Clinical Trials

Showing trials with last updates posted in 2025.

NCT05821413 | COMPLETED | NA
160 Participants

Implementation a Data-to-Care Strategy to Improve HIV Continuum Outcomes for Out of Care People Living With HIV (PLWH) in Ukraine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-06-16
Completion: 2024-11-13
Conditions
HIV Infections
Interventions
BEHAVIORAL
No Results Yet
NCT05815238 | COMPLETED
60 Participants

Changes in Foot Posture With Age: Functional and Balance Effects

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2025-03-01
Completion: 2025-03-01
Conditions
Foot Posture Index Score
No Results Yet
NCT05810948 | COMPLETED | PHASE2
73 Participants

A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-02-21
Completion: 2025-07-02
Conditions
Lupus Nephritis
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05805774 | RECRUITING | NA
148 Participants

pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-10-17
Completion: 2030-12-10
Conditions
Distal Femur Fracture Periprosthetic Fracture Around Prosthetic Joint Implant Knee Knee Fracture
Interventions
PROCEDURE
No Results Yet
NCT05801939 | ACTIVE_NOT_RECRUITING | PHASE2
30 Participants

Cevostamab Following CAR T Cell Therapy for RRMM

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-07-11
Completion: 2027-05-31
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05791864 | RECRUITING | PHASE1/PHASE2
16 Participants

A First-in-Human, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Gene Therapy With TTX-381 for the Ocular Manifestations Associated With Neuronal Ceroid Lipofuscinosis Type 2 (CLN2) Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-05-17
Completion: 2026-07-30
Conditions
Neuronal Ceroid Lipofuscinosis Type 2
Interventions
GENETIC
No Results Yet
NCT05782543 | RECRUITING | NA
240 Participants

Renal Ex Vivo Warm Advanced Resuscitation Through Machine Perfusion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-15
Completion: 2027-12-01
Conditions
Kidney Transplant; Complications
Interventions
PROCEDURE
No Results Yet
NCT05770947 | COMPLETED | NA
25 Participants

Cognitive Behavioral Therapy for Adolescents With Bulimia Nervosa and Higher Weight (Online Treatment Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-01-24
Completion: 2025-06-27
Conditions
Bulimia Nervosa Overweight or Obesity
Interventions
BEHAVIORAL
No Results Yet
NCT05770661 | RECRUITING
30000 Participants

China Axial Length Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2023-03-10
Completion: 2026-12-31
Conditions
Axial Length Myopia Child Development
No Results Yet
NCT05764161 | COMPLETED | PHASE3
190 Participants

A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-06-12
Completion: 2024-12-30
Conditions
Prurigo Nodularis
Interventions
DRUG
NCT05758415 | TERMINATED | PHASE3
60 Participants

Study of Efficacy and Safety of Secukinumab in Participants With Moderate-severe Rotator Cuff Tendinopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-08-02
Completion: 2024-10-17
Conditions
Rotator Cuff Tendinopathy
Interventions
DRUG
NCT05745883 | ACTIVE_NOT_RECRUITING | PHASE1
50 Participants

Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-04-04
Completion: 2026-01-31
Conditions
Chronic Kidney Diseases Anemia of Chronic Kidney Disease
Interventions
DRUG
No Results Yet
NCT05743673 | RECRUITING
371 Participants

SHAPE Test for Preoperative Risk Stratification

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2023-05-03
Completion: 2026-05-29
Conditions
Perioperative/Postoperative Complications Aerobic Capacity
Interventions
DEVICE
No Results Yet
NCT05742178 | RECRUITING | NA
2160 Participants

NYC Cancer Outreach Network in Neighborhoods for Equity and Community Translation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-07-05
Completion: 2026-10-01
Conditions
Cancer Screening
Interventions
BEHAVIORAL
No Results Yet
NCT05735743 | ACTIVE_NOT_RECRUITING | NA
176 Participants

MoVE Trial: Motivational Strategies to Empower African Americans to Improve Dialysis Adherence

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-10-09
Completion: 2027-11-01
Conditions
End Stage Renal Disease on Dialysis
Interventions
BEHAVIORAL
No Results Yet
NCT05735431 | WITHDRAWN | PHASE3
0 Participants

Non-Inferiority,Combination Formoterol/FluticasonexAlenia®Formoterol/Budesonide for Asthma in Brazil

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-06-30
Completion: 2027-11-30
Conditions
Moderate Asthma
Interventions
DRUG
No Results Yet
NCT05721729 | COMPLETED | PHASE2
15 Participants

Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-06-23
Completion: 2024-05-01
Conditions
Postbariatric Hypoglycemia
Interventions
DRUG
No Results Yet
NCT05720039 | ACTIVE_NOT_RECRUITING | NA
204 Participants

Robotic vs. Open NSM for Early Stage Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-05-08
Completion: 2025-12-31
Conditions
Breast Cancer Female Breast Cancer Breast Cancer, Early-Onset Breast Disease Breast
Interventions
DEVICE PROCEDURE
No Results Yet
NCT05718817 | ENROLLING_BY_INVITATION | PHASE3
880 Participants

An Open-label Study of XEN1101 in Epilepsy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-04-25
Completion: 2028-07-31
Conditions
Focal Epilepsy Tonic-Clonic Seizures
Interventions
DRUG
No Results Yet
NCT05697562 | RECRUITING | NA
80 Participants

Evaluation of Superior Rectal Arterial Embolization in Hemorrhoidal Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-06-01
Completion: 2030-12-31
Conditions
Hemorrhoids
Interventions
PROCEDURE
No Results Yet
NCT05695040 | RECRUITING | NA
88 Participants

