Clinical Trials
Showing trials with last updates posted in 2025.
396
Participants
A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-11-15
Completion:
2025-05-06
Conditions
Moderate to Severe Atopic Dermatitis
Interventions
DRUG
No Results Yet
1310
Participants
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-12-31
Completion:
2028-08-02
Conditions
Prostate Cancer Metastatic
Interventions
DRUG
No Results Yet
450
Participants
upREACH Perinatal Home Visitation Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-01-22
Completion:
2026-11-30
Conditions
Pregnancy
Postpartum
Interventions
BEHAVIORAL
No Results Yet
22
Participants
Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-07-23
Completion:
2026-01-30
Conditions
Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
20
Participants
Precision Dosing of Metformin in Youth With T2D
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-04-25
Completion:
2026-12-31
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
18
Participants
A Study of GC101 TIL in Advanced Melanoma (BZ)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-11-08
Completion:
2024-11-12
Conditions
Tumor Infiltrating Lymphocytes
Safety
Melanoma
Efficacy
Adverse Drug Event
Interventions
BIOLOGICAL
No Results Yet
616
Participants
Optimal Digital Weight Loss Treatment for Rural Individuals
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-01-03
Completion:
2027-02-28
Conditions
Overweight and Obesity
Interventions
BEHAVIORAL
No Results Yet
69
Participants
A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-11-29
Completion:
2025-11-05
Conditions
Eosinophilic Oesophagitis
Interventions
DRUG
No Results Yet
285
Participants
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-11-09
Completion:
2026-07-31
Conditions
Hepatocellular Carcinoma
Pancreatic Ductal Adenocarcinoma
Biliary Tract Cancers
Esophageal Squamous Cell Carcinoma
Triple Negative Breast Cancer
Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer
Head and Neck Squamous-Cell Carcinoma
Platinum Resistant High Grade Epithelial Ovarian Cancer
Interventions
DRUG
No Results Yet
10
Participants
Redesigning Pediatric Primary Care Obesity Treatment: Virtual House Calls
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-01-24
Completion:
2024-08-16
Conditions
Obesity, Pediatric
Interventions
BEHAVIORAL
5533
Participants
A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-11-20
Completion:
2026-03-30
Conditions
Obesity
Interventions
DRUG
No Results Yet
35
Participants
Magnetic Gastro-Ileal or Gastro-Jejunal Diversion Study ("MGI/MGJ Study")
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-11-06
Completion:
2026-03-31
Conditions
Obesity
Type 2 Diabetes
Interventions
DEVICE
No Results Yet
63
Participants
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2025-08-04
Completion:
2026-08-01
Conditions
Alcohol Use Disorder (AUD)
Alcohol-Related Disorders
Alcohol Use
Interventions
DRUG
No Results Yet
2734
Participants
A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-09-27
Completion:
2025-11-19
Conditions
Type 2 Diabetes Mellitus
Interventions
DRUG
No Results Yet
185
Participants
Pictou County PEP: A 6-Month, Home-Based, Personal Empowerment Program for Adults With a Chronic Medical Condition Living in Pictou County
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-11-24
Completion:
2025-05-14
Conditions
Chronic Condition
Interventions
BEHAVIORAL
No Results Yet
30
Participants
Study of the Size of the Operating Fields Depending on the Morphology of the Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2024-05-15
Completion:
2025-12-17
Conditions
Open Surgery on the Abdominal Aorta
Interventions
PROCEDURE
No Results Yet
234
Participants
iSCREEN-study: Online Nurse-assisted Eye-screening in Home Healthcare
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-03-23
Completion:
2025-11-03
Conditions
Eye Diseases
Interventions
DEVICE
No Results Yet
16
Participants
Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-10-01
Completion:
2026-09-01
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
256
Participants
Roadmap to Parenthood: Testing the Efficacy of a Decision Aid and Planning Tool for Family Building After Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-05-20
Completion:
2027-01-31
Conditions
Quality of Life
Parenthood Status
Interventions
OTHER
No Results Yet
48
Participants
Community Health Advocates for Motivating PAP Use in Our Neighborhoods.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-09-29
Completion:
2027-12-01
Conditions
Obstructive Sleep Apnea
Interventions
BEHAVIORAL
DEVICE
No Results Yet
120
Participants
Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-02-21
Completion:
2026-08-30
