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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06603883 | RECRUITING | PHASE2/PHASE3
60 Participants

Efficacy of Fecal Microbiota Transplantation in ICU Patients With Gastrointestinal Dysfunction-induced Enteral Nutrition Intolerance

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-19
Completion: 2026-10-31
Conditions
Gastrointestinal Dysfunction-induced Enteral Nutrition Intolerance
Interventions
BIOLOGICAL
No Results Yet
NCT06595927 | COMPLETED | NA
29 Participants

Clinical Signs and Changes in Cervical Muscles Activity Evaluated by Magnetic Resonance Imaging During an Endurance Test

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-11-01
Completion: 2025-01-31
Conditions
Neck Pain Motor Activity
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06593847 | COMPLETED | NA
1542 Participants

Multisite Virtual Reality Intervention for Speech Anxiety

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-08
Completion: 2025-07-23
Conditions
Public Speaking Speech Anxiety
Interventions
BEHAVIORAL
No Results Yet
NCT06590480 | NO_LONGER_AVAILABLE

An Expanded Access Program for VO (RP1) in Combination With Nivolumab in Patients With Advanced Melanoma

Study Type: EXPANDED_ACCESS
Last Updated: 2025-12-18
Conditions
Advanced Melanoma
Interventions
BIOLOGICAL
No Results Yet
NCT06589986 | RECRUITING | PHASE3
400 Participants

A Study to Assess the Efficacy and Safety of Afimkibart (Also Known as RO7790121) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-09-17
Completion: 2027-06-30
Conditions
Moderately to Severely Active Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT06583239 | NOT_YET_RECRUITING | NA
555 Participants

Hub-Based Engagement Navigator Service to Reduce CSC Disengagement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-06-01
Completion: 2029-07-31
Conditions
Disengagement
Interventions
OTHER
No Results Yet
NCT06583018 | ACTIVE_NOT_RECRUITING | NA
84 Participants

Mindfulness-based Lifestyle Modification Programme for Caregivers of People With Neurodegenerative Disorders: A Pilot Randomised Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-09-06
Completion: 2026-01-31
Conditions
Caregiver
Interventions
BEHAVIORAL DEVICE
No Results Yet
NCT06579092 | COMPLETED | PHASE2
310 Participants

Effects of AZD5004 in Adults Who Are Living With Obesity or Overweight With at Least 1 Weight-related Comorbidity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-08
Completion: 2025-11-21
Conditions
Obesity or Overweight
Interventions
DRUG
No Results Yet
NCT06571383 | ACTIVE_NOT_RECRUITING | PHASE4
500 Participants

STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-09-17
Completion: 2028-11-15
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06568042 | ACTIVE_NOT_RECRUITING | PHASE2
450 Participants

Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-08-22
Completion: 2026-06-30
Conditions
Neuropathic Pain Distal Sensory Polyneuropathy
Interventions
DRUG
No Results Yet
NCT06560333 | WITHDRAWN | PHASE3
0 Participants

iSGLT2 Inhibitor and a iDPP -4 Inhibitor in Treatment of Type 2 Diabetes Mellitus in Patients Treated With Metformin (TRIAD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-11-30
Completion: 2027-04-30
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT06560229 | ACTIVE_NOT_RECRUITING | NA
400 Participants

Giving Resources to lOw-income Children to Enhance RecoverY

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-09-27
Completion: 2026-07-31
Conditions
Discharged Pediatric Patients and Their Families
Interventions
OTHER
No Results Yet
NCT06556160 | COMPLETED | NA
19 Participants

Fundamental and Clinical Study of Cochlear Synaptopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-03-21
Completion: 2025-07-16
Conditions
Hearing Loss
Interventions
PROCEDURE
No Results Yet
NCT06551142 | RECRUITING | PHASE1
590 Participants

A Study of GSK5764227 in Participants With. Advanced Solid Tumors (EMBOLD PanTumor-101)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-09-30
Completion: 2026-09-24
Conditions
Neoplasms
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06551038 | RECRUITING | NA
240 Participants

Evaluating Primary Suicide Prevention in Adolescents With Risk Factors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-03-11
Completion: 2027-05-30
Conditions
Suicide Prevention
Interventions
BEHAVIORAL
No Results Yet
NCT06548360 | RECRUITING | PHASE3
180 Participants

