Clinical Trials Updated in 2025

NCT05850520 | COMPLETED | PHASE3

892 Participants

A Study to Learn How Well a Higher Amount of Aflibercept Given as an Injection Into the Eye Works and How Safe it is in People With Reduced Vision Due to Swelling in the Macula, Central Part of the Retina Caused by a Blocked Vein in the Retina (Macula Edema Secondary to Retinal Vein Occlusion)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-05-15

Completion: 2024-11-07

Conditions

Macular Edema Secondary to Retinal Vein Occlusion

Interventions

DRUG DIAGNOSTIC_TEST

Results Available

NCT05850416 | RECRUITING | NA

75 Participants

mGlide-Care: A Partnership With Caregivers

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-12-15

Completion: 2028-05-30

Conditions

HTN

Interventions

OTHER

No Results Yet

NCT05850364 | COMPLETED | PHASE3

1442 Participants

A Multi-center, Open-labelled, Randomized, Controlled, Extended Phase Ⅲ Clinical Trial of sIPV Vaccine

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-05-22

Completion: 2025-02-13

Conditions

Poliomyelitis Polio

Interventions

BIOLOGICAL

No Results Yet

NCT05842954 | COMPLETED | PHASE3

1720 Participants

Efficacy, Safety and Tolerability of KLU156 in Adults and Children With Uncomplicated P. Falciparum Malaria

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-03-07

Completion: 2025-06-27

Conditions

Uncomplicated Plasmodium Falciparum Malaria

Interventions

DRUG

No Results Yet

NCT05838677 | COMPLETED | NA

380 Participants

Pain at Work Toolkit in Employees With Chronic Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-07-01

Completion: 2025-07-22

Conditions

Chronic Pain Pain, Chronic

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT05837936 | RECRUITING

600 Participants

Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2023-03-28

Completion: 2028-03-31

Conditions

Extubation

Interventions

OTHER

No Results Yet

NCT05836324 | RECRUITING | PHASE1

408 Participants

A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-07-24

Completion: 2027-01-13

Conditions

Solid Tumors Advanced Solid Tumors Metastatic Solid Tumors

Interventions

DRUG

No Results Yet

NCT05834725 | ACTIVE_NOT_RECRUITING | NA

260 Participants

Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-05-08

Completion: 2025-11-02

Conditions

Pain, Chronic Pain Syndrome Psychological

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT05829330 | RECRUITING | NA

46 Participants

Ambulatory Versus Inpatient Initiation of Home Mechanical Ventilation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-09-20

Completion: 2026-02-28

Conditions

Amyotrophic Lateral Sclerosis

Interventions

OTHER

No Results Yet

NCT05822544 | RECRUITING | PHASE1

564 Participants

Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-04-22

Completion: 2026-02-28

Conditions

Healthy Subjects Obesity Type 2 Diabetes

Interventions

DRUG OTHER

No Results Yet

NCT05821413 | COMPLETED | NA

160 Participants

Implementation a Data-to-Care Strategy to Improve HIV Continuum Outcomes for Out of Care People Living With HIV (PLWH) in Ukraine

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-06-16

Completion: 2024-11-13

Conditions

HIV Infections

Interventions

BEHAVIORAL

No Results Yet

NCT05815238 | COMPLETED

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2023-03-10

Completion: 2026-12-31

Conditions

Axial Length Myopia Child Development

No Results Yet

NCT05764161 | COMPLETED | PHASE3

190 Participants

A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-06-12

Completion: 2024-12-30

Conditions

Prurigo Nodularis

Interventions

DRUG

Results Available

NCT05758415 | TERMINATED | PHASE3

60 Participants

Study of Efficacy and Safety of Secukinumab in Participants With Moderate-severe Rotator Cuff Tendinopathy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-08-02

Completion: 2024-10-17

Conditions

Rotator Cuff Tendinopathy

Interventions

DRUG

Results Available

NCT05745883 | ACTIVE_NOT_RECRUITING | PHASE1

50 Participants

Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-04-04

Completion: 2026-01-31

Conditions

Chronic Kidney Diseases Anemia of Chronic Kidney Disease

Interventions

DRUG

No Results Yet

NCT05743673 | RECRUITING

371 Participants

SHAPE Test for Preoperative Risk Stratification

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2023-05-03

Completion: 2026-05-29

Conditions

Perioperative/Postoperative Complications Aerobic Capacity

Interventions

DEVICE

No Results Yet

NCT05742178 | RECRUITING | NA

2160 Participants

NYC Cancer Outreach Network in Neighborhoods for Equity and Community Translation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-07-05

Completion: 2026-10-01

Conditions

Cancer Screening

Interventions

BEHAVIORAL

No Results Yet

NCT05735743 | ACTIVE_NOT_RECRUITING | NA

176 Participants

MoVE Trial: Motivational Strategies to Empower African Americans to Improve Dialysis Adherence

