Clinical Trials Updated in 2025

NCT07052396 | RECRUITING

350 Participants

Study to Evaluate Long-term Effectiveness and Safety, Patient Characteristics and Subjective Patient-reported Outcomes of Dupilumab in Patients With Chronic Obstructive Pulmonary Disease (COPD) Under Real-world Conditions

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2025-07-01

Completion: 2029-07-01

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

DRUG

No Results Yet

NCT07048509 | RECRUITING | NA

45 Participants

Difference in Acute Responses of Vascular Function to Moderate-intensity and High-intensity Interval Training in Healthy and Prehypertensive Individuals

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-24

Completion: 2026-05-31

Conditions

Prehypertension (Elevated Blood Pressure) or Hypertension Healthy

Interventions

OTHER

No Results Yet

NCT07048197 | RECRUITING | PHASE1/PHASE2

27 Participants

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-20

Completion: 2028-11-01

Conditions

Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)

Interventions

BIOLOGICAL

No Results Yet

NCT07046923 | RECRUITING | PHASE1

240 Participants

A Study of LY4175408 in Participants With Advanced Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-07-28

Completion: 2030-07-31

Conditions

Carcinoma, Non-Small-Cell Lung Small Cell Lung Carcinoma Endometrial Neoplasms Neoplasm Metastasis Triple Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT07046143 | ENROLLING_BY_INVITATION | NA

62 Participants

Study on the Efficacy of Non-invasive Spinal Cord Electrical Stimulation in Neuropathic Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-25

Completion: 2026-06-15

Conditions

Neuropathic Pain

Interventions

DEVICE

No Results Yet

NCT07044648 | NOT_YET_RECRUITING | NA

70 Participants

Middle Meningeal Artery Embolization for Chronic Migraine

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2026-01-31

Completion: 2027-08-31

Conditions

Migraine

Interventions

PROCEDURE

No Results Yet

NCT07037771 | RECRUITING | PHASE3

60 Participants

A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-17

Completion: 2027-08-20

Conditions

Homozygous Familial Hypercholesterolemia

Interventions

DRUG

No Results Yet

NCT07027215 | COMPLETED | NA

40 Participants

Augmented Sensory in Cancer-Related Neuropathic Patients"

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-01-20

Completion: 2024-03-25

Conditions

Physical Therapy

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07024745 | ACTIVE_NOT_RECRUITING | NA

66 Participants

PrEP US NoW: PrEP Utilization Through Increasing Social Capital Among YBMSM Networks With Women

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-05-09

Completion: 2025-11-30

Conditions

PrEP Uptake

Interventions

BEHAVIORAL

No Results Yet

NCT07023614 | RECRUITING | PHASE2

165 Participants

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-10-06

Completion: 2026-12-31

Conditions

Non-obstructive Hypertrophic Cardiomyopathy

Interventions

DRUG

No Results Yet

NCT07022184 | RECRUITING | NA

216 Participants

Lifestyle Intervention for Symptoms of Depression wIth App Support in General Practice

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-17

Completion: 2026-11-30

Conditions

Depressive/Anxiety Symptoms Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT07015281 | ACTIVE_NOT_RECRUITING | NA

100 Participants

Dry Needling With Percutaneous Electrical Nerve Stimulation and Exercises for Non-specific Chronic Neck Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-30

Completion: 2025-12-30

Conditions

Neck Pain

Interventions

OTHER

No Results Yet

NCT07008469 | ENROLLING_BY_INVITATION | PHASE3

230 Participants

Global Open-Label Extension Study of Del-desiran for the Treatment of DM1

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-07-25

Completion: 2030-08-31

Conditions

Myotonic Dystrophy Type 1 DM1 Myotonic Dystrophy Myotonia Myotonic Dystrophy 1 Myotonic Disorders Steinert Myotonic Dystrophy Steinert Disease

Interventions

DRUG

No Results Yet

NCT07007819 | ENROLLING_BY_INVITATION | NA

50 Participants

Community-Engaged Sleep Intervention for School-Aged Children With Autism Spectrum Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-08-27

Completion: 2026-08-01

Conditions

Sleep Disturbance Autism Spectrum Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07006857 | COMPLETED | NA

30 Participants

Effects of Exercise With Different Music Frequencies

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-07-01

Completion: 2025-10-30

Conditions

Physical Inactivity

Interventions

OTHER

No Results Yet

NCT06992492 | COMPLETED | NA

90 Participants

Vojta Reflex Versus Lung Squeezing Technique in Respiratory Distress Preterm Neonate

