Clinical Trials
Showing trials with last updates posted in 2025.
2500
Participants
The Best Care for Abdominal Emergencies Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-01-08
Completion:
2022-05-01
Conditions
Acute Abdomen
Bowel Obstruction
Bowel; Ischemic, Acute
Bowel Perforated
Peritonitis
Interventions
PROCEDURE
No Results Yet
50
Participants
Auricular VNS Following Subarachnoid Hemorrhage
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-01-05
Completion:
2026-06-30
Conditions
Subarachnoid Hemorrhage
Interventions
DEVICE
No Results Yet
225
Participants
A Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Forimtamig in Participants With Relapsed or Refractory Multiple Myeloma (r/r MM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-11-11
Completion:
2026-02-20
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
60
Participants
Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-08-25
Completion:
2027-06-30
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
DRUG
BIOLOGICAL
No Results Yet
200
Participants
Neuronal Mechanisms of Human Episodic Memory
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-08-12
Completion:
2026-07-31
Conditions
Epilepsy Intractable
Interventions
BEHAVIORAL
No Results Yet
30
Participants
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2018-09-01
Completion:
2026-01-31
Conditions
Atherosclerosis
Stress
Inflammation
Interventions
BEHAVIORAL
No Results Yet
150
Participants
Ankle Instability Using Foot Intensive Rehabilitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-10-28
Completion:
2026-12-01
Conditions
Ankle Injuries
Ankle Sprains
Interventions
BEHAVIORAL
No Results Yet
240
Participants
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-07-14
Completion:
2027-06-01
Conditions
Cancer
Interventions
DRUG
No Results Yet
478
Participants
Sirolimus- vs. Paclitaxel-Drug Coated Ballons in Patients With Peripheral Artery Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-04-13
Completion:
2023-12-31
Conditions
Peripheral Artery Disease
Interventions
COMBINATION_PRODUCT
No Results Yet
12
Participants
Study of Tumor Treating Fields With Hypofractionated Chemoradiotherapy in Newly Diagnosed Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-05-21
Completion:
2024-11-14
Conditions
Glioblastoma
Newly Diagnosed Glioblastoma
Interventions
DEVICE
DRUG
RADIATION
No Results Yet
407
Participants
A Communication Tool to Assist Older Adults Facing Dialysis Choices
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-11-02
Completion:
2025-11-10
Conditions
Palliative Care
Kidney Failure, Chronic
Decision Making
Decision Support Techniques
Renal Dialysis
Dialysis
Kidney Diseases
Nephrologists
Decision Aid
End of Life
End-Stage Renal Disease
Late-Stage Renal Disease
Communication
Life-Supporting Treatments
Interventions
OTHER
No Results Yet
152
Participants
Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-10-08
Completion:
2027-03-31
Conditions
Early Stage Breast Cancer
Interventions
OTHER
No Results Yet
160
Participants
Reducing Stroke Risk in African-American Men
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-05-05
Completion:
2025-09-08
Conditions
Stroke
Transient Ischemic Attack
Interventions
BEHAVIORAL
No Results Yet
721
Participants
Genetics of COVID-19 Susceptibility and Manifestations
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-05-05
Completion:
2021-11-23
Conditions
COVID-19
Coronavirus 2019
No Results Yet
48995
Participants
Prevention of Colorectal Cancer Through Multiomics Blood Testing
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-05-20
Completion:
2024-02-29
Conditions
Colon Cancer
Rectal Cancer
Colon Neoplasm
Colon Diseases
Colon Lesion
Colon Polyp
Colorectal Cancer
Polyp
Adenoma
Rectal Diseases
Gastrointestinal Tract Cancers
Interventions
DIAGNOSTIC_TEST
500
Participants
The GErman Italian Spanish Takotsubo (GEIST) Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2015-04-30
Completion:
2035-12-31
Conditions
Takotsubo Syndrome
No Results Yet
39
Participants
Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2022-07-05
Completion:
2025-09-13
Conditions
Schizophrenia
Schizoaffective Disorder
Delusional Disorder
Major Depressive Disorder With Psychotic Features
Interventions
BEHAVIORAL
No Results Yet
66
Participants
Diaphragm Ultrasound Measurements With Variations in Modes of Ventilation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-02-05
Completion:
2022-04-11
Conditions
Mechanical Ventilation
Interventions
OTHER
No Results Yet
84
Participants
Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-09-10
Completion:
2027-12-31
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Interventions
DRUG
OTHER
No Results Yet
90
Participants
Ovarian Function Following Intraovarian Injection of PRP
