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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07056348 | RECRUITING | NA
60 Participants

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2022-05-10
Completion: 2030-12-31
Conditions
Traumatic Brain Injury Stroke Brain Disease Movement Disorders (Incl Parkinsonism) Central Nervous System Disease Essential Tremor, Movement Disorders Essential Tremor of Voice
Interventions
DEVICE
No Results Yet
NCT07052838 | RECRUITING | PHASE3
32 Participants

Efficacy and Safety of HSK39297 in Anti-C5 Treated PNH Patients With Anemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-05-12
Completion: 2025-12-25
Conditions
Paroxysmal Nocturnal Haemoglobinuria (PNH)
Interventions
DRUG
No Results Yet
NCT07048730 | RECRUITING | NA
80 Participants

Gynecological Impact of Allogeneic Hematopoietic Stem Cell Transplantation in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-09-19
Completion: 2026-07-31
Conditions
Acute Leukemia
Interventions
OTHER
No Results Yet
NCT07048366 | RECRUITING | NA
44 Participants

Mindfulness-based Rehabilitation in a University Museum Setting to Reduce Pain and Improve Quality of Life in Women With Fibromyalgia: a Randomized Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-11-27
Completion: 2026-02-10
Conditions
Fibromyalgia Chronic Pain Musculoskeletal Pain
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07046949 | COMPLETED | NA
56 Participants

Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-07-07
Completion: 2025-12-08
Conditions
Uterine Bleeding Uterine Neoplasms Uterine Diseases Uterine Fibroids
Interventions
PROCEDURE DRUG
No Results Yet
NCT07046351 | RECRUITING | NA
744 Participants

weSIPsmarter: Evaluating a Digital Health Intervention Aimed at Reducing Sugary Drinks Among Rural Head Start Preschoolers and Their Parents

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-08-06
Completion: 2028-02-01
Conditions
Sugary Beverages
Interventions
BEHAVIORAL
No Results Yet
NCT07041879 | ACTIVE_NOT_RECRUITING | NA
30 Participants

Piezotome Atraumatic Tooth Extraction And Immediate Implant Placement In Maxillary Anterior Region

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-10-01
Completion: 2025-09-30
Conditions
Piezotome Implant-supported Single Crowns
Interventions
PROCEDURE
No Results Yet
NCT07030972 | ENROLLING_BY_INVITATION | NA
42 Participants

Effect of Deep Friction Massage on Pain, Function, Kinesiophobia, and Quality of Life in Bicipital Tendinitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-12-20
Completion: 2025-12-20
Conditions
Bicipital Tendonitis
Interventions
OTHER
No Results Yet
NCT07027839 | RECRUITING | PHASE1
30 Participants

Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-12-11
Completion: 2028-02-22
Conditions
Alcohol Use Disorder
Interventions
DRUG
No Results Yet
NCT07026461 | RECRUITING | PHASE4
350 Participants

Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulation (iTBS) in Patients With Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-12-15
Completion: 2030-12-31
Conditions
Depression - Major Depressive Disorder Depression Bipolar
Interventions
DEVICE
No Results Yet
NCT07011342 | RECRUITING | NA
70 Participants

Utility of 18F-rhPSMA-7.3 in the Diagnosis of Prostate Cancer After Focal Gland Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-10-01
Completion: 2028-11-30
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT07011030 | COMPLETED | NA
72 Participants

Diagnosis of Sarcopenia in Older Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-09-23
Completion: 2025-12-04
Conditions
Sarcopenia
Interventions
OTHER
No Results Yet
NCT07007208 | NOT_YET_RECRUITING | PHASE2
100 Participants

Biomarkers of the Locus Coeruleus Nucleus: Links With Early Tau Pathology, Cognition and Alzheimer's Disease Risk

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-01-01
Completion: 2029-01-31
Conditions
Alzheimer Disease
Interventions
DRUG OTHER
No Results Yet
NCT07004764 | NOT_YET_RECRUITING | PHASE1
15 Participants

Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-03-31
Completion: 2027-03-31
Conditions
Achilles Tendon Repairs/Reconstructions Pilon Fracture of Tibia Tibial Plateau Fracture Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar) Calcaneus Fractures Talus Fracture Wound Infection Deep Wound Infection Post-Traumatic Wound Dehiscence, Surgical
Interventions
DRUG
No Results Yet
NCT06999980 | NOT_YET_RECRUITING | PHASE2
494 Participants

Neo IRENIE (NEOadjuvant Ipilimumab, RElatlimab, NIvolumab Evaluation)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-01-31
Completion: 2028-03-31
Conditions
Cutaneous Melanoma Mucosal Melanoma
Interventions
DRUG
No Results Yet
NCT06999564 | COMPLETED | NA
60 Participants

Effects of EFT on Postpartum Safety Perception, Anxiety, and Postoperative Pain After Cesarean Section

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-06-02
Completion: 2025-12-01
Conditions
Pain Management Anxiety
Interventions
BEHAVIORAL
No Results Yet
NCT06996951 | RECRUITING | PHASE3
64 Participants

Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-07-02
Completion: 2026-07-31
Conditions
Cystic Fibrosis (CF) Chronic Rhinosinusitis (CRS)
Interventions
DRUG OTHER
No Results Yet
NCT06996639 | RECRUITING | NA
400 Participants

Breaking Fasts Ahead of Cardiac Caths

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-10-13
Completion: 2026-06-30
Conditions
Stable Angina (SA) Unstable Angina (UA) NSTEMI - Non-ST Segment Elevation MI
Interventions
BEHAVIORAL
No Results Yet
NCT06990308 | ENROLLING_BY_INVITATION | NA
88 Participants

Deflated and Inflated Cuff Endotracheal Extubations

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-06-17
Completion: 2026-09-30
Conditions
Anesthesia Airway Management Respiratory Complications
Interventions
PROCEDURE
No Results Yet
NCT06985901 | NOT_YET_RECRUITING | NA
60 Participants

Evaluation of the Efficacy of Pulmonary Vein Isolation by Pulsed-field Ablation in Persistent Atrial Fibrillation: a Multicenter Study With Follow-up by Implantable Cardiac Monitor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-03-31
Completion: 2029-07-31
Conditions
Persistent Atrial Fibrillation
Interventions
PROCEDURE
No Results Yet
NCT06982937 | COMPLETED | NA
44 Participants

Mechanistic Drivers of Acute PAPE Responsiveness: Muscle Architecture, Contractile Kinetics, and Excitability in a Randomized Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-02-02
Completion: 2025-06-25
Conditions
Neuromuscular Function Muscle Activation Postactivation Potentiation Ultrasonography Tensiomyography Contraction MHC-I
Interventions
OTHER
Results Available
NCT06981819 | COMPLETED
147 Participants

Establishment and Effectiveness Evaluation of a Training System for Confocal Laser Endomicroscopy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2025-06-02
Completion: 2025-10-31
Conditions
Gastric Cancer Gastric High-grade Intraepithelial Neoplasia Gastric Low-grade Intraepithelial Neoplasia Gastritis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06979869 | RECRUITING
300 Participants

Investigating Multigene Methylation Dynamics in Treatment Response Surveillance for Esophageal Carcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2025-05-26
Completion: 2030-03-01
Conditions
Esophageal Cancer
Interventions
OTHER
No Results Yet
NCT06974786 | RECRUITING | PHASE2
100 Participants

Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-08-08
Completion: 2032-11-30
Conditions
Multiple Myeloma, Newly Diagnosed Multiple Myeloma (MM)
Interventions
DRUG PROCEDURE
No Results Yet
NCT06963151 | NOT_YET_RECRUITING | NA
66 Participants

Association of a HABIT-ILE Course and a Home Programme on the Bimanual Performance of Children With Cerebral Palsy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-01-01
Completion: 2026-01-01
Conditions
Cerebral Palsy
Interventions
OTHER
No Results Yet
NCT06944223 | RECRUITING | NA
24 Participants

Oxalate and Citrate in Humans - Response to Citrate

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-10-01
Completion: 2026-12-01
Conditions
Kidney Stone Healthy
Interventions
OTHER
No Results Yet
NCT06937892 | RECRUITING | NA
86 Participants