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-24
Completion: 2026-08-10
Conditions
NonSegmental Vitiligo
Interventions
DRUG
No Results Yet
NCT06545669 | ACTIVE_NOT_RECRUITING | PHASE4
30 Participants

C-Raven, a Virtual Tobacco Cessation Intervention in the Community

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-30
Completion: 2025-10-17
Conditions
Tobacco Dependence
Interventions
BEHAVIORAL DRUG OTHER
No Results Yet
NCT06545071 | COMPLETED | PHASE1
17 Participants

Autonomous Digital CBT Intervention for Opioid Use Disorder in Individuals With Co-Occurring Internalizing Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-21
Completion: 2025-12-14
Conditions
Opioid Use Disorder Anxiety Depression
Interventions
BEHAVIORAL
No Results Yet
NCT06545058 | COMPLETED
2086 Participants

Safety Profile of Ropivacaine in Dorsal Penile Nerve Block for Male Circumcision: a Large Cohort Study in Children

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2000-01-01
Completion: 2021-12-31
Conditions
Pain Necrosis
Interventions
PROCEDURE
No Results Yet
NCT06544265 | RECRUITING | PHASE1
18 Participants

SynKIR-310 for Relapsed/Refractory B-NHL

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-11-01
Completion: 2028-09-30
Conditions
B Cell Lymphoma NHL, Adult Mantle Cell Lymphoma Relapsed Non-Hodgkin Lymphoma Refractory Non-Hodgkin Lymphoma Aggressive B-Cell Non-Hodgkin Lymphoma Indolent B-Cell Non-Hodgkin Lymphoma Follicular Lymphoma Marginal Zone Lymphoma DLBCL - Diffuse Large B Cell Lymphoma HGBL With MYC and BCL2 and/or BCL6 Rearrangements High-grade B-cell Lymphoma Diffuse Large B Cell Lymphoma Large B-cell Lymphoma T-Cell/Histiocyte Rich Lymphoma Non-hodgkin Lymphoma,B Cell Primary Mediastinal Large B-cell Lymphoma (PMBCL) Epstein-Barr Virus Positive DLBCL, Nos Follicular Lymphoma Grade 3B DLBCL (Diffuse Large B-Cell Lymphoma) Associated With Chronic Inflammation High Grade B-Cell Lymphoma, Not Otherwise Specified Follicular Lymphoma Grade 3 Marginal Zone Splenic Lymphoma DLBCL
Interventions
BIOLOGICAL
No Results Yet
NCT06544213 | ACTIVE_NOT_RECRUITING | NA
24 Participants

A 60 Days Head Down Tilt Bedrest With Artificial Gravity and Cycling Exercise on 24 Healthy Male (BRACE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-02-06
Completion: 2024-04-20
Conditions
Simulated Microgravity by Head Down Tilt Bedrest Weightlessness
Interventions
BEHAVIORAL
No Results Yet
NCT06537310 | ACTIVE_NOT_RECRUITING | PHASE1
34 Participants

A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-09-16
Completion: 2029-06-19
Conditions
Cancer-Neoplasms
Interventions
DRUG
No Results Yet
NCT06517836 | COMPLETED | NA
1284 Participants

Automated Screening Device to Detect MTMROP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-20
Completion: 2025-01-01
Conditions
Retinopathy of Prematurity ROP
Interventions
DEVICE
No Results Yet
NCT06514898 | ACTIVE_NOT_RECRUITING | PHASE1
12 Participants

Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-05-05
Completion: 2027-09-01
Conditions
Recurrent Group 3 Medulloblastoma Recurrent Group 4 (Non-SHH/Non-WNT) Medulloblastoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06513026 | NOT_YET_RECRUITING | NA
40 Participants

Milk for Diabetes Prevention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-02-28
Completion: 2028-02-29
Conditions
Lactose Intolerance Lactose Intolerant Lactase Persistence Pre-Diabetes Diabetes Mellitus, Type 2
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06509906 | TERMINATED | PHASE1
3 Participants

