Evaluating Primary Suicide Prevention in Adolescents With Risk Factors

NCT ID: NCT06551038

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

240 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-11

Study Completion Date

2028-09-30

Brief Summary

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Suicide is one of the main causes of death among teenagers. Because it is preventable, primary prevention of suicide has become a public health priority, with encouraging results in promoting suicide awareness and reducing suicidal thoughts among adolescents. However, the lack of studies conducted among vulnerable populations (i.e., marginalised, disengaged and disadvantaged) is a major gap, even though these populations present an increased risk of suicidal behaviour.

The aim of this project is to test the effectiveness of a brief primary suicide prevention intervention for vulnerable adolescents, using a randomised controlled trial. Vulnerable adolescents include those 1) detained in juvenile detention centres, 2) at risk of dropping out of school, 3) undergoing treatment for psychiatric disorders, 4) belonging to a sexual or gender diversity, 5) affected by chronic conditions, or 6) with relational/familial problems. The main aim is to test the effectiveness of the intervention on a composite measure of suicide awareness, psychological distress and suicidal thoughts. The project will also explore other issues that present challenges for vulnerable populations: access to primary suicide prevention and non-response bias. The study will provide relevant results to address the current lack of high-quality evidence for primary suicide prevention in adolescents.

Detailed Description

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Conditions

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Suicide Prevention

Keywords

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Suicide Primary prevention Vulnerable adolescents Psychological distress

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Primary suicide prevention intervention

The framework of the primary suicide prevention intervention is psychoeducation. The intervention lasts for 90 minutes and is conducted in groups of 5 to 15 (on average 10) participants. It provides general information on suicidal behaviors, information about facts and myths about suicide, identification of risk factors and warning signs of suicidal behaviors, and information on ways to seek for help and get support for themselves and others in the canton. The intervention includes a lecture, group discussions based on case examples, and a quiz on facts and myths about suicide. It is conducted by a trained staff member with the support of a psychologist trained in suicide prevention for children and adolescents. It follows a standardized format.

Group Type EXPERIMENTAL

Primary suicide prevention intervention

Intervention Type BEHAVIORAL

Psychoeducation workshop

Art-based control intervention

The control intervention will be an art-based activity, a workshop on slam poetry. At the end of the study, participants will get a flyer containing information on suicide prevention with the participants of the control group. Therefore, they will have a low-threshold intervention.

Group Type ACTIVE_COMPARATOR

Art-based control intervention

Intervention Type BEHAVIORAL

Slam poetry workshop

Interventions

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Primary suicide prevention intervention

Psychoeducation workshop

Intervention Type BEHAVIORAL

Art-based control intervention

Slam poetry workshop

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Vulnerable adolescents defined as being: 1) detained in juvenile detention centers, 2) disconnected from school, 3) in treatment for psychiatric disorders, 4) belonging to a sexual or gender minority, 5) affected by chronic conditions, or 6) with relational/familial problems.
* Age 14 to 25 years old.
* Good knowledge of French.
* Accepting to sign the informed consent.

Exclusion Criteria

* The medical/educational staff considers that the intervention will interfere with appropriate management of acute psychiatric disorder or may cause harm to self or other.
* Being enrolled in another suicide prevention intervention during the study period.
Minimum Eligible Age

14 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stephanie Baggio

OTHER

Sponsor Role lead

Responsible Party

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Stephanie Baggio

Associate Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Stéphanie Baggio, Prof.

Role: PRINCIPAL_INVESTIGATOR

Institute of Primary Health Care (BIHAM), University of Bern

Locations

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Dialogai et Totem

Geneva, Canton of Geneva, Switzerland

Site Status RECRUITING

Programme ForMe (anciennement SEMO) et dispositif ProPULSE

Plan-les-Ouates, Canton of Geneva, Switzerland

Site Status RECRUITING

Centre de Détention et d'Observation La Clairière

Vernier, Canton of Geneva, Switzerland

Site Status RECRUITING

Programme Intégration et Formation Professionnelle

Vernier, Canton of Geneva, Switzerland

Site Status RECRUITING

Agnodice

Lausanne, Canton of Vaud, Switzerland

Site Status RECRUITING

Vogay

Lausanne, Canton of Vaud, Switzerland

Site Status RECRUITING

Centre Thérapeutique de Jour pour Adolescents

Lausanne, Canton of Vaud, Switzerland

Site Status RECRUITING

Unité de Soins Psychiatriques Fermée pour Mineurs

Lausanne, Canton of Vaud, Switzerland

Site Status RECRUITING

Établissement de Détention pour mineurs et jeunes adultes Les Léchaires

Palézieux, Canton of Vaud, Switzerland

Site Status RECRUITING

Centre éducatif fermé de Pramont

Sierre, Valais, Switzerland

Site Status RECRUITING

CAP Formations, Cité des Métiers

Geneva, , Switzerland

Site Status RECRUITING

Unité de Liaison Ambulatoire et Hospitalière, Service de psychiatrie de l'enfant et de l'adolescent, HUG

Geneva, , Switzerland

Site Status RECRUITING

Foyers de Gilly

Grand-Lancy, , Switzerland

Site Status RECRUITING

Foyer de Chailly

Lausanne, , Switzerland

Site Status RECRUITING

Ren'Fort

Lausanne, , Switzerland

Site Status RECRUITING

Foyer La Pommeraie

Lonay, , Switzerland

Site Status RECRUITING

Service des Parcours Individualisé

Onex, , Switzerland

Site Status RECRUITING

Le Repuis

Petit Lancy, , Switzerland

Site Status RECRUITING

Astural, Parcours A2mains

Thônex, , Switzerland

Site Status RECRUITING

Countries

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Switzerland

Central Contacts

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Stéphanie Baggio, Prof.

Role: CONTACT

Phone: +41316846774

Email: [email protected]

Facility Contacts

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Nadjeda Lambert

Role: primary

Nadejda Lambert

Role: primary

Patrick Heller, MD

Role: primary

Nadejda Lambert

Role: primary

Nadejda Lambert

Role: primary

Nadejda Lambert

Role: primary

Sébastien Urben, Dr.

Role: primary

Sébastien Urben, Dr.

Role: primary

Patrick Heller, MD

Role: primary

Patrick Heller, MD

Role: primary

Stéphanie Baggio, PhD

Role: backup

Nadejda Lambert

Role: primary

Santiago Peregalli

Role: primary

Patrick Heller, MD

Role: primary

Patrick Heller, MD

Role: primary

Nadejda Lambert

Role: primary

Patrick Heller, MD

Role: primary

Nadejda Lambert

Role: primary

Nadejda Lambert

Role: primary

Nadejda Lambert

Role: primary

References

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Baggio S, Bailey E, Edan A, Heller P, Kapp C, Lambert N, Michaud L, Mundt AP, Nsingi N, Perez S, Peregalli S, Piguet C, Piotrowski C, Prutyanova Y, Rumley M, Sapin M, Urben S, Iglesias K. Evaluating primary suicide prevention in adolescents with risk factors (ESPAIR): study protocol for a cluster-randomized controlled trial. Trials. 2025 Nov 24;26(1):537. doi: 10.1186/s13063-025-09266-y.

Reference Type DERIVED
PMID: 41286939 (View on PubMed)

Other Identifiers

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2024-01208

Identifier Type: -

Identifier Source: org_study_id