Clinical Trials Updated in 2025

NCT07097012 | RECRUITING | PHASE4

60 Participants

Concurrent Versus Sequential Administration of Tdap and RSV Vaccines in Pregnancy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-16

Completion: 2026-01-31

Conditions

RSV Tdap - Tetanus, Diphtheria and Acellular Pertussis Vaccination Pregnancy Healthy

Interventions

BIOLOGICAL OTHER

No Results Yet

NCT07091071 | RECRUITING | NA

73 Participants

Evaluation of the CochSyn Device in Clinical Practice

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-29

Completion: 2025-12-31

Conditions

Hearing Loss, Sensorineural Cochlear Hearing Loss Cochlear Synaptopathy DFNA9

Interventions

DEVICE

No Results Yet

NCT07086976 | RECRUITING | PHASE3

90 Participants

A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-08-18

Completion: 2028-05-31

Conditions

Autoimmune Haemolytic Anaemia

Interventions

DRUG

No Results Yet

NCT07085754 | RECRUITING | NA

60 Participants

Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-08-08

Completion: 2025-12-31

Conditions

Sleep Sleep Deprivation

Interventions

BEHAVIORAL

No Results Yet

NCT07085442 | RECRUITING

200 Participants

Audit of Targeted Sentinel Node Biopsy (TSNB) in Patients With Limited Nodal Disease Undergoing Primary Surgery

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-01-17

Completion: 2032-12-31

Conditions

Breast Cancer Axillary Lymph Nodes Dissection Axillary Metastases Sentinel Lymph Node Biopsy (SLNB) Node Positive Breast Cancer Axilla; Breast Axillary Ultrasound

Interventions

PROCEDURE

No Results Yet

NCT07082829 | RECRUITING | PHASE1

208 Participants

A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-06-30

Completion: 2026-06-15

Conditions

Excessive Daytime Sleepiness

Interventions

DRUG OTHER

No Results Yet

NCT07081880 | RECRUITING

100 Participants

Study of the Pathophysiological Mechanisms Involved in the SAPHO Syndrome: Genetic Component and Immune Response

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-07-15

Completion: 2028-07-15

Conditions

SAPHO Syndrome

Interventions

OTHER

No Results Yet

NCT07080853 | COMPLETED | NA

23 Participants

Acute Exercise With Overdressing

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2023-06-22

Completion: 2025-04-28

Conditions

Heat Stress, Exertional Heat Acclimation and Thermotolerance

Interventions

OTHER

No Results Yet

NCT07079475 | RECRUITING | PHASE1/PHASE2

200 Participants

Study of Oral EGFR Inhibitor DZD6008 Combined With Sunvozertinib in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN8)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-07-31

Completion: 2028-12-31

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07079462 | RECRUITING | PHASE2

40 Participants

Comparing 68Ga-FAPI PET-Guided Abdominal Radiotherapy Combined With Second-Line Standard Therapy and Cadonilimab Versus Second-Line Standard Therapy in Colorectal Cancer With Peritoneal Metastasis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2024-03-01

Completion: 2026-03-01

Conditions

Colorectal Cancer Peritoneal (Metastatic) Cancer FAPI PET

Interventions

COMBINATION_PRODUCT DRUG

No Results Yet

NCT07075861 | RECRUITING

75 Participants

The ARTEMIS Data Collection Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-08-10

Completion: 2028-08-10

Conditions

Aortic Regurgitation Disease

No Results Yet

NCT07074756 | RECRUITING | NA

120 Participants

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-09-12

Completion: 2028-08-31

Conditions

Glioma Recurrent Glioma

Interventions

DRUG PROCEDURE OTHER BEHAVIORAL

No Results Yet

NCT07069725 | RECRUITING | PHASE1

12 Participants

The Phase 1, Open-label, PET Trial Designed to Investigate the Effect of AZD2389 on FAP Occupancy in the Liver in Participants With Advanced Liver Fibrosis.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-05-26

Completion: 2026-03-31

Conditions

Liver Fibrosis Hepatic Cirrhosis

Interventions

DRUG DIAGNOSTIC_TEST

No Results Yet

NCT07069400 | RECRUITING

1500 Participants

An International Observational Study of Adults With Acute Infection

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-08-25

Completion: 2027-06-08

Conditions

Infectious Disease

Interventions

OTHER

No Results Yet

NCT07063589 | RECRUITING

350 Participants

Cannabis Use Patterns Among Young Adults and Associations With Social and Health Outcomes.

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-09-16

Completion: 2027-08-31

Conditions

Cannabis Use

Interventions

OTHER

No Results Yet

NCT07061925 | COMPLETED | PHASE2

169 Participants

To Evaluate the Efficacy and Safety of ALC-2203 in Patients With Acute Bronchitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-04-23

Completion: 2025-11-21

Conditions

Acute Bronchitis

Interventions

DRUG

No Results Yet

NCT07060807 | RECRUITING | PHASE3

1000 Participants

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-07-21

Completion: 2033-07-14

Conditions

Breast Neoplasms

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT07046546 | RECRUITING | NA

10 Participants

Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-09-29

Completion: 2026-11-30

Conditions

Thyroid Nodule (Benign) Graves Disease Goitre

Interventions

PROCEDURE

No Results Yet

NCT07040722 | RECRUITING | NA

12 Participants

Effects of the Use of an Immersive Virtual Reality Device on Handwriting in Children Aged 6 to 13 With Handwriting Difficulties ( RVALIGO )

