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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06453265 | COMPLETED | PHASE1
48 Participants

A Study to Assess the Abuse Potential of Intranasal Cebranopadol

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-28
Completion: 2024-11-06
Conditions
Abuse, Drug
Interventions
DRUG
No Results Yet
NCT06453213 | ACTIVE_NOT_RECRUITING | PHASE4
49 Participants

Open-label Study of Cenobamate Monotherapy in Adult Subjects With Newly Diagnosed or Recurrent Partial-Onset Epilepsy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-14
Completion: 2027-05-26
Conditions
Focal Onset Seizure
Interventions
DRUG
No Results Yet
NCT06451042 | COMPLETED
11 Participants

FET-PET/MRI Based Treatment Planning for Glioblastoma Multiforme in Post-Surgical Patients (FET-TREAT)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-07-01
Completion: 2025-12-08
Conditions
Glioblastoma Multiforme
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06450444 | RECRUITING | NA
62 Participants

The RECLAIM Study.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-24
Completion: 2026-04-01
Conditions
Chronic Migraine High Frequency Episodic Migraine
Interventions
DEVICE
No Results Yet
NCT06447662 | RECRUITING | PHASE1
330 Participants

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-27
Completion: 2027-09-10
Conditions
Colorectal Neoplasms Carcinoma, Non-Small-Cell Lung Carcinoma, Pancreatic Ductal
Interventions
DRUG COMBINATION_PRODUCT
No Results Yet
NCT06446986 | COMPLETED
70 Participants

Dual Task Effect in Adolescent Idiopathic Scoliosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-06
Completion: 2025-02-26
Conditions
Scoliosis Idiopathic
Interventions
OTHER
No Results Yet
NCT06445270 | NOT_YET_RECRUITING | NA
100 Participants

Lifestyle Interventions to Improve Glycemic Parameters and Reduce Gestational Diabetes in High-risk Pregnant Individuals

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-08-31
Completion: 2030-08-31
Conditions
Gestational Diabetes Pregnancy Complications
Interventions
BEHAVIORAL
No Results Yet
NCT06442761 | RECRUITING | PHASE1
15 Participants

SCD Stem Cell Mobilization and Apheresis Using Motixafortide

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-11-14
Completion: 2028-01-31
Conditions
Sickle Cell Disease
Interventions
DRUG
No Results Yet
NCT06441812 | RECRUITING | PHASE2
200 Participants

A Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-07-19
Completion: 2028-09-30
Conditions
Eosinophilic Asthma Patients
Interventions
DRUG
No Results Yet
NCT06438471 | RECRUITING | PHASE1
36 Participants

Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-04-15
Completion: 2026-12-31
Conditions
Spinal Cord Injuries Neuropathic Pain
Interventions
DRUG
No Results Yet
NCT06429501 | RECRUITING | PHASE2
70 Participants

Local Anesthesia for Facial Fractures

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-04-02
Completion: 2026-02-01
Conditions
Pain Management
Interventions
DRUG
No Results Yet
NCT06422884 | RECRUITING | PHASE2
200 Participants

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-11-15
Completion: 2026-10-31
Conditions
Idiopathic Pulmonary Fibrosis Progressive Fibrosing Interstitial Lung Disease
Interventions
DRUG
No Results Yet
NCT06419439 | RECRUITING | PHASE2
44 Participants

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-03
Completion: 2028-12-01
Conditions
Chronic Low Back Pain Depression
Interventions
DRUG BEHAVIORAL
No Results Yet
NCT06415357 | ACTIVE_NOT_RECRUITING | NA
164 Participants

Zambia Healthy Choices Project for Emerging Adults Living With HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-04-20
Completion: 2026-03-31
Conditions
Pre-Exposure Prophylaxis
Interventions
BEHAVIORAL
No Results Yet
NCT06412757 | RECRUITING | PHASE3
278 Participants

Silexan in the Treatment Of Posttraumatic Stress Disorder Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-08-26
Completion: 2027-05-31
Conditions
Post Traumatic Stress Disorder
Interventions
DRUG OTHER
No Results Yet
NCT06411691 | RECRUITING | PHASE1
54 Participants

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-06-24
Completion: 2028-03-01
Conditions
Colorectal Cancer Pancreatic Cancer
Interventions
DRUG
No Results Yet
NCT06410807 | COMPLETED
23 Participants

Development of Web-Based Mind-Body Trainings for Adults With Subjective Concerns

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-11-01
Completion: 2025-05-02
Conditions
Aging Focus Groups
Interventions
OTHER
No Results Yet
NCT06407934 | ACTIVE_NOT_RECRUITING | PHASE3
1541 Participants

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-05-08
Completion: 2026-06-29
Conditions
Dermatitis Atopic
Interventions
DRUG
No Results Yet
NCT06404333 | COMPLETED | PHASE2
13 Participants

Evaluating Pediatric Ivermectin in Children Under 15 kg (EPIC-15)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-25
Completion: 2025-11-30
Conditions
Scabies
Interventions
DRUG
No Results Yet
NCT06403137 | COMPLETED | NA
51 Participants

Plant Protein Blend and Milk Protein Supplements in Older Individuals

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-26
Completion: 2025-12-05
Conditions
Sarcopenia Skeletal Muscle Atrophy Protein Malnutrition
Interventions
DIETARY_SUPPLEMENT BEHAVIORAL
No Results Yet
NCT06386172 | COMPLETED | NA
65 Participants

