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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06092671 | RECRUITING | NA
444 Participants

Effect of FPCA on Incidence of Emergency Delirium in Children After Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-10-24
Completion: 2026-09-30
Conditions
Postoperative Complications Child Family Emergence Delirium General Anaesthesia Perioperative Care
Interventions
OTHER
No Results Yet
NCT06076538 | RECRUITING
97 Participants

PET/MR for Characterization of Renal Masses (RMs)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2023-08-01
Completion: 2028-06-01
Conditions
Renal Tumor Renal Cell Carcinoma Renal Tumor, Benign
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06045754 | RECRUITING | PHASE4
100 Participants

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-04-18
Completion: 2027-06-28
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
NCT06042478 | ACTIVE_NOT_RECRUITING | PHASE3
471 Participants

Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-11-15
Completion: 2025-09-17
Conditions
Chronic Spontaneous Urticaria
Interventions
DRUG
No Results Yet
NCT06038318 | RECRUITING | NA
325 Participants

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-10-16
Completion: 2026-12-31
Conditions
Stress Anxiety
Interventions
BEHAVIORAL
No Results Yet
NCT06035094 | ACTIVE_NOT_RECRUITING | NA
30 Participants

An Exercise Intervention to Improve Overall Brain Health

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-01-23
Completion: 2026-01-12
Conditions
Brain Care Score Exercise Hypertension BMI
Interventions
BEHAVIORAL
No Results Yet
NCT06034327 | RECRUITING | NA
150 Participants

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-09-18
Completion: 2027-01-31
Conditions
Myopia Juvenile Myopia Myopia Progression
Interventions
DEVICE
No Results Yet
NCT06028022 | RECRUITING | PHASE2
80 Participants

Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase Inhibitors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-10-18
Completion: 2026-10-16
Conditions
Estrogen Receptor-Positive Breast Carcinoma
Interventions
DIETARY_SUPPLEMENT DRUG OTHER
No Results Yet
NCT06027307 | ACTIVE_NOT_RECRUITING | PHASE3
541 Participants

Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-10-25
Completion: 2027-06-30
Conditions
Tricuspid Regurgitation Heart Failure With Preserved Ejection Fraction
Interventions
DRUG
No Results Yet
NCT06016088 | RECRUITING | PHASE1/PHASE2
72 Participants

A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-04-01
Completion: 2026-04-30
Conditions
Cystic Fibrosis Lung Respiratory Infections, Recurrent, Chronic Pseudomonas Aeruginosa
Interventions
DRUG
No Results Yet
NCT06013176 | COMPLETED | NA
476 Participants

Behavioral Economic Strategies to Improve PRO Adherence

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-12-04
Completion: 2024-06-04
Conditions
Cancer
Interventions
OTHER
Results Available
NCT06011759 | COMPLETED | NA
4 Participants

Maintaining Implementation Through Dynamic Adaptations (MIDAS) Suicide Prevention 2.0 Clinical Telehealth

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2022-11-01
Completion: 2024-08-29
Conditions
Suicidal Self-directed Violence Suicidal Preparatory Behavior
Interventions
BEHAVIORAL
Results Available
NCT06008691 | RECRUITING
1500 Participants

A Prospective, Observational Cohort Study on the Clinical Impact of Novel Monoclonal Antibodies in B-cell Non-Hodgkin Lymphoma in Italian Clinical Practice

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2023-12-27
Completion: 2038-10-31
Conditions
Non-Hodgkin Lymphoma, B-cell
Interventions
DRUG
No Results Yet
NCT05999877 | ACTIVE_NOT_RECRUITING
192 Participants

PICAROS - Acalabrutinib RWE on 1L CLL in Spain

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2023-07-11
Completion: 2026-12-31
Conditions
Chronic Lymphocytic Leukemia
No Results Yet
NCT05993481 | ENROLLING_BY_INVITATION | NA
640 Participants

The Noninvasive Blood Pressure Measurement Effect on the Hypotension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-25
Completion: 2026-11-25
Conditions
Hypotension During Surgery
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05983887 | COMPLETED | NA
12 Participants

The Effect of Therapeutic Climbing on Muscle Strength, Tone and Balance in Hemiplegic Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-04-10
Completion: 2023-08-31
Conditions
Hemiplegia and Hemiparesis
Interventions
OTHER
No Results Yet
NCT05945823 | ACTIVE_NOT_RECRUITING | PHASE2
53 Participants

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-07-13
Completion: 2026-03-31
Conditions
Siewert Type 1 GEJ Cancer Pancreatic Cancer Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal Cancer Esophageal Adenocarcinoma Esophageal Squamous Cell Cancer
Interventions
DRUG
No Results Yet
NCT05944861 | COMPLETED | NA
38 Participants

Combination of Fluoroscopy and Ultrasonography Guidance in Sacroiliac Joint Injections

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-02-15
Completion: 2024-01-15
Conditions
Sacroiliac Joint Somatic Dysfunction Sacroiliac Joint Pain
Interventions
OTHER
No Results Yet
NCT05935514 | COMPLETED | NA
152 Participants

Improving Glycemic Control Using a Virtual Weight Control Program and Continuous Glucose Monitoring

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-08-22
Completion: 2025-10-23
Conditions
Diabetes Mellitus Type 2 Diabetes Obesity
Interventions
BEHAVIORAL
No Results Yet
NCT05906238 | RECRUITING | NA
210 Participants

Interventions to Remedy the Negative Effects of Obesity Stigma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-10-10
Completion: 2027-04-30
Conditions
Obesity Stigma, Weight
Interventions
BEHAVIORAL
No Results Yet
NCT05865028 | SUSPENDED | PHASE2
32 Participants

