Clinical Trials
Showing trials with last updates posted in 2025.
6
Participants
DK222 Study at Hopkins
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-02-01
Completion:
2027-02-01
Conditions
Non-Small Cell Lung Cancer
Urothelial Cancer
Interventions
DRUG
No Results Yet
30
Participants
Validity of Thermal Imaging in Injury Risk Assessment in Volleyball Players
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-10-21
Completion:
2026-01-21
Conditions
Athletes
Interventions
DIAGNOSTIC_TEST
No Results Yet
315
Participants
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-09-26
Completion:
2027-06-15
Conditions
Radiographic Axial Spondyloarthritis
Interventions
DRUG
No Results Yet
226
Participants
Exercise Adherence and Cognitive Decline: Phase 2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-05
Completion:
2028-08-31
Conditions
Cognitive Decline
Interventions
BEHAVIORAL
No Results Yet
10
Participants
Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-09-10
Completion:
2028-09-01
Conditions
Chronic Granulomatous Disease (CGD)
Interventions
DRUG
OTHER
No Results Yet
126
Participants
Phase 3, Open Label Extension Study of ACP-204 in Lewy Body Dementia Psychosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-31
Completion:
2029-02-28
Conditions
Lewy Body Dementia Psychosis
Interventions
DRUG
No Results Yet
25
Participants
Power Nap With TES-TI
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-19
Completion:
2027-04-30
Conditions
Non-restorative Sleep
Healthy Volunteer
Interventions
DEVICE
No Results Yet
24
Participants
Mavacamten Enables Exercise in Hypertrophic Obstructive Cardiomyopathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-01
Completion:
2026-10-31
Conditions
Cardiomyopathy, Hypertrophic
Interventions
OTHER
No Results Yet
4580
Participants
A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-10
Completion:
2027-10-18
Conditions
Human Immunodeficiency Virus (HIV)
HIV Pre-Exposure Prophylaxis
Interventions
DRUG
No Results Yet
100
Participants
A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-07-10
Completion:
2027-01-18
Conditions
HIV Infections
Interventions
BIOLOGICAL
DRUG
No Results Yet
550
Participants
Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-09-02
Completion:
2027-06-30
Conditions
Hereditary Cancer Syndromes
Interventions
GENETIC
No Results Yet
400
Participants
Evaluating the Safety and Efficacy of TLD in Patients With COPD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-02-15
Completion:
2027-05-31
Conditions
COPD
Chronic Obstructive Pulmonary Disease
Interventions
DEVICE
DRUG
No Results Yet
100
Participants
Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-07-24
Completion:
2027-11-30
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
2500
Participants
Effects of the Clinical Application of Traditional, Complementary and Integrative Medicine (TCIM) Procedures During Inpatient Stays in Germany
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-07-01
Completion:
2026-12-31
Conditions
Chronic Disease
Interventions
OTHER
No Results Yet
231
Participants
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-27
Completion:
2027-12-31
Conditions
Generalized Myasthenia Gravis
Interventions
DRUG
No Results Yet
100
Participants
A Novel Strategy for Evaluating Gallbladder Contraction Function by Ultrasound
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-26
Completion:
2025-12-20
Conditions
Gallbladder; Functional Disturbance
Interventions
DIAGNOSTIC_TEST
No Results Yet
88
Participants
A First-in-Human Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Multiple Oral Doses of Debio 1453P in Healthy Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-18
Completion:
2026-04-30
Conditions
Healthy Participants
Interventions
DRUG
No Results Yet
162
Participants
IMVT-1402 in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-03-18
Completion:
2028-08-31
Conditions
Chronic Inflammatory Demyelinating Polyneuropathy
Interventions
DRUG
No Results Yet
0
Participants
Investigating the Cognitive and Brain Health Benefits of Lean Pork Consumption
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-08-31
Completion:
2026-12-31
Conditions
Dietary Intervention
Dietary Proteins
Dietary Assessment
Older Adults (65 Years and Older)
Cognitive Ability, General
Interventions
DIETARY_SUPPLEMENT
No Results Yet
180
Participants
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-08-06
Completion:
2028-02-29
Conditions
Lewy Body Dementia Psychosis
Interventions
DRUG
No Results Yet
140
Participants
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-08-07
Completion:
2029-11-30
Conditions
Colorectal Cancer
Interventions
DRUG
No Results Yet
71
Participants
Nutritional Supplement for Treating Chemotherapy Induced Neuropathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-11-01
