Clinical Trials
Showing trials with last updates posted in 2025.
100
Participants
ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-05-06
Completion:
2026-01-31
Conditions
Vasodilatory Hypotension During or After Cardiac Surgery
Interventions
DRUG
No Results Yet
200
Participants
A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-09
Completion:
2027-07-06
Conditions
Diffuse Cutaneous Systemic Sclerosis
Interventions
DRUG
No Results Yet
20
Participants
Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2025-05-27
Completion:
2026-06-30
Conditions
Breast Neoplasms
No Results Yet
420
Participants
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-07-01
Completion:
2027-05-31
Conditions
Metastatic Solid Tumor
Recurrent Solid Tumor
Advanced Solid Tumor
Urinary Bladder Neoplasm
Triple Negative Breast Cancer
Non-small Cell Lung Cancer
Esophageal Cancer
Pancreatic Cancer
Ovarian Cancer
Cervical Cancer
Head and Neck Squamous Cell Carcinoma
Prostate Cancer
Renal Pelvis Cancer
Bladder Cancer
Interventions
DRUG
No Results Yet
50
Participants
Adapting and Piloting Acceptance and Commitment Therapy (ACT) for Severe Premenstrual Mood Symptoms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-12-01
Completion:
2026-06-30
Conditions
Premenstrual Dysphoric Disorder
Premenstrual Exacerbation of Mood Disorder
Interventions
BEHAVIORAL
No Results Yet
4000
Participants
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-28
Completion:
2032-07-31
Conditions
Acute Myeloid Leukemia, in Relapse
Acute Myeloid Leukemia Refractory
Interventions
OTHER
No Results Yet
278
Participants
A Study to Learn More About How Well Sevabertinib (BAY 2927088) Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-08-28
Completion:
2027-10-28
Conditions
Advanced Non-small Cell Lung Cancer
HER2 Mutation
Interventions
DRUG
No Results Yet
1130
Participants
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-05-24
Completion:
2027-05-15
Conditions
Colorectal Cancer
CRC
Pancreatic Ductal Adenocarcinoma
PDAC
Gastrointestinal Cancer
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
192
Participants
Patient's Perspective on the Evolution of Hidradenitis Suppurativa Burden After Secukinumab Initiation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-17
Completion:
2027-06-30
Conditions
Hidradenitis Suppurativa
Interventions
OTHER
No Results Yet
400
Participants
Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-02-26
Completion:
2035-02-27
Conditions
Systemic Lupus
Autoimmune Diseases
Autoinflammatory Disease
Genetic Disease
Interventions
GENETIC
OTHER
No Results Yet
154
Participants
Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-09-12
Completion:
2026-12-14
Conditions
Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
Interventions
DRUG
No Results Yet
7
Participants
NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-05-31
Completion:
2025-08-12
Conditions
Advanced Cholangiocarcinoma
Metastatic Cholangiocarcinoma
Refractory Cholangiocarcinoma
Stage III Hilar Cholangiocarcinoma AJCC v8
Stage III Intrahepatic Cholangiocarcinoma AJCC v8
Stage IV Hilar Cholangiocarcinoma AJCC v8
Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Interventions
PROCEDURE
BIOLOGICAL
No Results Yet
324
Participants
Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-05-22
Completion:
2025-09-22
Conditions
Behavior Problem
Interventions
DRUG
No Results Yet
124
Participants
Ringer Acetate Based Modified Del Nido Cardioplegia Solution Versus HTK Solution Cardioplegia Solution in Cardiac Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-01
Completion:
2025-11-12
Conditions
Cardiac Ischemia
Interventions
BIOLOGICAL
No Results Yet
55
Participants
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-05-29
Completion:
2030-01-31
Conditions
Pediatric
Symptomatic Obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG
No Results Yet
20
Participants
In-patient Comparison of Immediately Loaded and Non-loaded Submerged and Transgingival Healed Implants Within 4 Months
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-09-28
Completion:
2025-10-29
Conditions
Jaw, Edentulous
Interventions
PROCEDURE
No Results Yet
17
Participants
Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes: Open Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-04-08
Completion:
2025-02-15
Conditions
Body Weight
Weight Bias
Weight Stigma
Weight
Interventions
BEHAVIORAL
No Results Yet
121
Participants
Understanding Aided Speech Perception in Noise
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-11-16
Completion:
2028-03-01
Conditions
Hearing Impairment, Sensorineural
Spatial Perception
Aging
Hearing Aids
Interventions
DEVICE
No Results Yet
1600
Participants
Effectiveness of Cognitive Training in Older and Younger Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-01
Completion:
