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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07225504 | RECRUITING | PHASE3
1275 Participants

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-11
Completion: 2030-12-03
Conditions
Secondary Progressive Multiple Sclerosis (SPMS)
Interventions
DRUG
No Results Yet
NCT07225361 | RECRUITING | PHASE4
40 Participants

Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-28
Completion: 2029-03-15
Conditions
Multiple Sclerosis Multiple Sclerosis (MS) - Relapsing-remitting
Interventions
DRUG
No Results Yet
NCT07224477 | NOT_YET_RECRUITING | PHASE2
525 Participants

A Clinical Study of V540A in Healthy Female Participants (V540A-005)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-07-20
Completion: 2028-04-04
Conditions
Healthy
Interventions
BIOLOGICAL
No Results Yet
NCT07223593 | RECRUITING | PHASE3
1205 Participants

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-31
Completion: 2028-06-30
Conditions
Peripheral Arterial Disease
Interventions
DRUG
No Results Yet
NCT07223125 | RECRUITING | PHASE1
360 Participants

A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-10
Completion: 2026-12-15
Conditions
Advanced-stage Solid Tumors
Interventions
DRUG
No Results Yet
NCT07222605 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-12-24
No Results Yet
NCT07222475 | RECRUITING | NA
30 Participants

Writing Relaxing Beats in Adolescents Who Have Sickle Cell Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-05
Completion: 2026-07-31
Conditions
Sickle Cell Disease
Interventions
BEHAVIORAL
No Results Yet
NCT07222462 | RECRUITING | NA
300 Participants

A Superiority Trial of Radiofrequency Ablation for Low Back Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2029-03-31
Conditions
Chronic Low Back Pain (CLBP)
Interventions
PROCEDURE
No Results Yet
NCT07222358 | NOT_YET_RECRUITING
100 Participants

Multi-component Remote Assessment in Adult Survivors Using a Connected Technology Platform for Healthcare Delivery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2026-08-31
Conditions
Childhood Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT07222137 | NOT_YET_RECRUITING | PHASE3
150 Participants

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2031-07-31
Conditions
Diabetes Mellitus, Type 1
Interventions
DRUG
No Results Yet
NCT07221591 | RECRUITING | PHASE1
100 Participants

A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-05
Completion: 2026-08-24
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT07220824 | RECRUITING
200 Participants

A Study of Guselkumab in Participants With Psoriatic Arthritis (PsA) in a Real-World Setting

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-04
Completion: 2027-07-31
Conditions
Arthritis, Psoriatic
No Results Yet
NCT07220577 | RECRUITING | PHASE2
84 Participants

Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-10
Completion: 2027-05-24
Conditions
Atopic Dermatitis
Interventions
DRUG OTHER
No Results Yet
NCT07219966 | RECRUITING | PHASE3
1100 Participants

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-15
Completion: 2028-04-30
Conditions
Alcohol Use Disorder
Interventions
DRUG
No Results Yet
NCT07219550 | RECRUITING | PHASE1
58 Participants

A Study of MK-1084 in Participants With Hepatic Impairment and Healthy Volunteers (MK-1084-017)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-05
Completion: 2026-06-30
Conditions
Healthy Hepatic Impairment
Interventions
DRUG
No Results Yet
NCT07219212 | RECRUITING | PHASE1
30 Participants

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-11
Completion: 2028-07-14
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
DRUG RADIATION
No Results Yet
NCT07218393 | NOT_YET_RECRUITING
100 Participants

A Study About the Diagnosis and Management of Hereditary Angioedema (HAE) in Egypt

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2026-03-15
Completion: 2026-12-01
Conditions
Hereditary Angioedema (HAE)
Interventions
OTHER
No Results Yet
NCT07218367 | NOT_YET_RECRUITING | PHASE1
12 Participants

Phase I Trial of pH Resections of GBM at VA

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-02-01
Completion: 2031-02-01
Conditions
Glioblastoma
Interventions
PROCEDURE
No Results Yet
NCT07216482 | RECRUITING | PHASE3
975 Participants

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-11
Completion: 2026-12-02
Conditions
Hyperlipidemia
Interventions
DRUG
No Results Yet
NCT07216118 | NOT_YET_RECRUITING | NA
104 Participants

Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-04-30
Completion: 2028-04-30
Conditions
Diabetes in Adolescence Type 2 Diabetes Social Needs
Interventions
BEHAVIORAL
No Results Yet
NCT07215559 | RECRUITING | PHASE2
200 Participants

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-16
Completion: 2027-03-31
Conditions
Obesity Overweight Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT07214727 | RECRUITING | PHASE1
50 Participants

