Clinical Trials

Showing trials with last updates posted in 2025.

NCT04577339 | COMPLETED
2500 Participants

The Best Care for Abdominal Emergencies Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-01-08
Completion: 2022-05-01
Conditions
Acute Abdomen Bowel Obstruction Bowel; Ischemic, Acute Bowel Perforated Peritonitis
Interventions
PROCEDURE
No Results Yet
NCT04557618 | RECRUITING | NA
50 Participants

Auricular VNS Following Subarachnoid Hemorrhage

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-01-05
Completion: 2026-06-30
Conditions
Subarachnoid Hemorrhage
Interventions
DEVICE
No Results Yet
NCT04557150 | ACTIVE_NOT_RECRUITING | PHASE1
225 Participants

A Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Forimtamig in Participants With Relapsed or Refractory Multiple Myeloma (r/r MM)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-11-11
Completion: 2026-02-20
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT04505254 | RECRUITING | PHASE2
60 Participants

Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-08-25
Completion: 2027-06-30
Conditions
Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT04500119 | ENROLLING_BY_INVITATION | NA
200 Participants

Neuronal Mechanisms of Human Episodic Memory

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-08-12
Completion: 2026-07-31
Conditions
Epilepsy Intractable
Interventions
BEHAVIORAL
No Results Yet
NCT04496947 | RECRUITING | NA
30 Participants

Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-09-01
Completion: 2026-01-31
Conditions
Atherosclerosis Stress Inflammation
Interventions
BEHAVIORAL
No Results Yet
NCT04493645 | ACTIVE_NOT_RECRUITING | NA
150 Participants

Ankle Instability Using Foot Intensive Rehabilitation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-10-28
Completion: 2026-12-01
Conditions
Ankle Injuries Ankle Sprains
Interventions
BEHAVIORAL
No Results Yet
NCT04485013 | RECRUITING | PHASE1
240 Participants

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-07-14
Completion: 2027-06-01
Conditions
Cancer
Interventions
DRUG
No Results Yet
NCT04475783 | ACTIVE_NOT_RECRUITING | NA
478 Participants

Sirolimus- vs. Paclitaxel-Drug Coated Ballons in Patients With Peripheral Artery Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-04-13
Completion: 2023-12-31
Conditions
Peripheral Artery Disease
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT04474353 | COMPLETED | PHASE1
12 Participants

Study of Tumor Treating Fields With Hypofractionated Chemoradiotherapy in Newly Diagnosed Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-05-21
Completion: 2024-11-14
Conditions
Glioblastoma Newly Diagnosed Glioblastoma
Interventions
DEVICE DRUG RADIATION
No Results Yet
NCT04466865 | COMPLETED | NA
407 Participants

A Communication Tool to Assist Older Adults Facing Dialysis Choices

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-11-02
Completion: 2025-11-10
Conditions
Palliative Care Kidney Failure, Chronic Decision Making Decision Support Techniques Renal Dialysis Dialysis Kidney Diseases Nephrologists Decision Aid End of Life End-Stage Renal Disease Late-Stage Renal Disease Communication Life-Supporting Treatments
Interventions
OTHER
No Results Yet
NCT04458532 | RECRUITING | NA
152 Participants

Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-10-08
Completion: 2027-03-31
Conditions
Early Stage Breast Cancer
Interventions
OTHER
No Results Yet
NCT04402125 | COMPLETED | NA
160 Participants

Reducing Stroke Risk in African-American Men

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-05-05
Completion: 2025-09-08
Conditions
Stroke Transient Ischemic Attack
Interventions
BEHAVIORAL
No Results Yet
NCT04371432 | COMPLETED
721 Participants

Genetics of COVID-19 Susceptibility and Manifestations

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2020-05-05
Completion: 2021-11-23
Conditions
COVID-19 Coronavirus 2019
No Results Yet
NCT04369053 | COMPLETED
48995 Participants

Prevention of Colorectal Cancer Through Multiomics Blood Testing

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2020-05-20
Completion: 2024-02-29
Conditions
Colon Cancer Rectal Cancer Colon Neoplasm Colon Diseases Colon Lesion Colon Polyp Colorectal Cancer Polyp Adenoma Rectal Diseases Gastrointestinal Tract Cancers
Interventions
DIAGNOSTIC_TEST
NCT04361994 | RECRUITING
500 Participants

The GErman Italian Spanish Takotsubo (GEIST) Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2015-04-30
Completion: 2035-12-31
Conditions
Takotsubo Syndrome
No Results Yet
NCT04324944 | COMPLETED | NA
39 Participants

Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-07-05
Completion: 2025-09-13
Conditions
Schizophrenia Schizoaffective Disorder Delusional Disorder Major Depressive Disorder With Psychotic Features
Interventions
BEHAVIORAL
No Results Yet
NCT04319939 | COMPLETED
66 Participants

Diaphragm Ultrasound Measurements With Variations in Modes of Ventilation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2020-02-05
Completion: 2022-04-11
Conditions
Mechanical Ventilation
Interventions
OTHER
No Results Yet
NCT04296305 | ACTIVE_NOT_RECRUITING | PHASE4
84 Participants

Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-09-10
Completion: 2027-12-31
Conditions
Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm
Interventions
DRUG OTHER
No Results Yet
NCT04278313 | RECRUITING | NA
90 Participants

Ovarian Function Following Intraovarian Injection of PRP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-02-24
Completion: 2026-07-31
Conditions
Diminished Ovarian Reserve Diminished Ovarian Reserve Due to Advanced Maternal Age
Interventions
PROCEDURE
No Results Yet
NCT04267848 | RECRUITING | PHASE3
1210 Participants

