Clinical Trials
Showing trials with last updates posted in 2025.
56
Participants
A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-04-30
Completion:
2027-10-31
Conditions
Hearing Loss, Bilateral Sensorineural
Interventions
DEVICE
No Results Yet
66
Participants
Chinese Herbal Therapy (Qiqi Shengmai Formula) for Moyamoya Vasculopathy: The CHIMES Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-30
Completion:
2026-11-30
Conditions
Moyamoya Disease
Moyamoya Syndrome
Interventions
DRUG
No Results Yet
90
Participants
Intensive Rehabilitation Program for Upper Limb in Children and Adolescents With Cerebral Palsy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-11-21
Completion:
2030-12-31
Conditions
Cerebral Palsy (CP)
Interventions
OTHER
No Results Yet
90
Participants
Inhaled RB042 in Healthy Adult Volunteers and Healthy Adult Smokers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-31
Completion:
2027-02-28
Conditions
Healthy
Healthy Smoker
Interventions
DRUG
No Results Yet
80
Participants
Bupivacaine With or Without Dexmedetomidine for Postoperative Pain Relief in Abdominal Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-01
Completion:
2025-12-31
Conditions
Pain, Postoperative
Interventions
DRUG
No Results Yet
27
Participants
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-18
Completion:
2026-12-18
Conditions
Amyloidosis
Basal Cell Carcinoma
Biliary Tract Carcinoma
Bladder Carcinoma
Breast Carcinoma
Cervical Carcinoma
Colorectal Carcinoma
Endometrial Carcinoma
Fallopian Tube Carcinoma
Gastroesophageal Junction Carcinoma
Glioblastoma
Head and Neck Carcinoma
Hematopoietic and Lymphatic System Neoplasm
Hepatocellular Carcinoma
Hodgkin Lymphoma
Lung Carcinoma
Malignant Solid Neoplasm
Mantle Cell Lymphoma
Melanoma
Merkel Cell Carcinoma
Multiple Myeloma
Myelodysplastic Syndrome
Ovarian Carcinoma
Pancreatic Carcinoma
Primary Peritoneal Carcinoma
Prostate Carcinoma
Renal Cell Carcinoma
Squamous Cell Carcinoma
Urothelial Carcinoma
Interventions
DRUG
OTHER
No Results Yet
1100
Participants
Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-04-30
Completion:
2029-06-30
Conditions
Idiopathic Pulmonary Fibrosis (IPF)
Interventions
DRUG
No Results Yet
40
Participants
Infant Swing and Sleep-Wake Cycles
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-20
Completion:
2026-03-31
Conditions
Sleep Quality
Interventions
OTHER
No Results Yet
20
Participants
A Phase IB Trial of Subcutaneous Blinatumomab in Combination With Revumenib for Patients With KMT2A-rearranged Acute Lymphoblastic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-05-18
Completion:
2029-08-31
Conditions
Blinatumomab
Revumenib
Lymphoblastic Leukemia
KMT2A-rearranged
Interventions
DRUG
No Results Yet
13
Participants
Community-based Functional Fitness for Adults Aging With Mobility Disability
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-10-17
Completion:
2024-11-20
Conditions
Mobility Disability
Older Adults
Interventions
BEHAVIORAL
No Results Yet
478
Participants
Early Versus Delayed Trial Without Catheter in Men With Acute Urinary Retention.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-08-21
Completion:
2027-09-04
Conditions
Acute Urinary Retention
Benign Prostate Obstruction
Benign Prostate Hyperplasia
Benign Prostate Hypertrophy(BPH)
Interventions
PROCEDURE
No Results Yet
40
Participants
Methionine Intake Microbiota
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-20
Completion:
2026-03-31
Conditions
Healthy
Interventions
BEHAVIORAL
No Results Yet
219
Participants
Study of TYK-01054 Capsules in Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-01-01
Completion:
2028-01-31
Conditions
Solid Tumor Malignancies
Malignant Mesothelioma (MM)
Interventions
DRUG
No Results Yet
64
Participants
Sensory and Functional Impairments in Cervical Disc Herniation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2025-10-24
Completion:
2025-12-03
Conditions
Cervical Disc Herniation
Interventions
OTHER
No Results Yet
60
Participants
Clinical Validity of the DANU Sports System for Gait and Balance Assessment in Parkinson's Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2025-08-08
Completion:
2027-09-30
Conditions
Parkinson Disease (PD)
Healthy (Controls)
No Results Yet
91
Participants
Effect of Exercise on Ultrasound SWV in CTS Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-04-07
Completion:
2025-07-14
Conditions
Carpal Tunnel Syndrome
Peripheral Neuropathies
Interventions
OTHER
No Results Yet
136
Participants
Preoperative Use of Romiplostim in Thrombocytopenic Patients Undergoing Cardiac Surgery.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-01-01
Completion:
2028-04-01
Conditions
Chirurgical Intervention
Thrombocytopaenia
Interventions
DRUG
No Results Yet
648
Participants
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-01
Completion:
2026-03-31
Conditions
Postpartum Hemorrhage
Delivery Complication
Cesarean Section Complications
Perinatal Problems
Interventions
DRUG
No Results Yet
35
Participants
Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-02
Completion:
2026-12-31
Conditions
Sjogren Syndrome With Keratoconjunctivitis
Interventions
DRUG
No Results Yet
54
Participants
Effect of Autogenic Training on Hemodialysis Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-15
Completion:
2027-03-15
Conditions
Hemodialysis Patient
Restless Leg Syndrome (RLS)
Fatigue
Sleep Disturbance
Interventions
BEHAVIORAL