Completion:
2025-01-31
Conditions
Cancer
Neuropathy
Chemotherapy Induced Pain Neuropathy
Chemotherapy-Induced Peripheral Neuropathy
Interventions
DIETARY_SUPPLEMENT
No Results Yet
165
Participants
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-07-25
Completion:
2027-12-31
Conditions
Pericarditis
Pericarditis Acute
Recurrent Pericarditis
Interventions
DRUG
No Results Yet
38
Participants
PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-20
Completion:
2032-06-30
Conditions
Refractory Neuroblastoma
Relapsed Neuroblastoma
High-Risk Neuroblastoma
Interventions
BIOLOGICAL
No Results Yet
694
Participants
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-08-03
Completion:
2031-12-31
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
720
Participants
Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-16
Completion:
2028-12-31
Conditions
Surgical Incision
Wound Dehiscence
Surgical Site Infection
Incisional Hernia
Quality of Life
Interventions
DEVICE
No Results Yet
620
Participants
Inhaled Sedation in Critically Ill Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-15
Completion:
2027-03-31
Conditions
Sedation
Airway Extubation
Interventions
DRUG
No Results Yet
1110
Participants
An Ambispective Registry Study Comparing Clinical Outcomes of Surgical Interventions for the Treatment of Nasal Airway Obstruction.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-03-14
Completion:
2025-07-21
Conditions
Nasal Airway Obstruction
No Results Yet
190
Participants
Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-03
Completion:
2030-12-31
Conditions
Glioblastoma
Brain Cancer
Glioblastoma Multiforme
Glioblastoma Multiforme of Brain
Glioblastoma Multiforme, Adult
MGMT-Unmethylated Glioblastoma
MGMT-Methylated Glioblastoma
Interventions
DRUG
RADIATION
No Results Yet
100
Participants
Exercise Training for the Improvement of Immune Activity and Treatment Outcomes During Immunotherapy for Non-small Cell Lung Cancer, BOOST Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-01-23
Completion:
2028-05-31
Conditions
Lung Non-Small Cell Carcinoma
Interventions
OTHER
PROCEDURE
No Results Yet
56
Participants
A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-02-19
Completion:
2027-04-30
Conditions
Subacute Cutaneous Lupus Erythematosus
Chronic Cutaneous Lupus Erythematosus
Interventions
DRUG
No Results Yet
120
Participants
Pilot-Study for the Comparison of Biomarkers Between Regular Cannabis Users and Non-Users
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-19
Completion:
2026-12-31
Conditions
Driving Under the Influence of Cannabis
Interventions
DRUG
No Results Yet
180
Participants
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-20
Completion:
2027-02-28
Conditions
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
134
Participants
A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-30
Completion:
2031-11-30
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
40
Participants
Effects of Functional Inspiratory Muscle Training in Patients With Chronic Non-Specific Low Back Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-04-30
Completion:
2025-09-17
Conditions
Low Back Pain
Interventions
OTHER
No Results Yet
56
Participants
A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-09-15
Completion:
2026-10-31
Conditions
Malaria,Falciparum
Interventions
BIOLOGICAL
No Results Yet
60
Participants
Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-01-14
Completion:
2028-08-31
Conditions
Prostate Cancer
Prostate Cancer (Adenocarcinoma)
Prostate Cancer Metastatic Disease
Prostate Cancer Recurrent
Prostate Carcinoma
Prostate Neoplasm
Prostate Adenocarcinoma
Prostate Cancer With Bone Metastasis
Vasomotor Disturbance
Vasomotor Symptoms
Vasomotor Symptoms (VMS)
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Vasomotor Symptoms; Hot Flashes
Androgen Deprivation Therapy
Androgen Ablative Therapy of Advanced Hormone-dependent Prostate Carcinoma
Androgen-deprivation Therapy
Hot Flashes
Hot Flushes
Hot Flushes and/or Sweats
Interventions
DRUG
No Results Yet
147
Participants
Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-09
Completion:
2026-11-16
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
130
Participants
A Study to Assess Adverse Events and Change in Disease Activity of Oral ABBV-453 Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-07-23
Completion:
2030-12-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
75
Participants
A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-01
Completion:
2027-05-31
Conditions
Solid Tumor
Advanced Solid Tumor
Metastatic Solid Tumor
Immune Sensitive Tumor
Interventions
BIOLOGICAL
No Results Yet
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