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Clinical Trials

Showing trials with last updates posted in 2025.

NCT05110300 | TERMINATED | NA
114 Participants

A Multisite Exploration of Balance Perturbations With and Without Body Weight Support

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-12-15
Completion: 2023-11-06
Conditions
Stroke Stroke, Acute Balance; Distorted Balance; Impairment Gait, Unsteady
Interventions
DEVICE
Results Available
NCT05086393 | COMPLETED | PHASE4
241 Participants

Duloxetine RCT on Postop TKA Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-11-01
Completion: 2025-06-01
Conditions
Pain, Postoperative Total Knee Arthroplasty
Interventions
DRUG
No Results Yet
NCT05085457 | COMPLETED | NA
540 Participants

The Use of ExPreS in the Weaning of Patients in Invasive Mechanical Ventilation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-11-01
Completion: 2024-12-30
Conditions
Respiratory Insufficiency
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05083416 | COMPLETED | NA
29 Participants

Effect of Prolonged Nightly Fasting on Immunotherapy Outcomes in HNSCC - Role of Gut Microbiome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-10-20
Completion: 2023-03-31
Conditions
Head and Neck Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05078970 | RECRUITING | NA
306 Participants

Advancing Suicide Intervention Strategies for Teens During High Risk Periods

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-08-11
Completion: 2027-01-31
Conditions
Suicide Attempts Suicidal Ideation Suicide and Self-harm Suicide Threat
Interventions
BEHAVIORAL
No Results Yet
NCT05064878 | ACTIVE_NOT_RECRUITING | PHASE3
87 Participants

A Study to Investigate the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-08
Completion: 2027-11-08
Conditions
CDKL5 Deficiency Disorder Generalized Tonic Clonic Seizure Epileptic Spasm Refractory Seizures
Interventions
DRUG
No Results Yet
NCT05064423 | COMPLETED | NA
85 Participants

Clinical Trials Outreach & Education

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-06-15
Completion: 2022-03-23
Conditions
Knowledge, Attitudes, Practice
Interventions
BEHAVIORAL
No Results Yet
NCT05055830 | RECRUITING
2000 Participants

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2021-10-05
Completion: 2027-10-30
Conditions
Cardiac Disease Critically Ill Children, Adult
Interventions
DRUG
No Results Yet
NCT05045027 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
36 Participants

Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-09-01
Completion: 2026-09-10
Conditions
Glioma Malignant Glioma Recurrent Glioma Recurrent Malignant Glioma
Interventions
PROCEDURE
No Results Yet
NCT05044845 | COMPLETED
150 Participants

Needs Assessment of Knowledge, Beliefs, and Attitudes of Patients With Hemophilia B About Gene Therapy

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2022-01-18
Completion: 2025-10-14
Conditions
Gene Therapy Hemophilia B
Interventions
BEHAVIORAL
No Results Yet
NCT05040373 | RECRUITING
10 Participants

Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2020-08-01
Completion: 2030-10-12
Conditions
Hereditary Transthyretin-mediated (hATTR) Amyloidosis Polyneuropathy
No Results Yet
NCT05030038 | RECRUITING
25 Participants

Oral Aromatase Inhibitors Modify the Gut Microbiome

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-29
Completion: 2026-04-30
Conditions
Breast Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT05024929 | RECRUITING
32 Participants

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2021-07-16
Completion: 2031-02-01
Conditions
Papillary Thyroid Cancer Pediatric Cancer Differentiated Thyroid Cancer
Interventions
PROCEDURE
No Results Yet
NCT05015426 | ACTIVE_NOT_RECRUITING | PHASE1
20 Participants

Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCT

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-03-21
Completion: 2025-08-30
Conditions
Acute Myeloid Leukemia
Interventions
BIOLOGICAL
No Results Yet
NCT05014282 | ACTIVE_NOT_RECRUITING | NA
638 Participants

Automated Video-Assisted Smoking Treatment for People Living With HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-12-15
Completion: 2025-09-23
Conditions
Smoking Cessation
Interventions
DRUG BEHAVIORAL
No Results Yet
NCT05004662 | ACTIVE_NOT_RECRUITING | NA
520 Participants

Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-12-01
Completion: 2025-07-01
Conditions
Smoking Cessation
Interventions
BEHAVIORAL DRUG
No Results Yet
NCT04982835 | ACTIVE_NOT_RECRUITING | NA
156 Participants

M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-07-26
Completion: 2025-12-31
Conditions
Cervical Disc Degenerative Disorder
Interventions
DEVICE
No Results Yet
NCT04970056 | RECRUITING
10000 Participants

Pancreatic Cancer Early Detection Consortium

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2020-09-18
Completion: 2030-12-31
Conditions
Pancreas Cancer Pancreas Cyst Pancreatic Ductal Adenocarcinoma Genetic Predisposition
No Results Yet
NCT04965675 | RECRUITING | PHASE3
285 Participants

A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-06-30
Completion: 2026-09-05
Conditions
Chronic Migraine in Children
Interventions
DRUG
No Results Yet
NCT04960579 | RECRUITING | PHASE1
275 Participants

P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-05-05
Completion: 2029-03-31
Conditions
Multiple Myeloma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT04959279 | SUSPENDED | NA
26 Participants

ED-TREAT (Early Detection and Treatment to Reduce Events With Agitation Tool) Compared to Usual Care

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2026-03-31
Completion: 2026-09-30
Conditions
Psychomotor Agitation Behavioral Disorder
Interventions
OTHER
No Results Yet
NCT04945369 | RECRUITING | NA
114 Participants

Follow-up During the Peripubertal Period of Preterm Children Included in the Protocol Entitled "EPIPOD".

