Clinical Trials

NCT02262806 | ACTIVE_NOT_RECRUITING | PHASE2
29 Participants

Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2014-10-14
Completion: 2027-07-31
Conditions
Diabetes Lipodystrophy Hyperlipidemia
Interventions
DRUG
No Results Yet
NCT02257736 | ACTIVE_NOT_RECRUITING | PHASE3
982 Participants
NCT02143830 | RECRUITING | PHASE2
70 Participants

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2014-04-30
Completion: 2026-12-31
Conditions
Fanconi Anemia Severe Marrow Failure Myelodysplastic Syndrome (MDS) Acute Myelogenous Leukemia (AML)
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT02119611 | RECRUITING | NA
300 Participants

Deep Brain Stimulation Therapy in Movement Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2014-04-02
Completion: 2030-12-01
Conditions
Parkinson's Disease
Interventions
DEVICE
No Results Yet
NCT02055105 | RECRUITING
50 Participants

Modulation of Molecular Fingerprinting in Pediatric Sepsis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2014-03-31
Completion: 2027-06-30
Conditions
Systemic Inflammatory Response Syndrome
Interventions
PROCEDURE
No Results Yet
NCT02008045 | ACTIVE_NOT_RECRUITING
300 Participants

MR Imaging of Perinatal Brain Injury

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2009-07-01
Completion: 2028-12-31
Conditions
Perinatal White Matter Brain Injury
Interventions
DEVICE BEHAVIORAL
No Results Yet
NCT01946204 | ACTIVE_NOT_RECRUITING | PHASE3
1207 Participants

A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2013-10-14
Completion: 2017-05-19
Conditions
Prostatic Neoplasms
Interventions
DRUG
NCT01864109 | ACTIVE_NOT_RECRUITING | PHASE2
83 Participants

Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2013-05-31
Completion: 2027-05-31
Conditions
Newly Diagnosed Ewing Sarcoma
Interventions
DRUG DEVICE PROCEDURE RADIATION
No Results Yet
NCT01841723 | ACTIVE_NOT_RECRUITING | PHASE2
44 Participants

Ibrutinib in Treating Patients With Relapsed Hairy Cell Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2013-04-30
Completion: 2029-12-31
Conditions
Hairy Cell Leukemia Hairy Cell Leukemia Variant Recurrent Hairy Cell Leukemia Recurrent Hairy Cell Leukemia Variant
Interventions
PROCEDURE DRUG
No Results Yet
NCT01818661 | RECRUITING | PHASE4
50 Participants

Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2018-07-01
Completion: 2028-06-30
Conditions
PPA Non-fluent Aphasia Apraxia of Speech Primary Progressive Non-fluent Aphasia Primary Progressive Aphasia
Interventions
DRUG
No Results Yet
NCT01810913 | RECRUITING | PHASE2/PHASE3
613 Participants

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2013-03-22
Completion: 2027-01-01
Conditions
Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7 Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7 Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7 Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7
Interventions
DRUG PROCEDURE BIOLOGICAL RADIATION OTHER
No Results Yet
NCT01760005 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
490 Participants

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2012-12-31
Completion: 2028-04-30
Conditions
Alzheimers Disease Dementia Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
NCT01736501 | WITHDRAWN | NA
0 Participants

Surveying Parents About Genome Screening of Newborns

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Conditions
Parents of Healthy Newborns
Interventions
OTHER
No Results Yet
NCT01719055 | RECRUITING
4800 Participants

RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2012-11-19
Completion: 2035-05-31
Conditions
Pain
Interventions
DEVICE
No Results Yet
NCT01712620 | RECRUITING | PHASE2
70 Participants

Spironolactone for Pulmonary Arterial Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2014-01-10
Completion: 2026-12-31
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
No Results Yet
NCT01627041 | ACTIVE_NOT_RECRUITING | PHASE2
178 Participants

Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2011-09-16
Completion: 2016-02-11
Conditions
Acute Myeloid Leukemia Adult Acute Basophilic Leukemia Adult Acute Monoblastic Leukemia Adult Acute Monocytic Leukemia Adult Acute Myeloid Leukemia With Maturation Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-KMT2A Adult Acute Myeloid Leukemia Without Maturation Adult Acute Myelomonocytic Leukemia Alkylating Agent-Related Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia
Interventions
DRUG OTHER
No Results Yet
NCT01579552 | ACTIVE_NOT_RECRUITING | PHASE3
360 Participants

Promoting Breast Cancer Screening in Women Who Survived Childhood Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2010-07-31
Completion: 2026-07-31
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT01422694 | RECRUITING
2000 Participants

Natural History and Development of Spondyloarthritis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2011-08-12
Conditions
Arthritis Spondylitis, Ankylosing
No Results Yet
NCT01314118 | COMPLETED | PHASE2
131 Participants

IMAAGEN: Impact of Abiraterone Acetate in Prostate-Specific Antigen

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2011-05-04
Completion: 2013-12-24
Conditions
Prostate Cancer Prostatic Neoplasm
Interventions
DRUG
NCT01306084 | RECRUITING
1000 Participants

