Clinical Trials

Showing trials with last updates posted in 2025.

NCT03725930 | COMPLETED | PHASE3
90 Participants

Premedication by Clonidine Intranasal in Pediatric Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-03-26
Completion: 2021-11-24
Conditions
Child Preschool
Interventions
DRUG OTHER
No Results Yet
NCT03711643 | COMPLETED | NA
88 Participants

Hypnosis Mask: a New Approach to Management of Pain in Medical Imaging

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-05-07
Completion: 2021-10-26
Conditions
Prostatic Diseases
Interventions
PROCEDURE DEVICE
No Results Yet
NCT03691064 | ACTIVE_NOT_RECRUITING
1014 Participants

Post-Authorization Long-Term Safety Study of LUTATHERA

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-11-28
Completion: 2027-09-30
Conditions
Neuroendocrine Tumors
Interventions
DRUG
No Results Yet
NCT03681678 | COMPLETED
100 Participants

Laser Therapy for Treatment of Urogenital Symptoms in Women

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-10-08
Completion: 2022-12-15
Conditions
Genitourinary System; Disorder, Female Burning Vagina Dyspareunia Irritation; Vagina Menopause Related Conditions Urinary Incontinence Urinary Bladder, Overactive Urinary Tract Infections Stress Urinary Incontinence
Interventions
DEVICE
NCT03673124 | ACTIVE_NOT_RECRUITING | PHASE2
51 Participants

Ribociclib and Letrozole Treatment in Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-05-20
Completion: 2024-12-23
Conditions
Low Grade Serous Carcinoma
Interventions
DRUG
NCT03610698 | COMPLETED | NA
386 Participants

Life Enhancing Activities for Family Caregivers (LEAF 2.0)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-07-13
Completion: 2024-09-04
Conditions
Caregivers
Interventions
BEHAVIORAL OTHER
NCT03608553 | COMPLETED | NA
20 Participants

A Study to Evaluate Temporary Blood Brain Barrier Disruption in Patients With Parkinson's Disease Dementia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-11-26
Completion: 2021-10-31
Conditions
Parkinsons Disease With Dementia
Interventions
DEVICE
No Results Yet
NCT03600233 | ACTIVE_NOT_RECRUITING | PHASE2
34 Participants

Study of CVM-1118 for Patients With Advanced Neuroendocrine Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-12-15
Completion: 2024-09-30
Conditions
Neuroendocrine Tumors Pancreatic Neuroendocrine Tumor Gastro-enteropancreatic Neuroendocrine Tumor Lung Neuroendocrine Neoplasm Neuroendocrine Carcinoma
Interventions
DRUG
No Results Yet
NCT03598790 | COMPLETED | PHASE3
1353 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-09-05
Completion: 2023-11-14
Conditions
Chronic Plaque Psoriasis Moderate to Severe Chronic Plaque Psoriasis
Interventions
DRUG
NCT03568318 | ACTIVE_NOT_RECRUITING | PHASE3
1533 Participants

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-08-09
Completion: 2021-02-16
Conditions
Atopic Dermatitis
Interventions
DRUG
NCT03565770 | COMPLETED | NA
106 Participants

Assessment of Individual Follow-up by Coaching Program for Type 1 Diabetes Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-09-29
Completion: 2021-06-25
Conditions
Diabetes type1
Interventions
OTHER
No Results Yet
NCT03559465 | COMPLETED | NA
71 Participants

Profibrosing Role of B Lymphocytes in Patients With Systemic Sclerosis.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-10-29
Completion: 2023-02-14
Conditions
Scleroderma, Systemic
Interventions
PROCEDURE OTHER
No Results Yet
NCT03536884 | COMPLETED | PHASE3
743 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-06-13
Completion: 2019-09-12
Conditions
Chronic Plaque Psoriasis Moderate to Severe Chronic Plaque Psoriasis
Interventions
DRUG OTHER
NCT03528226 | RECRUITING | NA
34 Participants

Exercise Training and Endothelial Function in Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-11-12
Completion: 2026-01-31
Conditions
Type1diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT03519945 | ACTIVE_NOT_RECRUITING | PHASE3
1063 Participants

A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-07-18
Completion: 2026-07-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT03519802 | COMPLETED
140 Participants

Evaluation of Cognitive Function in a Suicidal Crisis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2016-09-20
Completion: 2024-03-25
Conditions
Suicide
No Results Yet
NCT03517072 | RECRUITING
1000 Participants

Determinants of the Long-Term Success of Bariatric Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-07-31
Completion: 2026-01-31
Conditions
Morbid Obesity Bariatric Surgery Candidate
No Results Yet
NCT03517059 | COMPLETED
29 Participants

Study of Dysarthria, and the Appearance of Non-dopaminergic Signs in Idiopathic PARKinson's Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2017-05-11
Completion: 2018-11-12
Conditions
Parkinson Disease
No Results Yet
NCT03492424 | RECRUITING
200 Participants

Ablative Therapy in the Management of Prostate Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-01-02
Completion: 2032-03-02
Conditions
Prostate Cancer
Interventions
DEVICE
No Results Yet
NCT03491683 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
52 Participants

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-05-31
Completion: 2026-12-31
Conditions
Glioblastoma
Interventions
BIOLOGICAL RADIATION DRUG
No Results Yet
NCT03483792 | COMPLETED
58 Participants

