Clinical Trials
Showing trials with last updates posted in 2025.
25
Participants
Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-09-08
Completion:
2025-01-30
Conditions
Fallopian Tube Endometrioid Adenocarcinoma
Fallopian Tube High Grade Serous Adenocarcinoma
Ovarian Endometrioid Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Primary Peritoneal Endometrioid Adenocarcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Stage III Fallopian Tube Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage III Primary Peritoneal Cancer AJCC v8
Stage IV Fallopian Tube Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8
Stage IV Primary Peritoneal Cancer AJCC v8
Unresectable Fallopian Tube Endometrioid Adenocarcinoma
Unresectable Fallopian Tube High Grade Serous Adenocarcinoma
Unresectable Ovarian Endometrioid Adenocarcinoma
Unresectable Ovarian High Grade Serous Adenocarcinoma
Unresectable Primary Peritoneal Endometrioid Adenocarcinoma
Unresectable Primary Peritoneal High Grade Serous Adenocarcinoma
Interventions
PROCEDURE
DRUG
164
Participants
Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-11
Completion:
2027-04-30
Conditions
Advanced Cancer
Interventions
DRUG
No Results Yet
283
Participants
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused Etentamig (ABBV-383) in Combination With Anti-Cancer Regimens for the Treatment of Adult Participants With Relapsed/Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-10-20
Completion:
2033-09-30
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
528
Participants
Optimal Duration of Dual Antiplatelet Therapy After Stent-assisted Coiling
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-06-23
Completion:
2025-12-02
Conditions
Aneurysm Cerebral
Endovascular Procedures
Interventions
DRUG
No Results Yet
151
Participants
A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-01
Completion:
2025-05-30
Conditions
Amyloidosis
Interventions
DRUG
No Results Yet
70
Participants
A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-15
Completion:
2026-06-30
Conditions
Metastatic Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
703
Participants
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-22
Completion:
2025-05-23
Conditions
Crohn's Disease
Interventions
BIOLOGICAL
DRUG
No Results Yet
304
Participants
The Lifestyle Education About Prediabetes (Leap) Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-20
Completion:
2025-11-14
Conditions
PreDiabetes
Interventions
BEHAVIORAL
No Results Yet
60
Participants
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-04
Completion:
2029-03-28
Conditions
Early-Onset Alzheimer Disease
Interventions
DRUG
No Results Yet
1350
Participants
Drug-Coated Balloon in Patients With High Bleeding Risk
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-29
Completion:
2027-11-30
Conditions
Coronary Artery Disease
Interventions
PROCEDURE
No Results Yet
Post-trial Access for Nipocalimab in Participants With Warm Autoimmune Hemolytic Anemia (wAIHA)
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-19
Conditions
Warm Autoimmune Hemolytic Anemia
Interventions
DRUG
No Results Yet
45
Participants
PANHPVAX, Study of a New HPV Vaccine in Healthy Volunteers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-11-07
Completion:
2027-12-31
Conditions
HPV
Interventions
BIOLOGICAL
No Results Yet
74
Participants
VIBRANT: VIB4920 for Active Lupus Nephritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-05-16
Completion:
2026-08-31
Conditions
Lupus Nephritis
Interventions
DRUG
No Results Yet
25
Participants
NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-22
Completion:
2026-07-01
Conditions
Chronic Granulomatous Disease
Infection
Interventions
BIOLOGICAL
No Results Yet
68
Participants
A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-03
Completion:
2025-11-07
Conditions
Candidiasis, Invasive
Candidemia
Interventions
DRUG
No Results Yet
417
Participants
A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-09-27
Completion:
2026-12-31
Conditions
Venous Thromboembolism
Deep Venous Thrombosis
Pulmonary Embolism
Interventions
BIOLOGICAL
DRUG
No Results Yet
65
Participants
Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-12-01
Completion:
2027-06-30
Conditions
Healthy
Vasodilation
Insulin Resistance
Autonomic Dysfunction
Obesity
Interventions
OTHER
DRUG
No Results Yet
116
Participants
Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-01-03
Completion:
2026-05-31
Conditions
Alzheimer Disease, Late Onset
Mild Cognitive Impairment
Sleep
Cognitive Change
Amyloid
Interventions
BEHAVIORAL
No Results Yet
24
Participants
Off-the-shelf NK Cells + SCT for Myeloid Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-04-08
