Clinical Trials
Showing trials with last updates posted in 2025.
75
Participants
A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-27
Completion:
2027-03-30
Conditions
Von Willebrand Disease, Type 3
Interventions
DRUG
No Results Yet
40
Participants
Characterization of Placental Diffusion
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-07-06
Completion:
2027-12-31
Conditions
Pregnancy in Diabetic
Placenta Diseases
Interventions
DIAGNOSTIC_TEST
No Results Yet
132
Participants
Effects of Different Irrigation Activation Techniques on the Healing of Large Periapical Lesions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-06-01
Completion:
2024-06-30
Conditions
Periapical Periodontitis
Irrigation Activation
Lasers
Interventions
OTHER
90
Participants
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-09
Completion:
2028-01-31
Conditions
Refractory Rheumatoid Arthritis (RA)
Idiopathic Inflammatory Myopathies (IIMs)
Systemic Sclerosis (SSc)
Rheumatoid Arthritis (RA
IIM
Myositis
Scleroderma
Sjogren Syndrome
Sjogrens Disease
Interventions
DRUG
No Results Yet
250
Participants
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-08-11
Completion:
2027-11-04
Conditions
Malignant Neoplasm
Interventions
DRUG
No Results Yet
116
Participants
Ear Pressure Points Plus Pain Meds for Faster Kidney Stone Pain Relief
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-01
Completion:
2025-12-30
Conditions
Renal Colic
Acupuncture, Ear
Interventions
DRUG
OTHER
No Results Yet
40
Participants
Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-02-01
Completion:
2026-10-15
Conditions
Psychiatric Disorder
Interventions
PROCEDURE
OTHER
BEHAVIORAL
No Results Yet
108
Participants
Does the TAP Block Work Better Than the TFP Block for Relieving Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-25
Completion:
2025-12-15
Conditions
Pain
Interventions
PROCEDURE
No Results Yet
365
Participants
Aerodynamic Measurements in the Pediatric Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-22
Completion:
2030-12-31
Conditions
Normal Voice
Interventions
DEVICE
No Results Yet
40
Participants
Prevalence and Description of FIRE (Food Induced Immediate Response of the Esophagus) in the Pediatric Population With Eosinophilic Esophagitis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-01
Completion:
2026-05-01
Conditions
Eosinophilic Esophagitis
No Results Yet
46
Participants
Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-02-01
Completion:
2027-04-01
Conditions
Delirium
Surgery-Complications
Interventions
DRUG
No Results Yet
24
Participants
Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-30
Completion:
2028-05-30
Conditions
Advanced Hepatocellular Carcinoma
Metastatic Hepatocellular Carcinoma
Recurrent Hepatocellular Carcinoma
Refractory Hepatocellular Carcinoma
Stage III Hepatocellular Carcinoma AJCC v8
Stage IV Hepatocellular Carcinoma AJCC v8
Interventions
BIOLOGICAL
PROCEDURE
DRUG
No Results Yet
2400
Participants
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-30
Completion:
2033-03-23
Conditions
Breast Neoplasms
Triple Negative Breast Neoplasms
HR Low-Positive/HER2-Negative Breast Neoplasms
Interventions
BIOLOGICAL
DRUG
No Results Yet
150
Participants
Hold me Tight/Let me Go: Effectiveness of a Course to Enhance Parent-adolescent Relationship
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-11
Completion:
2028-02-01
Conditions
Parent Training
Parent Child Relationship
Parent-child Problem
Interventions
BEHAVIORAL
No Results Yet
80
Participants
Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel (XCMIM20m) Assessed by PROMs.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-08
Completion:
2024-12-17
Conditions
Vulvar Atrophy
Vulvovaginal Signs and Symptoms
Genitourinary Syndrome of Menopause
Quality of Life
Menopause Related Conditions
Dyspareunia
Urinary Incontinence, Urgency-frequency
Sexual Function
Women´s Health
Vaginal Dryness
Interventions
DEVICE
No Results Yet
465
Participants
A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-12
Completion:
2027-04-30
Conditions
Type 1 Diabetes
Obesity
Overweight
Interventions
DRUG
No Results Yet
487
Participants
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-30
Completion:
2027-09-30
Conditions
Hypertension
Interventions
DRUG
No Results Yet
1123
Participants
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-22
Completion:
2032-05-24
Conditions
Endometrial Cancer
Interventions
BIOLOGICAL
DRUG
No Results Yet
487
Participants
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-30
Completion:
2027-09-30
Conditions
Hypertension
Overweight or Obesity
Interventions
DRUG
No Results Yet
201
Participants
A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-23
Completion:
2026-04-30
