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Clinical Trials

NCT06780670 | RECRUITING | PHASE2/PHASE3
432 Participants

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-02-27
Completion: 2028-06-27
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06776783 | RECRUITING | PHASE3
520 Participants

Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-24
Completion: 2027-05-31
Conditions
Respiratory Distress Syndrome Pre-term Infants
Interventions
COMBINATION_PRODUCT OTHER
No Results Yet
NCT06757647 | SUSPENDED | PHASE2
61 Participants

Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-27
Completion: 2026-12-31
Conditions
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT06755827 | NOT_YET_RECRUITING | PHASE1/PHASE2
30 Participants

Pilot Testing a Novel Approach to Pediatric Obesity Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2025-12-31
Conditions
Overweight Adolescents Obese Adolescents
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06751602 | ENROLLING_BY_INVITATION | PHASE2
40 Participants

Belumosudil for Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-11
Completion: 2027-12-31
Conditions
Rejection Chronic Renal
Interventions
DRUG
No Results Yet
NCT06741072 | SUSPENDED | PHASE1
55 Participants

BZLF1 Peptide Vaccine (OSU-2131) With QS-21 for the Prevention of Epstein-Barr Virus Related Cancer in Patients Awaiting Solid Organ Transplants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2026-12-31
Conditions
Chronic Kidney Disease, Stage 4 Chronic Kidney Disease, Stage 5 EBV-Related Lymphoproliferative Disorder EBV-Related Malignant Neoplasm Post-Transplant Lymphoproliferative Disorder
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06739668 | ACTIVE_NOT_RECRUITING | NA
30 Participants

Humanity Neurotech Device Clinical Trial in Adults With Long COVID Cognitive Dysfunction

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-19
Completion: 2025-12-31
Conditions
Post-Acute COVID-19 Syndrome Cognitive Dysfunction
Interventions
DEVICE
No Results Yet
NCT06735690 | RECRUITING | EARLY_PHASE1
15 Participants

Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-06-09
Completion: 2029-03-07
Conditions
Acute Lymphoblastic Leukemia
Interventions
PROCEDURE BIOLOGICAL OTHER
No Results Yet
NCT06732440 | NOT_YET_RECRUITING | NA
48 Participants

Subthreshold Vestibular Stimulation as a Strategy for Rehabilitation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2026-12-31
Conditions
Vestibular Hypofunction Bilateral Vestibular Hypofunction Presbyvestibulopathy Healthy Controls
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06730347 | RECRUITING | PHASE2
60 Participants

A Study of Lorigerlimab in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-01
Completion: 2027-02-28
Conditions
Platinum-resistant Ovarian Cancer Platinum-Resistant Fallopian Tube Carcinoma Platinum-Resistant Primary Peritoneal Carcinoma Clear Cell Adenocarcinoma of Ovary Clear Cell Adenocarcinoma of Vulva Clear Cell Adenocarcinoma of Vagina Clear Cell Adenocarcinoma of Cervix Clear Cell Adenocarcinoma of Uterus Clear Cell Adenocarcinoma of Fallopian Tube Clear Cell Adenocarcinoma of Peritoneum Endometrial Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT06729398 | COMPLETED | NA
129 Participants

The Role of Cerebral NIRS in Preventing Brain Injury of Very Low Birth Weight Preterm Infants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2017-05-01
Completion: 2020-05-01
Conditions
Neonatal Cerebral Leukomalacia Intracranial Nontraumatic Haemorrhage of Fetus and Newborn Neonatal Mortality
Interventions
DEVICE OTHER
No Results Yet
NCT06717451 | ACTIVE_NOT_RECRUITING
144 Participants

PS230005 Control-IQ 1.5 Post-Approval Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-30
Completion: 2026-08-11
Conditions
Type 1 Diabetes
Interventions
DEVICE
No Results Yet
NCT06717347 | RECRUITING | PHASE3
1046 Participants

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-27
Completion: 2029-07-02
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06697600 | RECRUITING | NA
640 Participants

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-11
Completion: 2029-10-01
Conditions
Oncology Myeloid Leukemia, Acute Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06697301 | RECRUITING | PHASE2/PHASE3
740 Participants

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-22
Completion: 2035-12-31
Conditions
Advanced Melanoma
Interventions
DRUG
No Results Yet
NCT06693310 | NOT_YET_RECRUITING | NA
200 Participants

STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2026-11-30
Conditions
Ulcerative Colitis (UC)
Interventions
OTHER
No Results Yet
NCT06692192 | RECRUITING | PHASE1
60 Participants

The RECAP2 Study: Midazolam and Psilocybin

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-07
Completion: 2027-12-31
Conditions
Psilocybin
Interventions
DRUG
No Results Yet
NCT06691113 | ACTIVE_NOT_RECRUITING | PHASE2
60 Participants

