults.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-22
Completion: 2026-02-28
Conditions
Post Traumatic Stress Disorder Complex Post-Traumatic Stress Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06510998 | RECRUITING | NA
390 Participants

Isometric Resistance Exercise for Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-01-01
Completion: 2027-07-28
Conditions
Hypertension
Interventions
BEHAVIORAL
No Results Yet
NCT06494189 | COMPLETED | PHASE1
9 Participants

Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-31
Completion: 2025-04-10
Conditions
Head and Neck Cancer
Interventions
BIOLOGICAL DRUG RADIATION
No Results Yet
NCT06492434 | COMPLETED | NA
16 Participants

Enhancing Community Participation Through Peer-Delivered Decision Support

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-01
Completion: 2025-08-31
Conditions
Severe Mental Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06475989 | RECRUITING | PHASE3
264 Participants

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-22
Completion: 2030-09-30
Conditions
Refractory Differentiated Thyroid Gland Carcinoma
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT06475235 | RECRUITING | PHASE1
15 Participants

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-18
Completion: 2025-12-30
Conditions
Lymphoma Primary Central Nervous System Lymphoma
Interventions
DRUG
No Results Yet
NCT06470815 | ENROLLING_BY_INVITATION
400 Participants

ROADSTER 3 Extended Follow-up Sub-Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-31
Completion: 2029-07-31
Conditions
Carotid Artery Diseases
Interventions
PROCEDURE
No Results Yet
NCT06461897 | RECRUITING | PHASE3
675 Participants

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-08-19
Completion: 2030-07-31
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06446661 | NOT_YET_RECRUITING | NA
38 Participants

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-15
Completion: 2027-06-15
Conditions
Acute Lymphoblastic Leukemia
Interventions
OTHER
No Results Yet
NCT06442930 | RECRUITING
3000 Participants

EXtubation Related Complications - the EXTUBE Study (EXTUBE)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-04-14
Completion: 2026-12-31
Conditions
Extubation
No Results Yet
NCT06431815 | ACTIVE_NOT_RECRUITING
228 Participants

ADVENT Post Approval Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-09-25
Completion: 2028-10-31
Conditions
Paroxysmal Atrial Fibrillation
Interventions
DEVICE
No Results Yet
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