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-01

Completion: 2027-09-01

Conditions

Children With a Need of Rehabilitation for Handwriting

Interventions

OTHER

No Results Yet

NCT07038902 | ACTIVE_NOT_RECRUITING | NA

24 Participants

A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-01

Completion: 2026-12-01

Conditions

Malocclusion, Class I/II Crowding Maxillary First Molar Distalization

Interventions

DEVICE

No Results Yet

NCT07036081 | RECRUITING | NA

40 Participants

A Single Arm Intervention Study to Assess the Acceptability, Tolerance and Ease of Use of Wilbo's Blends+ (Commercial Enteral Feed Based on Real Food) When Used as Part of a Dietitian Prescribed Enteral Feeding Plan

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-16

Completion: 2026-03-30

Conditions

Enteral Nutrition (Food for Special Medical Purposes) Enteral Feeds Enteral Tube Nutrition Gastrostomy Tube

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07034469 | NOT_YET_RECRUITING | NA

150 Participants

Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal Detachment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-03-20

Completion: 2029-03-20

Conditions

Retinal Detachment Rhegmatogenous

Interventions

PROCEDURE

No Results Yet

NCT07033494 | RECRUITING | PHASE2

340 Participants

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-07-16

Completion: 2029-04-30

Conditions

Early Alzheimer's Disease

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT07033416 | RECRUITING | NA

60 Participants

A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-03-31

Completion: 2026-10-31

Conditions

Training for Cocaine Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07031934 | COMPLETED

114 Participants

Investigation of the Relationships Between Core Muscle Endurance, Pelvic Oscillations and Pelvic Width in Athletes and Sedentaries

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-06-25

Completion: 2025-06-30

Conditions

Core Muscle Endurance Athlete Sedentary

No Results Yet

NCT07030517 | RECRUITING | PHASE4

75 Participants

A Study to Assess Safety of Teclistamab in Indian Participants With Relapsed and Refractory Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-05-22

Completion: 2026-11-03

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT07029191 | COMPLETED | NA

12 Participants

Screening for Alterations in the Autonomic Nervous System

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-21

Completion: 2025-12-12

Conditions

Dysautonomia ACCUVEIN Superficial Veins Sympathetic Nervous System Standing Test

Interventions

OTHER

No Results Yet

NCT07027891 | RECRUITING | NA

4670 Participants

The Rule-Out Acute Myocardial Infarction Using Aritifical Intelligence Electrocardiogram (ROMIAE) 2 Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-07-01

Completion: 2027-12-30

Conditions

Myocardial Infarction (MI) Chest Pain Rule Out Myocardial Infarction

Interventions

DEVICE

No Results Yet

NCT07025720 | RECRUITING | NA

25 Participants

Personalized Accelerated TMS for High-Risk Adolescent Depression

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-07-01

Completion: 2027-04-30

Conditions

Suicidal Ideation Major Depressive Disorder (MDD)

Interventions

DEVICE

No Results Yet

NCT07025538 | RECRUITING | PHASE1

42 Participants

Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-09

Completion: 2028-04-05

Conditions

Hematopoietic and Lymphatic System Neoplasm

Interventions

OTHER PROCEDURE DRUG

No Results Yet

NCT07024498 | NOT_YET_RECRUITING | NA

3492 Participants

Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-01

Completion: 2029-05-01

Conditions

Opioid Use Disorder

Interventions

OTHER

No Results Yet

NCT07024316 | RECRUITING | PHASE1/PHASE2

6 Participants

A Study to Investigate the Improvement of Photosensitivity in Terms of Skin Lesions Associated With CEP Following Administration of Oral ATL-001 (Ciclopirox Oral Solution) in Participants Aged >18 Years of Age With CEP

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-15

Completion: 2027-10-01

Conditions

Congenital Erythropoietic Porphyria (CEP)

Interventions

DRUG

No Results Yet

NCT07023302 | RECRUITING | PHASE3

123 Participants

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia Areata

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-06-19

Completion: 2029-02-28

Conditions

Alopecia Areata

Interventions

DRUG

No Results Yet

NCT07020520 | RECRUITING | NA

60 Participants

EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-01

Completion: 2027-02-28

Conditions

Ureteral Stricture

Interventions

DEVICE

No Results Yet

NCT07018856 | RECRUITING

120 Participants

Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-09-16

Completion: 2026-09-30

Conditions

Pneumothorax Cardiac Surgery Lung Ultrasound Chest Tube Removal Postoperative Complications (Cardiopulmonary)

No Results Yet

NCT07018596 | NOT_YET_RECRUITING | NA

215 Participants

NS-PFA Catheter Ablation of Paroxysmal Atrial Fibrillation With the Pulse Biosciences CellFX System

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-31

Completion: 2026-10-31

Conditions

Atrial Fibrillation Paroxysmal Cardiac Ablation Cardiac Arrhythmia

Interventions

DEVICE

No Results Yet

NCT07005050 | RECRUITING | NA

60 Participants

Renal Pelvic Denervation Pilot Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-30

Completion: 2026-10-30

Conditions

Uncontrolled Hypertension

Interventions

DEVICE DRUG

No Results Yet

NCT07003919 | RECRUITING | PHASE3

480 Participants

Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-06-24

Completion: 2026-11-30

Conditions

Allergy Peanut Allergy

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07001475 | RECRUITING | PHASE1

96 Participants

A Study to Test How BI 3031185 is Tolerated by People With Borderline Personality Disorder or Attention-deficit/Hyperactivity Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-08-12

Completion: 2026-04-27

Conditions

Borderline Personality Disorder Attention Deficit Hyperactivity Disorder

Interventions

DRUG

No Results Yet

NCT07001319 | RECRUITING | PHASE1

30 Participants

Study of GS-3242 in Participants With HIV-1; Substudy-05

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-05-29

Completion: 2025-12-31

Conditions

HIV-1-infection

Interventions

DRUG

No Results Yet