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Clinical Trials

Showing trials with last updates posted in 2025.

NCT03406208 | COMPLETED | NA
228 Participants

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-10-01
Completion: 2022-02-28
Conditions
Neurofibromatoses Neurofibromatosis 1 Neurofibromatosis 2 Schwannomatosis
Interventions
BEHAVIORAL
No Results Yet
NCT03394066 | RECRUITING | NA
70 Participants

Mechanism of Non-invasive Magnetic Stimulation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2018-09-19
Completion: 2026-12-31
Conditions
Healthy Volunteers
Interventions
DEVICE
No Results Yet
NCT03362242 | COMPLETED | PHASE1
45 Participants

Study of ARO-AAT in Normal Adult Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2018-03-12
Completion: 2018-10-23
Conditions
Alpha 1-Antitrypsin Deficiency
Interventions
DRUG OTHER
No Results Yet
NCT03351764 | COMPLETED | NA
83 Participants

Development of Non-Invasive Brain Stimulation Techniques

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2018-01-11
Completion: 2025-12-15
Conditions
Normal Physiology
Interventions
DEVICE
No Results Yet
NCT03348280 | ACTIVE_NOT_RECRUITING
40 Participants

Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2017-09-01
Completion: 2026-12-31
Conditions
Diabetes Mellitus, Type 2 Hypertension Vitamin D Deficiency
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03294863 | ACTIVE_NOT_RECRUITING | NA
12 Participants

Effectiveness of Embrace Scar Therapy Device After Cutaneous Wound Closure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-03-15
Completion: 2021-12-01
Conditions
Linear Cutaneous Wound
Interventions
DEVICE OTHER
No Results Yet
NCT03269721 | COMPLETED
170 Participants

COPD-Related Physiology and the Brain

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2017-05-01
Completion: 2025-04-30
Conditions
Pulmonary Disease, Chronic Obstructive (COPD) Cognitive Impairment
Interventions
BEHAVIORAL PROCEDURE DIAGNOSTIC_TEST BIOLOGICAL
No Results Yet
NCT03261089 | RECRUITING
600 Participants

Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2017-08-02
Completion: 2027-08-31
Conditions
Cardiac Arrest
No Results Yet
NCT03111745 | COMPLETED
730 Participants

Retrospective Study of Viral Reactivation Across All Bone Marrow Transplant Protocols Since 2010

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2017-04-13
Completion: 2018-12-29
Conditions
Viral Infections
No Results Yet
NCT03091452 | RECRUITING
2000 Participants

CArdioSurgEry Atrial Fibrillation Register

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2017-01-31
Completion: 2028-12-31
Conditions
Atrial Fibrillation
No Results Yet
NCT03076554 | ACTIVE_NOT_RECRUITING | PHASE2
56 Participants

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-04-19
Completion: 2026-06-30
Conditions
Thymoma Thymic Carcinoma
Interventions
DRUG
No Results Yet
NCT03049475 | COMPLETED
99 Participants

Pathophysiology of Acute Pain in Patients With Sickle Cell Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2017-03-13
Completion: 2019-12-09
Conditions
Sickle Cell Disease
No Results Yet
NCT03017573 | RECRUITING | NA
1050 Participants

Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-01-06
Completion: 2029-08-06
Conditions
Ovarian Cancer Triple-Negative Breast Cancer Head and Neck Cancer Cervical Cancer Sarcoma
Interventions
PROCEDURE
No Results Yet
NCT03008291 | RECRUITING
80 Participants

His Bundle Pacing in Bradycardia and Heart Failure

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2016-10-31
Completion: 2026-12-31
Conditions
Bradycardia Heart Failure
Interventions
PROCEDURE
No Results Yet
NCT03003962 | ACTIVE_NOT_RECRUITING | PHASE3
669 Participants

Study of Durvalumab Alone or Chemotherapy for Patients With Advanced Non Small-Cell Lung Cancer (PEARL)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-01-02
Completion: 2022-10-27
Conditions
Non Small Cell Lung Carcinoma NSCLC
Interventions
DRUG
Results Available
NCT02991469 | RECRUITING | PHASE2
51 Participants

A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2018-08-09
Completion: 2026-04-01
Conditions
Juvenile Idiopathic Arthritis
Interventions
DRUG
No Results Yet
NCT02988128 | RECRUITING
4000 Participants

Neurovascular Product Surveillance Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2016-12-31
Completion: 2032-08-31
Conditions
Intracranial Aneurysm Stroke, Ischemic
Interventions
DEVICE
No Results Yet
NCT02975180 | COMPLETED | NA
11 Participants

FES in Young Children With Perinatal Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2018-01-01
Completion: 2020-12-10
Conditions
Cerebral Palsy
Interventions
DEVICE BEHAVIORAL
No Results Yet
NCT02973633 | RECRUITING | EARLY_PHASE1
160 Participants

Diffusion MRI in Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-06-30
Completion: 2027-12-31
Conditions
Myocardial Infarction Heart Failure Left Ventricular Hypertrophy
Interventions
DEVICE DRUG
No Results Yet
NCT02966756 | RECRUITING | PHASE2
110 Participants

