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Clinical Trials

Showing trials with last updates posted in 2025.

NCT04145557 | COMPLETED | NA
40 Participants

980nm Diode Laser in the Treatment of Periodontal Disease in Cardiac Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-08-12
Completion: 2024-12-30
Conditions
Myocardial Infarction Periodontal Diseases
Interventions
DEVICE
No Results Yet
NCT04127149 | COMPLETED | NA
166 Participants

Evaluation of Ultra-portable Ultrasound in General Practice

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-12-03
Completion: 2021-10-20
Conditions
Pneumonia Pleural Effusion Renal Colic Hepatic Colic or Cholecystitis Subcutaneous Abscess or Cyst Fracture of Long Bones Intra-uterine Pregnancy or Extra-uterine Pregnancy or Miscarriage Phlebitis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04112368 | COMPLETED | PHASE4
124 Participants

Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental Approach

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-09-15
Completion: 2024-08-01
Conditions
Suicidal Ideation
Interventions
DRUG
Results Available
NCT04093297 | RECRUITING | NA
300 Participants

Band Versus Ring for Tricuspid Regurgitation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2022-01-01
Completion: 2025-12-31
Conditions
Tricuspid Regurgitation
Interventions
PROCEDURE
No Results Yet
NCT04079166 | ACTIVE_NOT_RECRUITING | PHASE2
173 Participants

SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-08-19
Completion: 2027-01-31
Conditions
Malignant Melanoma Melanoma (Skin) Melanoma Stage III Melanoma Stage IV
Interventions
BIOLOGICAL
No Results Yet
NCT04077307 | RECRUITING | PHASE1
9 Participants

A Study in Leukemia Patients With Karonudib

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-12-03
Completion: 2026-12-30
Conditions
Leukemia
Interventions
DRUG
No Results Yet
NCT04070989 | TERMINATED | NA
100 Participants

Pinnacle RSA Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-12-03
Completion: 2023-06-12
Conditions
Osteoarthritis Degenerative Arthritis
Interventions
DEVICE
Results Available
NCT04053166 | COMPLETED | NA
56 Participants

Individualized Physical Activity and Carotid Plaque Instability

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-12-03
Completion: 2022-09-12
Conditions
Carotid Atherosclerosis
Interventions
DEVICE OTHER BIOLOGICAL
No Results Yet
NCT04037358 | COMPLETED | PHASE2
64 Participants

RAdium-223 and SABR Versus SABR for Oligometastatic Prostate Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-08-09
Completion: 2025-07-15
Conditions
Prostate Cancer
Interventions
DRUG RADIATION
Results Available
NCT04020029 | WITHDRAWN | NA
0 Participants

Leveraging Mindsets to Improve Health and Wellbeing in Patients With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-05
Completion: 2026-12-31
Conditions
Cancer
Interventions
OTHER
No Results Yet
NCT03993171 | COMPLETED | PHASE2
33 Participants

31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-12-19
Completion: 2025-05-27
Conditions
Multiple Sclerosis
Interventions
DRUG
No Results Yet
NCT03992404 | ACTIVE_NOT_RECRUITING | PHASE3
603 Participants

Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-09-16
Completion: 2025-06-19
Conditions
Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury
Interventions
DRUG
No Results Yet
NCT03985189 | COMPLETED | PHASE1
14 Participants

Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-04-29
Completion: 2025-01-15
Conditions
Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma
Interventions
DRUG
No Results Yet
NCT03974828 | WITHDRAWN | NA
0 Participants

Telemedicine Notifications With Machine Learning for Postoperative Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-07-01
Completion: 2028-07-01
Conditions
Surgery--Complications Perioperative/Postoperative Complications Acute Kidney Injury Hospital Mortality
Interventions
DEVICE
No Results Yet
NCT03973996 | COMPLETED | NA
46 Participants

Gut-level Antiinflammatory Activities of Green Tea in Metabolic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-07-01
Completion: 2021-03-01
Conditions
Dysbiosis Endotoxemia Metabolic Syndrome Inflammation
Interventions
DIETARY_SUPPLEMENT
Results Available
NCT03964090 | ACTIVE_NOT_RECRUITING | PHASE2
48 Participants

Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-06-27
Completion: 2027-07-01
Conditions
Central Nervous System Lymphoma Secondary Central Nervous System Lymphoma
Interventions
DRUG
No Results Yet
NCT03959761 | COMPLETED | PHASE1/PHASE2
22 Participants

Tolerance of Intraperitoneal (IP) Nivolumab After Extensive Debulking Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Ovarian Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-10-17
Completion: 2022-10-03
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT03904693 | COMPLETED | PHASE3
187 Participants

Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-07-29
Completion: 2022-08-23
Conditions
Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
Interventions
DRUG
Results Available
NCT03904316 | WITHDRAWN | PHASE4
0 Participants

Use of Biodesign® Otologic Graft in Tympanoplasty

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2018-10-03
Completion: 2022-07-01
Conditions
Tympanic Membrane Perforation
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT03902938 | WITHDRAWN | PHASE4
0 Participants

Use of Biodesign® Otologic Graft in Canal Wall Down Mastoidectomy: A Prospective, Randomized Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2018-10-02
Completion: 2022-07-01
Conditions
Otologic Disease
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT03887988 | ACTIVE_NOT_RECRUITING
300 Participants

Orbital Fractures Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2019-11-01
Completion: 2026-03-31
Conditions
Orbital Fractures Blow Out Fracture of Orbit
Interventions
PROCEDURE OTHER
No Results Yet
NCT03861117 | COMPLETED | NA
98 Participants