Transdiagnostic Metacognitive Therapy Compared to Disorder-Specific Cognitive-Behavioral Therapy for Anxiety Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-08-27
Completion: 2028-12-31
Conditions
Generalized Anxiety Disorder (GAD) Social Anxiety Disorder (SAD) Posttraumatic Stress Disorder (PTSD)
Interventions
BEHAVIORAL
No Results Yet
NCT06937203 | RECRUITING | PHASE1/PHASE2
126 Participants

Study of ARO-ALK7 in Adult Volunteers With Obesity With and Without Type 2 Diabetes Mellitus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-05-07
Completion: 2026-07-31
Conditions
Obesity Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT06927492 | COMPLETED | NA
50 Participants

Cognitive Sensorimotor Training With Whole Body Vibration for Cognitive Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-04-30
Completion: 2025-10-30
Conditions
Cognitive Impairment
Interventions
OTHER
No Results Yet
NCT06923397 | RECRUITING | NA
24 Participants

Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-06-05
Completion: 2026-11-28
Conditions
Lymphoma Lymphoma, Hodgkin Lymphoma, Non-Hodgkin Sedentary Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT06921369 | NOT_YET_RECRUITING | NA
60 Participants

The Effect of Compassionate Care Education on Nurses

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-12-20
Completion: 2026-01-16
Conditions
Nursing Compassion
Interventions
OTHER
No Results Yet
NCT06919016 | ACTIVE_NOT_RECRUITING | PHASE1
45 Participants

A Study to Evaluate the Safety and Immunogenicity of the V3-region Directed Immunogens DV700P-RNA Followed by DV701B1.1-RNA in Adults Without HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-08-06
Completion: 2027-03-25
Conditions
HIV-1-infection
Interventions
BIOLOGICAL
No Results Yet
NCT06918665 | SUSPENDED | PHASE1
52 Participants

HEALTH Trial - Healthy Adult Evaluation of Ivermectin Bioequivalence: Infant Versus Standard Formulation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-05-31
Completion: 2027-07-01
Conditions
Scabies
Interventions
DRUG
No Results Yet
NCT06911372 | RECRUITING | PHASE1
84 Participants

The Impact of Gestational Diabetes Mellitus on Cerebral Blood Flow and Cerebrovascular Function After Pregnancy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-08-22
Completion: 2027-04-15
Conditions
Gestational Diabetes Mellitus (GDM) Postpartum Women Uncomplicated Pregnancy
Interventions
DRUG OTHER
No Results Yet
NCT06907875 | RECRUITING | PHASE1/PHASE2
12 Participants

A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-05-08
Completion: 2031-03-31
Conditions
Facioscapulohumeral Muscular Dystrophy
Interventions
BIOLOGICAL
No Results Yet
NCT06902545 | RECRUITING
377 Participants

A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2025-04-03
Completion: 2030-07-31
Conditions
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer Metastatic Gastric Adenocarcinoma or Cancer Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06899971 | NOT_YET_RECRUITING
100 Participants

The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2026-02-01
Completion: 2026-12-31
Conditions
Cardiac Surgery Requiring Cardiopulmonary Bypass Brain Injury Congenital Heart Defect
Interventions
OTHER
No Results Yet
NCT06898684 | RECRUITING | NA
15 Participants

Medulloblastoma Online Video-based Exercise Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-12-09
Completion: 2026-12-31
Conditions
Medulloblastoma, Childhood
Interventions
BEHAVIORAL
No Results Yet
NCT06897839 | RECRUITING | PHASE2/PHASE3
366 Participants

Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developing Bronchopulmonary Dysplasia (BPD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-02-03
Completion: 2028-03-31
Conditions
Bronchopulmonary Dysplasia
Interventions
OTHER DRUG
No Results Yet
NCT06896279 | RECRUITING | NA
20 Participants

Study on the Effectiveness and Safety of Temporal Interference Stimulation in Treating Patients With Severe Consciousness Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-04-21
Completion: 2026-05-16
Conditions
Disorder of Consciousness Temporal Interference Stimulation
Interventions
PROCEDURE
No Results Yet
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