Robotic vs. Open NSM for Early Stage Breast Cancer

NCT ID: NCT05720039

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

204 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-08

Study Completion Date

2030-12-31

Brief Summary

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This study evaluates the safety and effectiveness of the da Vinci SP Surgical System compared to Open NSM in Nipple Sparing Mastectomy procedures.

Detailed Description

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This study is a prospective, two-arm, multi-center, randomized controlled clinical investigation between RSNM and open NSM.

This study evaluates the safety and effectiveness of the da Vinci SP Surgical System compared to Open NSM in Nipple Sparing Mastectomy procedures.

Conditions

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Breast Cancer Female Breast Cancer Breast Cancer, Early-Onset Breast Disease Breast

Keywords

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robotic NSM Nipple sparing mastectomy da Vinci breast cancer mastectomy breast USA robot SP System Single-port

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Subjects undergo nipple-sparing mastectomy (NSM) procedures using the da Vinci SP Surgical System or open NSM
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Robotic NSM with da Vinci SP

Subjects randomized to this arm will undergo robotic NSM (RNSM) procedures

Group Type EXPERIMENTAL

Robotic NSM

Intervention Type DEVICE

Robotic-assisted Nipple sparing mastectomy procedures

Open NSM

Subjects randomized to this arm will undergo conventional open NSM procedures

Group Type ACTIVE_COMPARATOR

Open NSM

Intervention Type PROCEDURE

open nipple-sparing mastectomy procedures

Interventions

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Robotic NSM

Robotic-assisted Nipple sparing mastectomy procedures

Intervention Type DEVICE

Open NSM

open nipple-sparing mastectomy procedures

Intervention Type PROCEDURE

Other Intervention Names

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RNSM SP NSM

Eligibility Criteria

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Inclusion Criteria

* Female age 21 or older
* BMI \< 30
* Candidate for an NSM procedure with immediate reconstruction
* Diagnosis of early stage brest cancer
* Breast ptosis ≤ Grade 2.
* Cup size ≤ C.

Exclusion Criteria

* Previous breast surgery
* Diagnosis of metastatic breast cancer
* Prior radiation treatment to the chest
* Current smokers
* Contraindication for general anesthesia or surgery.
* Known bleeding or clotting disorder.
* Pregnant or suspected to be pregnant, or actively breastfeeding
Minimum Eligible Age

21 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Intuitive Surgical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Madhu Gorrepati

Role: STUDY_DIRECTOR

Intuitive

Locations

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City of Hope

Irvine, California, United States

Site Status

Cedars-Sinai

Los Angeles, California, United States

Site Status

Mayo Clinic Florida

Jacksonville, Florida, United States

Site Status

Emory University

Atlanta, Georgia, United States

Site Status

Endeavor Health

Evanston, Illinois, United States

Site Status

Corewell

Detroit, Michigan, United States

Site Status

Mayo Clinic Rochester

Rochester, Minnesota, United States

Site Status

Washington University, St. Louis

St Louis, Missouri, United States

Site Status

Northwell Health

Lake Success, New York, United States

Site Status

Duke University

Durham, North Carolina, United States

Site Status

University of Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status

Vanderbilt

Nashville, Tennessee, United States

Site Status

MD Anderson Cancer Center

Houston, Texas, United States

Site Status

University of Washington

Seattle, Washington, United States

Site Status

Ascension St. Columbia Mary's

Milwaukee, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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ISI dV SP - NSM-01

Identifier Type: -

Identifier Source: org_study_id