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-27

Completion: 2025-10-08

Conditions

Respiratory Distress Syndrome

Interventions

PROCEDURE

No Results Yet

NCT06992258 | RECRUITING | PHASE2

120 Participants

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-10-27

Completion: 2027-12-31

Conditions

Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06990724 | RECRUITING | NA

850 Participants

Effectiveness Testing of a Videogame Intervention (No Baby No) to Decrease Contraception Non-use Among Adolescents.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-11

Completion: 2027-11-30

Conditions

Contraceptive Usage Contraception Behavior

Interventions

OTHER

No Results Yet

NCT06984809 | RECRUITING | NA

180 Participants

Evaluation of the Invest in Play Program - a New Parent Intervention for Children With Problem Behavior

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-09-25

Completion: 2028-12-31

Conditions

Problem Behavior Attention Deficit and Disruptive Behavior Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06983171 | ACTIVE_NOT_RECRUITING

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-04

Completion: 2027-06-30

Conditions

Parkinson Disease

No Results Yet

NCT06963021 | RECRUITING | PHASE3

200 Participants

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-30

Completion: 2027-07-31

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT06962137 | RECRUITING | PHASE2

100 Participants

Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-12-11

Completion: 2029-12-31

Conditions

Gastric Cancer Adenocarcinoma Metastatic Gastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG OTHER

No Results Yet

NCT06958796 | RECRUITING | PHASE4

80 Participants

Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-11-27

Completion: 2027-12-30

Conditions

Cytomegalovirus Organ Transplant Kidney Transplant; Complications Liver Transplant Complications Simultaneous Liver-Kidney Transplantation; Complications

Interventions

DRUG

No Results Yet

NCT06954090 | ENROLLING_BY_INVITATION | PHASE4

50 Participants

Urinary Proteomics to Guide Early Intervention to Prevent Complications in Type 2 Diabetes - a Feasibility Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-11-20

Completion: 2026-11-30

Conditions

Type 2 DM Type 2 DM /Diabetic Nephropathy Albuminuria

Interventions

DRUG

No Results Yet

NCT06952907 | RECRUITING | NA

340 Participants

Femoral Versus Radial Invasive Arterial Pressure Monitoring in Cardiac Surgery Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-15

Completion: 2027-07-01

Conditions

Vasoplegia Syndrome Vasoplegia Cardiac Surgical Procedures Arterial Pressure Hypotension During Surgery Hypotension Postprocedural Norepinephrine

Interventions

OTHER

No Results Yet

NCT06952738 | RECRUITING

200 Participants

Investigating Periprosthetic Fracture Cultures in Arthroplasty

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2025-10-01

Completion: 2027-04-30

Conditions

Periprosthetic Fracture Around Prosthetic Joint Implant

Interventions

OTHER

No Results Yet

NCT06949553 | RECRUITING

250 Participants

An Observational Study to Learn More About Vasomotor Symptoms Burden and Treatment Patterns in Menopausal Women Before and After Participating in OASIS Studies

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2025-04-30

Completion: 2028-05-15

Conditions

Vasomotor Symptoms (VMS) Associated With Menopause

Interventions

OTHER

No Results Yet

NCT06947993 | RECRUITING | PHASE2

224 Participants

Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-16

Completion: 2028-11-27

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06935656 | COMPLETED | NA

192 Participants

Effectiveness of Three Executive Function Interventions on Direct and Far Transfer in Chilean School Children

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-05

Completion: 2025-11-26

Conditions

Executive Functions

Interventions

OTHER

No Results Yet

NCT06934538 | RECRUITING | PHASE1/PHASE2

90 Participants

First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-17

Completion: 2028-06-30

Conditions

Unresectable Metastatic Colorectal Cancer Unresectable Locally Advanced Colorectal Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06925321 | RECRUITING | PHASE3

219 Participants

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-08-26

Completion: 2028-02-29

Conditions

Invasive Mold Infections

Interventions

DRUG

No Results Yet

NCT06923527 | RECRUITING | PHASE2

50 Participants

Circulating Tumor DNA

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-09-30

Completion: 2027-09-30

Conditions

ER+ Breast Cancer

Interventions

DRUG

No Results Yet

NCT06920680 | RECRUITING

1834 Participants

ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2024-10-01

Completion: 2026-10-31

Conditions

Colorectal Cancer Colonoscopy Polypectomy

No Results Yet