Clinical Trials

Showing trials with last updates posted in 2025.

NCT06865482 | RECRUITING
65 Participants

Clinical Course Of Disease In Participants With FA-CM

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-09-30
Completion: 2027-09-30
Conditions
Friedreich Ataxia Cardiomyopathy
No Results Yet
NCT06863142 | RECRUITING | PHASE1
45 Participants

Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-28
Completion: 2026-07-31
Conditions
Influenza Prevention Seasonal Influenza
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06861452 | RECRUITING | PHASE1/PHASE2
9 Participants

Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-25
Completion: 2026-07-29
Conditions
Locally Advanced Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06860607 | RECRUITING | PHASE1
44 Participants

Environment and Alcohol: A Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2027-03-01
Conditions
Alcohol Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06860594 | RECRUITING | PHASE1
30 Participants

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-07-30
Completion: 2027-06-30
Conditions
Astrocytoma, IDH-Mutant, Grade 2 Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-Mutant Recurrent Adult Diffuse Midline Glioma, H3 K27-Mutant Recurrent Astrocytoma, IDH-Mutant Recurrent Astrocytoma, IDH-Mutant, Grade 3 Recurrent Astrocytoma, IDH-Mutant, Grade 4 Recurrent Glioblastoma, IDH-Wildtype
Interventions
PROCEDURE RADIATION DRUG
No Results Yet
NCT06859788 | RECRUITING | PHASE3
200 Participants

SPI-1005 for the Treatment of Meniere's Disease (Open Label)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-29
Completion: 2026-12-31
Conditions
Meniere's Disease Ménière's Disease
Interventions
DRUG
No Results Yet
NCT06859099 | ENROLLING_BY_INVITATION | PHASE3
300 Participants

Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-01
Completion: 2029-10-03
Conditions
Polyneuropathy, Inflammatory Demyelinating, Chronic
Interventions
DRUG
No Results Yet
NCT06856226 | RECRUITING
88 Participants

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2027-12-01
Conditions
Leukemia Lymphoma Hematologic Malignancy
Interventions
OTHER
No Results Yet
NCT06853665 | NOT_YET_RECRUITING | PHASE4
196 Participants

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-10
Completion: 2030-01-10
Conditions
Attention Deficit Hyperactivity Disorder (ADHD) Autism Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT06846320 | RECRUITING | PHASE2
315 Participants

Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-29
Completion: 2026-11-30
Conditions
Generalized Anxiety Disorder (GAD)
Interventions
DRUG
No Results Yet
NCT06838871 | COMPLETED | NA
20 Participants

Effects of Inspiratory Muscle Training and Abdominal Drawing-In Maneuver on Balance, Gait and Pulmonary Function in Stroke Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-24
Completion: 2025-04-25
Conditions
Subacute Stroke Balance Deficits
Interventions
BEHAVIORAL
No Results Yet
NCT06835296 | COMPLETED | PHASE1
47 Participants

A Study of Oral YUQ-A1007 in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-20
Completion: 2025-09-30
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT06828380 | RECRUITING | PHASE2
128 Participants

A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-15
Completion: 2028-08-06
Conditions
Advanced Hepatocellular Carcinoma (HCC)
Interventions
RADIATION
No Results Yet
NCT06828263 | RECRUITING
130 Participants

Prospective Evaluation of Imaging Response Biomarkers During [177Lu]Lu-PSMA in Metastatic Castration-resistant Prostate Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-08-01
Completion: 2043-06-30
Conditions
Prostate Cancer Metastatic Disease
No Results Yet
NCT06823271 | RECRUITING | NA
20 Participants

Haemodynamics and Ventricular Arrhythmias During Exercise in Patients With Arrhythmogenic Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-01
Completion: 2026-06-30
Conditions
Arrhythmias, Cardiac
Interventions
OTHER
No Results Yet
NCT06819176 | RECRUITING | PHASE1
50 Participants

Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2028-09-01
Conditions
Human Immunodeficiency Virus
Interventions
DRUG
No Results Yet
NCT06817889 | RECRUITING | PHASE2
60 Participants

Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-23
Completion: 2027-11-30
Conditions
Hematopoietic and Lymphatic System Neoplasm Autoimmune Disease Respiratory Syncytial Virus Infection
Interventions
DRUG OTHER PROCEDURE
No Results Yet
NCT06816524 | NOT_YET_RECRUITING | NA
324 Participants

The Effects of Iron Treatment on Malaria and Measles Vaccine Response in Kenyan Infants With Iron Deficiency

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-05
Completion: 2027-12-31
Conditions
Iron Deficiencies
Interventions
DIETARY_SUPPLEMENT BIOLOGICAL
No Results Yet
NCT06811129 | RECRUITING
410 Participants

Long-Term Neurologic and Neurocognitive Sequelae Following Pediatric Ebola Virus in Liberia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2026-11-01
Conditions
Ebola Post-Acute Ebola Syndrome
No Results Yet
NCT06803875 | RECRUITING | PHASE1/PHASE2
42 Participants

Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-01-31
Completion: 2027-12-31
Conditions
Relapsed Neuroblastoma Refractory Neuroblastoma High-risk Neuroblastoma
Interventions
BIOLOGICAL
No Results Yet
NCT06802523 | SUSPENDED | PHASE1
53 Participants

Testing the Combination of Targeted Radiotherapy With Anti-Cancer Drugs, Venetoclax and ASTX-727, to Improve Outcomes for Adults With Newly Diagnosed Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-04-21
Completion: 2028-12-31
Conditions
Acute Myeloid Leukemia
Interventions
RADIATION PROCEDURE DRUG
No Results Yet
NCT06801015 | ACTIVE_NOT_RECRUITING | PHASE4
30 Participants

Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor Functions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-01
Completion: 2028-01-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06789445 | RECRUITING | PHASE1/PHASE2
54 Participants

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-10
Completion: 2029-10-31
Conditions
Primary Photoreceptor Disease Retinitis Pigmentosa (RP) Usher Syndrome Cone-Rod Dystrophy Inherited Retinal Disease (IRD) Rod-Cone Dystrophy Rod-Cone Disease Cone-Rod Disease Retinal Degeneration
Interventions
BIOLOGICAL
No Results Yet
NCT06774924 | RECRUITING | NA
100 Participants

"Clinical Ultrasound, a New Link Between Town and Hospital in Seine-Saint-Denis". (ECHO93)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-12
Completion: 2026-09-30
Conditions
Diagnosis Clinical Ultrasound
Interventions
DEVICE
No Results Yet
NCT06773104 | COMPLETED | NA
24 Participants

Autogenous Tooth Bone Graft Versus Allogeneic Bone Graft Around Dental Implant in Aesthetic Zone

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-03-25
Completion: 2025-01-16
Conditions
Immediate Dental Implants Thin Labial Plate of Bone Pre-extraction Hopeless Tooth in Esthetic Zone
Interventions
PROCEDURE
No Results Yet
NCT06770582 | RECRUITING | PHASE2
160 Participants

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-03
Completion: 2032-02-01
Conditions
Non-Muscle Invasive Bladder Urothelial Carcinoma Recurrent Non-Muscle Invasive Bladder Urothelial Carcinoma Stage I Bladder Cancer AJCC v8
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER RADIATION
No Results Yet
NCT06764706 | RECRUITING
200 Participants

Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe Ulcerative Colitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-27
Completion: 2028-07-31
Conditions
Ulcerative Colitis
No Results Yet
NCT06752941 | RECRUITING
36 Participants

LOW-PV Continuation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-30
Completion: 2026-03-30
Conditions
Polycythemia Vera
No Results Yet
NCT06748092 | RECRUITING | NA
250 Participants

Clinical Validation of iCare IC1000 Tonometer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-21
Completion: 2026-02-28
Conditions
Intraocular Pressure
Interventions
DEVICE
No Results Yet
NCT06745076 | RECRUITING | PHASE2
125 Participants

Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-06
Completion: 2032-01-03
Conditions
Advanced Hodgkin Lymphoma Classic Hodgkin Lymphoma Lugano Classification Stage III Hodgkin Lymphoma AJCC v8 Lugano Classification Stage IV Hodgkin Lymphoma AJCC v8
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER
No Results Yet
NCT06744283 | RECRUITING
20 Participants

Experience and Management of Cancer Screening-Related Anxiety in Fanconi Anemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2026-01-30
Conditions
Fanconi Anemia
No Results Yet
NCT06744218 | RECRUITING | NA
46 Participants

Effectiveness of Telerehabilitation as an Alternative to Outpatient Physiotherapy in the 1 Month After Arthroscopic Rotator Cuff Repair Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-22
Completion: 2026-10-31
Conditions
Rotator Cuff Injuries
Interventions
PROCEDURE
No Results Yet
NCT06736106 | RECRUITING | NA
200 Participants

Which Markers of Musculoskeletal Health Can Explain Complications in Spinal Surgery?

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-09-01
Completion: 2026-08-31
Conditions
Spine Injuries and Disorders
Interventions
OTHER
No Results Yet
NCT06732401 | RECRUITING | PHASE3
630 Participants

Testing the Addition of AZD6738 (Ceralasertib) to Immunotherapy to Increase Time Without Cancer for Patients With Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-07
Completion: 2028-06-30
Conditions
Lung Non-Small Cell Carcinoma Stage II Lung Cancer AJCC v8 Stage IIIA Lung Cancer AJCC v8 Stage IIIB Lung Cancer AJCC v8
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06727604 | RECRUITING | PHASE2
240 Participants

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-12-17
Completion: 2028-06-30
Conditions
Graves' Disease
Interventions
DRUG
No Results Yet
NCT06726629 | RECRUITING
200 Participants

Crosscultural Adaptation And Validation Of The Italian Version Of The New Knee Society Knee Scoring System

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-01
Completion: 2026-11-30
Conditions
Knee Osteoarthritis
Interventions
OTHER
No Results Yet
NCT06717477 | ENROLLING_BY_INVITATION
200 Participants

Streamlining Care for Patients With Compression Neuropathies: The Carpal Tunnel Plus Pathway

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-18
Completion: 2026-03-31
Conditions
Carpal Tunnel Syndrome (CTS)
Interventions
PROCEDURE
No Results Yet
NCT06714253 | RECRUITING | PHASE1/PHASE2
42 Participants

Study of Circular RNA Treatment in Patients With Radiation Induced Xerostomia-1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-05
Completion: 2027-08-31
Conditions
Radiation-Induced Xerostomia and Hyposalivation
Interventions
BIOLOGICAL
No Results Yet
NCT06707207 | RECRUITING
40 Participants

Predicting Future Errors During Skill Performance

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2029-04-01
Conditions
Healthy
No Results Yet
NCT06695325 | RECRUITING
300 Participants

Convenient Home Access for Routine Monitoring in Diabetes (Charm-D Study)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-11-04
Completion: 2026-07-01
Conditions
Diabetes Mellitus
Interventions
DIAGNOSTIC_TEST
No Results Yet
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