Heritability of Polycystic Ovary Syndrome: Role of Antimullerian Hormone, Steroids and Leptin

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-04-20
Completion: 2022-06-02
Conditions
Polycystic Ovary Syndrome
Interventions
BIOLOGICAL GENETIC
No Results Yet
NCT03473743 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
125 Participants

A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-04-05
Completion: 2022-09-30
Conditions
Urothelial Carcinoma
Interventions
DRUG
NCT03454425 | COMPLETED | NA
36 Participants

A Study to Evaluate the Safety and Efficacy of ExAblate Subthalomotomy for the Treatment of Parkinson's Disease Motor Features

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-02-27
Completion: 2020-06-15
Conditions
Parkinson Disease
Interventions
DEVICE
No Results Yet
NCT03451851 | ACTIVE_NOT_RECRUITING | PHASE3
120 Participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-07-11
Completion: 2023-07-19
Conditions
Psoriasis
Interventions
DRUG
NCT03438643 | TERMINATED
8 Participants

Dynamic of Immunocompetent Populations in Patients Treated With Extracorporeal Photopheresis in Chronic Graft Versus Host Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-05-07
Completion: 2019-12-02
Conditions
Graft Versus Host Disease Extracorporeal Photopheresis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03431350 | ACTIVE_NOT_RECRUITING | PHASE2
136 Participants

A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-03-02
Completion: 2021-08-31
Conditions
Prostatic Neoplasms, Castration-Resistant
Interventions
DRUG
NCT03412747 | COMPLETED | PHASE3
478 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-01-26
Completion: 2019-02-07
Conditions
Chronic Plaque Psoriasis Moderate to Severe Plaque Psoriasis
Interventions
DRUG OTHER
NCT03410992 | COMPLETED | PHASE3
435 Participants

A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-02-05
Completion: 2018-12-28
Conditions
Chronic Plaque Psoriasis Moderate to Severe Chronic Plaque Psoriasis Psoriatic Arthritis
Interventions
DRUG OTHER
NCT03381274 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
43 Participants

Oleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-05-08
Completion: 2021-05-24
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL DRUG
NCT03370133 | COMPLETED | PHASE3
567 Participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Placebo and an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-12-06
Completion: 2019-01-08
Conditions
Chronic Plaque Psoriasis Moderate to Severe Chronic Plaque Psoriasis Psoriatic Arthritis
Interventions
DRUG OTHER
NCT03369522 | COMPLETED
40 Participants

Development of an Epileptic Seizure Detection Algorithm by Continuous Analysis of the Electrocardiogram

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2017-12-13
Completion: 2019-12-12
Conditions
Seizures Epilepsy Electrocardiography
No Results Yet
NCT03331250 | ACTIVE_NOT_RECRUITING | PHASE2
13 Participants

Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-01-18
Completion: 2023-07-21
Conditions
Angiosarcoma Epithelioid Hemangioendothelioma
Interventions
DRUG
NCT03301506 | ACTIVE_NOT_RECRUITING | PHASE3
500 Participants

Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-12-12
Completion: 2028-11-30
Conditions
Primary Biliary Cirrhosis
Interventions
DRUG
No Results Yet
NCT03301220 | ACTIVE_NOT_RECRUITING | PHASE3
390 Participants

A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-11-07
Completion: 2024-05-01
Conditions
Smoldering Multiple Myeloma
Interventions
DRUG
NCT03297073 | COMPLETED | NA
90 Participants

Paracetamol Metabolism Research in Postoperative Hepatic Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2016-11-20
Completion: 2018-04-30
Conditions
Paracetamol Causing Adverse Effects in Therapeutic Use Hepatic Disease
Interventions
DRUG PROCEDURE
No Results Yet
NCT03271333 | COMPLETED
56 Participants

Description of the Functional Evolution of Diffuse Infiltrating Pneumonia Associated With Systemic Scleroderma.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-04-10
Completion: 2024-12-31
Conditions
Systemic Sclerosis
Interventions
OTHER
No Results Yet
NCT03270982 | ACTIVE_NOT_RECRUITING
105 Participants

Comprehensive Segmental Revision System

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2016-04-30
Completion: 2035-12-31
Conditions
Degenerative Disease Oncology Revision Surgery Trauma Rheumatoid Arthritis
Interventions
DEVICE
No Results Yet
NCT03246516 | COMPLETED | NA
258 Participants

Determinants of Patient Delay in Doctor Consultation in Oeso-gastric Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-02-01
Completion: 2025-02-07
Conditions
Oesophageal Carcinoma Gastric Adenocarcinoma
Interventions
OTHER
No Results Yet
NCT03225547 | TERMINATED | PHASE2
24 Participants

Study of Pembrolizumab and Mifepristone in Patients With Advanced HER2-negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2018-02-12
Completion: 2025-09-30
Conditions
Triple Negative Breast Neoplasms Breast Cancer
Interventions
DRUG
No Results Yet
NCT03221036 | RECRUITING | PHASE3
402 Participants

Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-08-03
Completion: 2027-09-24
Conditions
Moderately to Severely Active Ulcerative Colitis
Interventions
DRUG
No Results Yet
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