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-10-09

Completion: 2027-11-01

Conditions

End Stage Renal Disease on Dialysis

Interventions

BEHAVIORAL

No Results Yet

NCT05735431 | WITHDRAWN | PHASE3

0 Participants

Non-Inferiority,Combination Formoterol/FluticasonexAlenia®Formoterol/Budesonide for Asthma in Brazil

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2026-06-30

Completion: 2027-11-30

Conditions

Moderate Asthma

Interventions

DRUG

No Results Yet

NCT05721729 | COMPLETED | PHASE2

15 Participants

Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-06-23

Completion: 2024-05-01

Conditions

Postbariatric Hypoglycemia

Interventions

DRUG

No Results Yet

NCT05720039 | ACTIVE_NOT_RECRUITING | NA

204 Participants

Robotic vs. Open NSM for Early Stage Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-05-08

Completion: 2025-12-31

Conditions

Breast Cancer Female Breast Cancer Breast Cancer, Early-Onset Breast Disease Breast

Interventions

DEVICE PROCEDURE

No Results Yet

NCT05718817 | ENROLLING_BY_INVITATION | PHASE3

880 Participants

An Open-label Study of XEN1101 in Epilepsy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-04-25

Completion: 2028-07-31

Conditions

Focal Epilepsy Tonic-Clonic Seizures

Interventions

DRUG

No Results Yet

NCT05697562 | RECRUITING | NA

80 Participants

Evaluation of Superior Rectal Arterial Embolization in Hemorrhoidal Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-06-01

Completion: 2030-12-31

Conditions

Hemorrhoids

Interventions

PROCEDURE

No Results Yet

NCT05695040 | RECRUITING | NA

88 Participants

Evaluation of the Implementation of a Diet Workshop on the 15th Postoperative Day Following Bariatric Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-12-08

Completion: 2028-03-31

Conditions

Bariatric Surgery Candidate

Interventions

BEHAVIORAL

No Results Yet

NCT05688969 | RECRUITING | NA

16 Participants

Mechanisms of Anabolic Osteoporosis Therapy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-06-14

Completion: 2028-02-29

Conditions

Osteoporosis, Postmenopausal

Interventions

OTHER

No Results Yet

NCT05680766 | RECRUITING | NA

30 Participants

Feasibility Assessment of Cardiovascular Endurance Training for the Symptomatic Improvement of Irritable Bowel Syndrome Patients With a Sedentary and Non-active Lifestyle.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-10-16

Completion: 2026-01-02

Conditions

Irritable Bowel Syndrome

Interventions

OTHER

No Results Yet

NCT05663034 | RECRUITING | NA

360 Participants

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-05-10

Completion: 2026-05-31

Conditions

Traumatic Brain Injury Insomnia Depression Post-traumatic Stress Sleep Memory Impairment Cognitive Behavioral Therapy Concussion, Brain Head Injury Brain Injury Traumatic Mild

Interventions

BEHAVIORAL

No Results Yet

NCT05653349 | ACTIVE_NOT_RECRUITING | PHASE3

226 Participants

Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-02-03

Completion: 2026-04-24

Conditions

Primary Immune Thrombocytopenia (ITP)

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT05640336 | ENROLLING_BY_INVITATION | NA

490 Participants

Treatment of Acute Periprosthetic Joint Infection Comparing Single and Planned Double-Debridement Antibiotics and Implant Retention Followed by Chronic Antibiotic Suppression

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-03-03

Completion: 2032-03-31

Conditions

Periprosthetic Joint Infection

Interventions

PROCEDURE

No Results Yet

NCT05637710 | WITHDRAWN | PHASE3

0 Participants

Parallel, Double-dummy, Superiority Study Levocetirizine/Pseudoephedrine x Zina for Allergic Rhinitis in Brazil

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2026-03-31

Completion: 2027-05-31

Conditions

Allergic Rhinitis

Interventions

DRUG

No Results Yet

NCT05636501 | ACTIVE_NOT_RECRUITING | NA

120 Participants

Treat-to-target Prednisolon Taper in Patients With Polymyalgia Rheumatica

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-01-12

Completion: 2025-10-09

Conditions

Polymyalgia Rheumatica

Interventions

OTHER

No Results Yet

NCT05624268 | ACTIVE_NOT_RECRUITING | PHASE3

255 Participants

Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-01-19

Completion: 2025-05-28

Conditions

Treatment Resistant Depression

Interventions

DRUG

No Results Yet

NCT05622708 | ACTIVE_NOT_RECRUITING | PHASE4

241 Participants

A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-03-28

Completion: 2028-04-19

Conditions

Non-radiographic Axial Spondyloarthritis

Interventions

DRUG

No Results Yet