Pressure Support and Positive End Expiratory Pressure During Spontaneous Breathing Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-05-10
Completion: 2023-06-01
Conditions
Critically Ill Adult Patients With Difficult Weaning
Interventions
PROCEDURE
No Results Yet
NCT03840733 | ENROLLING_BY_INVITATION
60 Participants

Linking Temporal Patterns of Modifiable Behaviors to Weight Loss Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2019-01-07
Completion: 2026-01-31
Conditions
Obesity Weight Change, Body
No Results Yet
NCT03830229 | RECRUITING
1000 Participants

Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other Genes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2019-03-13
Completion: 2026-07-06
Conditions
Mesothelioma Families
No Results Yet
NCT03818087 | ACTIVE_NOT_RECRUITING
253 Participants

Elevate! : An Elderly Breast Cancer Cohort Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2019-02-19
Completion: 2027-12-01
Conditions
Breast Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT03791580 | WITHDRAWN | NA
0 Participants

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-02-01
Completion: 2019-08-01
Conditions
Fall Congestive Heart Failure Chronic Kidney Failure Adverse Drug Event
Interventions
BEHAVIORAL
No Results Yet
NCT03753334 | ACTIVE_NOT_RECRUITING | PHASE2
39 Participants

Effects of EPA in Men With Biochemical Recurrence or Progression of Prostate Cancer.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2017-07-10
Completion: 2023-12-12
Conditions
Prostate Cancer
Interventions
COMBINATION_PRODUCT DIETARY_SUPPLEMENT
No Results Yet
NCT03739073 | COMPLETED | NA
101 Participants

Can we Predict COronary Resistance By EYE Examination ? (COREYE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2018-10-04
Completion: 2024-03-20
Conditions
Coronary Artery Disease
Interventions
OTHER
No Results Yet
NCT03738592 | COMPLETED | NA
36 Participants

Spatial Hearing Perception in Bilateral Cochlear Implant Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-01-24
Completion: 2019-11-18
Conditions
Cochlear Impant Children
Interventions
OTHER
No Results Yet
NCT03651206 | RECRUITING | PHASE2/PHASE3
138 Participants

Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-07-15
Completion: 2027-06-30
Conditions
Ovarian Carcinosarcoma Endometrial Carcinosarcoma
Interventions
DRUG COMBINATION_PRODUCT
No Results Yet
NCT03642639 | COMPLETED | NA
809 Participants

A Study to Look at Performance of MICRUSFRAME and GALAXY Coils for the Treatment of Intracranial Aneurysms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2018-08-23
Completion: 2025-06-12
Conditions
Aneurysms
Interventions
DEVICE
No Results Yet
NCT03635333 | COMPLETED | PHASE1
130 Participants

Effects of E-Cigarette Flavors on Adults TCORS 2.0

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-05-14
Completion: 2023-07-12
Conditions
Nicotine Use Disorder
Interventions
DRUG
Results Available
NCT03631043 | COMPLETED | EARLY_PHASE1
30 Participants

Personalized Vaccine in Treating Patients With Smoldering Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2018-12-21
Completion: 2025-12-10
Conditions
Smoldering Plasma Cell Myeloma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT03615014 | COMPLETED | NA
460 Participants

Predictive Factors of PTSD in Adults Admitted to an Emergency Service

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-02-11
Completion: 2019-10-09
Conditions
Post Traumatic Stress Disorder Psychiatric Issue
Interventions
OTHER
No Results Yet
NCT03614949 | ACTIVE_NOT_RECRUITING | PHASE2
21 Participants

SBRT and Atezolizumab in the Management of Recurrent, Persistent, or Metastatic Cervical Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2019-01-29
Completion: 2028-10-31
Conditions
Cervical Cancer Cervical Cancer Recurrent Cervical Cancer Metastatic
Interventions
RADIATION DRUG
No Results Yet
NCT03573752 | COMPLETED | NA
60 Participants

Study of Outpatient Management for Promontofixation by Laparoscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2018-07-26
Completion: 2021-12-30
Conditions
Pelvic Organ Prolapse
Interventions
OTHER
No Results Yet
NCT03570333 | COMPLETED | NA
7 Participants

Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2018-09-17
Completion: 2019-12-30
Conditions
Gingival Recession Lack of Keratinized Gingiva (Disorder)
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03543371 | COMPLETED
200 Participants

Neuropsychological Outcome After Cardiac Arrest

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2018-07-13
Completion: 2021-01-11
Conditions
Heart Arrest, Out-Of-Hospital Hypoxia-Ischemia, Brain Cognition Disorders Psychological Distress Fatigue Insomnia
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03533673 | ACTIVE_NOT_RECRUITING | PHASE1
7 Participants

AAV2/8-LSPhGAA (ACTUS-101) in Late-Onset Pompe Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2018-12-17
Completion: 2022-09-30
Conditions
Pompe Disease
Interventions
BIOLOGICAL
No Results Yet
NCT03509467 | COMPLETED | NA
2054 Participants

Using MC1R Genotype to Impact Melanoma Risk Behavior

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2015-08-03
Completion: 2021-02-19
Conditions
Melanoma (Skin) Squamous Cell Carcinoma Squamous Cell Cancer Skin Cancer Basal Cell Carcinoma Basal Cell Cancer
Interventions
BEHAVIORAL OTHER
Results Available
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