Clinical Trials
Showing trials with last updates posted in 2025.
64
Participants
A Study of TAS-120 in Patients With Metastatic Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2020-01-28
Completion:
2023-05-31
Conditions
Metastatic Breast Cancer
FGFR 1 High Amplification
FGFR2 Amplification
Interventions
DRUG
120
Participants
CPT-SMART for Treatment of PTSD and Cigarette Smoking
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-11-07
Completion:
2025-10-08
Conditions
Smoking
Stress Disorders, Post-Traumatic
Interventions
BEHAVIORAL
DRUG
No Results Yet
288
Participants
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-09-16
Completion:
2029-12-31
Conditions
Smoldering Plasma Cell Myeloma
Interventions
BIOLOGICAL
DRUG
OTHER
No Results Yet
1236
Participants
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2020-07-28
Completion:
2026-02-28
Conditions
Anterior Cruciate Ligament Injury
Anterior Cruciate Ligament Reconstruction
Joint Instability
Interventions
PROCEDURE
No Results Yet
200
Participants
A Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Participants With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-04-26
Completion:
2024-04-04
Conditions
Multiple Myeloma
Interventions
DRUG
1500
Participants
Pan Tumor Rollover Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-08-09
Completion:
2029-08-25
Conditions
Cancer
Interventions
DRUG
No Results Yet
5
Participants
Gene Therapy Trial for Platelet Derived Factor VIII Production in Hemophilia A
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2020-04-29
Completion:
2026-03-31
Conditions
Hemophilia A
Interventions
BIOLOGICAL
No Results Yet
0
Participants
Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2019-01-08
Completion:
2020-05-29
Conditions
Breast Carcinoma
Colorectal Carcinoma
Community Practice
Lung Carcinoma
Melanoma
Solid Neoplasm
Interventions
OTHER
No Results Yet
90
Participants
Genesis Electrical Impedance Tomography (EIT): A Preliminary Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2019-05-03
Completion:
2026-11-30
Conditions
Premature Infant
Chronic Respiratory Disease
Neuromuscular Diseases
Healthy
Bronchopulmonary Dysplasia
Pulmonary Vein Stenoses
No Results Yet
35
Participants
Mild-Intensity Whole Body Hyperthermia (WBH) for Major Depressive Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-12-01
Completion:
2028-12-01
Conditions
Major Depressive Disorder
Interventions
DRUG
DEVICE
No Results Yet
48
Participants
LET Optimized IMPT in Treating Pediatric Patients With Ependymoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-04-01
Completion:
2027-12-31
Conditions
Anaplastic Ependymoma
Ependymoma
Interventions
RADIATION
OTHER
No Results Yet
765
Participants
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-01-25
Completion:
2021-10-08
Conditions
Castration-Resistant Prostatic Cancer
Interventions
DRUG
12
Participants
Burst Spinal Cord Stimulation (Burst-SCS) Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-03-12
Completion:
2020-03-10
Conditions
Pain, Chronic
Failed Back Surgery Syndrome
Interventions
DEVICE
63
Participants
Validation of RPVi as a Parameter to Predict Fluid Responsiveness
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-09-24
Completion:
2021-10-20
Conditions
Surgery
Anesthesia
Interventions
DEVICE
852
Participants
Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-02-11
Completion:
2025-12-31
Conditions
Prostate Carcinoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
99
Participants
Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-09-12
Completion:
2021-09-03
Conditions
Depression
Anxiety
Generalized Anxiety Disorder
Depressive Disorder
Major Depressive Disorder
Cancer
Interventions
DIAGNOSTIC_TEST
OTHER
No Results Yet
49
Participants
Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing Tenofovir
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-01-02
Completion:
2019-09-25
Conditions
HIV Infections
Interventions
DRUG
56
Participants
A Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-04-29
Completion:
2029-01-31
Conditions
Secondary Hyperparathyroidism
Chronic Kidney Disease
Interventions
DRUG
No Results Yet
200
Participants
Image Guided VATS vs. VATS Resection
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-09-11
Completion:
2027-07-31
Conditions
Lung Cancer
Interventions
DEVICE
PROCEDURE
No Results Yet
38
Participants
Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-11-06
Completion:
2023-03-31
Conditions
Anaplastic Astrocytoma
Glioblastoma
Malignant Glioma
Interventions
RADIATION
DRUG
206
Participants
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-11-22
Completion:
2027-06-30
Conditions
Brain Metastases
Interventions