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-02-02
Completion: 2028-02-02
Conditions
Preterm Children
Interventions
OTHER
No Results Yet
NCT04937400 | ACTIVE_NOT_RECRUITING
1040 Participants

Delirium in Children Undergoing Stem Cell Transplantation

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2021-07-12
Completion: 2026-07-30
Conditions
Stem Cell Transplant Complications Delirium
Interventions
OTHER
No Results Yet
NCT04924075 | RECRUITING | PHASE2
322 Participants

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2ฮฑ Related Genetic Alterations (MK-6482-015)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-08-12
Completion: 2029-06-04
Conditions
Pheochromocytoma/Paraganglioma Pancreatic Neuroendocrine Tumor Von Hippel-Lindau Disease Advanced Gastrointestinal Stromal Tumor HIF-2ฮฑ Mutated Cancers
Interventions
DRUG
No Results Yet
NCT04923958 | RECRUITING | NA
26436 Participants

Rapid Research in Diagnostics Development for TB Network

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-04-14
Completion: 2031-05-31
Conditions
Tuberculosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04902508 | ACTIVE_NOT_RECRUITING | NA
200 Participants

Evaluation of an Explicit Approach

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-02-15
Completion: 2026-01-30
Conditions
Developmental Language Disorder Explicit Intervention Grammatical Language
Interventions
BEHAVIORAL
No Results Yet
NCT04895033 | COMPLETED | NA
52 Participants

Brain Responses to Contextual Influences on Drinking Decisions

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-02-01
Completion: 2025-07-31
Conditions
Alcohol Drinking
Interventions
BEHAVIORAL
No Results Yet
NCT04876391 | COMPLETED | PHASE2
45 Participants

A Study Investigating Long-term Treatment With Spesolimab in People With a Skin Disease Called Hidradenitis Suppurativa Who Completed a Previous Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-08-24
Completion: 2024-04-26
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
Results Available
NCT04833907 | ENROLLING_BY_INVITATION | PHASE1/PHASE2
24 Participants

rAAV-Olig001-ASPA Gene Therapy for Treatment of Children With Typical Canavan Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-04-01
Completion: 2026-08-31
Conditions
Canavan Disease
Interventions
DRUG
No Results Yet
NCT04833829 | ACTIVE_NOT_RECRUITING | NA
850 Participants

Cross-disciplinary HIV Integrated Mental Health Support Intervention

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2020-11-01
Completion: 2026-11-30
Conditions
Human Immunodeficiency Virus HIV Infections
Interventions
BEHAVIORAL
No Results Yet
NCT04829604 | ACTIVE_NOT_RECRUITING | PHASE2
71 Participants

ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-10-26
Completion: 2026-12-31
Conditions
HER2 Positive Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT04802603 | RECRUITING | NA
60 Participants

Dose-Escalated Spine SbRT for Localized Metastasis to the Spinal Column

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-03-14
Completion: 2029-09-28
Conditions
Spine Metastases Metastasis Spine
Interventions
RADIATION
No Results Yet
NCT04801797 | RECRUITING | PHASE2
172 Participants

Venetoclax + Azacitidine vs. Induction Chemotherapy in AML

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-05-20
Completion: 2027-01-01
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT04798261 | RECRUITING
1500 Participants

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2021-06-25
Completion: 2026-12-31
Conditions
Pulmonary Embolism
Interventions
DEVICE
No Results Yet
NCT04775004 | RECRUITING | NA
146 Participants

Comparing Meniscal Repair Biologic Augmentation: Marrow Venting Procedure Versus PRP (MVP Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-07-19
Completion: 2026-12-31
Conditions
Meniscal Tear
Interventions
OTHER
No Results Yet
NCT04773782 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
37 Participants

A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-02-24
Completion: 2025-11-30
Conditions
Solid Tumor, Unspecified, Child Relapsed Solid Neoplasm CNS Tumor
Interventions
DRUG
No Results Yet
NCT04710056 | AVAILABLE

Expanded Access to REGN4461 for Patients With Lipodystrophy or Monogenic Obesity With Complications of Leptin Deficiency or Deficient Leptin Signaling

Study Type: EXPANDED_ACCESS
Last Updated: 2025-11-14
Conditions
Lipodystrophy
Interventions
DRUG
No Results Yet
NCT04707872 | RECRUITING
300 Participants

Trifecta-Heart cfDNA-MMDx Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2021-06-01
Completion: 2026-12-31
Conditions
Heart Transplant Rejection
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04706026 | RECRUITING | NA
80 Participants

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-10-23
Completion: 2026-08-31
Conditions
Inguinal Hernia Anesthesia, Local
Interventions
OTHER
No Results Yet
NCT04689828 | ACTIVE_NOT_RECRUITING | PHASE3
469 Participants

177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-06-15
Completion: 2022-10-02
Conditions
Prostatic Neoplasms
Interventions
DRUG
Results Available
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