A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-05-24
Completion: 2027-05-24
Conditions
Oropharyngeal Dysplasia Oral Cavity Dysplasia Oral Carcinoma in Situ
Interventions
DRUG
No Results Yet
NCT05863195 | RECRUITING | PHASE3
408 Participants

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-10-19
Completion: 2029-06-30
Conditions
Metastatic Colorectal Carcinoma Metastatic Malignant Neoplasm in the Liver Stage IV Colorectal Cancer AJCC v8 Unresectable Colorectal Carcinoma
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT05858008 | RECRUITING | NA
15 Participants

Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-04-01
Completion: 2026-06-30
Conditions
Mild Cognitive Impairment
Interventions
BEHAVIORAL
No Results Yet
NCT05829889 | RECRUITING | NA
960 Participants

Fractional Flow Reserve Versus Angiography for Treatment-Decision and Evaluation of Significant Left MAIN Coronary Artery Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-04-25
Completion: 2027-06-30
Conditions
Coronary Artery Disease Left Main Coronary Artery Disease
Interventions
PROCEDURE
No Results Yet
NCT05820386 | RECRUITING | NA
118 Participants

Skin-to-skin Contact During the Transfer From the Delivery Room to the Neonatal Intensive Care Unit: Impact on Very Preterm Infants and Their Parents

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-05-03
Completion: 2027-07-31
Conditions
Skin to Skin Premature Newborns
Interventions
PROCEDURE
No Results Yet
NCT05816850 | RECRUITING
654 Participants

Multilayer Biological Characterization of Advanced Follicular Lymphoma: a Translational Study From FIL_FOLL12 Trial

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2023-09-19
Completion: 2026-12-01
Conditions
Follicular Lymphoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05799339 | COMPLETED
144 Participants

Optimizing CAB-LA as PrEP for Women Who Inject Drugs

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2022-01-13
Completion: 2025-07-31
Conditions
HIV Infections Opioid Use Trauma, Psychological
No Results Yet
NCT05776082 | RECRUITING
5000 Participants

Association of Gestational Cardiovascular Health With Pregnancy Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2023-03-01
Completion: 2026-12-31
Conditions
Pregnant Women
Interventions
OTHER
No Results Yet
NCT05770596 | COMPLETED | NA
204 Participants

Vitamin C on Acute and Chronic Post Mastectomy Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-04-01
Completion: 2024-12-03
Conditions
Vitamin C Post-mastectomy Pain Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT05760534 | COMPLETED | PHASE4
110 Participants

Ideal Dosage for Sedation of Obese Patients Undergoing Knee or Hip Arthroplasty Under Spinal Anesthesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-03-06
Completion: 2025-11-25
Conditions
Arthritis Knee Arthritis Hip
Interventions
DRUG
No Results Yet
NCT05744427 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
725 Participants

Safety and Tolerability of JSKN003 in Chinese Subjects With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-03-15
Completion: 2025-12-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT05736562 | ACTIVE_NOT_RECRUITING | NA
70 Participants

Use of Ritual Epost Postnatal Multivitamins During the Postpartum Period

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-10-15
Completion: 2025-09-30
Conditions
Lactation Disorder - Postpartum Condition or Complication Nutrition, Healthy
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT05727176 | RECRUITING | PHASE2
120 Participants

Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-07-05
Completion: 2026-12-31
Conditions
Advanced Cholangiocarcinoma FGFR2 Fusions Gene Rearrangement
Interventions
DRUG
No Results Yet
NCT05721755 | RECRUITING | PHASE3
290 Participants

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-06-08
Completion: 2029-03-31
Conditions
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Metastatic Head and Neck Squamous Cell Carcinoma Metastatic Hypopharyngeal Squamous Cell Carcinoma Metastatic Laryngeal Squamous Cell Carcinoma Metastatic Oral Cavity Squamous Cell Carcinoma Metastatic Oropharyngeal Squamous Cell Carcinoma Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 Stage IV Hypopharyngeal Carcinoma AJCC v8 Stage IV Laryngeal Cancer AJCC v8 Stage IV Lip and Oral Cavity Cancer AJCC v8 Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
DRUG PROCEDURE BIOLOGICAL OTHER RADIATION
No Results Yet
NCT05710328 | RECRUITING | PHASE2
235 Participants

Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-05-10
Completion: 2027-05-31
Conditions
Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 HER2-Positive Breast Carcinoma Invasive Breast Carcinoma
Interventions
DRUG PROCEDURE OTHER
No Results Yet
NCT05704049 | ACTIVE_NOT_RECRUITING | PHASE2
118 Participants

A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-04-05
Completion: 2025-12-22
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05703672 | RECRUITING | PHASE3
500 Participants

Switching to E-cigarettes in Smokers Not Interested in Quitting

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2023-07-17
Completion: 2026-12-07
Conditions
Smoking Reduction
Interventions
DRUG OTHER
No Results Yet
NCT05702931 | RECRUITING | PHASE4
104 Participants

Semaglutide Treatment for Hyperglycaemia After Renal Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-09-19
Completion: 2027-12-31
Conditions
Hyperglycemia Renal Transplant Complication Primary Non-Function Diabetes
Interventions
DRUG
No Results Yet
NCT05657652 | RECRUITING | NA
36 Participants

CAV Regimen for R/R Ph- B-ALL

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2022-10-01
Completion: 2026-10-31
Conditions
Acute Lymphoblastic Leukemia
Interventions
DRUG
No Results Yet
NCT05657639 | RECRUITING | PHASE2
68 Participants

CAV Regimen for R/R AML

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2022-10-01
Completion: 2026-10-01
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
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