Clinical Trials
Showing trials with last updates posted in 2025.
25
Participants
Hepatic Lipid Metabolism-Alcohol Use Disorder
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2027-11-30
Conditions
Alcohol Use Disorder
Interventions
DIAGNOSTIC_TEST
No Results Yet
150
Participants
RESCUE: Discontinuation of GLP-1
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-17
Completion:
2026-06-30
Conditions
Obesity
Interventions
DEVICE
BEHAVIORAL
No Results Yet
110
Participants
Time Restricted Eating for WeIght LoSs MainTenance-2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-10-01
Completion:
2028-01-01
Conditions
Weight Loss Maintenance
Weight Gain
Weight Loss
Interventions
BEHAVIORAL
No Results Yet
108
Participants
An Open-Label Extension Study of Batoclimab in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-08-28
Completion:
2028-11-30
Conditions
Chronic Inflammatory Demyelinating Polyneuropathy
Interventions
DRUG
No Results Yet
197
Participants
Evaluating the Efficacy of a Ladies Gaelic Football-Specific Injury Prevention Programme
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-23
Completion:
2025-10-03
Conditions
Injury
Physical Performances
Interventions
BEHAVIORAL
No Results Yet
182
Participants
A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-10-08
Completion:
2027-03-08
Conditions
Arthritis, Rheumatoid
Interventions
DRUG
No Results Yet
920
Participants
A Study of LY4064809 With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-22
Completion:
2029-05-31
Conditions
Breast Neoplasms
Neoplasm Metastasis
Interventions
DRUG
No Results Yet
90
Participants
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2029-04-11
Conditions
Alzheimer s Disease
Mild Cognitive Impairment
Healthy
Interventions
DRUG
No Results Yet
274
Participants
Neurological Complications and ICU Workload After Emergency Repair of Acute Type A Aortic Dissection
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-01-01
Completion:
2025-04-30
Conditions
Aortic Dissection
Stroke
Paraplegia
AKI - Acute Kidney Injury
Coma
Delirium
No Results Yet
250
Participants
Observational, Bi-directional (Prospective and Retrospective) Study for Patients With Newly Diagnosed Ovarian Cancer Stages IA to IVB, or Persistent or Recurrent Disease From January 2021; Irrespective of Histology
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-09-19
Completion:
2026-03-31
Conditions
Ovarian Cancer
No Results Yet
60
Participants
At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-03
Completion:
2026-08-31
Conditions
Rheumatoid Arthritis (RA)
Interventions
DEVICE
DRUG
No Results Yet
39
Participants
Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-03-26
Completion:
2029-05-31
Conditions
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Recurrent Head and Neck Squamous Cell Carcinoma
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Oral Cavity Squamous Cell Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Recurrent Paranasal Sinus Squamous Cell Carcinoma
Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Stage III Hypopharyngeal Carcinoma AJCC v8
Stage III Laryngeal Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage III Sinonasal Cancer AJCC v8
Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Stage IVA Hypopharyngeal Carcinoma AJCC v8
Stage IVA Laryngeal Cancer AJCC v8
Stage IVA Lip and Oral Cavity Cancer AJCC v8
Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVA Sinonasal Cancer AJCC v8
Stage IVB Hypopharyngeal Carcinoma AJCC v8
Stage IVB Laryngeal Cancer AJCC v8
Stage IVB Lip and Oral Cavity Cancer AJCC v8
Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVB Sinonasal Cancer AJCC v8
Unresectable Head and Neck Squamous Cell Carcinoma
Unresectable Hypopharyngeal Squamous Cell Carcinoma
Unresectable Laryngeal Squamous Cell Carcinoma
Unresectable Oral Cavity Squamous Cell Carcinoma
Unresectable Oropharyngeal Squamous Cell Carcinoma
Unresectable Paranasal Sinus Squamous Cell Carcinoma
Interventions
PROCEDURE
DRUG
RADIATION
No Results Yet
430
Participants
A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-10
Completion:
2030-09-30
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
32
Participants
Upper Limb Function in Paraplegic Individuals: Exploring Endurance, Performance, and Symptoms
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-01-15
Completion:
2025-10-08
Conditions
Paraplegia
Endurance
Symptoms
No Results Yet
132
Participants
Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-05-27
Completion:
2030-04-26
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Interventions
PROCEDURE
DRUG
No Results Yet
80
Participants
Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2029-09-30
Conditions
Respiratory Tract Infection
Smell Disorder
Influenza
Rhinosinusitis
COVID-19
Depression
Parosmia
Hyposomia
Normosomia
Anosmia
No Results Yet
86
Participants
Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461) in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-03-31
Completion:
2027-09-01
Conditions
Metastatic Colorectal Adenocarcinoma
Refractory Colorectal Adenocarcinoma
Stage III Colorectal Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8
Unresectable Colorectal Adenocarcinoma
Interventions
PROCEDURE
BIOLOGICAL
DRUG
No Results Yet
500
Participants
Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2026-01-31
Completion:
2027-12-31
Conditions
Bladder Cancer
Non-muscle Invasive Bladder Cancer
No Results Yet
42
Participants
