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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06764342 | COMPLETED | NA
40 Participants

Adjunctive Effect of Photodynamic Therapy on Halitosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-01-08
Completion: 2025-02-22
Conditions
Periodontitis Halitosis
Interventions
RADIATION PROCEDURE
No Results Yet
NCT06764082 | RECRUITING | NA
120 Participants

Nutritional Intervention for Biliary Atresia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-01
Completion: 2028-06-30
Conditions
Nutrition Disorder, Infant Biliary Atresia
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06757803 | COMPLETED | NA
60 Participants

The Analgesic Effect of Retro-laminar Block Versus Paravertebral Block in Patients With Multiple Fracture Ribs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-12-12
Completion: 2025-12-02
Conditions
Rib Fracture
Interventions
PROCEDURE
No Results Yet
NCT06753916 | RECRUITING | PHASE2
96 Participants

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-01
Completion: 2028-01-01
Conditions
Corneal Transplant Failure
Interventions
PROCEDURE
No Results Yet
NCT06743191 | COMPLETED | NA
67 Participants

Delivering a Digital Health Intervention to Improve Food Access and Dietary Quality Among Adults With Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-27
Completion: 2025-12-18
Conditions
Hypertension
Interventions
BEHAVIORAL
No Results Yet
NCT06742996 | RECRUITING | PHASE3
300 Participants

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-05
Completion: 2028-08-31
Conditions
Mantle Cell Lymphoma B Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT06736990 | RECRUITING | PHASE2
150 Participants

A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-20
Completion: 2027-08-31
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT06735248 | RECRUITING | PHASE2
180 Participants

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-16
Completion: 2029-01-08
Conditions
Multiple Sclerosis
Interventions
BIOLOGICAL
No Results Yet
NCT06728579 | RECRUITING | PHASE2
200 Participants

Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-12-06
Completion: 2028-12-31
Conditions
Breast Cancer Survivor
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06714110 | ENROLLING_BY_INVITATION
200 Participants

A Review of Precice Intramedullary Limb Lengthening (IMLL) System for Limb Lengthening Procedures in Children.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-13
Completion: 2026-07-30
Conditions
Limb Length Discrepancy
Interventions
DEVICE
No Results Yet
NCT06713837 | RECRUITING | PHASE3
339 Participants

IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-27
Completion: 2028-01-31
Conditions
Acute Myeloid Leukemia Relapse/Recurrence
Interventions
DRUG
No Results Yet
NCT06705400 | RECRUITING | NA
3500 Participants

The Bloom Study - a Safe and Healthy Start in Life

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-11-01
Completion: 2029-03-31
Conditions
Overweight, Childhood Obesity in Children
Interventions
BEHAVIORAL
No Results Yet
NCT06703892 | RECRUITING | PHASE1
18 Participants

A Study to Evaluate the Safety and Clinical Activity of GF- CART01 (CD20/19 CAR T Cell) in Subjects With Relapsed or Refractory B-Cell Hematological Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-09
Completion: 2027-03-31
Conditions
Diffuse Large B Cell Lymphoma Relapsed Diffuse Large B Cell Lymphoma Refractory Follicular Lymphoma ( FL) Primary Mediastinal Large B-Cell Lymphoma-Refractory Primary Mediastinal Large B-Cell Lymphoma-Recurrent High-grade B-cell Lymphoma (HGBCL)
Interventions
BIOLOGICAL
No Results Yet
NCT06702371 | ACTIVE_NOT_RECRUITING | NA
105 Participants

Digital Body Mindset Intervention for Young Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-11-29
Completion: 2026-02-28
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06693752 | RECRUITING | PHASE2
20 Participants

CEUS Evaluation of Hydrocephalus in Neonates and Infants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-01-15
Completion: 2026-08-01
Conditions
Hydrocephalus in Infants Hydrocephalus Acquired
Interventions
DRUG
No Results Yet
NCT06686667 | COMPLETED | NA
31 Participants

The Feasibility of Overnight Time Restricted Eating and Impact on Glucose Levels in Shift Workers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-24
Completion: 2025-07-10
Conditions
Shift Work Eating Behaviors
Interventions
BEHAVIORAL
No Results Yet
NCT06686485 | RECRUITING
433 Participants

cOncomitant Left Atrial aPpendage Closure and Pulsed Field ablaTION-Asia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-18
Completion: 2026-10-31
Conditions
Concomitant Procedures Atrial Fibrillation PFA LAAC
Interventions
DEVICE
No Results Yet
NCT06685640 | RECRUITING | NA
10 Participants

Comparison of Clinical Success of Stainless Steel Crowns and Zirconia Crowns in Primary Molars

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-07-30
Completion: 2026-08-30
Conditions
Dental Caries Pulpotomy
Interventions
OTHER
No Results Yet
NCT06681272 | ACTIVE_NOT_RECRUITING
84 Participants

Prediction of Chronic Pain in Cardiac Surgery: Evaluation by Algocartography Predict-ALGOCARTE

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-11-27
Completion: 2025-11-27
Conditions
Sternotomy Closure,Open Heart Surgery Cardiac Surgery Chronic Pain Post-Procedural
Interventions
OTHER
No Results Yet
NCT06679140 | RECRUITING | PHASE3
2330 Participants

