Clinical Trials
Showing trials with last updates posted in 2025.
51
Participants
Venetoclax and Azacitidine for the Treatment of High-Risk Recurrent or Refractory Myelodysplastic Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-10-01
Completion:
2027-12-31
Conditions
Chronic Myelomonocytic Leukemia
Myelodysplastic Syndrome
Recurrent Myelodysplastic Syndrome
Refractory Myelodysplastic Syndrome
Therapy-Related Myelodysplastic Syndrome
Interventions
DRUG
No Results Yet
7
Participants
Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-02-19
Completion:
2024-11-11
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
30
Participants
Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-10-21
Completion:
2027-06-30
Conditions
Pancreatic Cancer
Pancreatic Neoplasms
Pancreatic Ductal Adenocarcinoma
Advanced Cancer
Interventions
DRUG
BIOLOGICAL
No Results Yet
400
Participants
The Effect of IoT-based Smart Exercises System in the Senior Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-07-15
Completion:
2027-08-31
Conditions
Elderly Exercise
Interventions
DEVICE
No Results Yet
56
Participants
A Study of WVT078 in Patients With Multiple Myeloma (MM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-12-05
Completion:
2024-12-02
Conditions
Multiple Myeloma (MM)
Interventions
BIOLOGICAL
DRUG
No Results Yet
58
Participants
A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-02-12
Completion:
2026-04-30
Conditions
Systemic Juvenile Idiopathic Arthritis
Interventions
DRUG
No Results Yet
Intermediate Expanded Access Protocol CNMAu8.EAP03
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-24
Conditions
Multiple Sclerosis
Interventions
DRUG
No Results Yet
701
Participants
A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-09-04
Completion:
2026-06-03
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
10
Participants
Passport to Freedom (P2F): Adaptation and Implementation of a Wellness Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-10-28
Completion:
2021-10-23
Conditions
Trauma
Interventions
BEHAVIORAL
No Results Yet
32
Participants
OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-11-04
Completion:
2026-12-31
Conditions
Liver Metastases
Stereotactic Body Radiation Therapy
MRI-guided Treatment
Interventions
RADIATION
No Results Yet
28
Participants
Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-09-24
Completion:
2026-08-31
Conditions
Pancreatic Cancer
Interventions
DRUG
RADIATION
No Results Yet
32
Participants
Neural Control of Kidney Blood Flow During Exercise in African American Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-09-30
Completion:
2026-04-30
Conditions
Healthy
Interventions
OTHER
No Results Yet
94
Participants
A Preoperative Cognitive Behavioural Therapy Program Based on Self-determination Theory for Bariatric Surgery Candidates
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-02-05
Completion:
2020-09-05
Conditions
Bariatric Surgery Candidate
Obesity
Interventions
BEHAVIORAL
No Results Yet
200
Participants
A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-06-03
Completion:
2021-08-31
Conditions
Generalized Myasthenia Gravis
Interventions
DRUG
OTHER
692
Participants
Patient-Centered Assessment of Symptoms and Outcomes
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-09-13
Completion:
2026-06-01
Conditions
Sjogrens
Fatigue
Cancer
CFS
ME/CFS
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Lupus
Systemic Lupus Erthematosus
No Results Yet
2000
Participants
Collection of Bone Marrow Aspirate From Normal Volunteers
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-05-08
Completion:
2050-12-31
Conditions
Normal Aging
No Results Yet
30
Participants
C-Brace II Spinal Cord Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-04-16
Completion:
2026-11-30
Conditions
Spinal Cord Injury
Interventions
DEVICE
No Results Yet
332
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-04-25
Completion:
2021-09-03
Conditions
Ankylosing Spondylitis
Interventions
DRUG
OTHER
274
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Nonradiographic Axial Spondyloarthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-04-25
Completion:
2022-06-29
Conditions
Nonradiographic Axial Spondyloarthritis
Interventions
DRUG
OTHER
50
Participants
Recognition of Circulating Tumor DNA in Soft Tissue Sarcoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-06-18
Completion:
2026-06-01
Conditions
Sarcoma
Interventions
DEVICE
DRUG
OTHER
No Results Yet