A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti--IL-33 mAb) in Participants With Chronic Rhinosinusitis Without Nasal Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-16
Completion: 2026-08-07
Conditions
Chronic Rhinosinusitis Without Nasal Polyps
Interventions
DRUG
No Results Yet
NCT06685835 | ACTIVE_NOT_RECRUITING | PHASE2
214 Participants

A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-16
Completion: 2026-05-22
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT06685757 | RECRUITING | PHASE3
120 Participants

A Trial of Felzartamab in Kidney Transplant Recipients With Late Antibody-Mediated Rejection (AMR)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-03
Completion: 2026-12-01
Conditions
Antibody-mediated Rejection
Interventions
DRUG
No Results Yet
NCT06685718 | RECRUITING | PHASE1
93 Participants

A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-26
Completion: 2028-04-30
Conditions
Non-Small Cell Lung Cancer Lung Cancer NSCLC NSCLC (Non-small Cell Lung Carcinoma) EGFR Activating Mutation EGFR Mutation-Related Tumors
Interventions
DRUG
No Results Yet
NCT06682988 | RECRUITING | PHASE2
110 Participants

A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-28
Completion: 2028-03-31
Conditions
Advanced High-Grade Epithelial Ovarian Primary Peritoneal Fallopian Tube Cancers High Folate Receptor-Alpha Expression Platinum Resistant
Interventions
DRUG
No Results Yet
NCT06680830 | RECRUITING | PHASE2
150 Participants

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-01-17
Completion: 2026-09-30
Conditions
Parkinson Disease Parkinson Idiopathic Parkinson Disease Early Parkinson Disease (Early PD) Parkinson Disease, Idiopathic
Interventions
DRUG OTHER
No Results Yet
NCT06680479 | RECRUITING | PHASE1
30 Participants

Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-01
Completion: 2027-04-30
Conditions
HIV-1
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06679140 | RECRUITING | PHASE3
2330 Participants

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-08
Completion: 2026-12-06
Conditions
COVID-19 SARS-CoV-2 Infection
Interventions
DRUG
No Results Yet
NCT06670638 | RECRUITING
50 Participants

Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-19
Completion: 2026-06-30
Conditions
Crohns Disease
No Results Yet
NCT06662500 | RECRUITING | NA
158 Participants

FORWARD CAD IDE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-04
Completion: 2026-08-31
Conditions
Coronary Arterial Disease (CAD)
Interventions
DEVICE
No Results Yet
NCT06659640 | RECRUITING | PHASE1/PHASE2
120 Participants

A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-11
Completion: 2028-01-05
Conditions
Hereditary Hemorrhagic Telangiectasia
Interventions
DRUG
No Results Yet
NCT06655844 | RECRUITING | NA
30 Participants

Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-04
Completion: 2026-03-31
Conditions
Post-treatment Lyme Disease Syndrome Chronic Pain
Interventions
DEVICE
No Results Yet
NCT06654843 | RECRUITING | NA
630 Participants

Free Time For Wellness 2+

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-15
Completion: 2026-09-30
Conditions
Physical Inactivity
Interventions
BEHAVIORAL
No Results Yet
NCT06651632 | RECRUITING | NA
280 Participants

WATER IV Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-02-03
Completion: 2027-07-31
Conditions
Localized Prostate Cancer
Interventions
DEVICE PROCEDURE
No Results Yet
NCT06647498 | RECRUITING | PHASE2/PHASE3
280 Participants

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-22
Completion: 2034-03-31
Conditions
Alzheimers Disease Dementia Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
NCT06645145 | COMPLETED | NA
170 Participants

Language Learning and Language Experience

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-31
Completion: 2025-08-30
Conditions
Typically Developing Children Ages 3 to 6
Interventions
BEHAVIORAL
No Results Yet
NCT06644664 | RECRUITING | NA
300 Participants

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-24
Completion: 2026-08-31
Conditions
Tobacco-Related Carcinoma
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06643481 | ACTIVE_NOT_RECRUITING | PHASE2
251 Participants

A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-17
Completion: 2026-09-21
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06641466 | RECRUITING | PHASE3
723 Participants

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-11
Completion: 2026-11-29
Conditions
Menstrual Migraine
Interventions
DRUG
No Results Yet
NCT06638554 | RECRUITING | NA
6000 Participants

Integrating Telehealth to Advance Lung Cancer Screening

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-09
Completion: 2027-01-31
Conditions
Early Detection of Cancer Telemedicine Decision Making
Interventions
BEHAVIORAL
No Results Yet
NCT06637501 | ACTIVE_NOT_RECRUITING | PHASE2
94 Participants

A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-14
Completion: 2027-10-31
Conditions
Chronic Lymphocytic Leukemia
Interventions
DRUG
No Results Yet
NCT06636383 | RECRUITING
140 Participants

Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-04
Completion: 2036-12-31
Conditions
Glycogen Storage Disease Type Ia
Interventions
OTHER
No Results Yet
NCT06625593 | RECRUITING | PHASE1
168 Participants

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-12-09
Completion: 2026-12-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
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