Clinical Trials

Showing trials with last updates posted in 2025.

NCT02891954 | ACTIVE_NOT_RECRUITING | PHASE1
700 Participants

Genetics of Response to Canagliflozin

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-09-30
Completion: 2023-09-25
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT02835222 | RECRUITING | PHASE2
64 Participants

Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-02-02
Completion: 2026-03-31
Conditions
Untreated Adult Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT02821013 | RECRUITING | PHASE3
614 Participants

Duration of Anti-PD-1 Therapy in Metastatic Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-10-31
Completion: 2027-12-31
Conditions
Unresectable/Metastatic Melanoma
Interventions
DRUG
No Results Yet
NCT02819752 | TERMINATED | PHASE1
3 Participants

PEmbrolizumab Combined With Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-07-12
Completion: 2019-11-28
Conditions
Squamous Cell Carcinoma of the Head and Neck Squamous Cell Carcinoma
Interventions
DRUG RADIATION
NCT02770066 | RECRUITING
160 Participants

A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2015-01-01
Completion: 2030-01-31
Conditions
Renal Artery Obstruction Hypertension, Renovascular Cardiovascular Diseases Kidney Diseases
Interventions
DEVICE
No Results Yet
NCT02726997 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
18 Participants

Matched Paired Pharmacodynamics and Feasibility Study of Durvalumab in Combination With Chemotherapy in Frontline Ovarian Cancer (N-Dur)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-07-06
Completion: 2027-12-31
Conditions
Stage III Fallopian Tube Cancer AJCC v7 Stage III Ovarian Cancer AJCC v6 and v7 Stage III Primary Peritoneal Cancer AJCC v7 Stage IIIA Fallopian Tube Cancer AJCC v7 Stage IIIA Ovarian Cancer AJCC v6 and v7 Stage IIIA Primary Peritoneal Cancer AJCC v7 Stage IIIB Fallopian Tube Cancer AJCC v7 Stage IIIB Ovarian Cancer AJCC v6 and v7 Stage IIIB Primary Peritoneal Cancer AJCC v7 Stage IIIC Fallopian Tube Cancer AJCC v7 Stage IIIC Ovarian Cancer AJCC v6 and v7 Stage IIIC Primary Peritoneal Cancer AJCC v7 Stage IV Fallopian Tube Cancer AJCC v6 and v7 Stage IV Ovarian Cancer AJCC v6 and v7 Stage IV Primary Peritoneal Cancer AJCC v7
Interventions
DRUG BIOLOGICAL OTHER
No Results Yet
NCT02696707 | COMPLETED | PHASE4
200 Participants

An Integrated Consent Model Study to Compare Two Standard of Care Schedules for Monitoring Cardiac Function in Patients Receiving Trastuzumab for Early Stage Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-06-30
Completion: 2020-05-31
Conditions
Breast Cancer
Interventions
PROCEDURE
NCT02660645 | RECRUITING
4400 Participants

Blue Light Cystoscopy With Cysview® Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2014-04-30
Completion: 2028-12-31
Conditions
Bladder Cancer
Interventions
DRUG DEVICE
No Results Yet
NCT02611037 | COMPLETED | PHASE2
34 Participants

Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-03-04
Completion: 2021-10-16
Conditions
Malignant Pleural Mesothelioma Mesothelioma
Interventions
DRUG OTHER
NCT02451891 | TERMINATED | PHASE1
38 Participants

A Phase I Study to Assess Ebola Vaccines cAd3-EBO Z and MVA-EBO Z

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2015-05-06
Completion: 2017-08-22
Conditions
Ebola Virus Disease
Interventions
BIOLOGICAL
No Results Yet
NCT02306720 | ENROLLING_BY_INVITATION
1571 Participants

Registry of Patients With Hypophosphatasia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2015-01-20
Completion: 2031-12-31
Conditions
Hypophosphatasia (HPP)
No Results Yet
NCT02177578 | ACTIVE_NOT_RECRUITING | PHASE2
60 Participants

Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2014-07-08
Completion: 2026-06-30
Conditions
Glioblastoma Multiforme
Interventions
DRUG RADIATION
No Results Yet
NCT02115282 | ACTIVE_NOT_RECRUITING | PHASE3
608 Participants

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2014-03-29
Completion: 2020-05-05
Conditions
Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 Breast Adenocarcinoma HER2/Neu Negative Locally Advanced Breast Carcinoma Metastatic Breast Carcinoma Recurrent Breast Carcinoma
Interventions
PROCEDURE DRUG OTHER
NCT02077894 | RECRUITING
1685 Participants

Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2014-08-05
Completion: 2029-08-05
Conditions
Genetic Eye Disease
No Results Yet
NCT01984138 | ACTIVE_NOT_RECRUITING | PHASE2
33 Participants

REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2013-09-30
Completion: 2025-06-03
Conditions
Estrogen Receptor Positive Breast Cancer Breast Cancer
Interventions
DRUG
No Results Yet
NCT01850888 | COMPLETED | NA
15 Participants

MIBG for Refractory Neuroblastoma and Pheochromocytoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2013-12-31
Completion: 2025-10-20
Conditions
Relapsed Neuroblastoma Metastatic Pheochromocytoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT01829204 | RECRUITING
550 Participants

Prospective Data Bank Creation to Study Vaginal Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2013-04-30
Completion: 2027-07-31
Conditions
Vulvodynia Mycoses Bacterial Vaginosis Preterm Labor
No Results Yet
NCT01761422 | ACTIVE_NOT_RECRUITING
40 Participants

Myocardial Inflammation in Systemic Lupus Erythematosus

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2012-07-01
Completion: 2026-11-01
Conditions
SLE
No Results Yet
NCT01653678 | ACTIVE_NOT_RECRUITING | NA
25875 Participants

Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2011-11-30
Completion: 2025-11-30
Conditions
Hypertension
Interventions
DIETARY_SUPPLEMENT DRUG
No Results Yet
NCT01571531 | RECRUITING
8000 Participants

European Multicentre Study of Human Spinal Cord Injury

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2004-04-30
Completion: 2026-08-31
Conditions
Spinal Cord Injury
No Results Yet
NCT01483664 | ACTIVE_NOT_RECRUITING
314 Participants

Communication Skills Intervention to Promote Transition Into Survivorship

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2011-11-30
Completion: 2026-11-30
Conditions
Hodgkin's Lymphoma Diffuse Large B-cell Lymphoma
No Results Yet
NCT01451502 | RECRUITING | NA
250 Participants

Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2011-10-20
Completion: 2026-04-30
Conditions
Lymphatic Diseases Hematopoietic Malignancy
Interventions
BIOLOGICAL
No Results Yet
NCT01371630 | RECRUITING | PHASE1/PHASE2
276 Participants

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2011-08-26
Completion: 2027-12-25
Conditions
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative Burkitt-Like Lymphoma With 11q Aberration High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements High Grade B-Cell Lymphoma, Not Otherwise Specified Recurrent B Acute Lymphoblastic Leukemia Recurrent Burkitt Lymphoma Refractory B Acute Lymphoblastic Leukemia Refractory Burkitt Lymphoma
Interventions
BIOLOGICAL DRUG OTHER
No Results Yet
NCT01257646 | COMPLETED | NA
20 Participants

Observation of the Gait Cycle in Patients With Hemiplegia in Order to Improve the Triggering of Functional Electrical Stimulation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2011-05-31
Completion: 2013-07-31
Conditions
Stroke
Interventions
OTHER
No Results Yet
NCT01048281 | RECRUITING
100 Participants

Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2002-08-31
Completion: 2099-01-31
Conditions
Stomach Cancer Gastro-Esophageal(GE) Junction Cancer Gastric (Stomach) Cancer Esophageal Cancer Gastrointestinal Stromal Tumor (GIST)
Interventions
PROCEDURE
No Results Yet
NCT01037530 | COMPLETED | PHASE4
33 Participants