Viral Infections in Healthy and Immunocompromised Hosts

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2011-03-15
Conditions
Anogenital Herpes COVID-19 Herpes Labialis
No Results Yet
NCT01287000 | ACTIVE_NOT_RECRUITING
32658 Participants

Gulf Long-Term Follow-Up Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2011-03-24
Conditions
Cardiovascular Disease Hematologic Diseases Immunologic Disease Cancer Respiratory Function
No Results Yet
NCT01171898 | COMPLETED | PHASE1/PHASE2
127 Participants

Safety, Pharmacokinetic and Proof-of-Concept Study of ARN-509 (Apalutamide) in Castration-Resistant Prostate Cancer (CRPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2010-07-26
Completion: 2012-08-20
Conditions
Prostate Cancer
Interventions
DRUG
NCT01050296 | RECRUITING
1000 Participants

Molecular Analysis Of Solid Tumors

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2010-02-10
Completion: 2026-09-30
Conditions
Pediatric Solid Tumors
No Results Yet
NCT01019343 | COMPLETED | NA
1273 Participants

Physiological Investigations of Movement Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2009-12-08
Completion: 2016-08-17
Conditions
Parkinson's Disease Tourette's Syndrome Tic Disorders Dystonia Movement Disorders
Interventions
PROCEDURE DEVICE OTHER DIAGNOSTIC_TEST
No Results Yet
NCT00980954 | COMPLETED | PHASE3
236 Participants

Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2009-09-30
Completion: 2023-12-14
Conditions
Cervical Cancer
Interventions
DRUG RADIATION
NCT00923442 | ENROLLING_BY_INVITATION
550 Participants

Biology Studies of Hematologic Cancers

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2004-02-24
Conditions
Acute Lymphoblastic Leukemia Myelodysplastic Syndrome (MDS) Non-Hodgkins Lymphoma Acute Myelogenous Leukemia Hodgkins Lymphoma
No Results Yet
NCT00792155 | RECRUITING
1000 Participants

Polycystic Kidney Disease Data Repository

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2002-11-30
Completion: 2030-12-31
Conditions
Polycystic Kidney Disease
No Results Yet
NCT00489307 | ACTIVE_NOT_RECRUITING | PHASE2
132 Participants

Dexamethasone for Symptom Burden in Advanced Cancer Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2006-02-02
Completion: 2021-02-28
Conditions
Solid Tumors
Interventions
DRUG
NCT00342888 | COMPLETED
629 Participants

Case-Control Study of Pesticides and Childhood Leukemia

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2001-10-30
Conditions
Leukemia
No Results Yet
NCT00258570 | RECRUITING
2000 Participants

Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2003-01-31
Completion: 2035-07-31
Conditions
Pulmonary Fibrosis
No Results Yet
NCT00128973 | RECRUITING
3500 Participants

Evaluation of Patients With Immune Function Abnormalities

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2005-09-19
Conditions
Chronic Granulomatous Disease (CGD) X-Linked Severe Combined Immune Deficiency (XSCID) Leukocyte Adhesion Deficiency 1 (LAD) Graft Versus Host Disease (cGvHD)
No Results Yet
NCT00102544 | ENROLLING_BY_INVITATION | NA
3894 Participants

Use of Tracking Devices to Locate Abnormalities During Invasive Procedures

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2005-02-23
Completion: 2026-06-02
Conditions
Adenocarcinoma Prostate Neoplasms Prostate Cancer Renal Cell Carcinoma Von Hippel Lindau Disease
Interventions
DEVICE
No Results Yet
NCT00084305 | ACTIVE_NOT_RECRUITING
315 Participants

Analysis of Specimens From Individuals With Pulmonary Fibrosis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2004-06-09
Conditions
Pulmonary Fibrosis Healthy Volunteers Hermansky-Pudlak Syndrome (HPS)
No Results Yet
NCT00071786 | COMPLETED
1944 Participants

Family Study of Affective and Anxiety Spectrum Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2004-05-21
Conditions
Mood Disorders Sleep Disorders Migraine
No Results Yet
NCT00050752 | RECRUITING
1130 Participants

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2003-02-24
Conditions
Renal Tumor Histology Cutaneous Leiomyoma Kidney Cancer
No Results Yet
NCT00033137 | RECRUITING
950 Participants

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2002-05-13
Conditions
Kidney Neoplasms Kidney Cancer Pneumothorax FLCN Protein, Human
No Results Yet
NCT00018889 | RECRUITING
2500 Participants

Phenotype/Genotype Correlations in Movement Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2001-10-22
Conditions
Movement Disorder
No Results Yet
NCT00007150 | ACTIVE_NOT_RECRUITING | PHASE2
622 Participants

Treatment of Hemochromatosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2001-01-01
Completion: 2025-12-31
Conditions
Hemochromatosis
Interventions
PROCEDURE
No Results Yet
NCT00004568 | RECRUITING
3500 Participants

Study of Inherited Neurological Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2000-02-18
Conditions
Motor Neuron Disease Muscular Disease Muscular Dystrophy Peripheral Nervous System Disease
No Results Yet
NCT00001529 | RECRUITING
500 Participants

Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 1996-03-18
Conditions
Graft-Versus-Host Disease Graft-versus-leukemia Donor Apheresis
Interventions
DRUG
No Results Yet
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