Clinical Trials
Showing trials with last updates posted in 2025.
40
Participants
Pharmacokinetics, Safety, and Tolerability Study of GOPRELTO® Nasal Solution and NUMBRINO™ Nasal Solution
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-06
Completion:
2027-12-31
Conditions
ENT Disorder
Nasal Procedures
Nasal Anesthesia
Nasal Mucosa Surgery
Interventions
DRUG
No Results Yet
50
Participants
Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-07-20
Completion:
2027-12-31
Conditions
Lung Carcinoma
Stage I Lung Cancer AJCC v8
Stage IA1 Lung Cancer AJCC v8
Stage IA2 Lung Cancer AJCC v8
Stage IA3 Lung Cancer AJCC v8
Stage IB Lung Cancer AJCC v8
Stage II Lung Cancer AJCC v8
Stage IIA Lung Cancer AJCC v8
Stage IIB Lung Cancer AJCC v8
Stage III Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Interventions
DRUG
OTHER
No Results Yet
586
Participants
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-05-05
Completion:
2024-09-11
Conditions
Parkinsons Disease
Interventions
DRUG
230
Participants
Trial to Assess the Safety and Efficacy of Sirolimus-Coated Balloon vs. Uncoated Standard Angioplasty for the Treatment of Below-the-knee Peripheral Arterial Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2022-02-10
Completion:
2026-04-17
Conditions
Peripheral Artery Disease
Interventions
COMBINATION_PRODUCT
DEVICE
No Results Yet
264
Participants
Covid-19 Vaccine Response in Elderly Subjects
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-02-18
Completion:
2023-03-28
Conditions
Covid19 Vaccine
Interventions
BIOLOGICAL
No Results Yet
443
Participants
Effect of Increased Oxytocin Doses on the Mode of Delivery in Obese Primiparous Women With Spontaneous or Induced Labour
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-10-02
Completion:
2024-12-30
Conditions
Obese
Primiparous Women
Oxytocin
Interventions
DRUG
No Results Yet
31
Participants
QUANTRA® References Range Protocol in Pregnancy and Postpartum
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-05-05
Completion:
2022-11-07
Conditions
Pregnancy Postpartum
No Results Yet
12166
Participants
Prevent and Control COVID-19 Infection in Nursing Homes on the Risk of Death of Residents
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-07-08
Completion:
2022-03-31
Conditions
Covid19
Interventions
OTHER
No Results Yet
1
Participants
Intravenous ACP-501 for Familial LCAT Deficiency (rhLCAT)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2013-01-24
Completion:
2013-12-12
Conditions
Familial LCAT Deficiency
Interventions
DRUG
No Results Yet
55
Participants
A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-10-05
Completion:
2026-11-30
Conditions
Oropharyngeal Cancer
Neck Cancer
Human Papillomavirus
HPV
Anal Cancer
Cervical Cancer
Penile Cancer
Vulvar Cancer
Vaginal Cancer
Colon Cancer
Interventions
DRUG
No Results Yet
650
Participants
Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-04-29
Completion:
2040-02-01
Conditions
Androgen Insensitivity Syndrome
Metabolic Parameters in AIS, CAIS, PAIS and MAIS
Tumor Formation in AIS, CAIS, PAIS and MAIS
Sexual Function AIS, CAIS, PAIS and MAIS
No Results Yet
143
Participants
Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2023-03-31
Completion:
2026-10-31
Conditions
Primary Sclerosing Cholangitis
No Results Yet
15
Participants
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-04-08
Completion:
2026-12-01
Conditions
High Grade Glioma
Diffuse Intrinsic Pontine Glioma
Interventions
DRUG
PROCEDURE
No Results Yet
16
Participants
A Powered Exoskeleton for Veterans With Knee OA
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-06-01
Completion:
2026-03-31
Conditions
Knee Osteoarthritis
Interventions
DEVICE
No Results Yet
244
Participants
Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-11-09
Completion:
2027-04-15
Conditions
Healthy Children
Children With Neurodevelopmental Disorders
Children With Neuropsychiatric Disorders
Children With Behavioral Syndromes
No Results Yet
39
Participants
The Life Paths That Lead Teenagers to Attempted Suicide:Trajectories of Proximal Adversity
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2019-11-01
Completion:
2022-12-31
Conditions
Suicide, Attempted
No Results Yet
5
Participants
Pharmacogenomic Modulators of Impaired Exercise Adaptation in Statin Users
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-06-03
Completion:
2023-07-30
Conditions
HMG-CoA Reductase Inhibitor Toxicity
Interventions
OTHER
No Results Yet
200000
Participants
Connect for Cancer Prevention Study (Connect)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-07-26
Completion:
2070-12-31
Conditions
Cancer
General Research Use
No Results Yet
231
Participants
Factors Influencing Fertility or Pregnancy Health
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-10-19
Completion:
2030-12-31
Conditions
Menstrual Cycles
Conception
Early Pregnancy Loss
Pregnancy Outcomes
No Results Yet
2500
Participants
The Best Care for Abdominal Emergencies Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-01-08
