Predictive Factors of PTSD in Adults Admitted to an Emergency Service

NCT ID: NCT03615014

Last Updated: 2025-12-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 460 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-02-11
• Study Completion Date: 2019-10-09

Brief Summary

After trauma or stress factor like death exposition, serious injuries or sexual violence, some patients may develop stress reaction characterized by the presence of various symptoms among different categories (reviviscence, negative humor, dissociates symptoms, occasion, hypervigilance). In the month following trauma, the investigators speak of acute stress reaction (ASR) when symptoms are present during at least three days. If symptoms are present one month after trauma, then it is a post-traumatic stress disorder (PTSD).

Among patients visiting emergency after latest trauma, quite a few is in acute stress reaction. However, this reaction is often incorrectly identified by healthcare team, due to lack of oriented medical examination, patients visiting about other complaints (pain, insomnia) and not expressing clearly the trauma context. Yet, it is know that acute stress reaction occurrence and existence of dissociate symptoms after trauma confrontation is considerably predictive of the eventual post-traumatic stress disorder occurrence.

The identification of risk population of post-traumatic stress disorder is not the subject of any particular structured procedure in emergency services while early care of these patients may allow limiting post-traumatic stress disorder occurrence and associate consequences. Previous works on the subject having exclusively targeted some trauma subgroups or some predictive factors subtypes, investigators propose here biopsychosocial global approach that can weight the impact of each parameters.

In this study, investigators aim at determining predictive biopsychosocial factors of the post-traumatic stress disorder occurrence at 3 months in patients visiting emergency after latest trauma (less than one month old) and identified as "high-risk" to develop post-traumatic stress disorder (moderate or high).

Conditions

Post Traumatic Stress Disorder; Psychiatric Issue

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Patients having trauma

Adults patients having trauma in the month before visiting emergency will fill questionnaires

Group Type: OTHER

Filling questionnaires

Intervention Type: OTHER

Questionnaires will be submitted to patients during their visit to emergency service and 3 months later to evaluate the prevalence of Post Traumatic Stress Disorder and to identify predictive biopsychosocial factors

Interventions

Filling questionnaires

Questionnaires will be submitted to patients during their visit to emergency service and 3 months later to evaluate the prevalence of Post Traumatic Stress Disorder and to identify predictive biopsychosocial factors

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Man or woman aged between 18 and 70
• Admitted in an emergency service after a trauma less than one month old, defined by death exposition or death threat, serious injury or sexual violence, by one or several of the following;

• Being directly exposed ;
• Being direct witness of traumatic event that occurred to other people;
• Hearing that traumatic event arrived to close family member or close friend. In the case of death penalty or death threat of a family member or a friend, events must have been violent or accidental.
• Being exposed repeatedly or extremely to aversive characteristics of trauma events (for example: first line actors gathering human remains, cops exposed several times to kid sexual abuse explicit fact).
• Written informed-consent
• Affiliation to the French social security scheme or beneficiary of a similar scheme

Exclusion Criteria

• Patient not understanding French language
• Patient under guardianship
• Clinical instability making impossible the realization of questionnaires (for example: agitation, vital risk, disorders of consciousness…)

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hospices Civils de Lyon

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Clémence BIED, Dr

Role: PRINCIPAL_INVESTIGATOR

Hospices Civils de Lyon

Locations

CHU Clermont - Hôpital G Montpied - Urgences Psychiatriques et Médecine d'urgence

Clermont-Ferrand, , France

CH St Joseph St Luc - Urgences Psychiatriques et Médecine d'urgence

Lyon, , France

Hôpital Edouard Herriot - Urgences Psychiatrique et Médecine d'urgence

Lyon, , France

Centre Hospitalier Lyon Sud - Urgences psychiatriques

Pierre-Bénite, , France

CHU St Etienne - Hôpital Nord - Urgences Psychiatriques

Saint-Priest-en-Jarez, , France

Countries

France

References

Wafa MH, Viprey M, Magaud L, Haesebaert J, Leaune E, Poulet E, Bied C, Schott AM. Identification of biopSychoSocial factors predictive of post-traUmatic stress disorder in patients admitted to the Emergency department after a trauma (ISSUE): protocol for a multicenter prospective study. BMC Psychiatry. 2019 May 30;19(1):163. doi: 10.1186/s12888-019-2154-z.

Reference Type: RESULT

PMID: 31146712 (View on PubMed)

Other Identifiers

69HCL18_0142

Identifier Type: -

Identifier Source: org_study_id