Effects of Kinesio Taping on Gait Biomechanics in Patellar Tendinopathy Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-08-31
Completion:
2025-12-01
Conditions
Patellar Tendinopathy / Jumpers Knee
Kinesio Taping
Interventions
BEHAVIORAL
No Results Yet
6
Participants
DK222 Study at Hopkins
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-02-01
Completion:
2027-02-01
Conditions
Non-Small Cell Lung Cancer
Urothelial Cancer
Interventions
DRUG
No Results Yet
50
Participants
EDEN Intracardiac Electrogram Recording and Classifying System
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2026-11-01
Conditions
Ventricular Arrhythmia
Interventions
DEVICE
No Results Yet
75
Participants
Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2034-08-01
Conditions
Tics
Functional Tics
No Results Yet
400
Participants
Platelet Volunteers, Longitudinal and Multi-omic Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2041-09-15
Conditions
Thrombosis
No Results Yet
36
Participants
Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-03-09
Completion:
2027-03-09
Conditions
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Invasive Breast Carcinoma
Locally Advanced Breast Carcinoma
Metastatic Breast Carcinoma
Metastatic HER2-Low Breast Carcinoma
Metastatic HER2-Positive Breast Carcinoma
Metastatic Hormone Receptor-Positive Breast Carcinoma
Metastatic Malignant Solid Neoplasm
Metastatic Triple-Negative Breast Carcinoma
Unresectable Breast Carcinoma
Unresectable HER2-Low Breast Carcinoma
Unresectable HER2-Positive Breast Carcinoma
Unresectable Hormone Receptor-Positive Breast Carcinoma
Unresectable Malignant Solid Neoplasm
Unresectable Triple-Negative Breast Carcinoma
Interventions
PROCEDURE
DRUG
BIOLOGICAL
No Results Yet
30
Participants
Validity of Thermal Imaging in Injury Risk Assessment in Volleyball Players
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-10-21
Completion:
2026-01-21
Conditions
Athletes
Interventions
DIAGNOSTIC_TEST
No Results Yet
315
Participants
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-09-26
Completion:
2027-06-15
Conditions
Radiographic Axial Spondyloarthritis
Interventions
DRUG
No Results Yet
226
Participants
Exercise Adherence and Cognitive Decline: Phase 2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-05
Completion:
2028-08-31
Conditions
Cognitive Decline
Interventions
BEHAVIORAL
No Results Yet
10
Participants
Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-09-10
Completion:
2028-09-01
Conditions
Chronic Granulomatous Disease (CGD)
Interventions
DRUG
OTHER
No Results Yet
300
Participants
FAST for DM Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2030-11-03
Conditions
Dermatomyositis (DM)
Juvenile Dermatomyositis (JDM)
Interventions
DIETARY_SUPPLEMENT
OTHER
No Results Yet
80
Participants
Causal Mechanisms of Odor-Guided Behavior in Humans
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2035-07-14
Conditions
Normal Physiology
Interventions
DEVICE
No Results Yet
400
Participants
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2029-12-12
Conditions
Aging
No Results Yet
126
Participants
Phase 3, Open Label Extension Study of ACP-204 in Lewy Body Dementia Psychosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-31
Completion:
2029-02-28
Conditions
Lewy Body Dementia Psychosis
Interventions
DRUG
No Results Yet
25
Participants
Power Nap With TES-TI
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-19
Completion:
2027-04-30
Conditions
Non-restorative Sleep
Healthy Volunteer
Interventions
DEVICE
No Results Yet
24
Participants
Mavacamten Enables Exercise in Hypertrophic Obstructive Cardiomyopathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-01
Completion:
2026-10-31
Conditions
Cardiomyopathy, Hypertrophic
Interventions
OTHER
No Results Yet
4580
Participants
A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-10
Completion:
2027-10-18
Conditions
Human Immunodeficiency Virus (HIV)
HIV Pre-Exposure Prophylaxis
Interventions
DRUG
No Results Yet
50
Participants
Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-03-31
Completion:
2027-09-19
Conditions
Burkitt Lymphoma
Double-Expressor Lymphoma
High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements
Interventions
PROCEDURE
DRUG
No Results Yet
30
Participants
Using Smartwatches to Monitor Smoking in Real-life Situations
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2026-04-30
Conditions
Smoking
No Results Yet
175
Participants
A Synthetic Lethality-Focused Algorithm to Identify Therapeutic Options in Advanced Metastatic Breast Cancer (SYNTHESIS-Breast)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2027-08-04
Conditions
Breast Cancer
Breast Carcinoma
Cancer of the Breast
Malignant Neoplasm of Breast
Interventions
DEVICE
No Results Yet
336
Participants
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-05
Completion:
2030-12-31
Conditions
Locally Advanced Cervical Adenocarcinoma
Locally Advanced Cervical Adenosquamous Carcinoma
Locally Advanced Cervical Squamous Cell Carcinoma
Stage IIIA Cervical Cancer FIGO 2018
Stage IIIB Cervical Cancer FIGO 2018
Stage IIIC1 Cervical Cancer FIGO 2018
Stage IIIC2 Cervical Cancer FIGO 2018
Stage IVA Cervical Cancer FIGO 2018
Interventions
PROCEDURE
RADIATION
DRUG
BIOLOGICAL
No Results Yet
111
Participants
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-25
Completion:
2027-07-31
Conditions
Muscle Invasive Bladder Urothelial Carcinoma
Stage II Bladder Cancer AJCC v8
Stage IIIA Bladder Cancer AJCC v8
Interventions
PROCEDURE
BIOLOGICAL
RADIATION
OTHER
No Results Yet
Showing 40 trials per page