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Clinical Trials

Showing trials with last updates posted in 2025.

NCT03301506 | ACTIVE_NOT_RECRUITING | PHASE3
500 Participants

Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-12-12
Completion: 2028-11-30
Conditions
Primary Biliary Cirrhosis
Interventions
DRUG
No Results Yet
NCT03301220 | ACTIVE_NOT_RECRUITING | PHASE3
390 Participants

A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-11-07
Completion: 2024-05-01
Conditions
Smoldering Multiple Myeloma
Interventions
DRUG
Results Available
NCT03297073 | COMPLETED | NA
90 Participants

Paracetamol Metabolism Research in Postoperative Hepatic Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2016-11-20
Completion: 2018-04-30
Conditions
Paracetamol Causing Adverse Effects in Therapeutic Use Hepatic Disease
Interventions
DRUG PROCEDURE
No Results Yet
NCT03271333 | COMPLETED
56 Participants

Description of the Functional Evolution of Diffuse Infiltrating Pneumonia Associated With Systemic Scleroderma.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-04-10
Completion: 2024-12-31
Conditions
Systemic Sclerosis
Interventions
OTHER
No Results Yet
NCT03270982 | ACTIVE_NOT_RECRUITING
105 Participants

Comprehensive Segmental Revision System

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2016-04-30
Completion: 2035-12-31
Conditions
Degenerative Disease Oncology Revision Surgery Trauma Rheumatoid Arthritis
Interventions
DEVICE
No Results Yet
NCT03246516 | COMPLETED | NA
258 Participants

Determinants of Patient Delay in Doctor Consultation in Oeso-gastric Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-02-01
Completion: 2025-02-07
Conditions
Oesophageal Carcinoma Gastric Adenocarcinoma
Interventions
OTHER
No Results Yet
NCT03225547 | TERMINATED | PHASE2
24 Participants

Study of Pembrolizumab and Mifepristone in Patients With Advanced HER2-negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-02-12
Completion: 2025-09-30
Conditions
Triple Negative Breast Neoplasms Breast Cancer
Interventions
DRUG
No Results Yet
NCT03221036 | RECRUITING | PHASE3
402 Participants

Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-08-03
Completion: 2027-09-24
Conditions
Moderately to Severely Active Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT03195777 | COMPLETED | NA
51 Participants

Novel PET/CT and Treatment Strategies to Reduce PTS Following DVT

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-12-20
Completion: 2025-06-08
Conditions
Deep Venous Thrombosis Post-thrombotic Syndrome
Interventions
DEVICE
No Results Yet
NCT03191591 | COMPLETED | NA
1645 Participants

The First 1,000 Days Program: Maternal-Child Obesity Prevention in Early Life

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2016-08-09
Completion: 2021-03-18
Conditions
Overweight and Obesity Social Determinants of Health Physical Activity Sleep Feeding Behavior Diet Habit
Interventions
BEHAVIORAL
No Results Yet
NCT03161431 | ACTIVE_NOT_RECRUITING | PHASE1
77 Participants

SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-06-12
Completion: 2026-08-31
Conditions
Melanoma Stage III Melanoma Stage IV
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT03118193 | COMPLETED | NA
50 Participants

Biomarkers of Antidepressant Resistance

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-06-16
Completion: 2021-01-12
Conditions
Depression
Interventions
OTHER BIOLOGICAL DEVICE
No Results Yet
NCT03105336 | COMPLETED | PHASE2
159 Participants

A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-06-06
Completion: 2024-12-20
Conditions
Follicular Lymphoma Marginal Zone Lymphoma Indolent Non-Hodgkin Lymphoma
Interventions
BIOLOGICAL DRUG
Results Available
NCT03055182 | COMPLETED | NA
33 Participants

Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-01-11
Completion: 2024-12-10
Conditions
Low Back Pain Rehabilitation Program Muscular Weakness
Interventions
OTHER
No Results Yet
NCT03042169 | TERMINATED | PHASE3
6 Participants

Surgical Resection Plus Chemotherapy Versus Chemotherapy Alone in Oligometastatic Stage IV Gastric Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-08-25
Completion: 2024-08-28
Conditions
Gastric Adenocarcinoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT03038022 | COMPLETED | PHASE2
116 Participants

Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-02-23
Completion: 2018-01-15
Conditions
Heterozygous Familial Hypercholesterolemia
Interventions
DRUG
Results Available
NCT03034122 | COMPLETED
77 Participants

Is Caffeine an Environmental Modifier in Huntington's Disease?

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2017-10-11
Completion: 2024-04-12
Conditions
Huntington Disease
No Results Yet
NCT03024229 | COMPLETED | NA
40 Participants

Metabolomics in Assessing the Quality of Kidney Transplants Retained on a LifePort® Perfusion Machine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-03-15
Completion: 2019-09-15
Conditions
Renal Transplantation
Interventions
DEVICE
No Results Yet
NCT02998164 | ACTIVE_NOT_RECRUITING | NA
154 Participants

Improving Outcomes Using Technology for Children Who Are DHH

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2016-10-31
Completion: 2025-12-31
Conditions
Hearing Loss Language Development Social Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT02972008 | RECRUITING
542 Participants

Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2017-03-09
Completion: 2026-02-28
Conditions
Cognitive Decline Stroke
No Results Yet
NCT02948972 | RECRUITING | NA
120 Participants

Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2016-11-17
Completion: 2026-05-31
Conditions
Endometriosis Infertility
Interventions
PROCEDURE
No Results Yet
NCT02922569 | COMPLETED | NA
23 Participants

Home-Based, Online, Mindfulness and Cognitive Training for Soldiers and Veterans With TBI

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-03-31
Completion: 2020-08-30
Conditions
Mild Traumatic Brain Injury
Interventions
OTHER
No Results Yet
NCT02912260 | COMPLETED | PHASE2
125 Participants

Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2016-10-18
Completion: 2017-10-25
Conditions
Non-alcoholic Steatohepatitis
Interventions
DRUG
Results Available
NCT02899416 | COMPLETED
72 Participants

Better Life by Nutrition During Adulthood

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2017-02-23
Completion: 2022-03-25
Conditions
Cardiovascular Risk Factor
No Results Yet
NCT02864992 | ACTIVE_NOT_RECRUITING | PHASE2
337 Participants

Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2016-09-13
Completion: 2022-05-16
Conditions
Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification Lung Adenocarcinoma Stage IIIB/IV
Interventions
DRUG
Results Available
NCT02841553 | RECRUITING
5000 Participants

Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2011-07-31
Completion: 2027-04-30
Conditions
Wolfram Syndrome Diabetes Mellitus Optic Nerve Atrophy Deafness Diabetes Insipidus Ataxia
No Results Yet
NCT02684292 | COMPLETED | PHASE3
304 Participants

Study of Pembrolizumab (MK-3475) vs. Brentuximab Vedotin in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (MK-3475-204/KEYNOTE-204)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2016-05-23
Completion: 2025-12-10
Conditions
Hodgkin Lymphoma
Interventions
BIOLOGICAL
No Results Yet
NCT02657863 | COMPLETED
61 Participants

Cancer DNA Detection in Blood and Urine

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2014-11-30
Completion: 2022-04-30
Conditions
Prostate Cancer
Interventions
PROCEDURE
No Results Yet
NCT02635022 | RECRUITING
200 Participants

Fragility Fracture Liaison Service and Anti-osteoporosis Medication Monitoring Service Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2015-09-30
Completion: 2026-12-31
Conditions
Osteoporosis Fracture
No Results Yet
NCT02301767 | ACTIVE_NOT_RECRUITING
2187 Participants

MRI Background Parenchymal Enhancement as a Risk Factor for Breast Cancer: The IMAGINg and Epidemiology (IMAGINE) Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2014-11-30
Completion: 2026-11-30
Conditions
Breast Cancer
No Results Yet
NCT02141074 | COMPLETED | PHASE3
54 Participants

Safety and Efficacy of Nonacog Beta Pegol (N9-GP) in Previously Untreated Patients With Haemophilia B

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2014-07-02
Completion: 2022-10-27
Conditions
Congenital Bleeding Disorder Haemophilia B
Interventions
DRUG
Results Available
NCT02137850 | COMPLETED | PHASE3
124 Participants

Safety and Efficacy of Turoctocog Alfa Pegol (N8-GP) in Previously Untreated Patients With Haemophilia A

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2014-06-26
Completion: 2023-06-07
Conditions
Congenital Bleeding Disorder Haemophilia A
Interventions
DRUG
Results Available
NCT02119689 | ACTIVE_NOT_RECRUITING
78 Participants

Vascular Reparative Mechanism in Diabetes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2011-10-30
Completion: 2026-12-31
Conditions
Diabetic Retinopathy
Interventions
OTHER
No Results Yet
NCT02116764 | COMPLETED
137 Participants

Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2014-06-11
Completion: 2022-06-02
Conditions
Chronic Granulomatous Disease
No Results Yet
NCT02108041 | COMPLETED
196 Participants

Personalized Medicine Decision-Making in a Virtual Clinical Setting

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Completion: 2020-10-08
Conditions
Deep Vein Thrombosis Blood Clots
No Results Yet
NCT01942239 | COMPLETED | NA
48 Participants

Real-time Continuous Glucose Monitoring in Very Low Birth Weight Neonates

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2008-12-31
Completion: 2009-11-30
Conditions
Hypoglycemia
Interventions
DEVICE
No Results Yet
NCT01860339 | RECRUITING
400 Participants

Child to Adult Neurodevelopment in Gene Expanded Huntington's Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2005-07-31
Completion: 2026-08-31
Conditions
Huntington's Disease
No Results Yet
NCT01737606 | COMPLETED | NA
53 Participants

Ultrasonic Explorations of Cerebral Tissue Motions - Influence of Aging

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2012-09-30
Completion: 2013-06-30
Conditions
Aging Cerebral Pulsatility
Interventions
DEVICE
No Results Yet
NCT01617408 | RECRUITING
665 Participants

Brain Stimulation and Vision Testing

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2013-03-04
Conditions
fMRI Dorsal Pathway Ventral Pathway
No Results Yet
NCT01467427 | COMPLETED | PHASE3
25 Participants

Safety, Efficacy and Pharmacokinetics of NNC-0156-0000-0009 in Previously Treated Children With Haemophilia B.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2012-05-16
Completion: 2023-11-17
Conditions
Congenital Bleeding Disorder Haemophilia B
Interventions
DRUG
Results Available
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