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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07052266 | RECRUITING | NA
550 Participants

Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-09-02
Completion: 2027-06-30
Conditions
Hereditary Cancer Syndromes
Interventions
GENETIC
No Results Yet
NCT07051707 | NOT_YET_RECRUITING | PHASE3
400 Participants

Evaluating the Safety and Efficacy of TLD in Patients With COPD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-02-15
Completion: 2027-05-31
Conditions
COPD Chronic Obstructive Pulmonary Disease
Interventions
DEVICE DRUG
No Results Yet
NCT07040475 | RECRUITING
2500 Participants

Effects of the Clinical Application of Traditional, Complementary and Integrative Medicine (TCIM) Procedures During Inpatient Stays in Germany

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-07-01
Completion: 2026-12-31
Conditions
Chronic Disease
Interventions
OTHER
No Results Yet
NCT07039916 | RECRUITING | PHASE3
231 Participants

Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-27
Completion: 2027-12-31
Conditions
Generalized Myasthenia Gravis
Interventions
DRUG
No Results Yet
NCT07039864 | COMPLETED | NA
100 Participants

A Novel Strategy for Evaluating Gallbladder Contraction Function by Ultrasound

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-26
Completion: 2025-12-20
Conditions
Gallbladder; Functional Disturbance
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07035769 | RECRUITING | PHASE1
88 Participants

A First-in-Human Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Multiple Oral Doses of Debio 1453P in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-18
Completion: 2026-04-30
Conditions
Healthy Participants
Interventions
DRUG
No Results Yet
NCT07032662 | RECRUITING | PHASE2
162 Participants

IMVT-1402 in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-18
Completion: 2028-08-31
Conditions
Chronic Inflammatory Demyelinating Polyneuropathy
Interventions
DRUG
No Results Yet
NCT07031076 | WITHDRAWN | NA
0 Participants

Investigating the Cognitive and Brain Health Benefits of Lean Pork Consumption

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-31
Completion: 2026-12-31
Conditions
Dietary Intervention Dietary Proteins Dietary Assessment Older Adults (65 Years and Older) Cognitive Ability, General
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT07029581 | RECRUITING | PHASE2
180 Participants

Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-06
Completion: 2028-02-29
Conditions
Lewy Body Dementia Psychosis
Interventions
DRUG
No Results Yet
NCT07022938 | COMPLETED | PHASE4
71 Participants

Nutritional Supplement for Treating Chemotherapy Induced Neuropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-11-01
Completion: 2025-01-31
Conditions
Cancer Neuropathy Chemotherapy Induced Pain Neuropathy Chemotherapy-Induced Peripheral Neuropathy
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT07010159 | RECRUITING | PHASE2/PHASE3
165 Participants

Phase 2/3 Study of KPL-387 in Recurrent Pericarditis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-07-25
Completion: 2027-12-31
Conditions
Pericarditis Pericarditis Acute Recurrent Pericarditis
Interventions
DRUG
No Results Yet
NCT07007117 | RECRUITING | PHASE1
38 Participants

PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-20
Completion: 2032-06-30
Conditions
Refractory Neuroblastoma Relapsed Neuroblastoma High-Risk Neuroblastoma
Interventions
BIOLOGICAL
No Results Yet
NCT07005102 | RECRUITING | PHASE2/PHASE3
694 Participants

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-03
Completion: 2031-12-31
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT07003906 | RECRUITING | NA
720 Participants

Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-16
Completion: 2028-12-31
Conditions
Surgical Incision Wound Dehiscence Surgical Site Infection Incisional Hernia Quality of Life
Interventions
DEVICE
No Results Yet
NCT07000526 | RECRUITING | PHASE4
620 Participants

Inhaled Sedation in Critically Ill Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-15
Completion: 2027-03-31
Conditions
Sedation Airway Extubation
Interventions
DRUG
No Results Yet
NCT06992037 | COMPLETED
1110 Participants

An Ambispective Registry Study Comparing Clinical Outcomes of Surgical Interventions for the Treatment of Nasal Airway Obstruction.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-14
Completion: 2025-07-21
Conditions
Nasal Airway Obstruction
No Results Yet
NCT06991101 | RECRUITING | PHASE2
190 Participants

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-03
Completion: 2030-12-31
Conditions
Glioblastoma Brain Cancer Glioblastoma Multiforme Glioblastoma Multiforme of Brain Glioblastoma Multiforme, Adult MGMT-Unmethylated Glioblastoma MGMT-Methylated Glioblastoma
Interventions
DRUG RADIATION
No Results Yet
NCT06983899 | RECRUITING | NA
100 Participants

Exercise Training for the Improvement of Immune Activity and Treatment Outcomes During Immunotherapy for Non-small Cell Lung Cancer, BOOST Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-23
Completion: 2028-05-31
Conditions
Lung Non-Small Cell Carcinoma
Interventions
OTHER PROCEDURE
No Results Yet
NCT06980805 | RECRUITING | PHASE2
56 Participants

A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-19
Completion: 2027-04-30
Conditions
Subacute Cutaneous Lupus Erythematosus Chronic Cutaneous Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT06975020 | RECRUITING | NA
120 Participants

Pilot-Study for the Comparison of Biomarkers Between Regular Cannabis Users and Non-Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-19
Completion: 2026-12-31
Conditions
Driving Under the Influence of Cannabis
Interventions
DRUG
No Results Yet
NCT06969430 | RECRUITING | PHASE1/PHASE2
134 Participants