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-06-16
Completion: 2025-12-15
Conditions
Lung Non-Small Cell Carcinoma Lung Non-Small Cell Squamous Carcinoma Lung Non-Squamous Non-Small Cell Carcinoma Stage II Lung Cancer AJCC v8 Stage IIIA Lung Cancer AJCC v8 Stage IIIB Lung Cancer AJCC v8
Interventions
PROCEDURE DRUG OTHER BIOLOGICAL
No Results Yet
NCT04242563 | COMPLETED | NA
156 Participants

Virtual Reality for Preoperative Anxiety in Interventional Cardiology

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-02-02
Completion: 2021-07-12
Conditions
Anxiety
Interventions
OTHER
No Results Yet
NCT04200937 | ENROLLING_BY_INVITATION
450 Participants

IT Matters: The Erectile Restoration Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-08-05
Completion: 2031-01-31
Conditions
Erectile Dysfunction
Interventions
DEVICE
No Results Yet
NCT04179448 | ACTIVE_NOT_RECRUITING | NA
22 Participants

A Comparison of Side Access Mucosal Releasing Incision (SAMRI) and Sulcular Tunnel Access to Treat Gingival Recession.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-02-11
Completion: 2023-12-11
Conditions
Gingival Recession Lack of Keratinized Gingiva
Interventions
PROCEDURE
No Results Yet
NCT04165941 | ACTIVE_NOT_RECRUITING | PHASE1
22 Participants

Novel Gamma-Delta (γδ)T Cell Therapy for Treatment of Patients With Newly Diagnosed Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-02-11
Completion: 2026-12-31
Conditions
Brain Tumor Adult
Interventions
BIOLOGICAL
No Results Yet
NCT04155866 | COMPLETED
30 Participants

Comparing the Difference in Muscle Synergies Between Healthy Participants and Chronic Stroke Survivors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-07-01
Completion: 2025-12-01
Conditions
Healthy
Interventions
OTHER
No Results Yet
NCT04154514 | COMPLETED | NA
53 Participants

A Potential Wearable for Post-stroke Rehabilitation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-02-01
Completion: 2025-12-01
Conditions
Chronic Stroke
Interventions
DEVICE
No Results Yet
NCT04151667 | ACTIVE_NOT_RECRUITING | PHASE2
33 Participants

Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-11-22
Completion: 2023-11-08
Conditions
Multiple Myeloma
Interventions
DRUG
NCT04148911 | COMPLETED | PHASE3
184 Participants

A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-12-10
Completion: 2024-12-15
Conditions
Triple-Negative Breast Cancer
Interventions
DRUG
NCT04109586 | ACTIVE_NOT_RECRUITING | NA
56 Participants

Diet and Fat Mass After Traumatic Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-09-15
Completion: 2025-12-30
Conditions
Obesity Metabolic Disease Spinal Cord Injuries
Interventions
BEHAVIORAL
No Results Yet
NCT04099368 | COMPLETED | NA
120 Participants

Music Appreciation After Cochlear Implantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-10-01
Completion: 2025-01-01
Conditions
Hearing Loss Cochlear Implants
Interventions
BEHAVIORAL
No Results Yet
NCT04097145 | RECRUITING | NA
870 Participants

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-12-11
Completion: 2027-12-31
Conditions
Tricuspid Regurgitation Tricuspid Valve Insufficiency Tricuspid Valve Disease
Interventions
DEVICE DRUG
No Results Yet
NCT04090957 | COMPLETED | PHASE3
1015 Participants

Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort II)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-09-27
Completion: 2022-08-18
Conditions
Vasomotor Symptoms Menopausal Symptoms
Interventions
DRUG
NCT04075864 | COMPLETED | NA
3 Participants

Feasibility of a New Model for Exercise Prescription in Cystic Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-12-01
Completion: 2025-12-10
Conditions
Cystic Fibrosis
Interventions
BEHAVIORAL
No Results Yet
NCT04044443 | ACTIVE_NOT_RECRUITING
108 Participants

IMPEDE and IMPEDE-FX Embolization Plug Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2019-07-09
Completion: 2025-08-30
Conditions
Peripheral Vascular Embolization
Interventions
DEVICE
No Results Yet
NCT04041310 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
115 Participants

Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-10-21
Completion: 2026-10-30
Conditions
Solid Tumor, Adult
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT04014348 | RECRUITING
250 Participants

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-10-20
Completion: 2026-12-10
Conditions
Cardiovascular (CV) Risk
No Results Yet
NCT04009005 | ACTIVE_NOT_RECRUITING | NA
44 Participants

Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-05-01
Completion: 2022-08-01
Conditions
Clinically Isolated Syndrome Relapsing Remitting Multiple Sclerosis
Interventions
BEHAVIORAL
No Results Yet
NCT03995173 | ACTIVE_NOT_RECRUITING | PHASE2
1 Participants

Pilot rTMS for AUD+mTBI

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-03-21
Completion: 2026-03-31
Conditions
Alcohol Use Disorder Mild Traumatic Brain Injury Post-traumatic Stress Disorder
Interventions
DEVICE
No Results Yet
NCT03993379 | TERMINATED | PHASE2
3 Participants

PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-11-20
Completion: 2020-05-21
Conditions
Solid Tumor Unresectable or Metastatic Melanoma
Interventions
DRUG
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