Clinical and Cost Effectiveness of ACE Inhibitor, Ramipril, in Intermittent Claudicants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2010-12-31
Completion: 2012-12-31
Conditions
Intermittent Claudicants
Interventions
DRUG
NCT01000077 | ENROLLING_BY_INVITATION
1000 Participants

Establishment of Cell Culture Systems From Discarded Operating Room Tissue

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2009-02-28
Completion: 2035-12-31
Conditions
Surgery
No Results Yet
NCT00983463 | ENROLLING_BY_INVITATION
45 Participants

Abundance and Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease (NAFLD)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2009-10-31
Completion: 2026-11-30
Conditions
Nonalcoholic Fatty Liver Disease
No Results Yet
NCT00700414 | RECRUITING
9999 Participants

International Pediatric Adrenocortical Tumor Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2001-10-01
Completion: 2040-12-31
Conditions
Adrenocortical Tumor
No Results Yet
NCT00678912 | COMPLETED | NA
30 Participants

Weaning Children From Mechanical Ventilation:Computer-driven System Versus Usual Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2007-09-30
Completion: 2009-06-30
Conditions
Respiratory Failure
Interventions
DEVICE
No Results Yet
NCT00666016 | COMPLETED | PHASE2
22 Participants

Exploratory Study to Assess the Short Term Effect on Liver Enzymes and the Safety of TRO19622 in Patients With Non-Alcoholic Steatohepatitis (NASH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2008-04-15
Completion: 2009-02-05
Conditions
Non-Alcoholic Steatohepatitis (NASH)
Interventions
DRUG
No Results Yet
NCT00540774 | SUSPENDED | NA
2500 Participants

Optical Sensor for Photodynamic Detection of Oral Pathology

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2003-04-30
Completion: 2025-06-03
Conditions
Mouth Diseases
Interventions
DEVICE
No Results Yet
NCT00186147 | ENROLLING_BY_INVITATION
9999 Participants

Bone Marrow Grafting for Leukemia and Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 1988-03-31
Completion: 2069-12-31
Conditions
Leukemia Lymphoma Hematologic Diseases
Interventions
PROCEDURE
No Results Yet
NCT00117286 | COMPLETED | PHASE2/PHASE3
57 Participants

Extension Study Investigating the Long-Term Safety of Degarelix One-Month Depots in Patients With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2005-03-31
Completion: 2009-09-30
Conditions
Prostate Cancer
Interventions
DRUG
NCT00027326 | ENROLLING_BY_INVITATION
1000 Participants

Collection of Blood and Urine From Patients Undergoing Radiation Therapy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2001-12-02
Conditions
Carcinoma Cancer Tumor
No Results Yet
NCT00001351 | ENROLLING_BY_INVITATION
500 Participants

Evaluation and Long-Term Follow-up of Patients With Inflammatory Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 1993-06-01
Conditions
Inflammation
No Results Yet
NCT07290075 | COMPLETED
101 Participants

The Relationship Between Olfactory and Gustatory Senses, Hedonic Hunger, and Diet Quality After Bariatric Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2024-01-01
Completion: 2024-11-30
Conditions
Obesity Taste Disorders Smell Disorder
Interventions
OTHER
No Results Yet
NCT07290062 | NOT_YET_RECRUITING | PHASE1
23 Participants

A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-31
Completion: 2030-03-31
Conditions
Amyotrophic Lateral Sclerosis
Interventions
GENETIC
No Results Yet
NCT07290049 | RECRUITING | NA
46 Participants

Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-04-24
Completion: 2025-12-25
Conditions
Symptomatic Irreversible Pulpitis Symptomatic Irreversible Pulpitis (SIP)
Interventions
DEVICE
No Results Yet
NCT07290023 | COMPLETED
126 Participants

Oral and Gut Microbiota in Individuals With Serrated Polyposis Syndrome.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2021-01-11
Completion: 2023-12-31
Conditions
Colorectal Cancer Serrated Polyposis Syndrome Intestinal Microbiota
No Results Yet
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