Conditions
Gastric Cancer
Immunonutrition
Gastrostomy
Interventions
DIETARY_SUPPLEMENT
No Results Yet
108
Participants
Wheelchair User Physical Activity Training Intervention to Enhance Cardiometabolic Health
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-08-10
Completion:
2027-10-01
Conditions
Physical Disability
Interventions
BEHAVIORAL
No Results Yet
594
Participants
A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-09-06
Completion:
2025-08-15
Conditions
Knee Osteoarthritis
Interventions
BIOLOGICAL
DRUG
No Results Yet
145
Participants
JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-02-20
Completion:
2030-06-03
Conditions
Severe Aplastic Anemia
Single Lineage Cytopenias, T-LGL
Hypoplastic MDS
Interventions
DRUG
No Results Yet
320
Participants
Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-01-18
Completion:
2026-02-02
Conditions
Acute Kidney Injury Due to Sepsis
Interventions
BIOLOGICAL
OTHER
No Results Yet
40
Participants
REVIVE (Response to the Ebola Virus Vaccine)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2025-12-01
Completion:
2026-05-31
Conditions
Ebola Virus Disease
Interventions
BIOLOGICAL
No Results Yet
400
Participants
Patterns and Glycaemic Endpoints for Diagnosing Gestational Diabetes
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2023-11-22
Completion:
2026-06-21
Conditions
Gestational Diabetes
Interventions
DEVICE
No Results Yet
53
Participants
A Phase 1/2 Study of AMG 193 in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-08-01
Completion:
2026-04-01
Conditions
MTAP-null Non-Small-Cell Lung Cancer
MTAP-null Solid Tumors
Interventions
DRUG
No Results Yet
125
Participants
Evaluating Treatments for Suicidal Veterans With PTSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-07-08
Completion:
2027-04-30
Conditions
Self-directed Violence
Post-traumatic Stress Disorder (PTSD)
Interventions
BEHAVIORAL
No Results Yet
20
Participants
Effect of Grapes in Inflammatory Bowel Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-09-16
Completion:
2025-08-01
Conditions
Crohn Disease
Interventions
DIETARY_SUPPLEMENT
No Results Yet
18
Participants
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-12-06
Completion:
2026-09-30
Conditions
Nicotine Dependence
Nicotine Vaping
Interventions
DRUG
No Results Yet
9
Participants
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-01-31
Completion:
2026-12-01
Conditions
Mesothelioma
Malignant Mesothelioma (MM)
Early-stage Mesothelioma
Subclinical Mesothelioma
BRCA1-Associated Protein-1 (BAP1) Mutations
Early-stage BAP1-associated Malignancies
Interventions
DRUG
No Results Yet
698
Participants
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-10-30
Completion:
2027-11-30
Conditions
Progressive Pulmonary Fibrosis
Interstitial Lung Disease
Interventions
DRUG
DEVICE
No Results Yet
533
Participants
Effect of Continuous Glucose Monitoring System Alerts on Diabetes Management in the Hospital
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2024-04-18
Completion:
2024-12-16
Conditions
Diabetes Mellitus
Interventions
DEVICE
No Results Yet
120
Participants
Advanced Renal Cell Cancer Combination ImmunoThErapy Clinical Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-09-25
Completion:
2026-01-10
Conditions
Advanced Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
425
Participants
Long Term Observational Study to Collect in a Real-world populatIon Data on the Treatment Pattern of secukinumAb in Adult Patients With Moderate to Severe Hidradenitis Suppurativa.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2023-08-10
Completion:
2027-03-31
Conditions
Hidradenitis Suppurativa
Interventions
OTHER
No Results Yet
40
Participants
Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS) - Stimulator of Interferon Genes (STING)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-05-31
Completion:
2024-02-29
Conditions
Crohn Disease
Ulcerative Colitis
Inflammatory Bowel Diseases
Interventions
BIOLOGICAL
PROCEDURE
No Results Yet
977
Participants
A Study of Hookah Café Customers in the Atlanta Area
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-06-01
Completion:
2024-11-21
Conditions
Waterpipe Tobacco Smoking
Interventions
BEHAVIORAL
306
Participants
Large De-NOVo Coronary artEry Disease Treated With Sirolimus Drug Eluting Balloon (LOVE DEB)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2023-07-12
Completion:
2025-12-11
Conditions
Coronary Artery Disease
No Results Yet
34
Participants
Combined Respiratory Training in Persons With ALS
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2023-08-22
Completion:
2026-09-30
Conditions
ALS
Respiratory Insufficiency
Dysphagia
Interventions
DEVICE
No Results Yet
Showing 40 trials per page