Conditions
Healthy
Overweight
Obesity
Type 2 Diabetes
Interventions
DRUG
No Results Yet
666
Participants
Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-09-01
Completion:
2028-09-01
Conditions
Dental Caries
Dental Cavities
Interventions
PROCEDURE
No Results Yet
142
Participants
Integrating SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-24
Completion:
2025-12-18
Conditions
Disease and Dysfunction
Functional Fitness Deterioration
Activities of Daily Living
Instrumental Activities of Daily Living
Sleep Quality
Interventions
OTHER
No Results Yet
680
Participants
Effectiveness of Integrated Network for Student Psychosocial Intervention, Resilience, and Education (INSPIRE) on Mental Health Outcomes Among Indonesian Adolescents in Bandung
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-28
Completion:
2026-02-16
Conditions
Adolescents
Health Knowledge
Mental Health
Health Literacy
Resilience
Depression
Anxiety
Parents
School Intervention
Interventions
BEHAVIORAL
No Results Yet
40
Participants
Comparison of Two Gait Re-training Modalities During a Cardiac Rehabilitation Stay: Benefit of Orienteering Walking
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-28
Completion:
2025-10-05
Conditions
Cardiovascular Diseases (CVD)
Coronary Heart Disease (CHD)
Heart Failure
Congenital Heart Disease
No Results Yet
142
Participants
Using SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-23
Completion:
2025-12-18
Conditions
Cognitive and Behavioral Impairment
Sensory and Perceptual Impairment
Interventions
OTHER
No Results Yet
50
Participants
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-26
Completion:
2030-12-30
Conditions
Malignant Neoplasm
Interventions
BIOLOGICAL
No Results Yet
30
Participants
Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-01
Completion:
2026-07-31
Conditions
Diabetic Foot Ulcers (DFUs)
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Interventions
DEVICE
OTHER
No Results Yet
20
Participants
Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-29
Completion:
2025-12-31
Conditions
Diabetic Foot Ulcers (DFUs)
Venous Leg Ulcers (VLUs)
Pressure Ulcers
Surgical Wound Dehiscence (SWD)
Chronic Wounds
Undermined and Tunneling Wounds
Interventions
DEVICE
No Results Yet
An Expanded Access Study to Assess Treprostinil Palmitil Inhalation Powder (TPIP) for Participants With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-24
Conditions
Pulmonary Arterial Hypertension
Pulmonary Hypertension, Interstitial Lung Disease
Interventions
DRUG
No Results Yet
1440
Participants
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-13
Completion:
2028-06-26
Conditions
Prostate Cancer
Prostatic Neoplasms
Interventions
DRUG
No Results Yet
16
Participants
Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-31
Completion:
2025-09-19
Conditions
Glucose Metabolism
Glucagon
Interventions
OTHER
No Results Yet
42
Participants
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-09
Completion:
2027-11-30
Conditions
Metabolic Dysfunction-Associated Steatohepatitis
Interventions
DRUG
No Results Yet
92
Participants
FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-05
Completion:
2028-03-31
Conditions
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Interventions
DRUG
No Results Yet
72
Participants
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-01
Completion:
2027-06-22
Conditions
Systemic Lupus Erythematosus
Idiopathic Inflammatory Myopathies
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
905
Participants
A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-25
Completion:
2027-05-31
Conditions
Type 1 Diabetes
Obesity
Overweight
Interventions
DRUG
No Results Yet
60
Participants
Safety of a Single, Intravitreal Injection of 8.8M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-20
Completion:
2026-09-30
Conditions
Retinitis Pigmentosa
Interventions
BIOLOGICAL
OTHER
No Results Yet
6000
Participants
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-23
Completion:
2029-10-31
Conditions
Percutaneous Coronary Intervention
Peripheral Endovascular Intervention
Interventions
DRUG
No Results Yet
240
Participants
A Study to Assess Adverse Events and Effectiveness of IntraVenous Infusions of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-09
Completion:
2029-08-31
Conditions
Autosomal Dominant Polycystic Kidney Disease
Interventions
DRUG
No Results Yet
100
Participants
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-04
Completion:
2025-08-01
Conditions
Intra-Abdominal Infections
Intestinal Obstruction
Appendicitis Acute
Perforated Viscus
240
Participants
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-28
Completion:
2026-12-31
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
Showing 40 trials per page