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-12-08
Completion: 2026-12-06
Conditions
COVID-19 SARS-CoV-2 Infection
Interventions
DRUG
No Results Yet
NCT06667453 | RECRUITING | PHASE2
24 Participants

A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-12-10
Completion: 2026-08-31
Conditions
Myotonic Dystrophy 1
Interventions
DRUG OTHER
No Results Yet
NCT06661473 | ACTIVE_NOT_RECRUITING | NA
105 Participants

Interventional Study Exploring the Occurrence of Surgical Site Infections.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-03
Completion: 2025-12-31
Conditions
Total Knee Arthroplasty Total Hip Arthroplasty Revision Total Knee Arthroplasty Revision
Interventions
DEVICE
No Results Yet
NCT06659146 | RECRUITING | NA
60 Participants

Thermotherapy in Addition to SOC Palliative Radiotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-14
Completion: 2028-03-01
Conditions
Head and Neck Squamous Cell Carcinoma Cutaneous Squamous Cell Carcinoma Breast Cancer Recurrent
Interventions
DEVICE
No Results Yet
NCT06654193 | RECRUITING | PHASE1/PHASE2
70 Participants

Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-01-31
Completion: 2028-01-01
Conditions
Acute Kidney Injury
Interventions
DRUG
No Results Yet
NCT06648434 | RECRUITING | PHASE1
51 Participants

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-15
Completion: 2027-06-30
Conditions
Metastatic Pancreatic Ductal Adenocarcinoma Pancreatic Cancer Cancer of the Pancreas
Interventions
DRUG
No Results Yet
NCT06647979 | RECRUITING | PHASE1
10 Participants

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-01
Completion: 2028-12-31
Conditions
Sickle Cell Disease Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0) Beta-Thalassemia Transfusion Dependent Beta-Thalassaemia
Interventions
BIOLOGICAL DEVICE
No Results Yet
NCT06647953 | RECRUITING | PHASE3
110 Participants

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-21
Completion: 2029-03-31
Conditions
Pleuropulmonary Blastoma
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER
No Results Yet
NCT06644664 | ACTIVE_NOT_RECRUITING | NA
300 Participants

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-24
Completion: 2026-08-31
Conditions
Tobacco-Related Carcinoma
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06627764 | RECRUITING | NA
400 Participants

SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-30
Completion: 2028-07-31
Conditions
Substance Abuse Intimate Partner Violence (IPV) HIV Infections Depression Anxiety
Interventions
BEHAVIORAL
No Results Yet
NCT06627647 | RECRUITING | PHASE3
878 Participants

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-11-27
Completion: 2029-05-10
Conditions
Non-squamous Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06627439 | COMPLETED | NA
160 Participants

A Web-Based Healthy Living Training for Promotores

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-13
Completion: 2025-07-31
Conditions
Obesity Prevention
Interventions
BEHAVIORAL
No Results Yet
NCT06625775 | RECRUITING | PHASE1
392 Participants

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-29
Completion: 2028-11-30
Conditions
Advanced Breast Cancer Solid Tumor, Adult Metastatic Breast Cancer HER2 Mutation-Related Tumors HER2-positive Metastatic Breast Cancer KRAS Mutant Metastatic Colorectal Cancer Metastatic Lung Cancer Metastatic Colorectal Cancer Advanced Lung Cancer HR-positive, HER2-negative Advanced Breast Cancer HER2-positive Advanced Breast Cancer
Interventions
DRUG
No Results Yet
NCT06620276 | RECRUITING | NA
30 Participants

ACT_for Alcohol Use Disorder and Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-01
Completion: 2026-12-01
Conditions
Depression - Major Depressive Disorder Alcohol Use Disorder
Interventions
BEHAVIORAL DRUG
No Results Yet
NCT06613620 | COMPLETED | NA
46 Participants

Additional Effects of Surface Electromyographic Biofeedback on Post Facilitation Stretching and Strengthening in Lower Crossed Syndrome;A Randomized Control Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-07-18
Completion: 2025-06-02
Conditions
Lower Cross Syndrome
Interventions
OTHER
No Results Yet
NCT06609343 | RECRUITING | PHASE1/PHASE2
16 Participants

Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-02-02
Completion: 2026-11-30
Conditions
End Stage Renal Disease Fatigue
Interventions
DRUG
No Results Yet
NCT06588855 | RECRUITING | PHASE3
350 Participants

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-12-11
Completion: 2027-06-30
Conditions
Moderately to Severely Active Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT06588491 | ACTIVE_NOT_RECRUITING | PHASE2
25 Participants

KYSA-8: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Treatment Refractory Stiff Person Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-25
Completion: 2026-04-30
Conditions
Stiff-Person Syndrome SPS
Interventions
BIOLOGICAL
No Results Yet
NCT06586515 | RECRUITING | PHASE1
630 Participants

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-12
Completion: 2029-03-31
Conditions
Pancreatic Ductal Adenocarcinoma Non-small Cell Lung Cancer Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT06584916 | COMPLETED | PHASE3
376 Participants

A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-13
Completion: 2025-11-21
Conditions
Obesity Overweight
Interventions
DRUG
No Results Yet
NCT06581198 | RECRUITING | PHASE2
179 Participants

A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-04
Completion: 2028-02-14
Conditions
Lupus Erythematosus, Systemic Lupus Nephritis
Interventions
BIOLOGICAL
No Results Yet
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