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-02-24
Completion:
2026-07-31
Conditions
Diminished Ovarian Reserve
Diminished Ovarian Reserve Due to Advanced Maternal Age
Interventions
PROCEDURE
No Results Yet
1210
Participants
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-06-16
Completion:
2025-12-15
Conditions
Lung Non-Small Cell Carcinoma
Lung Non-Small Cell Squamous Carcinoma
Lung Non-Squamous Non-Small Cell Carcinoma
Stage II Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8
Interventions
PROCEDURE
DRUG
OTHER
BIOLOGICAL
No Results Yet
156
Participants
Virtual Reality for Preoperative Anxiety in Interventional Cardiology
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-02-02
Completion:
2021-07-12
Conditions
Anxiety
Interventions
OTHER
No Results Yet
450
Participants
IT Matters: The Erectile Restoration Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-08-05
Completion:
2031-01-31
Conditions
Erectile Dysfunction
Interventions
DEVICE
No Results Yet
22
Participants
A Comparison of Side Access Mucosal Releasing Incision (SAMRI) and Sulcular Tunnel Access to Treat Gingival Recession.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2021-02-11
Completion:
2023-12-11
Conditions
Gingival Recession
Lack of Keratinized Gingiva
Interventions
PROCEDURE
No Results Yet
22
Participants
Novel Gamma-Delta (γδ)T Cell Therapy for Treatment of Patients With Newly Diagnosed Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-02-11
Completion:
2026-12-31
Conditions
Brain Tumor Adult
Interventions
BIOLOGICAL
No Results Yet
30
Participants
Comparing the Difference in Muscle Synergies Between Healthy Participants and Chronic Stroke Survivors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-07-01
Completion:
2025-12-01
Conditions
Healthy
Interventions
OTHER
No Results Yet
53
Participants
A Potential Wearable for Post-stroke Rehabilitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-02-01
Completion:
2025-12-01
Conditions
Chronic Stroke
Interventions
DEVICE
No Results Yet
33
Participants
Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-11-22
Completion:
2023-11-08
Conditions
Multiple Myeloma
Interventions
DRUG
184
Participants
A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-12-10
Completion:
2024-12-15
Conditions
Triple-Negative Breast Cancer
Interventions
DRUG
56
Participants
Diet and Fat Mass After Traumatic Spinal Cord Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-09-15
Completion:
2025-12-30
Conditions
Obesity
Metabolic Disease
Spinal Cord Injuries
Interventions
BEHAVIORAL
No Results Yet
120
Participants
Music Appreciation After Cochlear Implantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-10-01
Completion:
2025-01-01
Conditions
Hearing Loss
Cochlear Implants
Interventions
BEHAVIORAL
No Results Yet
870
Participants
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-12-11
Completion:
2027-12-31
Conditions
Tricuspid Regurgitation
Tricuspid Valve Insufficiency
Tricuspid Valve Disease
Interventions
DEVICE
DRUG
No Results Yet
1015
Participants
Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort II)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-09-27
Completion:
2022-08-18
Conditions
Vasomotor Symptoms
Menopausal Symptoms
Interventions
DRUG
3
Participants
Feasibility of a New Model for Exercise Prescription in Cystic Fibrosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-12-01
Completion:
2025-12-10
Conditions
Cystic Fibrosis
Interventions
BEHAVIORAL
No Results Yet
108
Participants
IMPEDE and IMPEDE-FX Embolization Plug Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2019-07-09
Completion:
2025-08-30
Conditions
Peripheral Vascular Embolization
Interventions
DEVICE
No Results Yet
115
Participants
Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-10-21
Completion:
2026-10-30
Conditions
Solid Tumor, Adult
Interventions
BIOLOGICAL
DRUG
No Results Yet
250
Participants
Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2021-10-20
Completion:
2026-12-10
Conditions
Cardiovascular (CV) Risk
No Results Yet
44
Participants
Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2020-05-01
Completion:
2022-08-01
Conditions
Clinically Isolated Syndrome
Relapsing Remitting Multiple Sclerosis
Interventions
BEHAVIORAL
No Results Yet
1
Participants
Pilot rTMS for AUD+mTBI
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-03-21
Completion:
2026-03-31
Conditions
Alcohol Use Disorder
Mild Traumatic Brain Injury
Post-traumatic Stress Disorder
Interventions
DEVICE
No Results Yet
3
Participants
PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-11-20
Completion:
2020-05-21
Conditions
Solid Tumor
Unresectable or Metastatic Melanoma
Interventions
DRUG
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