M9466 in Combination With Topoisomerase 1 Inhibitors-based Regimens in Advanced Solid Tumors and Colorectal Cancer (DDRiver 511)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-08
Completion: 2025-12-02
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06508931 | RECRUITING | PHASE2
31 Participants

Safety and Efficacy Study of Zamtocabtagene Autoleucel (MB-CART2019.1) in Pediatric Patients With R/R B-Cell Neoplasms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-04
Completion: 2029-12-31
Conditions
B-Cell Neoplasm
Interventions
DRUG
No Results Yet
NCT06503354 | COMPLETED
29 Participants

Gait Metric Validation of the Cionic Neural Sleeve

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-07-08
Completion: 2025-12-01
Conditions
Validation Study
Interventions
DEVICE
No Results Yet
NCT06498245 | COMPLETED
500 Participants

Early Abdominal Wall Prosthesis Infections: Epidemiology, Risk Factors and Factors Linked to Recovery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2023-10-16
Completion: 2024-10-16
Conditions
Abdominal Wall Prosthesis Infections
No Results Yet
NCT06494176 | RECRUITING | NA
250 Participants

Virtual Reality Exposure for Dental Fear

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-08-09
Completion: 2026-12-31
Conditions
Dental Fear
Interventions
BEHAVIORAL
No Results Yet
NCT06489886 | ACTIVE_NOT_RECRUITING | NA
19 Participants

Nutrient and Hormonal Profile and Muscle Protein Synthesis Response to Consuming Chicken

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-11
Completion: 2026-06-01
Conditions
Effect of Food
Interventions
OTHER
No Results Yet
NCT06488534 | COMPLETED | NA
15 Participants

Intracolonic FODMAP Infusion in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-06-26
Completion: 2024-11-13
Conditions
Irritable Bowel Syndrome
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06485687 | ACTIVE_NOT_RECRUITING | NA
15 Participants

Low Intensity Focused Ultrasound for Binge Eating Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-31
Completion: 2026-12-31
Conditions
Binge-Eating Disorder
Interventions
DEVICE
No Results Yet
NCT06478693 | RECRUITING | PHASE1
70 Participants

A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-07-01
Completion: 2027-12-31
Conditions
Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
NCT06471660 | COMPLETED
219 Participants

Family Caregiver Online Survey (Dementia and Swallowing Difficulties)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2023-11-07
Completion: 2025-07-12
Conditions
Dementia Dysphagia Dementia Alzheimers Dementia, Vascular Dementia, Mixed Dementia With Lewy Bodies Dementia Frontal Dementia, Mild Dementia Moderate Dementia Severe Parkinson Disease Dementia Dementia Frontotemporal
No Results Yet
NCT06460350 | COMPLETED | NA
156 Participants

NEUROCUPLE™ in TKA Patients to Enhance Pain Management

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-09-25
Completion: 2025-07-18
Conditions
Total Knee Arthroplasty
Interventions
DEVICE
No Results Yet
NCT06459427 | NOT_YET_RECRUITING | NA
142 Participants

A Multicenter, RAndomIzed, coNtrolled, umBrella Trial fOr Minimally Invasive Neurosurgery With AI-assisted Robotic guidanCe for Hemorrhagic Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-04-30
Completion: 2027-12-31
Conditions
Brain Stem Hemorrhage Robotic Surgical Procedures
Interventions
PROCEDURE DRUG
No Results Yet
NCT06457230 | RECRUITING | NA
70 Participants

Paired-pulse rTMS Treatment for Methamphetamine Use Disorder Based on the mPFC-Cerebellum

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-24
Completion: 2026-05-31
Conditions
Methamphetamine Use Disorder
Interventions
DEVICE
No Results Yet
NCT06456008 | RECRUITING
500 Participants

Prospective Registery of Smell/Taste Clinic Ear/Nose/Throat

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2022-12-06
Completion: 2027-01-01
Conditions
Olfactory Disorder Taste Disorders Smell Dysfunction Smell Disorder
Interventions
OTHER
No Results Yet
NCT06455202 | RECRUITING | PHASE3
915 Participants

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-07-19
Completion: 2026-10-31
Conditions
Chronic Spontaneous Urticaria
Interventions
BIOLOGICAL
No Results Yet
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