A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-15
Completion: 2030-03-31
Conditions
Alzheimer's Disease
Interventions
DRUG
No Results Yet
NCT07214233 | RECRUITING | NA
60 Participants

Youth Empowerment and Safety Intervention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2027-11-30
Conditions
Suicide Self-Injurious Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT07209657 | NOT_YET_RECRUITING | NA
10 Participants

Describing the Effect of Familiar Song on Arousal and Awareness for Children With Disorders of Consciousness (DoC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2028-11-30
Conditions
Disorder of Consciousness Acquired Brain Injury
Interventions
BEHAVIORAL
No Results Yet
NCT07209111 | RECRUITING | PHASE2
150 Participants

A Clinical Study of MK-1084 in People With Advanced Solid Tumors (MK-1084-014)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-04
Completion: 2032-04-09
Conditions
Neoplasm Malignant
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT07208409 | NOT_YET_RECRUITING | NA
60 Participants

Pleurodesis in Small-bore Chest Tube

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-02-01
Completion: 2027-01-31
Conditions
Pleural Effusion, Malignant
Interventions
DEVICE
No Results Yet
NCT07206472 | NOT_YET_RECRUITING
2560 Participants

A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-30
Completion: 2028-09-01
Conditions
Primary Hypercholesterolaemia Mixed Dyslipidemia
Interventions
DRUG
No Results Yet
NCT07202884 | RECRUITING | PHASE3
1000 Participants

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-09-30
Completion: 2028-03-31
Conditions
Urinary Incontinence,Stress
Interventions
DRUG
No Results Yet
NCT07198945 | NOT_YET_RECRUITING | NA
546 Participants

Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2029-07-31
Conditions
Colon Cancer Colon Polyp Adenoma Serrated Polyp Recurrence, Local Neoplasm Endoscopic Resection
Interventions
PROCEDURE
No Results Yet
NCT07198334 | COMPLETED | NA
26 Participants

The Effect of Daily Brief Heat Exposures on Heat Acclimation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2020-10-01
Completion: 2024-05-31
Conditions
Healthy Participants
Interventions
OTHER
No Results Yet
NCT07198100 | RECRUITING | NA
120 Participants

tVNS, Motivation, and Insulin Sensitivity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-10
Completion: 2027-12-31
Conditions
Major Depressive Disorder (MDD)
Interventions
DEVICE DIAGNOSTIC_TEST
No Results Yet
NCT07197827 | RECRUITING | PHASE1/PHASE2
424 Participants

A Study of YL242 in Subjects With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-09-22
Completion: 2028-09-30
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT07194200 | RECRUITING | PHASE2
184 Participants

Safety and Efficacy of Lactobacillus Plantarum for Psoriasis: A Randomized Double-Blind Placebo-Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-15
Completion: 2026-06-25
Conditions
Psoriasis Lactobacillus Plantarum
Interventions
BIOLOGICAL
No Results Yet
NCT07192939 | RECRUITING | PHASE2
270 Participants

Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Trial to Evaluate the Efficacy and Safety of HRS-9813 in Subjects With Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-29
Completion: 2028-06-30
Conditions
IPF and PPF
Interventions
DRUG
No Results Yet
NCT07190248 | RECRUITING | PHASE3
675 Participants

A Clinical Study of MK-1084 and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-08
Completion: 2029-12-07
Conditions
Non-small Cell Lung Cancer
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT07189676 | RECRUITING | NA
180 Participants

Sustainable Diets and Cardiometabolic Health

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-24
Completion: 2027-04-30
Conditions
Cardiometabolic Diseases
Interventions
BEHAVIORAL
No Results Yet
NCT07187115 | RECRUITING | NA
699 Participants

A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-07
Completion: 2028-07-31
Conditions
Atrial Fibrillation (AF) Persistant Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT07180875 | NOT_YET_RECRUITING | NA
60 Participants

"Hypoxic vs. Aerobic Training in Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-09
Completion: 2026-01-15
Conditions
Chronic Kidney Disease (CKD), Stages 3-4 Exercise Tolerance / Functional Capacity Vascular Health / Arterial Stiffness Fatigue in CKD
Interventions
BEHAVIORAL
No Results Yet
NCT07180004 | COMPLETED
70 Participants

Upper Extremity Functional Skills in Patients With Parkinson Disease (pwPD)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-01-01
Completion: 2025-12-15
Conditions
PARKINSON DISEASE (Disorder) Upper Extremity Muscle Strength Development Functional Skills
No Results Yet
NCT07175441 | RECRUITING | PHASE2
220 Participants

Evaluation of RBS2418 in Combination With Tremelimumab Plus Durvalumab in Participants With Advanced Unresectable Hepatocellular Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2027-04-30
Conditions
Advanced Unresectable Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
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