Electronic Decision-support System to Improve Detection and Care of Patients With Chronic Kidney Disease in Stockholm

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-09-09
Completion: 2025-09-30
Conditions
Chronic Kidney Diseases
Interventions
OTHER
No Results Yet
NCT06384170 | SUSPENDED
12 Participants

Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-03
Completion: 2026-01-31
Conditions
Chronic Pain Spasticity as Sequela of Stroke Upper Motor Neuron Lesion
Interventions
DEVICE
No Results Yet
NCT06372860 | COMPLETED | NA
43 Participants

DPP Feasibility Study of Breastfeeding - eMOMS 2.0

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-04-30
Completion: 2025-08-31
Conditions
Overweight or Obesity Pregnancy
Interventions
BEHAVIORAL
No Results Yet
NCT06369948 | COMPLETED | NA
60 Participants

Quality Of Recovery After Pericapsular Nerve Group (PENG) Block For Hip Hemiarthroplasty Under Spinal Anesthesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-03-01
Completion: 2024-09-01
Conditions
Hip Hemiarthroplasty
Interventions
PROCEDURE DRUG
No Results Yet
NCT06366750 | ACTIVE_NOT_RECRUITING | PHASE2
140 Participants

A Study of Barzolvolimab in Patients With Prurigo Nodularis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-04-12
Completion: 2026-06-30
Conditions
Prurigo Nodularis
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06365853 | RECRUITING | PHASE2
100 Participants

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-07-29
Completion: 2026-06-30
Conditions
Recurrent Ovarian Cancer Folate Receptor-Alpha Positive
Interventions
DRUG
No Results Yet
NCT06364371 | RECRUITING
106 Participants

Dynamic Multi-omics Integration Model to Predict Neoadjuvant Therapy Response in Locally Advanced Rectal Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-01
Completion: 2027-06-01
Conditions
Predictive Cancer Model Pathologic Complete Response
Interventions
OTHER
No Results Yet
NCT06359379 | TERMINATED | PHASE2
30 Participants

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-09-02
Completion: 2025-12-01
Conditions
Glioblastoma, IDH-wildtype
Interventions
DRUG
No Results Yet
NCT06355323 | COMPLETED | NA
46 Participants

Bronchiectasis Prevalence in Patients With Primary Humoral Immunodefiency in Champagne-Ardenne Region, France

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-11-28
Completion: 2024-03-11
Conditions
Primary Immunodeficiency Common Variable Immunodeficiency Igg Subclass Deficiency Selective IgM Deficiency
Interventions
OTHER
No Results Yet
NCT06351631 | RECRUITING | PHASE3
400 Participants

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-05-23
Completion: 2034-12-04
Conditions
Thrombocythemia, Essential Primary Myelofibrosis Myelofibrosis Post-polycythemia Vera Myelofibrosis Post-essential Thrombocythemia Myelofibrosis Polycythemia Vera
Interventions
DRUG
No Results Yet
NCT06346873 | WITHDRAWN | NA
0 Participants

Demonstrating Efficacy of JOGO for the Treatment of Tremor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-03
Completion: 2025-01-03
Conditions
Functional Neurological Disorder
Interventions
DEVICE
No Results Yet
NCT06344130 | RECRUITING | PHASE1
28 Participants

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-01
Completion: 2027-12-31
Conditions
Astrocytoma Glioma Recurrent Glioblastoma
Interventions
RADIATION
No Results Yet
NCT06338553 | RECRUITING | EARLY_PHASE1
24 Participants

GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-12
Completion: 2027-03-31
Conditions
Type 1 Diabetes
Interventions
DRUG
No Results Yet
NCT06334107 | RECRUITING | NA
60 Participants

Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-05-01
Completion: 2026-12-01
Conditions
Preterm Birth
Interventions
BEHAVIORAL
No Results Yet
NCT06309355 | COMPLETED | PHASE2
35 Participants

Topical YR001 Ointment in Adult With Mild to Moderate Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-19
Completion: 2025-11-20
Conditions
Atopic Dermatitis
Interventions
DRUG OTHER
No Results Yet
NCT06307652 | RECRUITING | PHASE3
4800 Participants

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-04-12
Completion: 2027-06-11
Conditions
Heart Failure and Impaired Kidney Function
Interventions
DRUG
No Results Yet
NCT06297265 | RECRUITING | NA
50 Participants

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-05-24
Completion: 2026-05-24
Conditions
Anatomic Stage 0 Breast Cancer AJCC v8 Anatomic Stage IA Breast Cancer AJCC v8 Localized Breast Carcinoma
Interventions
OTHER RADIATION
No Results Yet
NCT06296420 | RECRUITING
420 Participants

Dysphagia After Thyroidectomy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-01-31
Completion: 2026-11-30
Conditions
Goiter Thyroid Disease
No Results Yet
NCT06293690 | ACTIVE_NOT_RECRUITING | PHASE2
40 Participants

Toripalimab Combined With SBRT for NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-04-15
Completion: 2025-12-30
Conditions
Non-small Lung Cancer
Interventions
DRUG
No Results Yet
NCT06290934 | ACTIVE_NOT_RECRUITING | PHASE2
228 Participants

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-03-27
Completion: 2026-03-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
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