Completion:
2025-05-15
Conditions
Myeloid Malignancies
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Chronic Myeloid Leukemia
Interventions
DRUG
6106
Participants
A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-11-02
Completion:
2024-11-20
Conditions
Chronic Heart Failure With Reduced Ejection Fraction
Interventions
DRUG
100
Participants
Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-10
Completion:
2030-01-01
Conditions
Hyperinsulinism
Interventions
DRUG
No Results Yet
60
Participants
Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-09-07
Completion:
2027-11-30
Conditions
Allogeneic Hematopoietic Cell Transplantation (HCT)
Advanced Hematologic Malignancies
Acute Leukemia
Chronic Myelogenous Leukemia
Myelodysplastic Syndromes
Myeloproliferative Disorders
Interventions
DRUG
DEVICE
No Results Yet
48
Participants
A Study of Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile Psoriatic Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-30
Completion:
2026-12-10
Conditions
Arthritis, Juvenile
Interventions
DRUG
No Results Yet
587
Participants
A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-14
Completion:
2028-12-08
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
350
Participants
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-12-07
Completion:
2026-04-06
Conditions
Stereotypical Prolonged Seizures
Interventions
DRUG
OTHER
No Results Yet
300
Participants
A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-03
Completion:
2028-11-30
Conditions
Stereotypical Prolonged Seizures
Interventions
DRUG
No Results Yet
60
Participants
Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-01
Completion:
2023-03-01
Conditions
Analgesia
Critical Illness
Mechanical Ventilation
Sedation
Interventions
DRUG
No Results Yet
18
Participants
Generate Real World Data On Tofacitinib Induction Therapy and Changes In Clinical and Patient Reported Outcomes.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-28
Completion:
2024-04-30
Conditions
Ulcerative Colitis
Interventions
OTHER
104
Participants
A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-02
Completion:
2027-05-06
Conditions
Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)
Interventions
DRUG
OTHER
No Results Yet
15
Participants
Impact Of Muscle Vibration On Gait Control
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-04
Completion:
2027-12-31
Conditions
Muscle
Interventions
DEVICE
No Results Yet
61
Participants
KZR-261 in Subjects With Advanced Solid Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-09-30
Completion:
2025-01-17
Conditions
Advanced/Metastatic Solid Tumor
Interventions
DRUG
6
Participants
Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-09-23
Completion:
2027-12-31
Conditions
Recurrent Glioblastoma
Recurrent Gliosarcoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
80
Participants
Separation Versus Integrated Approach in Combining ECMO With CRRT
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-01
Completion:
2025-03-10
Conditions
AKI
Interventions
DEVICE
No Results Yet
30
Participants
NEO100 and High-Grade Meningioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-01
Completion:
2026-12-30
Conditions
Residual, Progressive or Recurrent Grade II or III Meningioma
Interventions
DRUG
No Results Yet
26
Participants
Skin Fibrosis Analysis by Raman Spectroscopy in Systemic Sclerosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-08
Completion:
2023-07-21
Conditions
Validation of Raman Spectroscopy Usefulness in Systemic Sclerosis
No Results Yet
70
Participants
Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-09
Completion:
2023-10-03
Conditions
Ulcer
Anemia
Sickle Cell Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
195
Participants
Natural History of KSHV-Associated Multicentric Castleman s Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-11-17
Completion:
2034-01-01
Conditions
Multicentric Castleman s Disease
No Results Yet
315
Participants
Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-30
Completion:
2025-06-30
Conditions
ER-Positive HER2-Negative Breast Cancer
Interventions
DRUG
No Results Yet
48
Participants
Understanding Host-pathogen Interaction in the Respiratory Mucosa During Pregnancy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-02
Completion:
2023-09-27
Conditions
Pregnancy Related
Innate Inflammatory Response
Interventions
OTHER
No Results Yet
712
Participants
Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin or Who Refuse Cisplatin
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-08-05
Completion:
2026-04-30
Conditions
Muscle Invasive Bladder Cancer
Interventions
DRUG
PROCEDURE
No Results Yet
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