Completion:
2022-05-01
Conditions
Acute Abdomen
Bowel Obstruction
Bowel; Ischemic, Acute
Bowel Perforated
Peritonitis
Interventions
PROCEDURE
No Results Yet
22
Participants
Corticotrophin-releasing Hormone (CRH) Stimulation for 18F-FDG-PET Detection of Pituitary Adenoma in Cushing s Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2025-12-31
Conditions
Cushing's Disease
Pituitary Adenoma
Interventions
DRUG
No Results Yet
400
Participants
Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-12-18
Completion:
2040-12-30
Conditions
Gastric Cancer
Gastric Neoplasm
Gastrointestinal Stromal Sarcoma
Gastrointestinal Stromal Neoplasm
Gastrointestinal Stromal Tumor (GIST)
No Results Yet
50
Participants
Auricular VNS Following Subarachnoid Hemorrhage
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-01-05
Completion:
2026-06-30
Conditions
Subarachnoid Hemorrhage
Interventions
DEVICE
No Results Yet
225
Participants
A Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Forimtamig in Participants With Relapsed or Refractory Multiple Myeloma (r/r MM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-11-11
Completion:
2026-02-20
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
60
Participants
Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-08-25
Completion:
2027-06-30
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
DRUG
BIOLOGICAL
No Results Yet
200
Participants
Neuronal Mechanisms of Human Episodic Memory
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-08-12
Completion:
2026-07-31
Conditions
Epilepsy Intractable
Interventions
BEHAVIORAL
No Results Yet
30
Participants
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2018-09-01
Completion:
2026-01-31
Conditions
Atherosclerosis
Stress
Inflammation
Interventions
BEHAVIORAL
No Results Yet
150
Participants
Ankle Instability Using Foot Intensive Rehabilitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-10-28
Completion:
2026-12-01
Conditions
Ankle Injuries
Ankle Sprains
Interventions
BEHAVIORAL
No Results Yet
240
Participants
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-07-14
Completion:
2027-06-01
Conditions
Cancer
Interventions
DRUG
No Results Yet
478
Participants
Sirolimus- vs. Paclitaxel-Drug Coated Ballons in Patients With Peripheral Artery Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-04-13
Completion:
2023-12-31
Conditions
Peripheral Artery Disease
Interventions
COMBINATION_PRODUCT
No Results Yet
12
Participants
Study of Tumor Treating Fields With Hypofractionated Chemoradiotherapy in Newly Diagnosed Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-05-21
Completion:
2024-11-14
Conditions
Glioblastoma
Newly Diagnosed Glioblastoma
Interventions
DEVICE
DRUG
RADIATION
No Results Yet
407
Participants
A Communication Tool to Assist Older Adults Facing Dialysis Choices
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-11-02
Completion:
2025-11-10
Conditions
Palliative Care
Kidney Failure, Chronic
Decision Making
Decision Support Techniques
Renal Dialysis
Dialysis
Kidney Diseases
Nephrologists
Decision Aid
End of Life
End-Stage Renal Disease
Late-Stage Renal Disease
Communication
Life-Supporting Treatments
Interventions
OTHER
No Results Yet
152
Participants
Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-10-08
Completion:
2027-03-31
Conditions
Early Stage Breast Cancer
Interventions
OTHER
No Results Yet
10000
Participants
Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-06-16
Completion:
2040-12-31
Conditions
Wide Spectrum of Diseases
Hematologic Diseases
No Results Yet
83
Participants
Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer/Tumor Pain
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-10-27
Completion:
2024-03-27
Conditions
Cancer
Neoplasms
Solid Tumors
No Results Yet
583
Participants
A Longitudinal Study of COVID-19 Sequelae and Immunity
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-06-17
Completion:
2027-12-31
Conditions
COVID-19
No Results Yet
160
Participants
Reducing Stroke Risk in African-American Men
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-05-05
Completion:
2025-09-08
Conditions
Stroke
Transient Ischemic Attack
Interventions
BEHAVIORAL
No Results Yet
721
Participants
Genetics of COVID-19 Susceptibility and Manifestations
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-05-05
Completion:
2021-11-23
Conditions
COVID-19
Coronavirus 2019
No Results Yet
48995
Participants
Prevention of Colorectal Cancer Through Multiomics Blood Testing
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-05-20
Completion:
2024-02-29
Conditions
Colon Cancer
Rectal Cancer
Colon Neoplasm
Colon Diseases
Colon Lesion
Colon Polyp
Colorectal Cancer
Polyp
Adenoma
Rectal Diseases
Gastrointestinal Tract Cancers
Interventions
DIAGNOSTIC_TEST
500
Participants
The GErman Italian Spanish Takotsubo (GEIST) Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2015-04-30
Completion:
2035-12-31
Conditions
Takotsubo Syndrome
No Results Yet
Showing 40 trials per page