DRUG
RADIATION
PROCEDURE
No Results Yet
156
Participants
Parent-Level Predictors of Early Language Interaction Quality and Intervention Outcomes
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2021-03-22
Completion:
2025-09-18
Conditions
Language Development Disorders
Autism Spectrum Disorder
Interventions
BEHAVIORAL
OTHER
No Results Yet
101
Participants
ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-09-18
Completion:
2020-10-02
Conditions
Aortic Valve Stenosis
Interventions
DEVICE
40
Participants
Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-06-26
Completion:
2028-08-31
Conditions
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Minimal Residual Disease
Interventions
DRUG
OTHER
BIOLOGICAL
No Results Yet
74
Participants
Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-08-03
Completion:
2025-12-31
Conditions
Recurrent Adult Lymphoblastic Lymphoma
Recurrent B Acute Lymphoblastic Leukemia
Recurrent B Lymphoblastic Lymphoma
Recurrent T Acute Lymphoblastic Leukemia
Recurrent T Lymphoblastic Lymphoma
Refractory B Acute Lymphoblastic Leukemia
Refractory B Lymphoblastic Lymphoma
Refractory T Acute Lymphoblastic Leukemia
Refractory T Lymphoblastic Lymphoma
Interventions
PROCEDURE
DRUG
No Results Yet
82
Participants
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2019-03-12
Completion:
2029-03-31
Conditions
Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7
Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7
Interventions
DRUG
RADIATION
OTHER
PROCEDURE
No Results Yet
2140
Participants
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-10-16
Completion:
2027-09-01
Conditions
Breast Cancer
Interventions
RADIATION
OTHER
No Results Yet
211
Participants
A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-04-17
Completion:
2021-02-26
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Interventions
DRUG
120
Participants
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-07-11
Completion:
2023-07-19
Conditions
Psoriasis
Interventions
DRUG
62
Participants
An Early Stress-Reduction Intervention in Patients With Newly Diagnosed Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-12-05
Completion:
2026-04-30
Conditions
Malignant Neoplasm of Breast
Interventions
BEHAVIORAL
No Results Yet
223
Participants
Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-04-26
Completion:
2026-03-31
Conditions
Castration Levels of Testosterone
Castration-Resistant Prostate Carcinoma
Metastatic Prostate Carcinoma in the Soft Tissue
Prostate Carcinoma Metastatic in the Bone
Stage IV Prostate Adenocarcinoma AJCC v7
Interventions
DRUG
OTHER
PROCEDURE
No Results Yet
629
Participants
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-03-23
Completion:
2024-04-15
Conditions
Urothelial Cancer
Interventions
DRUG
DEVICE
150
Participants
Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and Other Genitourinary Tumors With DNA-Repair Genetic Changes
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2020-11-03
Completion:
2025-12-16
Conditions
Advanced Bladder Carcinoma
Advanced Genitourinary System Carcinoma
Metastatic Bladder Carcinoma
Metastatic Genitourinary System Carcinoma
Stage III Bladder Cancer AJCC v8
Stage IV Bladder Cancer AJCC v8
Interventions
PROCEDURE
DRUG
No Results Yet
1214
Participants
AMPLATZER PFO Occluder Post Approval Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-01-31
Completion:
2030-02-05
Conditions
Stroke
Patent Foramen Ovale
Interventions
DEVICE
No Results Yet
689
Participants
Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-11-27
Completion:
2027-01-31
Conditions
Mantle Cell Lymphoma
Interventions
PROCEDURE
BIOLOGICAL
No Results Yet
108508
Participants
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-09-28
Completion:
2028-12-31
Conditions
Breast Screening
Interventions
PROCEDURE
OTHER
No Results Yet
146
Participants
DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-07-25
Completion:
2025-12-31
Conditions
Gliosarcoma
Recurrent Glioblastoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
32
Participants
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2018-07-09
Completion:
2025-08-15
Conditions
Glioblastoma
Gliosarcoma
MGMT-Unmethylated Glioblastoma
Recurrent Glioblastoma
Interventions
PROCEDURE
DRUG
RADIATION
No Results Yet
220
Participants
The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2024-04-16
Completion:
2027-08-31
Conditions
Intracranial Aneurysm
Interventions
DEVICE
No Results Yet
24
Participants
Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-05-01
Completion:
2024-11-15
Conditions
Pleural Malignant Mesothelioma
Interventions
OTHER
RADIATION
BIOLOGICAL
Showing 40 trials per page · Total 107903 trials