Evolve China PMCF Study

NCT ID: NCT06368622

Last Updated: 2025-12-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-04-24

Study Completion Date

2031-08-31

Brief Summary

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A prospective, multi-center, single-arm, open-label, observational, post-market clinical follow-up. The expected duration of the study is 8 years (including up to 5-years' follow-up). Each subject will be followed up per standard of care (SoC) at each study site.

Detailed Description

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Conditions

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Intracranial Aneurysm

Keywords

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intracranial aneurysms flow diverter system Surpass Evolve Flow Diverter System Surpass Evolve

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Surpass Evolve Flow Diverter System

Endovascular treatment with Surpass Evolve Flow Diverter System was performed in patients diagnosed with intracranial aneurysms

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subject age is ≥ 18 and ≤80 years
* Subject is eligible for Surpass Evolve FDS IFU, and/or physician intends to treat the subject with Surpass Evolve FDS per his/her judgement
* Subject, or subject's legally authorised representative (LAR) has provided signed informed consent using the Ethics Committee (EC)-approved consent form
* Subject is willing to comply with scheduled visits and examinations per institutional SOC

Exclusion Criteria

* Subject has any non-target intracranial aneurysm treated within 30 days prior to study enrollment
* Subject has a planned treatment of a non-target aneurysm in the same vascular territory during participation in the study within 12 months post procedure
* Subject has undergone previous treatment where it would interfere with the delivery and/ or placement and/or proper apposition of Surpass Evolve FDS
* Subject has acute target aneurysm rupture and/or subarachnoid hemorrhage occurred within 30 days prior to enrollment
* Subject has any condition demonstrated as Warning or Precautions in IFU
* Antiplatelet and/or anticoagulation therapy (e.g. aspirin and clopidogrel) is contraindicated for the subject
* Subject has not received dual anti-platelet agents prior to the procedure
* Subject with an active bacterial infection
* Subject in whom the angiography demonstrates the anatomy is not appropriate for endovascular treatment, due to conditions such as:

* Severe intracranial vessel tortuosity or stenosis; and/or
* Intracranial vasospasm not responsive to medical therapy
* Female subjects who are pregnant/ nursing, or who are unwilling or unable to take adequate method of contraception prior to the 12-month study follow-up.\*

\*If the subject becomes pregnant during her participation, the physician will have to evaluate the risk associated to her continuing participation to the rest of the study.
* Enrollment in another trial involving an investigational product and/or drug interfere with study procedure/ results
* The investigator determined that the health of the patient may be compromised by the patient's enrollment
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stryker (Beijing) Healthcare Products Co., Ltd

INDUSTRY

Sponsor Role collaborator

Stryker Neurovascular

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Xuanwu Hospital Capital Medical University

Beijing, , China

Site Status RECRUITING

Beijing Tiantan Hospital, Capital Medical University

Beijing, , China

Site Status RECRUITING

Peking University Third Hospital

Beijing, , China

Site Status ACTIVE_NOT_RECRUITING

Beijing Chao-Yang Hospital, Capital Medical University

Beijing, , China

Site Status RECRUITING

Bethune First Hospital of Jilin University

Changchun, , China

Site Status RECRUITING

The First Affiliated Hospital of Fujian Medical University

Fuzhou, , China

Site Status RECRUITING

Guangdong Second Provincial General Hospital

Guangzhou, , China

Site Status RECRUITING

First Affiliated Hospital of Kunming Medical University

Kunming, , China

Site Status RECRUITING

Nanyang Central Hospital

Nanyang, , China

Site Status RECRUITING

Ningbo Medical Center Lihuili Hospital

Ningbo, , China

Site Status RECRUITING

The Affiliated Hospital of Qingdao University

Qingdao, , China

Site Status RECRUITING

The Affiliated Hospital of Qingdao University

Qingdao, , China

Site Status RECRUITING

The Affiliated Hospital of Qingdao University

Qingdao, , China

Site Status RECRUITING

Shanghai Fourth People's Hospital Affiliated To Tongji University

Shanghai, , China

Site Status RECRUITING

South China Hospital of Shenzhen University

Shenzhen, , China

Site Status RECRUITING

The Eighth Affiliated Hospital, Sun Yat-sen University (Shenzhen Futian)

Shenzhen, , China

Site Status RECRUITING

The Third Hospital of Hebei Medical University

Shijiazhuang, , China

Site Status RECRUITING

Tangshan Workers' Hospital

Tangshan, , China

Site Status RECRUITING

Tianjin Huanhu Hospital

Tianjin, , China

Site Status RECRUITING

Weifang People's Hospital

Weifang, , China

Site Status RECRUITING

The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, , China

Site Status RECRUITING

Xiangyang No.1 People's Hospital

Xiangyang, , China

Site Status RECRUITING

Zhuhai People's Hospital

Zhuhai, , China

Site Status RECRUITING

The Fifth Affiliated Hospital, Sun Yat-sen University

Zhuhai, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Mingyao Zheng

Role: CONTACT

Phone: +86 13761826075

Email: [email protected]

Facility Contacts

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Hongqi Zhang

Role: primary

Ming Lv

Role: primary

Yang Wang

Role: primary

Honglei Wang

Role: primary

Yuanxiang Lin

Role: primary

Xuying He

Role: primary

Peng Bai

Role: primary

Changming Wen

Role: primary

Maosong Chen

Role: primary

Rui Xu

Role: primary

Zhiyong Yan

Role: primary

Yong Zhang

Role: primary

Yibin Fang

Role: primary

Shiwei Du

Role: primary

Bin Luo

Role: primary

Pinyuan Zhang

Role: primary

Xiang Xu

Role: primary

Hongguang Wang

Role: primary

Zengwu Wang

Role: primary

Jianfeng Han

Role: primary

Peiyang Zhou

Role: primary

Guangsen Cheng

Role: primary

Other Identifiers

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CDM10001814

Identifier Type: -

Identifier Source: org_study_id