Clinical Trials
Showing trials with last updates posted in 2025.
700
Participants
Genetics of Response to Canagliflozin
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2016-09-30
Completion:
2023-09-25
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
64
Participants
Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2018-02-02
Completion:
2026-03-31
Conditions
Untreated Adult Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
614
Participants
Duration of Anti-PD-1 Therapy in Metastatic Melanoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2016-10-31
Completion:
2027-12-31
Conditions
Unresectable/Metastatic Melanoma
Interventions
DRUG
No Results Yet
3
Participants
PEmbrolizumab Combined With Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2017-07-12
Completion:
2019-11-28
Conditions
Squamous Cell Carcinoma of the Head and Neck
Squamous Cell Carcinoma
Interventions
DRUG
RADIATION
160
Participants
A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2015-01-01
Completion:
2030-01-31
Conditions
Renal Artery Obstruction
Hypertension, Renovascular
Cardiovascular Diseases
Kidney Diseases
Interventions
DEVICE
No Results Yet
18
Participants
Matched Paired Pharmacodynamics and Feasibility Study of Durvalumab in Combination With Chemotherapy in Frontline Ovarian Cancer (N-Dur)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2016-07-06
Completion:
2027-12-31
Conditions
Stage III Fallopian Tube Cancer AJCC v7
Stage III Ovarian Cancer AJCC v6 and v7
Stage III Primary Peritoneal Cancer AJCC v7
Stage IIIA Fallopian Tube Cancer AJCC v7
Stage IIIA Ovarian Cancer AJCC v6 and v7
Stage IIIA Primary Peritoneal Cancer AJCC v7
Stage IIIB Fallopian Tube Cancer AJCC v7
Stage IIIB Ovarian Cancer AJCC v6 and v7
Stage IIIB Primary Peritoneal Cancer AJCC v7
Stage IIIC Fallopian Tube Cancer AJCC v7
Stage IIIC Ovarian Cancer AJCC v6 and v7
Stage IIIC Primary Peritoneal Cancer AJCC v7
Stage IV Fallopian Tube Cancer AJCC v6 and v7
Stage IV Ovarian Cancer AJCC v6 and v7
Stage IV Primary Peritoneal Cancer AJCC v7
Interventions
DRUG
BIOLOGICAL
OTHER
No Results Yet
200
Participants
An Integrated Consent Model Study to Compare Two Standard of Care Schedules for Monitoring Cardiac Function in Patients Receiving Trastuzumab for Early Stage Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2016-06-30
Completion:
2020-05-31
Conditions
Breast Cancer
Interventions
PROCEDURE
4400
Participants
Blue Light Cystoscopy With Cysview® Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2014-04-30
Completion:
2028-12-31
Conditions
Bladder Cancer
Interventions
DRUG
DEVICE
No Results Yet
34
Participants
Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2016-03-04
Completion:
2021-10-16
Conditions
Malignant Pleural Mesothelioma
Mesothelioma
Interventions
DRUG
OTHER
38
Participants
A Phase I Study to Assess Ebola Vaccines cAd3-EBO Z and MVA-EBO Z
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2015-05-06
Completion:
2017-08-22
Conditions
Ebola Virus Disease
Interventions
BIOLOGICAL
No Results Yet
1571
Participants
Registry of Patients With Hypophosphatasia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2015-01-20
Completion:
2031-12-31
Conditions
Hypophosphatasia (HPP)
No Results Yet
60
Participants
Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2014-07-08
Completion:
2026-06-30
Conditions
Glioblastoma Multiforme
Interventions
DRUG
RADIATION
No Results Yet
608
Participants
Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2014-03-29
Completion:
2020-05-05
Conditions
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Breast Adenocarcinoma
HER2/Neu Negative
Locally Advanced Breast Carcinoma
Metastatic Breast Carcinoma
Recurrent Breast Carcinoma
Interventions
PROCEDURE
DRUG
OTHER
1685
Participants
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2014-08-05
Completion:
2029-08-05
Conditions
Genetic Eye Disease
No Results Yet
33
Participants
REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2013-09-30
Completion:
2025-06-03
Conditions
Estrogen Receptor Positive Breast Cancer
Breast Cancer
Interventions
DRUG
No Results Yet
15
Participants
MIBG for Refractory Neuroblastoma and Pheochromocytoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2013-12-31
Completion:
2025-10-20
Conditions
Relapsed Neuroblastoma
Metastatic Pheochromocytoma
Interventions
DRUG
PROCEDURE
No Results Yet
550
Participants
Prospective Data Bank Creation to Study Vaginal Conditions
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2013-04-30
Completion:
2027-07-31
Conditions
Vulvodynia
Mycoses
Bacterial Vaginosis
Preterm Labor
No Results Yet
40
Participants
Myocardial Inflammation in Systemic Lupus Erythematosus
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2012-07-01
Completion:
2026-11-01
Conditions
SLE
No Results Yet
25875
Participants
Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2011-11-30
Completion:
2025-11-30
Conditions
Hypertension
Interventions
DIETARY_SUPPLEMENT
DRUG
No Results Yet
8000
Participants
European Multicentre Study of Human Spinal Cord Injury
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2004-04-30
Completion:
2026-08-31