170
Participants
Real World Study of Biosimilar Trastuzumab in Her2 Positive Breast Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-10-07
Completion:
2022-12-30
Conditions
Breast Cancer
No Results Yet
450
Participants
Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-04-01
Completion:
2024-06-28
Conditions
Carcinoma, Squamous Cell
Interventions
BIOLOGICAL
DRUG
112
Participants
Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-03-08
Completion:
2021-02-11
Conditions
Hypertriglyceridemia
Familial Chylomicronemia
Interventions
DRUG
No Results Yet
140
Participants
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-11-19
Completion:
2030-11-08
Conditions
Malignant Solid Neoplasm
Metastatic Malignant Neoplasm in the Brain
Interventions
PROCEDURE
OTHER
RADIATION
No Results Yet
93
Participants
Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-01-07
Completion:
2021-05-17
Conditions
Dyslipidemias
Familial Hypercholesterolemia
Hypertriglyceridemia
Interventions
DRUG
No Results Yet
43
Participants
NEO-SPACE Trial: Pembrolizumab and Chemoradiation in Nasopharyngeal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-05-03
Completion:
2025-01-25
Conditions
NPC
Interventions
DRUG
75
Participants
Ibrutinib + R-CHOP Followed by Ibrutinib Maintenance
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-07-02
Completion:
2024-07-30
Conditions
DLBCL
Interventions
DRUG
No Results Yet
104
Participants
Geriatric Acetabular fracTures: Open Reduction Internal Fixation Versus Replacement
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-31
Completion:
2029-12-31
Conditions
Acetabular Fracture
No Results Yet
17
Participants
Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-03-20
Completion:
2025-10-06
Conditions
Burns
Hypertrophic Scar
Interventions
PROCEDURE
No Results Yet
23
Participants
TAS 102 in Combination With Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-12-20
Completion:
2022-01-19
Conditions
Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Gastric Cancer
Interventions
DRUG
46
Participants
Transpyloric Feeding for Prevention of Micro-aspiration
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2016-11-04
Completion:
2018-05-30
Conditions
Microaspiration
Gastro Esophageal Reflux
Interventions
OTHER
No Results Yet
102
Participants
Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-10-24
Completion:
2026-05-01
Conditions
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Chronic Myelomonocytic Leukemia (CMML)
MDS/Myeloproliferative Neoplasm-unclassifiable (MDS/MPN-unclassifiable)
Hematopoietic Stem Cell Transplant
Interventions
DRUG
No Results Yet
131
Participants
Spinal Pain and Autonomic Responses to Chiropractic Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-01-04
Completion:
2020-05-02
Conditions
Neck Pain
Interventions
OTHER
5
Participants
Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-05-31
Completion:
2023-05-16
Conditions
Chronic Lymphocytic Leukemia
Interventions
DRUG
250
Participants
Healthy People Initiative (HPI)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-01-03
Completion:
2027-03-31
Conditions
Nicotine Dependence
Substance Use Disorders
Interventions
BEHAVIORAL
No Results Yet
51
Participants
High-Flow Nasal Oxygen Therapy for Exacerbation of Chronic Pulmonary Obstructive Disease.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-06-27
Completion:
2025-10-03
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
OTHER
No Results Yet
3500
Participants
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-08-21
Completion:
2043-08-04
Conditions
Solid Tumors
Hematologic Malignancies
Interventions
DRUG
BIOLOGICAL
No Results Yet
120
Participants
Effectiveness of Contrast-Enhanced Ultrasound
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-05-09
Completion:
2026-12-31
Conditions
Abdominal Injuries
Physical Abuse
Accidental Fall
Motor Vehicle Injury
Interventions
DRUG
No Results Yet
25
Participants
A Study of Venetoclax and Rituximab/Hyaluronidase Human in Relapsed/Refractory CLL
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-04-26
Completion:
2026-12-31
Conditions
Chronic Lymphocytic Leukemia
Interventions
DRUG
No Results Yet
8
Participants
Hyperbaric Oxygen Therapy in Sickle Cell Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-09-01
Completion:
2025-06-05
Conditions
Vaso-occlusive Crisis
Sickle Cell Anemia Crisis
Interventions
DEVICE
No Results Yet
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