IT Matters: The Erectile Restoration Registry

NCT ID: NCT04200937

Last Updated: 2025-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

450 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-05

Study Completion Date

2031-12-31

Brief Summary

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The objective of the It MATTERS registry is to collect Real-World Data (RWD) to monitor the safe and effective use of commercially available Boston Scientific Corporation (BSC) penile prostheses

Detailed Description

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IT MATTERS is a prospective, multicenter, observational registry that is part of planned, active post market clinical follow-up (PMCF) activity associated with each device.

The study will include adult males who undergo penile prothesis implantation with a market approved BSC device to treat erectile dysfunction.

Conditions

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Erectile Dysfunction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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BSC Penile Prothesis Recipients

Men for whom BSC Penile Prothesis is recommended.

Tactra Malleable

Intervention Type DEVICE

The Tactra™ Penile Prosthesis is a sterile, single-use implant that is intended for use in the treatment of chronic, organic, erectile dysfunction (impotence) in adult males who are suitable candidates for implantation procedure.

Spectra™ Concealable Penile Prothesis

Intervention Type DEVICE

The Spectra Penile Prothesis is a sterile, non-pyrogenic, single-use implant that is intended for use in the treatment of chronic, organic, erectile dysfunction (impotence) in men who are determined to be suitable candidates for implantation surgery.

AMS Ambicor™ Inflatable Penile Prosthesis

Intervention Type DEVICE

The AMS Ambicor inflatable penile prothesis intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence) in adult men who are determined to be suitable candidates for implantation surgery.

AMS 700™ Inflatable Penile Prosthesis w/Momentary Squeeze (MS) Pump

Intervention Type DEVICE

The AMS 700 Inflatable Penile Prosthesis is intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence).

AMS 700™ Inflatable Penile Prosthesis w/Tenacio™ Pump

Intervention Type DEVICE

The AMS 700 Inflatable Penile Prosthesis is intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence).

Interventions

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Tactra Malleable

The Tactra™ Penile Prosthesis is a sterile, single-use implant that is intended for use in the treatment of chronic, organic, erectile dysfunction (impotence) in adult males who are suitable candidates for implantation procedure.

Intervention Type DEVICE

Spectra™ Concealable Penile Prothesis

The Spectra Penile Prothesis is a sterile, non-pyrogenic, single-use implant that is intended for use in the treatment of chronic, organic, erectile dysfunction (impotence) in men who are determined to be suitable candidates for implantation surgery.

Intervention Type DEVICE

AMS Ambicor™ Inflatable Penile Prosthesis

The AMS Ambicor inflatable penile prothesis intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence) in adult men who are determined to be suitable candidates for implantation surgery.

Intervention Type DEVICE

AMS 700™ Inflatable Penile Prosthesis w/Momentary Squeeze (MS) Pump

The AMS 700 Inflatable Penile Prosthesis is intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence).

Intervention Type DEVICE

AMS 700™ Inflatable Penile Prosthesis w/Tenacio™ Pump

The AMS 700 Inflatable Penile Prosthesis is intended for use in the treatment of chronic, organic, male erectile dysfunction (impotence).

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. ≥ 18 years of age.
2. Males who are determined to be suitable candidates and scheduled to undergo surgical implantation of a market approved BSC penile prothesis by their physician.
3. Willing and able to complete the informed consent process.
4. Willing and able to comply with the follow-up requirements.

Exclusion Criteria

1. Males who are deemed by their physician as not suitable candidates for a penile prosthesis.
2. In the opinion of the investigator, it is not in best interest of the patient or the study for the patient to participate.
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mohit Khera, MD

Role: PRINCIPAL_INVESTIGATOR

Baylor College of Medicine

Locations

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USC Medical Center

Los Angeles, California, United States

Site Status

Ronald Reagan UCLA Medical Center

Los Angeles, California, United States

Site Status

Tower Urology-Research Facility

Los Angeles, California, United States

Site Status

University of Miami Hospital

Miami, Florida, United States

Site Status

USF Health South Tampa Center for Advanced Healthcare

Tampa, Florida, United States

Site Status

University of Chicago

Chicago, Illinois, United States

Site Status

SIU School of Medicine

Springfield, Illinois, United States

Site Status

Indiana University Medical Center

Indianapolis, Indiana, United States

Site Status

Willis-Knighton Medical Center

Bossier City, Louisiana, United States

Site Status

Washington University in St. Louis

St Louis, Missouri, United States

Site Status

Duke University Medical Center

Raleigh, North Carolina, United States

Site Status

W.G. Hefner VA Medical Center

Salisbury, North Carolina, United States

Site Status

Wake Forest University

Winston-Salem, North Carolina, United States

Site Status

Cleveland Clinic

Cleveland, Ohio, United States

Site Status

Ohio State University Wexner Medical Center

Columbus, Ohio, United States

Site Status

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, United States

Site Status

Baylor College of Medicine

Houston, Texas, United States

Site Status

Houston Methodist Hospital

Houston, Texas, United States

Site Status

University of Utah

Salt Lake City, Utah, United States

Site Status

University of Washington Medical Center

Seattle, Washington, United States

Site Status

Medical College of Wisconsin

Milwaukee, Wisconsin, United States

Site Status

Peking University First Hospital

Beijing, , China

Site Status

Shanghai General Hospital

Shanghai, , China

Site Status

Shanghai Jiaotong University School of Medicine Renji Hospital

Shanghai, , China

Site Status

Johns Hopkins Aramco Healthcare

Dhahran, , Saudi Arabia

Site Status

Countries

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United States China Saudi Arabia

Other Identifiers

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U0670

Identifier Type: -

Identifier Source: org_study_id