A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-30
Completion: 2031-11-30
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT06958744 | COMPLETED | NA
40 Participants

Effects of Functional Inspiratory Muscle Training in Patients With Chronic Non-Specific Low Back Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-30
Completion: 2025-09-17
Conditions
Low Back Pain
Interventions
OTHER
No Results Yet
NCT06958198 | RECRUITING | PHASE1
56 Participants

A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-09-15
Completion: 2026-10-31
Conditions
Malaria,Falciparum
Interventions
BIOLOGICAL
No Results Yet
NCT06957691 | RECRUITING | PHASE2
60 Participants

Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-14
Completion: 2028-08-31
Conditions
Prostate Cancer Prostate Cancer (Adenocarcinoma) Prostate Cancer Metastatic Disease Prostate Cancer Recurrent Prostate Carcinoma Prostate Neoplasm Prostate Adenocarcinoma Prostate Cancer With Bone Metastasis Vasomotor Disturbance Vasomotor Symptoms Vasomotor Symptoms (VMS) Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men Vasomotor Symptoms; Hot Flashes Androgen Deprivation Therapy Androgen Ablative Therapy of Advanced Hormone-dependent Prostate Carcinoma Androgen-deprivation Therapy Hot Flashes Hot Flushes Hot Flushes and/or Sweats
Interventions
DRUG
No Results Yet
NCT06956235 | ACTIVE_NOT_RECRUITING | PHASE2
147 Participants

Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-09
Completion: 2026-11-16
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT06952010 | RECRUITING | PHASE1
75 Participants

A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-01
Completion: 2027-05-31
Conditions
Solid Tumor Advanced Solid Tumor Metastatic Solid Tumor Immune Sensitive Tumor
Interventions
BIOLOGICAL
No Results Yet
NCT06950294 | NOT_YET_RECRUITING | EARLY_PHASE1
34 Participants

iNO300 Therapy in Critically Ill Patients With Pneumonia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-31
Completion: 2026-12-31
Conditions
Critical Illness Pneumonia
Interventions
DRUG OTHER
No Results Yet
NCT06949475 | COMPLETED
60 Participants

Dual Task and Upper Extremity Performance in Children With Myelomeningocele

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-26
Completion: 2025-12-01
Conditions
Meningomyelocele
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06949410 | RECRUITING | PHASE1
36 Participants

HER2 Vaccine for Locally Advanced Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-03-31
Completion: 2029-12-31
Conditions
Breast Cancer HER2-positive Breast Cancer
Interventions
DRUG
No Results Yet
NCT06946524 | COMPLETED | PHASE1
59 Participants

A Study to Assess the Bioavailability of Risankizumab Following Subcutaneous Administration With Prefilled Pen Relative to a Prefilled Syringe in Healthy Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-08
Completion: 2025-11-25
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06942442 | RECRUITING | PHASE2
47 Participants

A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-22
Completion: 2030-10-01
Conditions
HLA-A*0201 Positive Cells Present Clear Cell Sarcoma (CCS)
Interventions
DRUG
No Results Yet
NCT06942195 | RECRUITING | NA
8 Participants

Effects of Calcium on Gut Functions and Blood Glucose in Humans With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-22
Completion: 2026-03-28
Conditions
T2DM
Interventions
OTHER
No Results Yet
NCT06935357 | RECRUITING | PHASE3
454 Participants

A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-08
Completion: 2027-05-31
Conditions
Immunoglobulin A Nephropathy (IgAN)
Interventions
DRUG
No Results Yet
NCT06934889 | RECRUITING | PHASE1
60 Participants

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-07
Completion: 2028-04-30
Conditions
Glioblastoma Gliosarcoma
Interventions
DRUG RADIATION
No Results Yet
NCT06934382 | RECRUITING | PHASE1
33 Participants

Anti-CD7 CAR-T Cells in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia or Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-29
Completion: 2029-05-30
Conditions
T-Cell Acute Lymphoblastic Leukemia/Lymphoma
Interventions
BIOLOGICAL
No Results Yet
NCT06933043 | COMPLETED | PHASE1
24 Participants

A Study on the Safety, Tolerability, Bioavailability and Mechanism of Action of Intravenous NAV-240 in Adults.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-20
Completion: 2025-11-20
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06932666 | RECRUITING | NA
60 Participants

Why Calories Are Not the Same - a Gut Explanation?

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-15
Completion: 2026-12-31
Conditions
Diet, Healthy Breath Analysis
Interventions
OTHER
No Results Yet
NCT06930625 | RECRUITING | PHASE3
119 Participants

A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-11-26
Completion: 2028-06-30
Conditions
Acromegaly
Interventions
DRUG
No Results Yet
NCT06924970 | RECRUITING | PHASE2
56 Participants

A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-01
Completion: 2026-05-31
Conditions
Sickle Cell Disease
Interventions
DRUG
No Results Yet
NCT06903104 | COMPLETED | NA
20 Participants

Acceptability and Feasibility of a Stress Prevention Program Based on Meditation and Acceptance and Commitment Therapy for Staff at a Cancer Center

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-13
Completion: 2025-04-30
Conditions
Employees at a Hospital
Interventions
OTHER DIAGNOSTIC_TEST
No Results Yet
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