Evaluation of the Implementation of a Diet Workshop on the 15th Postoperative Day Following Bariatric Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-12-08
Completion: 2028-03-31
Conditions
Bariatric Surgery Candidate
Interventions
BEHAVIORAL
No Results Yet
NCT05688969 | RECRUITING | NA
16 Participants

Mechanisms of Anabolic Osteoporosis Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-06-14
Completion: 2028-02-29
Conditions
Osteoporosis, Postmenopausal
Interventions
OTHER
No Results Yet
NCT05680766 | RECRUITING | NA
30 Participants

Feasibility Assessment of Cardiovascular Endurance Training for the Symptomatic Improvement of Irritable Bowel Syndrome Patients With a Sedentary and Non-active Lifestyle.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-10-16
Completion: 2026-01-02
Conditions
Irritable Bowel Syndrome
Interventions
OTHER
No Results Yet
NCT05663034 | RECRUITING | NA
360 Participants

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-05-10
Completion: 2026-05-31
Conditions
Traumatic Brain Injury Insomnia Depression Post-traumatic Stress Sleep Memory Impairment Cognitive Behavioral Therapy Concussion, Brain Head Injury Brain Injury Traumatic Mild
Interventions
BEHAVIORAL
No Results Yet
NCT05653349 | ACTIVE_NOT_RECRUITING | PHASE3
226 Participants

Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-02-03
Completion: 2026-04-24
Conditions
Primary Immune Thrombocytopenia (ITP)
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05640336 | ENROLLING_BY_INVITATION | NA
490 Participants

Treatment of Acute Periprosthetic Joint Infection Comparing Single and Planned Double-Debridement Antibiotics and Implant Retention Followed by Chronic Antibiotic Suppression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-03-03
Completion: 2032-03-31
Conditions
Periprosthetic Joint Infection
Interventions
PROCEDURE
No Results Yet
NCT05637710 | WITHDRAWN | PHASE3
0 Participants

Parallel, Double-dummy, Superiority Study Levocetirizine/Pseudoephedrine x Zina for Allergic Rhinitis in Brazil

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-03-31
Completion: 2027-05-31
Conditions
Allergic Rhinitis
Interventions
DRUG
No Results Yet
NCT05636501 | ACTIVE_NOT_RECRUITING | NA
120 Participants

Treat-to-target Prednisolon Taper in Patients With Polymyalgia Rheumatica

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-01-12
Completion: 2025-10-09
Conditions
Polymyalgia Rheumatica
Interventions
OTHER
No Results Yet
NCT05624268 | ACTIVE_NOT_RECRUITING | PHASE3
255 Participants

Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-01-19
Completion: 2025-05-28
Conditions
Treatment Resistant Depression
Interventions
DRUG
No Results Yet
NCT05622708 | ACTIVE_NOT_RECRUITING | PHASE4
241 Participants

A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-03-28
Completion: 2028-04-19
Conditions
Non-radiographic Axial Spondyloarthritis
Interventions
DRUG
No Results Yet
NCT05621044 | ACTIVE_NOT_RECRUITING | NA
36 Participants

Physical Activity Smartphone App for African American Men (FitBros) Ph II

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-05-01
Completion: 2025-12-01
Conditions
Exercise Health Behavior Technology
Interventions
BEHAVIORAL
No Results Yet
NCT05619211 | COMPLETED | PHASE1
42 Participants

Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-09-29
Completion: 2025-11-01
Conditions
Cerebral Palsy
Interventions
BEHAVIORAL
No Results Yet
NCT05603832 | COMPLETED | PHASE3
151 Participants

A Phase 3 Study of F14 for Management of Pain Following Total Knee Replacement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-11-17
Completion: 2023-11-22
Conditions
Post Operative Pain
Interventions
DRUG
No Results Yet
NCT05599724 | TERMINATED
250 Participants

PMA-FERTITHEQUE Biocollection

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2022-11-11
Completion: 2023-04-24
Conditions
Infertility Infertility Unexplained
Interventions
OTHER
No Results Yet
NCT05593666 | ACTIVE_NOT_RECRUITING | PHASE2
101 Participants

A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral Leishmaniasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-12-27
Completion: 2025-04-15
Conditions
Primary Visceral Leishmaniasis
Interventions
DRUG OTHER
No Results Yet
NCT05583604 | AVAILABLE

Managed Access Programs for AIN457, Secukinumab

Study Type: EXPANDED_ACCESS
Last Updated: 2025-12-18
Conditions
Hidradenitis Suppurativa (HS)
Interventions
DRUG
No Results Yet
NCT05574439 | RECRUITING | PHASE4
180 Participants

Young Adults With Early-onset Obesity Treated With Semaglutide

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-06-01
Completion: 2026-04-30
Conditions
Obesity, Adolescent
Interventions
BEHAVIORAL DRUG
No Results Yet
NCT05565716 | COMPLETED | NA
70 Participants

Supporting Self-Management of Healthy Behaviors in Diabetes, Kidney Disease, and Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2023-08-21
Completion: 2025-01-31
Conditions
Renal Insufficiency, Chronic Hypertension Diabetes
Interventions
OTHER
No Results Yet
NCT05555082 | COMPLETED | NA
25 Participants

Can Massage During One Year Improve Health in Health-care Providers Working in Hospital

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2022-11-20
Completion: 2024-03-01
Conditions
Massage Therapy Health-care Workers Quality of Life Psychological Distress
Interventions
OTHER
NCT05550675 | RECRUITING
150 Participants

Prospective Database of Factors Associated With Faecal vs. Double Incontinence in Patients Referred for High Resolution Anorectal Manometry.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2022-06-08
Completion: 2027-07-31
Conditions
Double Incontinence Faecal Incontinence Urinary Incontinence
Interventions
OTHER
No Results Yet
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