Clinical Validity of the DANU Sports System for Gait and Balance Assessment in Parkinson's Disease

NCT ID: NCT07281794

Last Updated: 2025-12-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-08-08

Study Completion Date

2027-09-30

Brief Summary

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This observational study aims to explore the use of the DANU Smart Socks for gait and balance assessment in people with Parkinson's (PwP). The study will compare walking and balance outcomes produced by DANU from people with Parkinson's (PwP) and a group of healthy individuals of similar age. The project aims to investigate if the gait and balance data collected are linked to measures of Parkinson's symptoms such as disease progression and cognitive abilities. Gait and balance outcomes will be obtained through one observational laboratory visit.

Detailed Description

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Methods:

Institutional ethics have been obtained (Project ID: 8543). Utilising an observational design, participants will be asked to attend one visit to Northumbria University, Newcastle Upon Tyne.

Visit 1: Participants will complete a series of clinical and cognitive measures including the Movement Disorders Society's-Unified Parkinson's Disease Rating Scale, Montreal Cognitive Assessment, Freezing of Gait Questionnaire and Falls Efficacy Scale to act as descriptive measures. Following this, the investigators will conduct a concurrent data collection throughout a battery of motor tasks. The DANU system will be used alongside APDM Mobility Lab throughout the full duration of data collection. Mobility assessments include a 2-Minute Walk Test, 3 walkway trials, a Timed Up and Go and a series of 2-Minute Balance tasks.

Conditions

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Parkinson Disease (PD) Healthy (Controls)

Keywords

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DANU Clinical Validation Wearable Electronic Devices

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Parkinson's Disease (PD)

Participants with a clinical diagnosis of Parkinson's Disease meeting the described eligibility criteria will be recruited to take part within this study. The aim is to recruit 60 people with Parkinson's.

No interventions assigned to this group

Healthy Control (HC)

Aged-matched (over 50 years old) healthy controls who meet the described eligibility criteria will be recruited to participate in this study. The aim is to recruit 60 participants.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* PD stages I-III (Hoehn and Yahr Rating Scale)
* Able to attend Northumbria University, Newcastle Upon Tyne for study visits.
* Able to walk and stand unassisted for a minimum of 2-minutes.
* Aged 50 years old or over


* Ability to attend Northumbria University, Newcastle Upon Tyne for study visits.
* Aged 50 years old or over.
* Able to walk and stand unassisted for a minimum of 2-minutes.

Exclusion Criteria

* History of neurological disorders other than PD (e.g., Huntington's disease, stroke, traumatic brain injury, multiple sclerosis, Alzheimer's disease etc.)
* Unable to walk or stand unaided.
* Montreal Cognitive Assessment (MoCA) score \< 21
* Significant issues unrelated to PD that may affect gait (e.g., musculoskeletal issues, back pain, recent surgery etc.)


* History of neurological disorders (e.g. Huntington's disease, stroke, traumatic brain injury, multiple sclerosis, Alzheimer's disease etc.)
* Significant issues that may affect walking (e.g., musculoskeletal issues, back pain, recent surgery etc.)
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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DANU Sports Ltd

UNKNOWN

Sponsor Role collaborator

Northumbria University

OTHER

Sponsor Role lead

Responsible Party

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GabriellaGatti

Postgraduate Research Student

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Rodrigo Vitorio, PhD

Role: PRINCIPAL_INVESTIGATOR

Northumbria University

Locations

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Northumbria University

Newcastle upon Tyne, , United Kingdom

Site Status

Countries

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United Kingdom

Related Links

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https://www.danumedical.com/

DANU Medical Website: Study Collaborator and Smart Sock System.

Other Identifiers

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8543b

Identifier Type: -

Identifier Source: org_study_id