2028-01-31
Conditions
Cognitive Change
Interventions
BEHAVIORAL
No Results Yet
240
Participants
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-22
Completion:
2033-11-04
Conditions
Basal Ganglia Germinoma
Central Nervous System Germinoma
Diabetes Insipidus
Pineal Region Germinoma
Suprasellar Germinoma
Thalamic Germinoma
Interventions
RADIATION
PROCEDURE
DRUG
OTHER
No Results Yet
500
Participants
Evolve China PMCF Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-04-24
Completion:
2027-11-30
Conditions
Intracranial Aneurysm
Interventions
DEVICE
No Results Yet
10
Participants
Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-04-30
Completion:
2025-11-17
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
DRUG
No Results Yet
60
Participants
68Ga-FAPI-46 PET/CT for Predicting Histological Response in Triple-negative Breast Cancer (FAP-IT)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-14
Completion:
2032-11-30
Conditions
Triple Negative Breast Cancer
Interventions
PROCEDURE
No Results Yet
120
Participants
The Effect of the Anticholinergic Burden Following Elective Coronary Artery Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-01-01
Completion:
2025-10-01
Conditions
Postoperative Recovery
Length of Hospital Stay
Postoperative Complications
Interventions
DRUG
No Results Yet
572
Participants
AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-03-04
Completion:
2026-05-14
Conditions
Gastric Cancer
Gastroesophageal Junction Cancer
Interventions
DRUG
No Results Yet
326
Participants
A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-04-08
Completion:
2025-11-24
Conditions
Uncontrolled Hypertension
Resistant Hypertension
Interventions
DRUG
No Results Yet
6
Participants
A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-14
Completion:
2027-03-08
Conditions
Diffuse Hemispheric Glioma, H3 G34-Mutant
Interventions
PROCEDURE
BIOLOGICAL
DRUG
No Results Yet
130
Participants
Comparison of Individualized Sodium Management Versus Standard Treatment in Hemodialysis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-12-16
Completion:
2026-12-31
Conditions
End Stage Renal Disease
Interventions
DEVICE
No Results Yet
41
Participants
Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-01-13
Completion:
2025-08-31
Conditions
Autism Spectrum Disorder
Language Development
Literacy
Interventions
BEHAVIORAL
No Results Yet
288
Participants
Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-28
Completion:
2028-08-22
Conditions
Polymyalgia Rheumatica
Interventions
BIOLOGICAL
No Results Yet
520
Participants
A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-04-10
Completion:
2028-07-25
Conditions
Recurrent or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
160
Participants
Food Insecurity Reduction & Strategy Team
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-10-07
Completion:
2026-03-31
Conditions
Diabetes Mellitus, Type 2
Food Insecurity
Diabetes Mellitus, Type 1
Interventions
OTHER
No Results Yet
40
Participants
Testing the Engaged Approach to Lung Cancer Screening
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-03-11
Completion:
2024-10-30
Conditions
Lung Cancer
Interventions
BEHAVIORAL
No Results Yet
768
Participants
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-06-03
Completion:
2029-01-08
Conditions
Metastatic Breast Cancer
Metastatic Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Esophageal Adenocarcinoma
Colorectal Cancer
Interventions
DRUG
No Results Yet
80
Participants
US Imaging for the Assessment of LUTS
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-11-28
Completion:
2027-01-31
Conditions
Lower Urinary Tract Symptoms
BPH
Interventions
DEVICE
No Results Yet
200
Participants
An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-03-05
Completion:
2027-03-31
Conditions
Retinopathy of Prematurity
Preterm Infants
Interventions
DRUG
No Results Yet
36
Participants
A Study in Healthy Japanese Men to Test How Well Different Doses of BI 3006337 Are Tolerated
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-04-19
Completion:
2024-10-31
Conditions
Healthy
Interventions
DRUG
60
Participants
A Digital Treatment for Adolescents With Eating Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-03-11
Completion:
2027-01-01
Conditions
Eating Disorders
Interventions
BEHAVIORAL
No Results Yet
1000
Participants
PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2024-07-25
Completion:
2034-05-31
Conditions
Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency
ATP-Binding Cassette Subfamily C Member 6 Deficiency
Interventions
OTHER
No Results Yet
60
Participants
Needs Navigation for Caregivers of AYAs
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-02-16
Completion:
2026-07-31
Conditions
Cancer in Adolescence
Interventions
BEHAVIORAL
No Results Yet
Showing 40 trials per page