A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-10-12
Completion: 2029-05-31
Conditions
Chronic Lymphocytic Leukemia (CLL) Small Lymphocytic Lymphoma (SLL)
Interventions
DRUG
No Results Yet
NCT02911714 | TERMINATED | PHASE1
20 Participants

Contrast-Enhanced Ultrasound for Kidney Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2018-02-21
Completion: 2022-06-30
Conditions
Kidney Transplantation
Interventions
DRUG
No Results Yet
NCT02830724 | RECRUITING | PHASE1/PHASE2
124 Participants

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-04-06
Completion: 2027-01-01
Conditions
Pancreatic Cancer Renal Cell Cancer Breast Cancer Melanoma Ovarian Cancer
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT02819037 | COMPLETED | NA
51 Participants

Small Intestinal Bacterial Overgrowth Obese

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2016-05-27
Completion: 2022-10-07
Conditions
Gastric Bypass Blind Loop Syndrome Bacterial Overgrowth Syndrome Chromatography, Gas
Interventions
PROCEDURE
No Results Yet
NCT02815891 | RECRUITING
15000 Participants

A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2016-07-31
Completion: 2036-07-31
Conditions
Nonalcoholic Fatty Liver Nonalcoholic Steatohepatitis
No Results Yet
NCT02782546 | ACTIVE_NOT_RECRUITING | PHASE2
60 Participants

Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2017-01-30
Completion: 2025-10-27
Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE DRUG
No Results Yet
NCT02771236 | RECRUITING
5000 Participants

Clinical and Molecular Studies in Families With Inherited Eye Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2016-10-04
Completion: 2032-01-01
Conditions
Inherited Eye Disease
No Results Yet
NCT02734069 | RECRUITING
132 Participants

Impact of Fat-free Mass in the Carboplatin Calculated Dose and Chemotherapeutic Toxicity in Patients With Advanced NSCLC

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2016-02-29
Completion: 2026-12-31
Conditions
Lung Cancer Sarcopenia Toxicity
Interventions
DRUG
No Results Yet
NCT02650401 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
69 Participants

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2016-05-03
Completion: 2026-06-30
Conditions
Solid Tumors CNS Tumors
Interventions
DRUG
No Results Yet
NCT02629120 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
45 Participants

High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2015-12-17
Completion: 2027-12-30
Conditions
Chronic Granulomatous Disease Transplant
Interventions
DRUG RADIATION BIOLOGICAL
No Results Yet
NCT02450851 | RECRUITING
20000 Participants

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2015-09-16
Completion: 2028-12-31
Conditions
Genetic Disease
No Results Yet
NCT02417714 | RECRUITING
215 Participants

Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2014-09-08
Completion: 2026-06-30
Conditions
Healthy Subjects
No Results Yet
NCT02405208 | COMPLETED
156 Participants

A Multi-center Outcomes Clinical Study of the PyroTITAN™ HRA Shoulder Implant in Humeral Head Resurfacing

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2010-08-31
Completion: 2023-09-30
Conditions
Arthritis
Interventions
DEVICE
Results Available
NCT02339012 | RECRUITING
900 Participants

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2015-03-15
Completion: 2099-12-31
Conditions
Healthy Volunteers Non-Healthy/Non-Frail Frail
No Results Yet
NCT02322177 | COMPLETED
2 Participants

Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry Protocol

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2014-12-19
Completion: 2018-08-20
Conditions
Inborn Errors of Metabolism Pregnancy Acidemias
No Results Yet
NCT02317328 | RECRUITING
1000 Participants

Adaptive Optics Retinal Imaging

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2015-02-20
Completion: 2028-03-31
Conditions
Eye Diseases Healthy Volunteers
No Results Yet
NCT02276924 | COMPLETED | NA
29 Participants

Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2013-10-31
Completion: 2016-10-31
Conditions
Hematuria Nephrolithiasis Cancer of Urinary Tract Ureteropelvic Junction Obstruction
Interventions
DEVICE
No Results Yet
NCT02215928 | RECRUITING
100 Participants

Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2014-07-28
Completion: 2026-12-31
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
GENETIC OTHER
No Results Yet
NCT02211768 | COMPLETED | PHASE1
10 Participants

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2014-12-08
Completion: 2017-09-05
Conditions
Neurofibromatosis MPNST
Interventions
PROCEDURE DRUG
No Results Yet
NCT02153957 | COMPLETED | PHASE2
36 Participants

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2014-08-21
Completion: 2023-02-14
Conditions
Brain Tumor
Interventions
BEHAVIORAL
No Results Yet
NCT02146170 | RECRUITING
2000 Participants

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2014-05-28
Completion: 2028-12-31
Conditions
Non-Small Cell Lung Cancer Small Cell Lung Cancer Extrapulmonary Small Cell Cancer Pulmonary Neuroendocrine Tumors Thymic Epithelial Tumors
No Results Yet
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