OTHER
No Results Yet
786
Participants
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-31
Completion:
2028-12-31
Conditions
Severe Asthma
Interventions
DRUG
No Results Yet
40
Participants
[99mTc]Tc-DB8 Accumulation in Primary Tumor in Breast Cancer With Positive and Negative Estrogen Receptor Expression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-10-01
Completion:
2026-12-31
Conditions
Primary Breast Cancer
Interventions
DRUG
No Results Yet
100
Participants
Periodontal Health and Sodium Bicarbonate Toothpaste
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-12-04
Completion:
2026-10-20
Conditions
Periodontal Diseases
Interventions
PROCEDURE
No Results Yet
60
Participants
The Effect of Graded Forced Expiration on Intraocular Pressure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-15
Completion:
2026-02-10
Conditions
Intraocular Pressure
Interventions
OTHER
No Results Yet
738
Participants
A Phase III Study to Evaluate the Efficacy and Safety of MDR-001 in Adult Participants With Overweight or Obesity (MOBILE）
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-02-28
Completion:
2027-06-30
Conditions
Overweight or Obesity
Interventions
DRUG
No Results Yet
1898
Participants
Dronedarone Rhythm Intervention for Early Atrial Fibrillation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-01-01
Completion:
2028-06-30
Conditions
Atrial Fibrillation (AF)
Interventions
DRUG
No Results Yet
24
Participants
Rehabilitation Based on Hybrid Neuroprosthesis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-02-12
Completion:
2024-05-24
Conditions
Post Stroke
Interventions
DEVICE
No Results Yet
256
Participants
Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2026-03-02
Completion:
2027-03-02
Conditions
Trauma Centers
Trauma Patients
Trauma (Including Fractures)
Trauma Injury
Rehabilitation After Neurological or Orthopaedic Injuries
Rehabilitation
Return to Work
HRQOL (Health Related Quality Of Life)
EQ5D5L-VAS
Interventions
OTHER
No Results Yet
30
Participants
TITAN-HCC: Neoadjuvant and Adjuvant QL1706 With TACE in Resectable Hepatocellular Carcinoma Beyond Milan Criteria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-20
Completion:
2026-10-31
Conditions
Hepatocellular Carcinoma (HCC)
Interventions
COMBINATION_PRODUCT
No Results Yet
58
Participants
Effects of Muscle Energy Techniques With and Without Manual Axial Distraction in Post-Mastectomy Patients With Axillary Web Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-13
Completion:
2026-05-25
Conditions
Axillary Web Syndrome
Post-mastectomy
Interventions
OTHER
No Results Yet
70
Participants
Effects of Neck Stabilizers Retraining on Chronic Neck Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-11-28
Completion:
2026-05-28
Conditions
Neck Pain Musculoskeletal
Chronic Neck Pain
Interventions
OTHER
No Results Yet
92
Participants
PREPARE: Perioperative REhabilitation Around Vaginal Prolapse RepAir Surgery for Recovery Enhancement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-11-24
Completion:
2027-06-25
Conditions
Postoperative Physical Functioning
Interventions
OTHER
No Results Yet
104
Participants
A Study to Evaluate Efficacy and Safety of IBI112 in Adolescent Participants With Moderate to Severe Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-03
Completion:
2026-09-30
Conditions
Psoriasis
Interventions
DRUG
No Results Yet
40
Participants
Effect of a Mouthwash Containing Chlorhexidine and Chlorine Dioxide on Halitosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-09-05
Completion:
2023-12-05
Conditions
Halitosis
Interventions
OTHER
No Results Yet
24
Participants
Safety and Feasibility of IRE for Early-stage Breast Cancer: a Prospective, Open-Label, Single-Arm, Exploratory Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-11
Completion:
2026-03-15
Conditions
Breast Cancer
Interventions
DEVICE
No Results Yet
400
Participants
Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-09-01
Completion:
2027-09-01
Conditions
Pancreas Head Cancer
Pancreas Adenocarcinoma
IPMN, Pancreatic
Cholangio Carcinoma
Ampulla of Vater Adenocarcinoma
PDAC - Pancreatic Ductal Adenocarcinoma
Duodenal Carcinoma
Mucinous Cystic Neoplasm
Neuro Endocrine Tumours
Pancreatitis
Interventions
COMBINATION_PRODUCT
No Results Yet
25
Participants
Clinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-11-22
Completion:
2026-12-02
Conditions
Dental Caries
Class II Dental Caries
Interventions
PROCEDURE
No Results Yet
38
Participants
Gut Microbiome in Gynecological Cancer Patients With Pelvic Toxicity: Controls Versus Ozone Treatment. (MicrOzoGineTox)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2026-01-15
Completion:
2028-01-15
Conditions
Pelvic Toxicity
Radiation Toxicity
Chemotherapy Toxicity
Gynecological Tumors
Radiation Proctitis
Radiation Cystitis
Vaginal Mucositis
Vulvar Mucositis
Quality of Life
Dysbiosis
No Results Yet
94
Participants
Escitalopram Plasma Concentrations in Premenopausal and Postmenopausal Women
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2026-01-31
Completion:
2028-01-31
Conditions
Therapeutic Drug Monitoring (TDM)
Menopause
Depression - Major Depressive Disorder
General Anxiety Disorder
No Results Yet
41
Participants
A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-31
Completion:
2027-01-31
Conditions
Neoplasms
Healthy
Interventions
DRUG
No Results Yet
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