Conditions
Spinal Cord Injury
No Results Yet
314
Participants
Communication Skills Intervention to Promote Transition Into Survivorship
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2011-11-30
Completion:
2026-11-30
Conditions
Hodgkin's Lymphoma
Diffuse Large B-cell Lymphoma
No Results Yet
250
Participants
Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2011-10-20
Completion:
2026-04-30
Conditions
Lymphatic Diseases
Hematopoietic Malignancy
Interventions
BIOLOGICAL
No Results Yet
276
Participants
Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2011-08-26
Completion:
2027-12-25
Conditions
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Burkitt-Like Lymphoma With 11q Aberration
High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements
High Grade B-Cell Lymphoma, Not Otherwise Specified
Recurrent B Acute Lymphoblastic Leukemia
Recurrent Burkitt Lymphoma
Refractory B Acute Lymphoblastic Leukemia
Refractory Burkitt Lymphoma
Interventions
BIOLOGICAL
DRUG
OTHER
No Results Yet
20
Participants
Observation of the Gait Cycle in Patients With Hemiplegia in Order to Improve the Triggering of Functional Electrical Stimulation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2011-05-31
Completion:
2013-07-31
Conditions
Stroke
Interventions
OTHER
No Results Yet
100
Participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2002-08-31
Completion:
2099-01-31
Conditions
Stomach Cancer
Gastro-Esophageal(GE) Junction Cancer
Gastric (Stomach) Cancer
Esophageal Cancer
Gastrointestinal Stromal Tumor (GIST)
Interventions
PROCEDURE
No Results Yet
33
Participants
Clinical and Cost Effectiveness of ACE Inhibitor, Ramipril, in Intermittent Claudicants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2010-12-31
Completion:
2012-12-31
Conditions
Intermittent Claudicants
Interventions
DRUG
1000
Participants
Establishment of Cell Culture Systems From Discarded Operating Room Tissue
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2009-02-28
Completion:
2035-12-31
Conditions
Surgery
No Results Yet
45
Participants
Abundance and Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease (NAFLD)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2009-10-31
Completion:
2026-11-30
Conditions
Nonalcoholic Fatty Liver Disease
No Results Yet
9999
Participants
International Pediatric Adrenocortical Tumor Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2001-10-01
Completion:
2040-12-31
Conditions
Adrenocortical Tumor
No Results Yet
30
Participants
Weaning Children From Mechanical Ventilation:Computer-driven System Versus Usual Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2007-09-30
Completion:
2009-06-30
Conditions
Respiratory Failure
Interventions
DEVICE
No Results Yet
22
Participants
Exploratory Study to Assess the Short Term Effect on Liver Enzymes and the Safety of TRO19622 in Patients With Non-Alcoholic Steatohepatitis (NASH)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2008-04-15
Completion:
2009-02-05
Conditions
Non-Alcoholic Steatohepatitis (NASH)
Interventions
DRUG
No Results Yet
2500
Participants
Optical Sensor for Photodynamic Detection of Oral Pathology
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2003-04-30
Completion:
2025-06-03
Conditions
Mouth Diseases
Interventions
DEVICE
No Results Yet
9999
Participants
Bone Marrow Grafting for Leukemia and Lymphoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
1988-03-31
Completion:
2069-12-31
Conditions
Leukemia
Lymphoma
Hematologic Diseases
Interventions
PROCEDURE
No Results Yet
57
Participants
Extension Study Investigating the Long-Term Safety of Degarelix One-Month Depots in Patients With Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2005-03-31
Completion:
2009-09-30
Conditions
Prostate Cancer
Interventions
DRUG
1000
Participants
Collection of Blood and Urine From Patients Undergoing Radiation Therapy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2001-12-02
Conditions
Carcinoma
Cancer
Tumor
No Results Yet
500
Participants
Evaluation and Long-Term Follow-up of Patients With Inflammatory Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
1993-06-01
Conditions
Inflammation
No Results Yet
101
Participants
The Relationship Between Olfactory and Gustatory Senses, Hedonic Hunger, and Diet Quality After Bariatric Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2024-01-01
Completion:
2024-11-30
Conditions
Obesity
Taste Disorders
Smell Disorder
Interventions
OTHER
No Results Yet
23
Participants
A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-31
Completion:
2030-03-31
Conditions
Amyotrophic Lateral Sclerosis
Interventions
GENETIC
No Results Yet
46
Participants
Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-04-24
Completion:
2025-12-25
Conditions
Symptomatic Irreversible Pulpitis
Symptomatic Irreversible Pulpitis (SIP)
Interventions
DEVICE
No Results Yet
126
Participants
Oral and Gut Microbiota in Individuals With Serrated Polyposis Syndrome.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2021-01-11
Completion:
2023-12-31
Conditions
Colorectal Cancer
Serrated Polyposis Syndrome
Intestinal Microbiota
No Results Yet
Showing 40 trials per page